ES8104287A1 - Un procedimiento para la preparacion de pirido (1,2-a) piri-midinas substituidas - Google Patents

Un procedimiento para la preparacion de pirido (1,2-a) piri-midinas substituidas

Info

Publication number
ES8104287A1
ES8104287A1 ES491238A ES491238A ES8104287A1 ES 8104287 A1 ES8104287 A1 ES 8104287A1 ES 491238 A ES491238 A ES 491238A ES 491238 A ES491238 A ES 491238A ES 8104287 A1 ES8104287 A1 ES 8104287A1
Authority
ES
Spain
Prior art keywords
allergic
substituted
ulcer agents
pyrimidines useful
pyrido
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES491238A
Other languages
English (en)
Other versions
ES491238A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pfizer Italia SRL
Original Assignee
Farmitalia Carlo Erba SRL
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Farmitalia Carlo Erba SRL filed Critical Farmitalia Carlo Erba SRL
Publication of ES491238A0 publication Critical patent/ES491238A0/es
Publication of ES8104287A1 publication Critical patent/ES8104287A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Pulmonology (AREA)
  • Pain & Pain Management (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)

Abstract

PROCEDIMIENTO PARA LA PREPARACION DE PIRIDO (1,2-A) PIRIMIDINAS SUSTITUIDAS, DE FORMULA GENERAL (I), Y SUS SALES FARMACEUTICAMENTE ACEPTABLES, DONDE A, R1, R2 Y R3 REPRESENTAN DISTINTOS TIPOS DE RADICALES O ATOMOS. SE OBTIENEN HACIENDO REACCIONAR UN COMPUESTO DE FORMULA (II) CON UN ALDEHIDO DE FORMULA (III). ALTERNATIVAMENTE SE PUEDE OBTENER HACIENDO CICLOPROPANAR UN COMPUESTO DE FORMULA (IV) Y TAMBIEN SE PUEDE OBTENER POR ULTIMO HIDROLIZANDO UN COMPUESTO DE FORMULA (V), DONDE R REPRESENTA DISTINTOS RADICALES. ESTOS COMPUESTOS TIENEN APLICACIONES FARMACOLOGICAS. *FORMULA*
ES491238A 1979-05-08 1980-05-07 Un procedimiento para la preparacion de pirido (1,2-a) piri-midinas substituidas Expired ES8104287A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB7915810 1979-05-08

Publications (2)

Publication Number Publication Date
ES491238A0 ES491238A0 (es) 1981-04-01
ES8104287A1 true ES8104287A1 (es) 1981-04-01

Family

ID=10504995

Family Applications (1)

Application Number Title Priority Date Filing Date
ES491238A Expired ES8104287A1 (es) 1979-05-08 1980-05-07 Un procedimiento para la preparacion de pirido (1,2-a) piri-midinas substituidas

Country Status (28)

Country Link
US (2) US4310526A (es)
JP (1) JPS562983A (es)
AT (1) AT375370B (es)
AU (1) AU527931B2 (es)
BE (1) BE883150A (es)
CA (1) CA1134359A (es)
CH (1) CH647777A5 (es)
CS (2) CS528780A2 (es)
DE (1) DE3015738A1 (es)
DK (1) DK200280A (es)
ES (1) ES8104287A1 (es)
FI (1) FI68824C (es)
FR (1) FR2456093A1 (es)
GB (1) GB2050353B (es)
GR (1) GR68075B (es)
HU (1) HU181778B (es)
IE (1) IE49787B1 (es)
IL (1) IL59802A (es)
IT (1) IT1209326B (es)
LU (1) LU82419A1 (es)
NL (1) NL8002656A (es)
NO (1) NO153137C (es)
NZ (1) NZ193579A (es)
PH (1) PH16695A (es)
PT (1) PT71197A (es)
SE (1) SE437158B (es)
SU (2) SU1217259A3 (es)
ZA (1) ZA802390B (es)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AT377586B (de) 1981-06-30 1985-04-10 Erba Farmitalia Verfahren zur herstellung von substituierten pyrrolo-(2,1-b)-chinazolinen und pyrido(2,1-b)chinazolinen
US4537962A (en) * 1982-02-04 1985-08-27 Farmitalia Carlo Erba, S.P.A. Substituted 1,3,4-thiadiazolo[3,2-A]pyrimidines and compositions containing them
CA1211111A (en) * 1982-02-15 1986-09-09 Isao Yanagisawa Process for preparing novel pyrimidone compounds
ES8406476A1 (es) * 1982-04-29 1984-07-01 Erba Farmitalia Procedimiento para preparar derivados cicloalifaticos condensados de pirido(1,2-a)pirimidinas sustituidas.
IL69274A (en) * 1982-08-05 1986-08-31 Erba Farmitalia (substituted amino)derivatives of 3-benzylidene-pyrrolo(2,1-b)quinazolin-9-ones and 6-benzylidene-pyrido(2,1-b)quinazolin-11-ones,their preparation and pharmaceutical compositions containing them
GB8300728D0 (en) * 1983-01-12 1983-02-16 Erba Farmitalia Substituted carboxy-thiazolo / 3 2 - a / pyrimidine derivatives
US4457932A (en) * 1983-07-22 1984-07-03 Bristol-Myers Company Anti-ulcer agents
GB8501015D0 (en) * 1985-01-16 1985-02-20 Riker Laboratories Inc Drug
JP2668259B2 (ja) * 1988-02-18 1997-10-27 塩野義製薬株式会社 複素環化合物および抗潰瘍剤
JP5419894B2 (ja) * 2008-01-11 2014-02-19 グレンマーク ファーマシューティカルズ， エセ．アー． Ｔｒｐｖ３モジュレーターとしての縮合ピリミジン誘導体

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4209622A (en) * 1973-03-30 1980-06-24 Chinoin Gygyszer es Vegyeszeti Termekek Gyara Rt. 3-(Ethoxycarbonyl-methyl)-6-methyl-4-oxo-6,7,8,9-tetrahydro-4H-pyrido[1,2-a]pyrimidine
US3935197A (en) * 1975-05-16 1976-01-27 E. R. Squibb & Sons, Inc. 2-Styryl-4H-pyrido(1,2-a)pyrimidin-4-ones
HU178910B (en) 1977-08-19 1982-07-28 Chinoin Gyogyszer Es Vegyeszet Process for preparing 2,3-disubstituted-4-oxo-4h-pyrido/1,2-a/-pyrimidines
HU180701B (en) 1977-12-29 1983-04-29 Chinoin Gyogyszer Es Vegyeszet Process for preparing pyrido-/1,2-a/pyrimidines containing a carboxylic or ester group on the pirimidimering
HU184058B (en) 1977-12-29 1984-06-28 Chinoin Gyogyszer Es Vegyeszet Process for preparing new compounds with nitrogen bridge head

Also Published As

Publication number Publication date
GR68075B (es) 1981-10-30
IT1209326B (it) 1989-07-16
IE49787B1 (en) 1985-12-11
SE8003433L (sv) 1980-11-09
ES491238A0 (es) 1981-04-01
DK200280A (da) 1980-11-09
NO153137B (no) 1985-10-14
NL8002656A (nl) 1980-11-11
IE800945L (en) 1980-11-08
SE437158B (sv) 1985-02-11
GB2050353B (en) 1983-04-27
LU82419A1 (fr) 1980-07-31
FR2456093B1 (es) 1984-02-03
DE3015738A1 (de) 1980-11-13
US4310526A (en) 1982-01-12
FR2456093A1 (fr) 1980-12-05
FI68824C (fi) 1985-11-11
FI68824B (fi) 1985-07-31
SU1217259A3 (ru) 1986-03-07
NO801342L (no) 1980-11-10
BE883150A (fr) 1980-11-07
AT375370B (de) 1984-07-25
CS321380A2 (en) 1984-12-14
JPS562983A (en) 1981-01-13
NO153137C (no) 1986-01-22
CS244107B2 (en) 1986-07-17
US4341780A (en) 1982-07-27
IT8021821A0 (it) 1980-05-06
AU527931B2 (en) 1983-03-31
PT71197A (en) 1980-06-01
HU181778B (en) 1983-11-28
ZA802390B (en) 1981-04-29
IL59802A0 (en) 1980-06-30
SU1158045A3 (ru) 1985-05-23
PH16695A (en) 1984-01-06
CH647777A5 (de) 1985-02-15
CA1134359A (en) 1982-10-26
ATA245680A (de) 1983-12-15
CS528780A2 (en) 1985-09-17
IL59802A (en) 1983-07-31
FI801464A (fi) 1980-11-09
GB2050353A (en) 1981-01-07
NZ193579A (en) 1982-09-07
AU5731980A (en) 1980-11-13

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