ES8102561A1 - Procedimiento de preparacion de los aril-1 arilsulfonil-4 a amino-propoxi-3 1h pirazoles - Google Patents

Procedimiento de preparacion de los aril-1 arilsulfonil-4 a amino-propoxi-3 1h pirazoles

Info

Publication number
ES8102561A1
ES8102561A1 ES492986A ES492986A ES8102561A1 ES 8102561 A1 ES8102561 A1 ES 8102561A1 ES 492986 A ES492986 A ES 492986A ES 492986 A ES492986 A ES 492986A ES 8102561 A1 ES8102561 A1 ES 8102561A1
Authority
ES
Spain
Prior art keywords
hypocholesterolemiant
hypolipemiant
arylsulphonyl
aminopropoxy
pyrazoles
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES492986A
Other languages
English (en)
Other versions
ES492986A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Laboratoire Roger Bellon SA
Original Assignee
Laboratoire Roger Bellon SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Laboratoire Roger Bellon SA filed Critical Laboratoire Roger Bellon SA
Publication of ES8102561A1 publication Critical patent/ES8102561A1/es
Publication of ES492986A0 publication Critical patent/ES492986A0/es
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/14—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D231/28—Two oxygen or sulfur atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics

Abstract

PROCEDIMIENTO DE PREPARACION DE LOS ARIL-1 ARILSULFONIL-4 AMINO-PROPOXI-3 1H PIRAZOLES, DE FORMULA (I), EN DONDE R1, R2, R3, R4, R5 Y R6 REPRESENTAN DISTINTOS ATOMOS O RADICALES. SE CARACTERIZA POR TENER LUGAR LA CONDENSACION DE UN HALOGENO-1 DIALKIL-AMINO-3 PROPANO X-(CH2)3-NR5R6, DONDE X ES UN ATOMO DE HALOGENO, CON UNA SAL ALCALINA DE UN ARIL-1-ARILSULFONIL-4 1H-PIRAZOLOIL-3, A UNA TEMPERATURA DE 60 A 120GC, EN EL SENO DE UN DISOLVENTE ORGANICO. TIENE APLICACIONES TERAPEUTICAS. -
ES492986A 1979-07-05 1980-07-01 Procedimiento de preparacion de los aril-1 arilsulfonil-4 a amino-propoxi-3 1h pirazoles Granted ES492986A0 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR7917507A FR2460299A1 (fr) 1979-07-05 1979-07-05 Nouveaux derives du pyrazole et leur application therapeutique

Publications (2)

Publication Number Publication Date
ES8102561A1 true ES8102561A1 (es) 1981-02-16
ES492986A0 ES492986A0 (es) 1981-02-16

Family

ID=9227565

Family Applications (1)

Application Number Title Priority Date Filing Date
ES492986A Granted ES492986A0 (es) 1979-07-05 1980-07-01 Procedimiento de preparacion de los aril-1 arilsulfonil-4 a amino-propoxi-3 1h pirazoles

Country Status (10)

Country Link
US (1) US4337263A (es)
JP (1) JPS5615271A (es)
BE (1) BE884189A (es)
CA (1) CA1152507A (es)
DE (1) DE3025579A1 (es)
ES (1) ES492986A0 (es)
FR (1) FR2460299A1 (es)
GB (2) GB2054566B (es)
IT (1) IT8068062A0 (es)
NL (1) NL8003888A (es)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ZA857592B (en) * 1984-10-17 1986-05-28 Heumann Ludwig & Co Gmbh Pyrazole derivatives,processes for their preparation and pharmaceutical preparations containing these compounds
US4964895A (en) * 1987-06-08 1990-10-23 Monsanto Company Substituted 4-(4-nitrophenoxy) pyrazoles and their use as herbicides
US6103900A (en) 1992-12-17 2000-08-15 Pfizer Inc Pyrazoles and pyrazolopyrimidines having CRF antagonistic activity
US6005109A (en) * 1997-10-30 1999-12-21 Pflizer Inc. Pyrazoles and pyrazolopyrimidines having CRF antagonistic activity
KR0170567B1 (ko) * 1992-12-17 1999-02-18 알렌 제이. 스피겔 부신피질자극호르몬-유리 인자 길항물질 활성을 갖는 피라졸 및 피라졸로피리미딘
US5646152A (en) * 1994-06-15 1997-07-08 Pfizer Inc. Methods of administering CRF antagonists
MX2007002341A (es) * 2004-08-27 2007-09-25 Esteve Labor Dr Inhibidores del receptor sigma.
EP1634872A1 (en) * 2004-08-27 2006-03-15 Laboratorios Del Dr. Esteve, S.A. Pyrazole derivatives as sigma receptor inhibitors
PL1781618T3 (pl) 2004-08-27 2013-03-29 Esteve Labor Dr Inhibitory receptora sigma
JP2009528315A (ja) * 2006-03-01 2009-08-06 ラボラトリオス・デル・ドクトル・エステベ・ソシエダッド・アノニマ シグマ受容体阻害剤としてのピラゾール誘導体
EP1829875A1 (en) 2006-03-01 2007-09-05 Laboratorios Del Dr. Esteve, S.A. Pyrazole derivatives as sigma receptor inhibitors
EP1829866A1 (en) * 2006-03-02 2007-09-05 Laboratorios Del Dr. Esteve, S.A. Sigma receptor inhibitors
EP1829867A1 (en) 2006-03-03 2007-09-05 Laboratorios Del Dr. Esteve, S.A. Imidazole compounds having pharmaceutical activity towards the sigma receptor
WO2009029317A2 (en) 2007-06-08 2009-03-05 Georgia State University Research Foundation, Inc. Compositions for regulating or modulating quorum sensing in bacteria, methods of using the compounds, and methods of regulating or modulating quorum sensing in bacteria
EP2116539A1 (en) 2008-04-25 2009-11-11 Laboratorios Del. Dr. Esteve, S.A. 1-aryl-3-aminoalkoxy-pyrazoles as sigma ligands enhancing analgesic effects of opioids and attenuating the dependency thereof
EP2353591A1 (en) 2010-02-04 2011-08-10 Laboratorios Del. Dr. Esteve, S.A. Sigma ligands for potentiating the analgesic effect of opioids and opiates in post-operative pain and attenuating the dependency thereof
EP2388005A1 (en) 2010-05-21 2011-11-23 Laboratorios Del. Dr. Esteve, S.A. Sigma ligands for the prevention and/or treatment of emesis induced by chemotherapy or radiotherapy
EP2395003A1 (en) 2010-05-27 2011-12-14 Laboratorios Del. Dr. Esteve, S.A. Pyrazole compounds as sigma receptor inhibitors
EP2415471A1 (en) 2010-08-03 2012-02-08 Laboratorios Del. Dr. Esteve, S.A. Use of sigma ligands in opioid-induced hyperalgesia
EP2524694A1 (en) 2011-05-19 2012-11-21 Laboratorios Del. Dr. Esteve, S.A. Use of sigma ligands in diabetes type-2 associated pain
KR20160097366A (ko) 2013-12-17 2016-08-17 라보라토리오스 델 드라. 에스테브.에스.에이. 세로토닌-노르에피네프린 재흡수 억제제들(SNRIs) 및 시그마 리셉터 리간드들 조합

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FI34517A (fi) 1962-12-08 1964-10-10 Laeaeketehdas Orion Oy 5-pyratsolyylialkamiinieetterien valmistusmenetelmä
JPS4832112B1 (es) * 1969-10-03 1973-10-04
DE2409753A1 (de) * 1974-03-01 1975-09-11 Basf Ag Substituierte pyrazole
FR2301250A1 (fr) 1975-02-21 1976-09-17 Bellon Labor Sa Roger Nouveaux diaryl-1, 4o-aminoalcoxy-3 pyrazoles et leurs sels

Also Published As

Publication number Publication date
FR2460299B1 (es) 1983-01-14
CA1152507A (fr) 1983-08-23
GB2063870A (en) 1981-06-10
FR2460299A1 (fr) 1981-01-23
DE3025579A1 (de) 1981-01-15
GB2063870B (en) 1983-06-22
NL8003888A (nl) 1981-01-07
IT8068062A0 (it) 1980-07-04
GB2054566A (en) 1981-02-18
US4337263A (en) 1982-06-29
ES492986A0 (es) 1981-02-16
BE884189A (fr) 1981-01-05
GB2054566B (en) 1983-05-18
JPS5615271A (en) 1981-02-14

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