ES8800156A1 - Procedimiento para preparar nuevos derivados 3-piridilmetilnaftilicos - Google Patents
Procedimiento para preparar nuevos derivados 3-piridilmetilnaftilicosInfo
- Publication number
- ES8800156A1 ES8800156A1 ES552871A ES552871A ES8800156A1 ES 8800156 A1 ES8800156 A1 ES 8800156A1 ES 552871 A ES552871 A ES 552871A ES 552871 A ES552871 A ES 552871A ES 8800156 A1 ES8800156 A1 ES 8800156A1
- Authority
- ES
- Spain
- Prior art keywords
- medicaments
- preparation
- pyridylmethylnaphthyl
- derivatives
- compounds
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D213/28—Radicals substituted by singly-bound oxygen or sulphur atoms
- C07D213/30—Oxygen atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D213/26—Radicals substituted by halogen atoms or nitro radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D213/36—Radicals substituted by singly-bound nitrogen atoms
- C07D213/42—Radicals substituted by singly-bound nitrogen atoms having hetero atoms attached to the substituent nitrogen atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D213/54—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D213/55—Acids; Esters
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Pyridine Compounds (AREA)
Abstract
PROCEDIMIENTO PARA PREPARAR NUEVOS DERIVADOS DE 3-PIRIDILMETILNAFTILO. CONSISTE EN METALAR EN POSICION 3 A UN COMPUESTO DE FORMULA (II) CON UN COMPUESTO DE FORMULA (III), PARA OBTENER UN COMPUESTO DE FORMULA (I) Y SUS SALES DE ADICION DE ACIDOS FISIOLOGICAMENTE COMPATIBLES. SIENDO. R ELEVADO A 1, H Y EN POSICIONES 2,4,5 O 6 HAL O UN RADICAL ALQUIL DE CADENA LINEAL O RAMIFICADO DE C 1 A 6; R ELEVADO A 2, HIDROXI, HAL, ALCOXI DE C 1 A 6 Y OTROS; R ELEVADO A 3, H, CICLOALQUILO DE C 3A 7 Y OTROS, R ELEVADO A 5, ALQUILO DE C 1 A 8; X, HAL; E Y, -COOR ELEVADO A 5. SE UTILIZAN PARA EL TRATAMIENTO DE ENFERMEDADES TROMBOTICAS (ANGINA DE PECHO, ARRITMIAS Y JAQUECAS). *FORMULA*
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE19853508903 DE3508903A1 (de) | 1985-03-13 | 1985-03-13 | Neue 3-pyridylmethylnaphtylderivate, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel |
Publications (2)
Publication Number | Publication Date |
---|---|
ES552871A0 ES552871A0 (es) | 1987-11-01 |
ES8800156A1 true ES8800156A1 (es) | 1987-11-01 |
Family
ID=6265029
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES552871A Expired ES8800156A1 (es) | 1985-03-13 | 1986-03-11 | Procedimiento para preparar nuevos derivados 3-piridilmetilnaftilicos |
ES557647A Expired ES8801633A1 (es) | 1985-03-13 | 1987-07-31 | Procedimiento para preparar nuevos derivados de 3-piridil-metilnaftilo |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES557647A Expired ES8801633A1 (es) | 1985-03-13 | 1987-07-31 | Procedimiento para preparar nuevos derivados de 3-piridil-metilnaftilo |
Country Status (9)
Country | Link |
---|---|
US (1) | US4734406A (es) |
EP (1) | EP0194579B1 (es) |
JP (1) | JPS61227568A (es) |
AT (1) | ATE62226T1 (es) |
DE (2) | DE3508903A1 (es) |
DK (1) | DK114286A (es) |
ES (2) | ES8800156A1 (es) |
GR (1) | GR860679B (es) |
PT (1) | PT82175B (es) |
Families Citing this family (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
NZ213986A (en) * | 1984-10-30 | 1989-07-27 | Usv Pharma Corp | Heterocyclic or aromatic compounds, and pharmaceutical compositions containing such |
GB9027258D0 (en) * | 1990-12-17 | 1991-02-06 | Erba Carlo Spa | Pyridyl derivatives of substituted bicyclic compounds and process for their preparation |
JP2000500747A (ja) * | 1995-11-13 | 2000-01-25 | スミスクライン・ビーチャム・コーポレイション | 血液調節化合物 |
EP1073640B1 (en) * | 1998-04-23 | 2005-04-13 | Takeda Pharmaceutical Company Limited | Naphthalene derivatives, their production and use |
JP4546589B2 (ja) * | 1998-04-23 | 2010-09-15 | 武田薬品工業株式会社 | ナフタレン誘導体 |
RU2363696C2 (ru) * | 2003-07-10 | 2009-08-10 | Оси Фармасьютикалз, Инк. | Производные нафтилена как ингибиторы цитохрома р450 |
US7662844B2 (en) * | 2004-07-12 | 2010-02-16 | Osi Pharmaceuticals, Inc. | Naphthylene derivatives as cytochrome P450 inhibitors |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GR75101B (es) * | 1980-10-23 | 1984-07-13 | Pfizer | |
ZA825413B (en) * | 1981-08-26 | 1983-06-29 | Pfizer | Thromboxane synthetase inhibitors, processes for their production, and pharmaceutical compositions comprising them |
-
1985
- 1985-03-13 DE DE19853508903 patent/DE3508903A1/de not_active Withdrawn
-
1986
- 1986-03-05 EP EP86102932A patent/EP0194579B1/de not_active Expired - Lifetime
- 1986-03-05 AT AT86102932T patent/ATE62226T1/de not_active IP Right Cessation
- 1986-03-05 DE DE8686102932T patent/DE3678470D1/de not_active Expired - Fee Related
- 1986-03-11 US US06/838,547 patent/US4734406A/en not_active Expired - Fee Related
- 1986-03-11 ES ES552871A patent/ES8800156A1/es not_active Expired
- 1986-03-12 PT PT82175A patent/PT82175B/pt not_active IP Right Cessation
- 1986-03-12 GR GR860679A patent/GR860679B/el unknown
- 1986-03-12 DK DK114286A patent/DK114286A/da not_active Application Discontinuation
- 1986-03-12 JP JP61052749A patent/JPS61227568A/ja active Pending
-
1987
- 1987-07-31 ES ES557647A patent/ES8801633A1/es not_active Expired
Also Published As
Publication number | Publication date |
---|---|
DE3678470D1 (de) | 1991-05-08 |
ES557647A0 (es) | 1988-02-16 |
DK114286A (da) | 1986-09-14 |
GR860679B (en) | 1986-07-14 |
PT82175A (de) | 1986-04-01 |
ES552871A0 (es) | 1987-11-01 |
ATE62226T1 (de) | 1991-04-15 |
DK114286D0 (da) | 1986-03-12 |
EP0194579A2 (de) | 1986-09-17 |
DE3508903A1 (de) | 1986-09-18 |
JPS61227568A (ja) | 1986-10-09 |
EP0194579A3 (en) | 1987-09-30 |
US4734406A (en) | 1988-03-29 |
EP0194579B1 (de) | 1991-04-03 |
ES8801633A1 (es) | 1988-02-16 |
PT82175B (pt) | 1988-07-29 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FD1A | Patent lapsed |
Effective date: 19970303 |