ES8705401A1 - Un procedimiento para la obtencion de 1.4-dihidropirazinas - Google Patents

Un procedimiento para la obtencion de 1.4-dihidropirazinas

Info

Publication number
ES8705401A1
ES8705401A1 ES550974A ES550974A ES8705401A1 ES 8705401 A1 ES8705401 A1 ES 8705401A1 ES 550974 A ES550974 A ES 550974A ES 550974 A ES550974 A ES 550974A ES 8705401 A1 ES8705401 A1 ES 8705401A1
Authority
ES
Spain
Prior art keywords
dihydropyrazines
medicines
preparation
circulation
formula
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES550974A
Other languages
English (en)
Other versions
ES550974A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bayer AG
Original Assignee
Bayer AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer AG filed Critical Bayer AG
Publication of ES550974A0 publication Critical patent/ES550974A0/es
Publication of ES8705401A1 publication Critical patent/ES8705401A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D241/00—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
    • C07D241/02—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D241/00—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
    • C07D241/02—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings
    • C07D241/06—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having one or two double bonds between ring members or between ring members and non-ring members
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Cardiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)

Abstract

PROCEDIMIENTO PARA LA OBTENCION DE DERIVADOS DE 4-DIHIDROPIRAZINAS, DE FORMULA (I). COMPRENDE LA REACCION DE UNA AMINA PRIMARIA, DE FORMULA RNH2 CON UN COMPUESTO AZO-EN-CARBONILICO, DE FORMULA (II), EN UN DISOLVENTE ORGANICO INERTE, A UNA TEMPERATURA COMPRENDIDA ENTRE 20JC Y 150JC, PARA OBTENER EL COMPUESTO DE FORMULA (I), EN LA QUE X REPRESENTA CARBAMOILO O ALCOXICARBONILO, Y R, R1 Y R2 PUEDEN SER VARIOS TIPOS DE RADICALES. ESTOS COMPUESTOS TIENEN APLICACIONES FARMACOLOGICAS PARA EL TRATAMIENTO DE ENFERMEDADES CIRUCLATORIAS.
ES550974A 1984-01-12 1986-01-16 Un procedimiento para la obtencion de 1.4-dihidropirazinas Expired ES8705401A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19843400765 DE3400765A1 (de) 1984-01-12 1984-01-12 1.4-dihydropyrazine, verfahren zu ihrer herstellung sowie ihre verwendung in arzneimitteln

Publications (2)

Publication Number Publication Date
ES550974A0 ES550974A0 (es) 1987-05-01
ES8705401A1 true ES8705401A1 (es) 1987-05-01

Family

ID=6224714

Family Applications (2)

Application Number Title Priority Date Filing Date
ES539424A Expired ES8606298A1 (es) 1984-01-12 1985-01-09 1.4-dihidropirazinas
ES550974A Expired ES8705401A1 (es) 1984-01-12 1986-01-16 Un procedimiento para la obtencion de 1.4-dihidropirazinas

Family Applications Before (1)

Application Number Title Priority Date Filing Date
ES539424A Expired ES8606298A1 (es) 1984-01-12 1985-01-09 1.4-dihidropirazinas

Country Status (7)

Country Link
EP (1) EP0149237A3 (es)
JP (1) JPS60158183A (es)
KR (1) KR850005419A (es)
DE (1) DE3400765A1 (es)
DK (1) DK14885A (es)
ES (2) ES8606298A1 (es)
HU (1) HUT37764A (es)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HUT39179A (en) * 1984-12-10 1986-08-28 Sandoz Ag Process for production of derivatives of 1,4-dihydro-piridin

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4307103A (en) * 1978-09-08 1981-12-22 Fujisawa Pharmaceutical Co., Ltd. Dihydropyridine derivative, processes for preparation thereof and pharmaceutical composition comprising the same

Also Published As

Publication number Publication date
EP0149237A2 (de) 1985-07-24
ES539424A0 (es) 1986-04-16
ES550974A0 (es) 1987-05-01
DK14885A (da) 1985-07-13
HUT37764A (en) 1986-02-28
DE3400765A1 (de) 1985-07-18
DK14885D0 (da) 1985-01-11
JPS60158183A (ja) 1985-08-19
EP0149237A3 (de) 1986-05-14
ES8606298A1 (es) 1986-04-16
KR850005419A (ko) 1985-08-26

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