ES8802309A1 - Procedimiento para la obtencion de piridiletil-dihidropiridinas - Google Patents

Procedimiento para la obtencion de piridiletil-dihidropiridinas

Info

Publication number
ES8802309A1
ES8802309A1 ES554606A ES554606A ES8802309A1 ES 8802309 A1 ES8802309 A1 ES 8802309A1 ES 554606 A ES554606 A ES 554606A ES 554606 A ES554606 A ES 554606A ES 8802309 A1 ES8802309 A1 ES 8802309A1
Authority
ES
Spain
Prior art keywords
medicaments
pyridylethyl
dihydropyridines
preparation
pyridylethyldihydropyridines
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES554606A
Other languages
English (en)
Other versions
ES554606A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bayer AG
Original Assignee
Bayer AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer AG filed Critical Bayer AG
Publication of ES8802309A1 publication Critical patent/ES8802309A1/es
Publication of ES554606A0 publication Critical patent/ES554606A0/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/80—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D211/84—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen directly attached to ring carbon atoms
    • C07D211/90—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Hematology (AREA)
  • Vascular Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Diabetes (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyridine Compounds (AREA)
  • Hydrogenated Pyridines (AREA)

Abstract

PROCEDIMIENTO PARA OBTENER PIRIDILETIL-DIHIDROPIRIDINAS. CONSISTE EN HACER REACCIONAR CETOCOMPUESTOS DE FORMULAS (II) O (III) CON ALDEHIDOS DE HALOGENO (IV) Y CON UNA AMINA DE FORMULA R1-NH2, EN ISOPROPANOL, Y ENTRE 10 Y 150JC, PARA OBTENER COMPUESTOS DE FORMULA (I) Y SUS SALES FISIOLOGICAMENTE ACEPTABLES, SIENDO: R1, H O ALQUILO DE CADENA LINEAL SUSTITUIDO POR HALOGENO, NITRO Y CIANO; R2 Y R3, H O ALQUILO DE CADENA LINEAL SUSTITUIDO POR HAL, ARILO Y OTROS; R4, H O ALQUILO DE CADENA LINEAL SUSTITUIDO POR HAL, NITRO Y OTROS; Y X E G, H, CIANO Y OTROS. TIENEN APLICACIONES FARMACEUTICAS POR SU ACTIVIDAD TROMBOEMBOLICA E ISQUEMICA.
ES554606A 1984-09-05 1986-04-30 Procedimiento para la obtencion de piridiletil-dihidropiridinas Expired ES8802309A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19843432563 DE3432563A1 (de) 1984-09-05 1984-09-05 Neue pyridylethyl-dihydropyridine, verfahren zu ihrer herstellung und ihre verwendung in arzneimittel

Publications (2)

Publication Number Publication Date
ES8802309A1 true ES8802309A1 (es) 1987-04-16
ES554606A0 ES554606A0 (es) 1987-04-16

Family

ID=6244652

Family Applications (2)

Application Number Title Priority Date Filing Date
ES546705A Expired ES8609305A1 (es) 1984-09-05 1985-09-04 Piridiletil-dihidropiridinas
ES554606A Expired ES8802309A1 (es) 1984-09-05 1986-04-30 Procedimiento para la obtencion de piridiletil-dihidropiridinas

Family Applications Before (1)

Application Number Title Priority Date Filing Date
ES546705A Expired ES8609305A1 (es) 1984-09-05 1985-09-04 Piridiletil-dihidropiridinas

Country Status (4)

Country Link
EP (1) EP0173943A1 (es)
JP (1) JPS6168488A (es)
DE (1) DE3432563A1 (es)
ES (2) ES8609305A1 (es)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5430044A (en) * 1987-02-06 1995-07-04 Fisons Corporation Arylalkyl-amines and -amides having anticonvulsant and neuroprotective properties
WO1996004268A1 (fr) * 1994-07-29 1996-02-15 Nikken Chemicals Co., Ltd. Compose de 1,4-dihydropyridine et composition medicinale contenant ledit compose
JP4332902B2 (ja) 1997-04-25 2009-09-16 味の素株式会社 新規ジヒドロピリジン誘導体
AU6229099A (en) * 1998-10-23 2000-05-15 Ajinomoto Co., Inc. Dihydropyridine derivatives and drug compositions containing the same
US11970478B1 (en) 2023-11-16 2024-04-30 King Faisal University 9-(2-hydroxyquinolin-3-yl)-10-(2-hydroxyethyl)-3,3,6,6-tetramethyl-3,4,6,7,9,10-hexahydroacridine1,8(2H,5H)-dione as an antimicrobial compound

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2005116C3 (de) * 1970-02-05 1980-02-14 Bayer Ag, 5090 Leverkusen Symmetrische 1,4-Dihydropyridin-3,5-dicarbonsäureester
DE2335466A1 (de) * 1973-07-12 1975-01-30 Bayer Ag Alkoxyalkyl-1,4-dihydropyridine, verfahren zu ihrer herstellung sowie ihre verwendung als arzneimittel

Also Published As

Publication number Publication date
ES8609305A1 (es) 1986-09-01
DE3432563A1 (de) 1986-03-13
JPS6168488A (ja) 1986-04-08
EP0173943A1 (de) 1986-03-12
ES546705A0 (es) 1986-09-01
ES554606A0 (es) 1987-04-16

Similar Documents

Publication Publication Date Title
AU584124B2 (en) Diarylacetylenes, their preparation and their use
ZA836592B (en) Quinoline derivatives and their use for controlling undesirable plant growth
ES8801277A1 (es) Procedimiento para preparar (1,2,4) triazolo (1,5-c) quinazolinas
AU1725188A (en) Pyridooxazinone-pyridone compounds, cardiotonic compositions including the same, and their uses
ES8607271A1 (es) Amidinohidrazonas
HUT39152A (en) Process for preparing 1-substituted tetraline-derivatives
EP0130633A3 (en) Process for the preparation of 1-(phenyl)-1-hydroxy-2-amino-3-fluoro propane derivatives
ES8200122A1 (es) Un metodo para la preparacion de 17,21-diesteres de 6alfa- 9alfa-didluoro-16-metil-prednisolona
DE3164474D1 (en) N-benzoyl n' phenylureas, preparation and use thereof as insecticides
CA2111083A1 (en) Novel peptides, their preparation and use
MY132057A (en) Quinoxalinones, a process for their preparation and their use
JPS6419066A (en) Dihydropyridineamides
ES8104287A1 (es) Un procedimiento para la preparacion de pirido (1,2-a) piri-midinas substituidas
HUT39962A (en) Herbicide compositions containing 2,4-diamino-pyrimidine derivatives as active ingredients and process for preparing the active ingredients
ES8802309A1 (es) Procedimiento para la obtencion de piridiletil-dihidropiridinas
IL73825A0 (en) Compositions containing an n,n'-alkylenediamide or and amidoalkylimidazole derivative and process for preparing the same
IL85189A (en) Beta-alkyl substituted melatonins,their preparation and pharmaceutical compositions containing them
BG98238A (en) Substituted benzothiazole derivatives, methods for their preparation and their application as herbicides
EP0234348A3 (en) N-glycosyl amide derivatives, method for their preparation and their use as medicaments
EP0717618A4 (en) STABILIZED FORMULATION FOR TABLETS
ZA823602B (en) N-substituted 2-methylnaphthylamides, their preparation, and their use for controlling fungi
AU1630288A (en) Substituted compounds, processes for their preparation and uses thereof
GR3001542T3 (en) Benzofuran carboxamides with basic substituents, process for their preparation and therapeutical compositions containing them
ES8400747A1 (es) "procedimiento para la preparacion de 2-mesitilimino-3-alcohil-3,4,6,7-tetrahidro-2h-pirimido(6,1-a)isoquinolein-4-onas sustituidas en 9,10".
ES8703847A1 (es) Procedimiento para la obtencion de derivados de sulfonilgua-nidinopirimidina