FR23C1040I1 - Combinaison comprenant un cristal stable d'un composé 4-oxoquinoline - Google Patents

Combinaison comprenant un cristal stable d'un composé 4-oxoquinoline

Info

Publication number
FR23C1040I1
FR23C1040I1 FR23C1040C FR23C1040C FR23C1040I1 FR 23C1040 I1 FR23C1040 I1 FR 23C1040I1 FR 23C1040 C FR23C1040 C FR 23C1040C FR 23C1040 C FR23C1040 C FR 23C1040C FR 23C1040 I1 FR23C1040 I1 FR 23C1040I1
Authority
FR
France
Prior art keywords
combination
stable crystal
oxoquinoline compound
oxoquinoline
compound
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
FR23C1040C
Other languages
English (en)
French (fr)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Japan Tobacco Inc
Original Assignee
Japan Tobacco Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=35079161&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=FR23C1040(I1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Japan Tobacco Inc filed Critical Japan Tobacco Inc
Publication of FR23C1040I1 publication Critical patent/FR23C1040I1/fr
Active legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/48—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • C07D215/54—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 3
    • C07D215/56—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 3 with oxygen atoms in position 4
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Virology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Molecular Biology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • AIDS & HIV (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Quinoline Compounds (AREA)
FR23C1040C 2004-05-20 2023-11-02 Combinaison comprenant un cristal stable d'un composé 4-oxoquinoline Active FR23C1040I1 (fr)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
JP2004150979 2004-05-20
EP05726243A EP1636190B1 (en) 2004-05-20 2005-05-19 Stable crystal of 4-oxoquinoline compound
PCT/JP2005/009604 WO2005113508A1 (en) 2004-05-20 2005-05-19 Stable crystal of 4-oxoquinoline compound
EP12173572A EP2514746A1 (en) 2004-05-20 2005-05-19 Stable crystal of 4-oxoquinoline compound

Publications (1)

Publication Number Publication Date
FR23C1040I1 true FR23C1040I1 (fr) 2023-12-29

Family

ID=35079161

Family Applications (1)

Application Number Title Priority Date Filing Date
FR23C1040C Active FR23C1040I1 (fr) 2004-05-20 2023-11-02 Combinaison comprenant un cristal stable d'un composé 4-oxoquinoline

Country Status (33)

Country Link
US (7) US7635704B2 (pm)
EP (4) EP3281939B1 (pm)
JP (1) JP3754064B2 (pm)
KR (1) KR20080064909A (pm)
CN (1) CN1956961B (pm)
AR (2) AR049280A1 (pm)
AU (1) AU2005245296B2 (pm)
BE (1) BE2024C511I2 (pm)
BR (1) BRPI0510114B8 (pm)
CA (1) CA2566922C (pm)
CY (4) CY1113010T1 (pm)
DK (2) DK1636190T3 (pm)
ES (2) ES2388441T3 (pm)
FI (2) FI3281939T3 (pm)
FR (1) FR23C1040I1 (pm)
HR (2) HRP20120681T1 (pm)
HU (2) HUE064615T2 (pm)
IL (1) IL179250A0 (pm)
LT (2) LT3281939T (pm)
LU (1) LUC00334I2 (pm)
MX (1) MXPA06013405A (pm)
MY (1) MY134672A (pm)
NO (8) NO339223B1 (pm)
NZ (1) NZ551839A (pm)
PE (2) PE20060358A1 (pm)
PL (2) PL1636190T3 (pm)
PT (2) PT1636190E (pm)
RS (2) RS52375B (pm)
RU (1) RU2330845C1 (pm)
SI (2) SI1636190T1 (pm)
TW (1) TWI329015B (pm)
WO (1) WO2005113508A1 (pm)
ZA (1) ZA200610647B (pm)

Families Citing this family (37)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6891227B2 (en) 2002-03-20 2005-05-10 International Business Machines Corporation Self-aligned nanotube field effect transistor and method of fabricating same
DK1564210T5 (da) * 2002-11-20 2010-05-03 Japan Tobacco Inc 4-Oxoquinolinforbindelser og anvendelse deraf som HIV-integraseinhibitorer
MY134672A (en) * 2004-05-20 2007-12-31 Japan Tobacco Inc Stable crystal of 4-oxoquinoline compound
WO2007063869A1 (ja) * 2005-11-30 2007-06-07 Japan Tobacco Inc. 高純度キノロン化合物の製造方法
SG170796A1 (en) * 2005-12-30 2011-05-30 Gilead Sciences Inc Us Methods for improving the pharmacokinetics of hiv integrase inhibitors
US20090233964A1 (en) * 2005-12-30 2009-09-17 Gilead Sciences, Inc. Methods for improving the pharmacokinetics of hiv integrase inhibitors
AU2013203476C1 (en) * 2005-12-30 2016-11-17 Gilead Sciences, Inc. Methods for improving the pharmacokinetics of hiv integrase inhibitors
JP2009525261A (ja) * 2006-02-01 2009-07-09 日本たばこ産業株式会社 レトロウイルス感染症の治療のための、６−（３−クロロ−２−フルオロベンジル）−１−［（２ｓ）−１−ヒドロキシ−３−メチルブタン−２−イル］−７−メトキシ−４−オキソ−１，４−ジヒドロキノリン−３−カルボン酸またはその塩の使用
WO2007092802A1 (en) * 2006-02-09 2007-08-16 Boehringer Ingelheim International Gmbh Method for treating hiv infection through co-administration of tipranavir and gs 9137
EA017861B9 (ru) 2006-03-06 2014-05-30 Джапан Тобакко Инк. Способ получения 4-оксохинолинового соединения
US8420821B2 (en) 2006-03-06 2013-04-16 Japan Tobacco Inc. Process for production of 4-oxoquinoline compound
ES2796275T3 (es) 2006-07-07 2020-11-26 Gilead Sciences Inc Moduladores de propiedades farmacocinéticas de agentes terapéuticos
SG10201501782UA (en) 2006-09-12 2015-05-28 Gilead Sciences Inc Process and intermediates for preparing integrase inhibitors
ES2601820T5 (es) 2007-02-23 2024-10-31 Gilead Sciences Inc Moduladores de propiedades terapéutica de las farmacocinéticas
EA200971093A1 (ru) * 2007-06-29 2010-08-30 Джилид Сайэнс, Инк. Терапевтические композиции и их применение
JP5547067B2 (ja) * 2007-06-29 2014-07-09 ギリアード サイエンシーズ， インコーポレイテッド 治療組成物およびその使用
AR068403A1 (es) 2007-09-11 2009-11-18 Gilead Sciences Inc Proceso e intermediarios para la preparacion de inhibidores de integrasa
SG10201609006WA (en) 2008-05-02 2016-12-29 Gilead Sciences Inc The use of solid carrier particles to improve the processability of a pharmaceutical agent
PT2393485E (pt) 2009-02-06 2015-10-23 Gilead Sciences Inc Comprimidos bicamada que compreendem elvitegravir, cobicistat, emtricitabina e tenofovir
WO2010137032A2 (en) * 2009-05-14 2010-12-02 Matrix Laboratories Ltd. Novel polymorphic forms of elvitegravir and its pharmaceutically acceptable salts
WO2011004389A2 (en) * 2009-06-18 2011-01-13 Matrix Laboratories Ltd An improved process for the preparation of elvitegravir
CN102212032B (zh) * 2011-04-20 2013-07-31 复旦大学 一种5-羟基喹诺酮类衍生物及其制备方法和用途
CA2878478A1 (en) 2012-07-06 2014-01-09 Genentech, Inc. N-substituted benzamides and methods of use thereof
IN2015DN01688A (pm) 2012-08-03 2015-07-03 Gilead Sciences Inc
CN103819402B (zh) * 2012-11-17 2016-03-30 上海迪赛诺化学制药有限公司 埃替拉韦中间体及其制备方法和应用
CN103864682B (zh) * 2012-12-18 2016-12-28 上海迪赛诺化学制药有限公司 一种制备iii型埃替拉韦晶体的方法
HUE028284T2 (en) 2012-12-21 2016-12-28 Gilead Sciences Inc Polycyclic carbamoylpyridone compounds and their pharmaceutical use
SI3252058T1 (sl) 2013-07-12 2021-03-31 Gilead Sciences, Inc. Policiklične karbamoilpiridonske spojine in njihova uporaba za zdravljenje okužb s HIV
NO2865735T3 (pm) 2013-07-12 2018-07-21
CN105315203A (zh) * 2014-06-06 2016-02-10 上海迪赛诺化学制药有限公司 一种v型埃替拉韦晶体及其制备方法
TWI744723B (zh) 2014-06-20 2021-11-01 美商基利科學股份有限公司 多環型胺甲醯基吡啶酮化合物之合成
TW201613936A (en) 2014-06-20 2016-04-16 Gilead Sciences Inc Crystalline forms of(2R,5S,13aR)-8-hydroxy-7,9-dioxo-n-(2,4,6-trifluorobenzyl)-2,3,4,5,7,9,13,13a-octahydro-2,5-methanopyrido[1',2':4,5]pyrazino[2,1-b][1,3]oxazepine-10-carboxamide
NO2717902T3 (pm) 2014-06-20 2018-06-23
TWI738321B (zh) 2014-12-23 2021-09-01 美商基利科學股份有限公司 多環胺甲醯基吡啶酮化合物及其醫藥用途
EP3277691B1 (en) 2015-04-02 2019-01-30 Gilead Sciences, Inc. Polycyclic-carbamoylpyridone compounds and their pharmaceutical use
CN106008195B (zh) * 2016-05-19 2018-08-03 绍兴文理学院 一种2，4-二氟-5-碘苯甲酸的制备方法
EP3984536B1 (en) * 2020-10-19 2025-06-25 Centre national de la recherche scientifique Inhibition of the hiv-1 replication by compounds directed against a new target of the viral cycle

Family Cites Families (37)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3472859A (en) * 1966-11-01 1969-10-14 Sterling Drug Inc 1-alkyl-1,4-dihydro-4-oxo-3 quinoline-carboxylic acids and esters
JPS567162B1 (pm) 1970-09-14 1981-02-16
JPS4826772A (pm) 1971-08-11 1973-04-09
JPS6450979A (en) 1987-08-21 1989-02-27 Hitachi Shipbuilding Eng Co Method for discriminating whistle sound
JPH0651229B2 (ja) 1989-07-31 1994-07-06 新日本製鐵株式会社 プラズマアーク溶接方法および装置
IL100555A (en) 1991-02-07 2000-08-31 Hoechst Marion Roussel Inc N-substituted quinoline derivatives their preparation their use for the preparation of medicaments and the pharmaceutical compositions containing them
NO304832B1 (no) 1992-05-27 1999-02-22 Ube Industries Aminokinolonderivater samt middel mot HIV
JP2993316B2 (ja) 1992-05-27 1999-12-20 宇部興産株式会社 アリール基又は複素芳香環基置換アミノキノロン誘導体及びエイズ治療剤
JPH06199835A (ja) 1993-01-08 1994-07-19 Hokuriku Seiyaku Co Ltd ８−ジフルオロメトキシキノリン−３−カルボン酸誘導体
JPH06271568A (ja) 1993-03-22 1994-09-27 Hokuriku Seiyaku Co Ltd ７−フェニルピペラジニルキノリン−３−カルボン酸誘導体
JP2930539B2 (ja) 1994-07-18 1999-08-03 三共株式会社 トリフルオロメチルキノリンカルボン酸誘導体
EP0773214A4 (en) 1994-07-18 1998-04-15 Ube Industries TRIFLUOROMETHYLQUINOLEINECARBOXYLIC ACID
JPH0826772A (ja) 1994-07-22 1996-01-30 Sony Corp 融着用ガラス、その製造方法及び製造装置、並びに磁気ヘッドの製造方法
AU725629B2 (en) 1996-04-12 2000-10-19 Government Of The United States Of America, As Represented By The Secretary Of The Department Of Health And Human Services, The Acridone-derived compounds useful as antineoplastic and antiretroviral agents
FR2761687B1 (fr) 1997-04-08 2000-09-15 Centre Nat Rech Scient Derives de quinoleines, possedant notamment des proprietes antivirales, leurs preparations et leurs applications biologiques
JP3776203B2 (ja) 1997-05-13 2006-05-17 第一製薬株式会社 Ｉｃａｍ−１産生阻害剤
GB9721964D0 (en) 1997-10-16 1997-12-17 Pfizer Ltd Isoquinolines
US6399629B1 (en) 1998-06-01 2002-06-04 Microcide Pharmaceuticals, Inc. Efflux pump inhibitors
SE9802549D0 (sv) * 1998-07-15 1998-07-15 Active Biotech Ab Quinoline derivatives
US6248739B1 (en) 1999-01-08 2001-06-19 Pharmacia & Upjohn Company Quinolinecarboxamides as antiviral agents
US6248736B1 (en) 1999-01-08 2001-06-19 Pharmacia & Upjohn Company 4-oxo-1,4-dihydro-3-quinolinecarboxamides as antiviral agents
PE20011349A1 (es) 2000-06-16 2002-01-19 Upjohn Co 1-aril-4-oxo-1,4-dihidro-3-quinolincarboxamidas como agentes antivirales
US6559145B2 (en) 2000-07-12 2003-05-06 Pharmacia & Upjohn Company Heterocycle carboxamides as antiviral agents
US20050010048A1 (en) 2000-10-12 2005-01-13 Linghang Zhuang Aza-and polyaza-naphthalenly ketones useful as hiv integrase inhibitors
AU2002246499B2 (en) 2000-10-12 2005-12-22 Merck & Co., Inc. Aza-and polyaza-naphthalenyl carboxamides useful as HIV integrase inhibitors
BR0207809A (pt) 2001-03-01 2004-03-09 Shionogi & Co Compostos heteroarila contendo nitrogênio possuindo atividade inibidora contra integrase de hiv
JP2002293745A (ja) 2001-03-29 2002-10-09 St Marianna Univ School Of Medicine 慢性関節リウマチ治療剤
US20030138483A1 (en) * 2001-05-25 2003-07-24 Sergio Petriconi Soft elastic capsules and compositions thereof
US6627646B2 (en) * 2001-07-17 2003-09-30 Sepracor Inc. Norastemizole polymorphs
FR2827600A1 (fr) 2001-07-20 2003-01-24 Lipha Derives acides de quinolone et leurs applications en therapeutique
RU2206564C1 (ru) * 2002-03-07 2003-06-20 Общество с ограниченной ответственностью "Поливит" Способ получения этилового эфира 6-фтор-7-хлор-1,4-дигидро-4-оксо-3-хинолинкарбоновой кислоты
JP4035765B2 (ja) 2002-10-31 2008-01-23 横河電機株式会社 フーリエ変換型赤外線分光計
JP3567162B1 (ja) 2002-11-20 2004-09-22 日本たばこ産業株式会社 ４−オキソキノリン化合物及びそのｈｉｖインテグラーゼ阻害剤としての利用
DK1564210T5 (da) * 2002-11-20 2010-05-03 Japan Tobacco Inc 4-Oxoquinolinforbindelser og anvendelse deraf som HIV-integraseinhibitorer
WO2005113509A1 (en) * 2004-05-20 2005-12-01 Japan Tobacco Inc. Novel 4-oxoquinoline compound and use thereof as hiv integrase inhibitor
MY134672A (en) * 2004-05-20 2007-12-31 Japan Tobacco Inc Stable crystal of 4-oxoquinoline compound
EP3287130A1 (en) 2004-05-21 2018-02-28 Japan Tobacco Inc. Combinations comprising a 4-isoquinolone derivative and protease inhibitors

Also Published As

Publication number Publication date
US20250091995A1 (en) 2025-03-20
PE20120361A1 (es) 2012-05-03
US7635704B2 (en) 2009-12-22
PT1636190E (pt) 2012-08-20
ES2960824T3 (es) 2024-03-06
SI3281939T1 (sl) 2024-02-29
NO20240384A1 (no) 2007-02-07
EP3281939A1 (en) 2018-02-14
EP1636190B1 (en) 2012-06-27
PL3281939T3 (pl) 2024-03-18
PE20060358A1 (es) 2006-05-12
WO2005113508A1 (en) 2005-12-01
US20060030710A1 (en) 2006-02-09
KR20080064909A (ko) 2008-07-09
CN1956961B (zh) 2010-05-26
TWI329015B (en) 2010-08-21
BE2024C511I2 (pm) 2024-10-08
CN1956961A (zh) 2007-05-02
SI1636190T1 (sl) 2012-09-28
NO20161297A1 (no) 2007-02-07
CA2566922A1 (en) 2005-12-01
PL1636190T3 (pl) 2012-10-31
NO20220690A1 (no) 2007-02-07
FIC20240008I1 (fi) 2024-03-20
MY134672A (en) 2007-12-31
CY1113010T1 (el) 2016-04-13
RS64845B1 (sr) 2023-12-29
US20180029989A1 (en) 2018-02-01
LUC00334I2 (pm) 2024-07-01
NO20065790L (no) 2007-02-07
HRP20120681T1 (hr) 2012-09-30
US20150361044A1 (en) 2015-12-17
LT3281939T (lt) 2023-11-27
NO2024034I1 (no) 2024-07-15
HK1083341A1 (en) 2006-06-30
BRPI0510114A (pt) 2007-09-25
EP3281939B1 (en) 2023-10-18
BRPI0510114B8 (pt) 2021-05-25
BRPI0510114B1 (pt) 2020-09-15
NO20190051A1 (no) 2007-02-07
CY2024008I1 (el) 2024-09-20
AR096100A2 (es) 2015-12-09
EP2514746A1 (en) 2012-10-24
EP4299563A3 (en) 2024-02-28
TW200600097A (en) 2006-01-01
US20190185433A1 (en) 2019-06-20
LTC3281939I2 (pm) 2025-04-25
HUS2400006I1 (hu) 2024-04-28
US20220235009A1 (en) 2022-07-28
ES2388441T3 (es) 2012-10-15
AU2005245296A1 (en) 2005-12-01
CY2024008I2 (el) 2024-09-20
DK3281939T3 (da) 2024-01-22
AU2005245296B2 (en) 2010-08-12
RS52375B (en) 2012-12-31
NO20230913A1 (no) 2007-02-07
HUE064615T2 (hu) 2024-04-28
US20100204271A1 (en) 2010-08-12
EP4299563A2 (en) 2024-01-03
RU2330845C1 (ru) 2008-08-10
JP2006001927A (ja) 2006-01-05
NO347902B1 (no) 2024-05-06
CY2015009I1 (el) 2024-09-20
ZA200610647B (en) 2008-06-25
DK1636190T3 (da) 2012-09-24
NO20200873A1 (no) 2007-02-07
NO339223B1 (no) 2016-11-21
CY1126560T1 (el) 2024-09-20
JP3754064B2 (ja) 2006-03-08
HRP20231588T3 (hr) 2024-03-15
MXPA06013405A (es) 2007-03-01
EP1636190A1 (en) 2006-03-22
AR049280A1 (es) 2006-07-12
PT3281939T (pt) 2023-11-22
FI3281939T3 (fi) 2023-10-23
CA2566922C (en) 2011-01-11
IL179250A0 (en) 2007-03-08
US8981103B2 (en) 2015-03-17
NZ551839A (en) 2009-11-27
LTPA2024001I1 (pm) 2024-04-10
CY2015009I2 (el) 2024-09-20

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