FR2301250A1 - Nouveaux diaryl-1, 4o-aminoalcoxy-3 pyrazoles et leurs sels - Google Patents
Nouveaux diaryl-1, 4o-aminoalcoxy-3 pyrazoles et leurs selsInfo
- Publication number
- FR2301250A1 FR2301250A1 FR7505524A FR7505524A FR2301250A1 FR 2301250 A1 FR2301250 A1 FR 2301250A1 FR 7505524 A FR7505524 A FR 7505524A FR 7505524 A FR7505524 A FR 7505524A FR 2301250 A1 FR2301250 A1 FR 2301250A1
- Authority
- FR
- France
- Prior art keywords
- pyrazoles
- antiinflammatories
- prepd
- diaryl
- analgesics
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
- C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
- C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D231/14—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D231/18—One oxygen or sulfur atom
- C07D231/20—One oxygen atom attached in position 3 or 5
- C07D231/22—One oxygen atom attached in position 3 or 5 with aryl radicals attached to ring nitrogen atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR7505524A FR2301250A1 (fr) | 1975-02-21 | 1975-02-21 | Nouveaux diaryl-1, 4o-aminoalcoxy-3 pyrazoles et leurs sels |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR7505524A FR2301250A1 (fr) | 1975-02-21 | 1975-02-21 | Nouveaux diaryl-1, 4o-aminoalcoxy-3 pyrazoles et leurs sels |
Publications (2)
Publication Number | Publication Date |
---|---|
FR2301250A1 true FR2301250A1 (fr) | 1976-09-17 |
FR2301250B1 FR2301250B1 (fr) | 1979-06-29 |
Family
ID=9151572
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
FR7505524A Granted FR2301250A1 (fr) | 1975-02-21 | 1975-02-21 | Nouveaux diaryl-1, 4o-aminoalcoxy-3 pyrazoles et leurs sels |
Country Status (1)
Country | Link |
---|---|
FR (1) | FR2301250A1 (fr) |
Cited By (22)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2000027394A1 (fr) * | 1998-11-05 | 2000-05-18 | University College London | Activateurs de guanylate cyclase soluble |
WO2001007413A1 (fr) * | 1999-07-22 | 2001-02-01 | 3-Dimensional Pharmaceuticals, Inc. | 1-aryle-3-thioalkyle pyrazoles, leur synthese et leur utilisation comme insecticides |
US6409988B1 (en) | 1999-07-01 | 2002-06-25 | 3-Dimensional Pharmaceuticals, Inc. | Radiolabeled 1-aryl pyrazoles, the synthesis thereof and the use thereof as pest GABA receptor ligands |
US6506784B1 (en) | 1999-07-01 | 2003-01-14 | 3-Dimensional Pharmaceuticals, Inc. | Use of 1,3-substituted pyrazol-5-yl sulfonates as pesticides |
US6545033B1 (en) | 1999-10-06 | 2003-04-08 | 3-Dimensional Pharmaceuticals, Inc. | Fused 1-(2,6-dichloro-4-trifluoromethylphenyl)-pyrazoles, the synthesis thereof and the use thereof as pesticides |
US6562817B1 (en) | 1998-01-28 | 2003-05-13 | Shionogi & Co., Ltd. | Tricyclic compound |
WO2006021462A1 (fr) * | 2004-08-27 | 2006-03-02 | Laboratorios Del Dr. Esteve, S.A. | Inhibiteurs de récepteur sigma |
EP1634872A1 (fr) * | 2004-08-27 | 2006-03-15 | Laboratorios Del Dr. Esteve, S.A. | Dérivés de pyrazole en tant qu'inhibiteurs des récepteurs sigma |
EP1829875A1 (fr) | 2006-03-01 | 2007-09-05 | Laboratorios Del Dr. Esteve, S.A. | Dérivés de pyrazole comme inhibiteurs de récepteur Sigma |
EP1829867A1 (fr) | 2006-03-03 | 2007-09-05 | Laboratorios Del Dr. Esteve, S.A. | Composés d'imidazole ayant une acitivité pharmaceutique vis-à-vis le recepteur sigma |
EP1829866A1 (fr) | 2006-03-02 | 2007-09-05 | Laboratorios Del Dr. Esteve, S.A. | Inhibiteurs des récepteurs sigma |
JP2009528315A (ja) * | 2006-03-01 | 2009-08-06 | ラボラトリオス・デル・ドクトル・エステベ・ソシエダッド・アノニマ | シグマ受容体阻害剤としてのピラゾール誘導体 |
WO2011147910A1 (fr) | 2010-05-27 | 2011-12-01 | Laboratorios Del Dr. Esteve, S.A. | Composés pyrazole comme inhibiteurs du récepteur sigma |
US8293740B2 (en) | 2004-08-27 | 2012-10-23 | Laboratories Del Dr. Esteve, S.A. | Sigma receptor inhibitors |
JP2013501754A (ja) * | 2009-08-14 | 2013-01-17 | ラボラトリオス・デル・ドクター・エステベ・ソシエテ・アノニム | 化学療法によって誘発された疼痛を予防しまたは治療するためのσリガンド |
US9757358B2 (en) | 2010-02-04 | 2017-09-12 | Laboratorios Del Dr. Esteve, S.A. | Sigma ligands for potentiating the analgesic effect of opioids and opiates in post-operative pain and attenuating the dependency thereof |
US9782483B2 (en) | 2010-05-21 | 2017-10-10 | Laboratories Del Dr. Esteve, S.A. | Sigma ligands for the prevention and/or treatment of emesis induced by chemotherapy or radiotherapy |
US9789117B2 (en) | 2011-05-18 | 2017-10-17 | Laboratorios Del Dr. Esteve, S.A. | Use of sigma ligands in diabetes type-2 associated pain |
US9789115B2 (en) | 2010-08-03 | 2017-10-17 | Laboratorios Del Dr. Esteve, S.A. | Use of sigma ligands in opioid-induced hyperalgesia |
US9844516B2 (en) | 2010-02-04 | 2017-12-19 | Laboratorios De Dr. Esteve | Sigma ligands for use in the prevention and/or treatment of post-operative pain |
US9914705B2 (en) | 2008-04-25 | 2018-03-13 | Laboratorios Del Dr. Esteve, S.A. | 1-aryl-3-aminoalkoxy pyrazoles as sigma ligands enhancing analgesic effect of opioids and attenuating the dependency thereof |
US9931346B2 (en) | 2013-12-17 | 2018-04-03 | Laboratorios Del Dr. Esteve S.A. | Serotonin-norepinephrine reuptake inhibitors (SNRIs) and Sigma receptor ligands combinations |
Families Citing this family (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2460299A1 (fr) | 1979-07-05 | 1981-01-23 | Bellon Labor Sa Roger | Nouveaux derives du pyrazole et leur application therapeutique |
Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3149115A (en) * | 1962-11-02 | 1964-09-15 | American Cyanamid Co | Pyrazolinones and method of preparing the same |
GB1088973A (en) * | 1965-03-13 | 1967-10-25 | Acraf | Indazole derivatives |
-
1975
- 1975-02-21 FR FR7505524A patent/FR2301250A1/fr active Granted
Patent Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3149115A (en) * | 1962-11-02 | 1964-09-15 | American Cyanamid Co | Pyrazolinones and method of preparing the same |
GB1088973A (en) * | 1965-03-13 | 1967-10-25 | Acraf | Indazole derivatives |
Cited By (32)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6562817B1 (en) | 1998-01-28 | 2003-05-13 | Shionogi & Co., Ltd. | Tricyclic compound |
WO2000027394A1 (fr) * | 1998-11-05 | 2000-05-18 | University College London | Activateurs de guanylate cyclase soluble |
US6409988B1 (en) | 1999-07-01 | 2002-06-25 | 3-Dimensional Pharmaceuticals, Inc. | Radiolabeled 1-aryl pyrazoles, the synthesis thereof and the use thereof as pest GABA receptor ligands |
US6506784B1 (en) | 1999-07-01 | 2003-01-14 | 3-Dimensional Pharmaceuticals, Inc. | Use of 1,3-substituted pyrazol-5-yl sulfonates as pesticides |
WO2001007413A1 (fr) * | 1999-07-22 | 2001-02-01 | 3-Dimensional Pharmaceuticals, Inc. | 1-aryle-3-thioalkyle pyrazoles, leur synthese et leur utilisation comme insecticides |
US6518266B1 (en) | 1999-07-22 | 2003-02-11 | 3-Dimensional Pharmaceuticals | 1- Aryl-3-thioalkyl pyrazoles, the synthesis thereof and the use thereof as insecticides |
US6545033B1 (en) | 1999-10-06 | 2003-04-08 | 3-Dimensional Pharmaceuticals, Inc. | Fused 1-(2,6-dichloro-4-trifluoromethylphenyl)-pyrazoles, the synthesis thereof and the use thereof as pesticides |
EP2325174A1 (fr) | 2004-08-27 | 2011-05-25 | Laboratorios Del. Dr. Esteve, S.A. | Inhibiteurs de recepteur sigma |
US7696199B2 (en) | 2004-08-27 | 2010-04-13 | Laboratorios Del Dr. Esteve, S.A. | Sigma receptor inhibitors |
US8470867B2 (en) | 2004-08-27 | 2013-06-25 | Laboratorios Del Dr. Esteve, S.A. | Sigma receptor inhibitors |
US8314096B2 (en) | 2004-08-27 | 2012-11-20 | Laboratorios Del Dr. Esteve, S.A. | Sigma receptor inhibitors |
US8293740B2 (en) | 2004-08-27 | 2012-10-23 | Laboratories Del Dr. Esteve, S.A. | Sigma receptor inhibitors |
WO2006021462A1 (fr) * | 2004-08-27 | 2006-03-02 | Laboratorios Del Dr. Esteve, S.A. | Inhibiteurs de récepteur sigma |
JP2008510767A (ja) * | 2004-08-27 | 2008-04-10 | ラボラトリオス デル ドクトール エステベ エセ.ア. | シグマ受容体阻害剤 |
EP1634872A1 (fr) * | 2004-08-27 | 2006-03-15 | Laboratorios Del Dr. Esteve, S.A. | Dérivés de pyrazole en tant qu'inhibiteurs des récepteurs sigma |
JP2009528315A (ja) * | 2006-03-01 | 2009-08-06 | ラボラトリオス・デル・ドクトル・エステベ・ソシエダッド・アノニマ | シグマ受容体阻害剤としてのピラゾール誘導体 |
EP1829875A1 (fr) | 2006-03-01 | 2007-09-05 | Laboratorios Del Dr. Esteve, S.A. | Dérivés de pyrazole comme inhibiteurs de récepteur Sigma |
US8088812B2 (en) | 2006-03-02 | 2012-01-03 | Laboratorios Del Dr. Esteve, S.A. | Sigma receptor inhibitors |
EP1829866A1 (fr) | 2006-03-02 | 2007-09-05 | Laboratorios Del Dr. Esteve, S.A. | Inhibiteurs des récepteurs sigma |
WO2007098963A1 (fr) * | 2006-03-02 | 2007-09-07 | Laboratorios Del Dr. Esteve S.A. | Inhibiteurs du recepteur sigma |
EP1829867A1 (fr) | 2006-03-03 | 2007-09-05 | Laboratorios Del Dr. Esteve, S.A. | Composés d'imidazole ayant une acitivité pharmaceutique vis-à-vis le recepteur sigma |
US9914705B2 (en) | 2008-04-25 | 2018-03-13 | Laboratorios Del Dr. Esteve, S.A. | 1-aryl-3-aminoalkoxy pyrazoles as sigma ligands enhancing analgesic effect of opioids and attenuating the dependency thereof |
JP2013501754A (ja) * | 2009-08-14 | 2013-01-17 | ラボラトリオス・デル・ドクター・エステベ・ソシエテ・アノニム | 化学療法によって誘発された疼痛を予防しまたは治療するためのσリガンド |
US9844516B2 (en) | 2010-02-04 | 2017-12-19 | Laboratorios De Dr. Esteve | Sigma ligands for use in the prevention and/or treatment of post-operative pain |
US9757358B2 (en) | 2010-02-04 | 2017-09-12 | Laboratorios Del Dr. Esteve, S.A. | Sigma ligands for potentiating the analgesic effect of opioids and opiates in post-operative pain and attenuating the dependency thereof |
US9782483B2 (en) | 2010-05-21 | 2017-10-10 | Laboratories Del Dr. Esteve, S.A. | Sigma ligands for the prevention and/or treatment of emesis induced by chemotherapy or radiotherapy |
US9181195B2 (en) | 2010-05-27 | 2015-11-10 | Laboratorios Del Dr. Esteve, S.A. | Sigma receptor inhibitors |
EP2395003A1 (fr) | 2010-05-27 | 2011-12-14 | Laboratorios Del. Dr. Esteve, S.A. | Composés pyrazoliques en tant qu'inhibiteurs du récepteur sigma |
WO2011147910A1 (fr) | 2010-05-27 | 2011-12-01 | Laboratorios Del Dr. Esteve, S.A. | Composés pyrazole comme inhibiteurs du récepteur sigma |
US9789115B2 (en) | 2010-08-03 | 2017-10-17 | Laboratorios Del Dr. Esteve, S.A. | Use of sigma ligands in opioid-induced hyperalgesia |
US9789117B2 (en) | 2011-05-18 | 2017-10-17 | Laboratorios Del Dr. Esteve, S.A. | Use of sigma ligands in diabetes type-2 associated pain |
US9931346B2 (en) | 2013-12-17 | 2018-04-03 | Laboratorios Del Dr. Esteve S.A. | Serotonin-norepinephrine reuptake inhibitors (SNRIs) and Sigma receptor ligands combinations |
Also Published As
Publication number | Publication date |
---|---|
FR2301250B1 (fr) | 1979-06-29 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
ST | Notification of lapse |