ES8609305A1 - Piridiletil-dihidropiridinas - Google Patents

Piridiletil-dihidropiridinas

Info

Publication number
ES8609305A1
ES8609305A1 ES546705A ES546705A ES8609305A1 ES 8609305 A1 ES8609305 A1 ES 8609305A1 ES 546705 A ES546705 A ES 546705A ES 546705 A ES546705 A ES 546705A ES 8609305 A1 ES8609305 A1 ES 8609305A1
Authority
ES
Spain
Prior art keywords
medicaments
pyridylethyl
dihydropyridines
preparation
pyridylethyldihydropyridines
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES546705A
Other languages
English (en)
Other versions
ES546705A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bayer AG
Original Assignee
Bayer AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer AG filed Critical Bayer AG
Publication of ES546705A0 publication Critical patent/ES546705A0/es
Publication of ES8609305A1 publication Critical patent/ES8609305A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/80—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D211/84—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen directly attached to ring carbon atoms
    • C07D211/90—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Vascular Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Pyridine Compounds (AREA)

Abstract

PROCEDIMIENTO PARA LA OBTENCION DE PIRI-DILETIL-DIHIDROPIRIDINA, DE FORMULA (I). COMPRENDE LA REACCION DE ENAMINAS, DE FORMULA (II) CON CETOCOMPUESTOS, DE FORMULA R3-COCH2-Y, Y CON EL ALDEHIDO, DE FORMULA (III), PARA FORMAR EL COMPUESTO DE FORMULA (I), EN LAS QUE X, Y, R1, R2 Y R3 PUEDEN SER DIVERSOS RADICALES. LA REACCION SE LLEVA A CABO EN UN DISOLVENTE ORGANICO INERTE A UNA TEMPERATURA COMPRENDIDA ENTRE 10JC Y 150JC, Y, EVENTUALMENTE, LOS GRUPOS ALCOXICARBONILO DEL COMPUESTO DE FORMULA (I) SE SAPONIFICAN Y DESCARBOXILAN EN MEDIO ACIDO. ESTOS COMPUESTOS TIENEN APLICACIONES FARMACOLOGICAS PARA EL TRATAMIENTO DE ENFERMEDADES TROMBOEMBOLICAS E ISQUEMICAS.
ES546705A 1984-09-05 1985-09-04 Piridiletil-dihidropiridinas Expired ES8609305A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19843432563 DE3432563A1 (de) 1984-09-05 1984-09-05 Neue pyridylethyl-dihydropyridine, verfahren zu ihrer herstellung und ihre verwendung in arzneimittel

Publications (2)

Publication Number Publication Date
ES546705A0 ES546705A0 (es) 1986-09-01
ES8609305A1 true ES8609305A1 (es) 1986-09-01

Family

ID=6244652

Family Applications (2)

Application Number Title Priority Date Filing Date
ES546705A Expired ES8609305A1 (es) 1984-09-05 1985-09-04 Piridiletil-dihidropiridinas
ES554606A Expired ES8802309A1 (es) 1984-09-05 1986-04-30 Procedimiento para la obtencion de piridiletil-dihidropiridinas

Family Applications After (1)

Application Number Title Priority Date Filing Date
ES554606A Expired ES8802309A1 (es) 1984-09-05 1986-04-30 Procedimiento para la obtencion de piridiletil-dihidropiridinas

Country Status (4)

Country Link
EP (1) EP0173943A1 (es)
JP (1) JPS6168488A (es)
DE (1) DE3432563A1 (es)
ES (2) ES8609305A1 (es)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5430044A (en) * 1987-02-06 1995-07-04 Fisons Corporation Arylalkyl-amines and -amides having anticonvulsant and neuroprotective properties
US5843950A (en) * 1994-07-29 1998-12-01 Nikken Chemicals Co., Ltd. 1,4-dihydropyridine compound and pharmaceutical composition containing the same
KR20010020267A (ko) * 1997-04-25 2001-03-15 에가시라 구니오 신규한 디하이드로피리딘 유도체
AU6229099A (en) * 1998-10-23 2000-05-15 Ajinomoto Co., Inc. Dihydropyridine derivatives and drug compositions containing the same
US11970478B1 (en) 2023-11-16 2024-04-30 King Faisal University 9-(2-hydroxyquinolin-3-yl)-10-(2-hydroxyethyl)-3,3,6,6-tetramethyl-3,4,6,7,9,10-hexahydroacridine1,8(2H,5H)-dione as an antimicrobial compound

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2005116C3 (de) * 1970-02-05 1980-02-14 Bayer Ag, 5090 Leverkusen Symmetrische 1,4-Dihydropyridin-3,5-dicarbonsäureester
DE2335466A1 (de) * 1973-07-12 1975-01-30 Bayer Ag Alkoxyalkyl-1,4-dihydropyridine, verfahren zu ihrer herstellung sowie ihre verwendung als arzneimittel

Also Published As

Publication number Publication date
EP0173943A1 (de) 1986-03-12
ES546705A0 (es) 1986-09-01
DE3432563A1 (de) 1986-03-13
ES554606A0 (es) 1987-04-16
JPS6168488A (ja) 1986-04-08
ES8802309A1 (es) 1987-04-16

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