RS64845B1 - Kombinacija koja se sastoji od stabilnog kristala 4-oksohinolinskog jedinjenja - Google Patents

Kombinacija koja se sastoji od stabilnog kristala 4-oksohinolinskog jedinjenja

Info

Publication number
RS64845B1
RS64845B1 RS20231092A RSP20231092A RS64845B1 RS 64845 B1 RS64845 B1 RS 64845B1 RS 20231092 A RS20231092 A RS 20231092A RS P20231092 A RSP20231092 A RS P20231092A RS 64845 B1 RS64845 B1 RS 64845B1
Authority
RS
Serbia
Prior art keywords
combination
stable crystal
oxoquinoline compound
oxoquinoline
compound
Prior art date
Application number
RS20231092A
Other languages
English (en)
Inventor
Motohide Satoh
Takahisa Motomura
Takashi Matsuda
Kentaro Kondo
Koji Ando
Koji Matsuda
Shuji Miyake
Hideto Uehara
Original Assignee
Japan Tobacco Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=35079161&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=RS64845(B1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Japan Tobacco Inc filed Critical Japan Tobacco Inc
Publication of RS64845B1 publication Critical patent/RS64845B1/sr

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/48—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • C07D215/54—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 3
    • C07D215/56—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 3 with oxygen atoms in position 4
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Virology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Molecular Biology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • AIDS & HIV (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Quinoline Compounds (AREA)
RS20231092A 2004-05-20 2005-05-19 Kombinacija koja se sastoji od stabilnog kristala 4-oksohinolinskog jedinjenja RS64845B1 (sr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2004150979 2004-05-20
EP17186674.2A EP3281939B1 (en) 2004-05-20 2005-05-19 Combination comprising a stable crystal of a 4-oxoquinoline compound

Publications (1)

Publication Number Publication Date
RS64845B1 true RS64845B1 (sr) 2023-12-29

Family

ID=35079161

Family Applications (2)

Application Number Title Priority Date Filing Date
RS20231092A RS64845B1 (sr) 2004-05-20 2005-05-19 Kombinacija koja se sastoji od stabilnog kristala 4-oksohinolinskog jedinjenja
RS20120306A RS52375B (sr) 2004-05-20 2005-05-19 Stabilni kristali jedinjenja 4-oksohinolina

Family Applications After (1)

Application Number Title Priority Date Filing Date
RS20120306A RS52375B (sr) 2004-05-20 2005-05-19 Stabilni kristali jedinjenja 4-oksohinolina

Country Status (33)

Country Link
US (6) US7635704B2 (sr)
EP (4) EP3281939B1 (sr)
JP (1) JP3754064B2 (sr)
KR (1) KR20080064909A (sr)
CN (1) CN1956961B (sr)
AR (2) AR049280A1 (sr)
AU (1) AU2005245296B2 (sr)
BR (1) BRPI0510114B8 (sr)
CA (1) CA2566922C (sr)
CY (1) CY1113010T1 (sr)
DK (2) DK3281939T3 (sr)
ES (2) ES2388441T3 (sr)
FI (2) FI3281939T3 (sr)
FR (1) FR23C1040I1 (sr)
HK (1) HK1083341A1 (sr)
HR (2) HRP20231588T3 (sr)
HU (2) HUE064615T2 (sr)
IL (1) IL179250A0 (sr)
LT (1) LT3281939T (sr)
LU (1) LUC00334I2 (sr)
MX (1) MXPA06013405A (sr)
MY (1) MY134672A (sr)
NO (6) NO339223B1 (sr)
NZ (1) NZ551839A (sr)
PE (2) PE20120361A1 (sr)
PL (2) PL1636190T3 (sr)
PT (2) PT3281939T (sr)
RS (2) RS64845B1 (sr)
RU (1) RU2330845C1 (sr)
SI (2) SI3281939T1 (sr)
TW (1) TWI329015B (sr)
WO (1) WO2005113508A1 (sr)
ZA (1) ZA200610647B (sr)

Families Citing this family (37)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6891227B2 (en) 2002-03-20 2005-05-10 International Business Machines Corporation Self-aligned nanotube field effect transistor and method of fabricating same
CZ2004764A3 (cs) * 2002-11-20 2005-02-16 Japan Tobacco Inc 4-Oxochinolinová sloučenina a její použití jako inhibitoru HIV-integrázy
MY134672A (en) * 2004-05-20 2007-12-31 Japan Tobacco Inc Stable crystal of 4-oxoquinoline compound
WO2007063869A1 (ja) * 2005-11-30 2007-06-07 Japan Tobacco Inc. 高純度キノロン化合物の製造方法
AU2013203476C1 (en) * 2005-12-30 2016-11-17 Gilead Sciences, Inc. Methods for improving the pharmacokinetics of hiv integrase inhibitors
US20090233964A1 (en) * 2005-12-30 2009-09-17 Gilead Sciences, Inc. Methods for improving the pharmacokinetics of hiv integrase inhibitors
CA2635468C (en) 2005-12-30 2016-08-09 Gilead Sciences, Inc. Methods for improving the pharmacokinetics of hiv integrase inhibitors
JP2009525261A (ja) * 2006-02-01 2009-07-09 日本たばこ産業株式会社 レトロウイルス感染症の治療のための、６−（３−クロロ−２−フルオロベンジル）−１−［（２ｓ）−１−ヒドロキシ−３−メチルブタン−２−イル］−７−メトキシ−４−オキソ−１，４−ジヒドロキノリン−３−カルボン酸またはその塩の使用
WO2007092802A1 (en) * 2006-02-09 2007-08-16 Boehringer Ingelheim International Gmbh Method for treating hiv infection through co-administration of tipranavir and gs 9137
US8420821B2 (en) 2006-03-06 2013-04-16 Japan Tobacco Inc. Process for production of 4-oxoquinoline compound
US8383819B2 (en) * 2006-03-06 2013-02-26 Japan Tobacco Inc. Method for producing 4-oxoquinoline compound
KR20140004808A (ko) 2006-07-07 2014-01-13 길리애드 사이언시즈, 인코포레이티드 치료제의 약동학 특성의 모듈레이터
CN101516819B (zh) 2006-09-12 2013-10-16 吉里德科学公司 制备整合酶抑制剂的方法和中间体
PL2487161T3 (pl) 2007-02-23 2017-03-31 Gilead Sciences, Inc. Modulatory farmakokinetycznych właściwości środków terapeutycznych
TW200914011A (en) * 2007-06-29 2009-04-01 Gilead Sciences Inc Therapeutic compositions and methods
KR20100028656A (ko) * 2007-06-29 2010-03-12 길리애드 사이언시즈, 인코포레이티드 치료 조성물 및 그의 용도
AR068403A1 (es) 2007-09-11 2009-11-18 Gilead Sciences Inc Proceso e intermediarios para la preparacion de inhibidores de integrasa
SG190618A1 (en) 2008-05-02 2013-06-28 Gilead Sciences Inc The use of solid carrier particles to improve the processability of a pharmaceutical agent
HUE025822T2 (en) 2009-02-06 2016-04-28 Gilead Sciences Inc Dual layer tablets containing Elvitegravir, Cobicistat, Emtricitabine and Tenofovir
WO2010137032A2 (en) * 2009-05-14 2010-12-02 Matrix Laboratories Ltd. Novel polymorphic forms of elvitegravir and its pharmaceutically acceptable salts
WO2011004389A2 (en) * 2009-06-18 2011-01-13 Matrix Laboratories Ltd An improved process for the preparation of elvitegravir
CN102212032B (zh) * 2011-04-20 2013-07-31 复旦大学 一种5-羟基喹诺酮类衍生物及其制备方法和用途
JP6309519B2 (ja) 2012-07-06 2018-04-11 ジェネンテック， インコーポレイテッド Ｎ置換ベンズアミド及びその使用方法
AU2013296289B2 (en) 2012-08-03 2017-10-05 Gilead Sciences, Inc. Process and intermediates for preparing integrase inhibitors
CN103819402B (zh) * 2012-11-17 2016-03-30 上海迪赛诺化学制药有限公司 埃替拉韦中间体及其制备方法和应用
CN103864682B (zh) * 2012-12-18 2016-12-28 上海迪赛诺化学制药有限公司 一种制备iii型埃替拉韦晶体的方法
PT3608325T (pt) 2012-12-21 2022-10-17 Gilead Sciences Inc Compostos carbamoílpiridona policíclicos e sua utilização farmacêutica
PT3019503T (pt) 2013-07-12 2017-11-27 Gilead Sciences Inc Compostos carbamoílpiridona- policíclicos e seu uso para o tratamento de infecções por hiv
NO2865735T3 (sr) 2013-07-12 2018-07-21
CN105315203A (zh) * 2014-06-06 2016-02-10 上海迪赛诺化学制药有限公司 一种v型埃替拉韦晶体及其制备方法
NO2717902T3 (sr) 2014-06-20 2018-06-23
TWI677489B (zh) 2014-06-20 2019-11-21 美商基利科學股份有限公司 多環型胺甲醯基吡啶酮化合物之合成
TW201613936A (en) 2014-06-20 2016-04-16 Gilead Sciences Inc Crystalline forms of(2R,5S,13aR)-8-hydroxy-7,9-dioxo-n-(2,4,6-trifluorobenzyl)-2,3,4,5,7,9,13,13a-octahydro-2,5-methanopyrido[1',2':4,5]pyrazino[2,1-b][1,3]oxazepine-10-carboxamide
TWI695003B (zh) 2014-12-23 2020-06-01 美商基利科學股份有限公司 多環胺甲醯基吡啶酮化合物及其醫藥用途
PL3277691T3 (pl) 2015-04-02 2019-07-31 Gilead Sciences, Inc. Policykliczne związki karbamoilopirydonowe i ich zastosowanie farmaceutyczne
CN106008195B (zh) * 2016-05-19 2018-08-03 绍兴文理学院 一种2，4-二氟-5-碘苯甲酸的制备方法
EP3984536A1 (en) * 2020-10-19 2022-04-20 Centre national de la recherche scientifique Inhibition of the hiv-1 replication by compounds directed against a new target of the viral cycle

Family Cites Families (35)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3472859A (en) * 1966-11-01 1969-10-14 Sterling Drug Inc 1-alkyl-1,4-dihydro-4-oxo-3 quinoline-carboxylic acids and esters
JPS567162B1 (sr) 1970-09-14 1981-02-16
JPS4826772A (sr) 1971-08-11 1973-04-09
JPS6450979A (en) 1987-08-21 1989-02-27 Hitachi Shipbuilding Eng Co Method for discriminating whistle sound
JPH0651229B2 (ja) 1989-07-31 1994-07-06 新日本製鐵株式会社 プラズマアーク溶接方法および装置
IL100555A (en) 1991-02-07 2000-08-31 Hoechst Marion Roussel Inc N-substituted quinoline derivatives their preparation their use for the preparation of medicaments and the pharmaceutical compositions containing them
NO304832B1 (no) 1992-05-27 1999-02-22 Ube Industries Aminokinolonderivater samt middel mot HIV
JP2993316B2 (ja) 1992-05-27 1999-12-20 宇部興産株式会社 アリール基又は複素芳香環基置換アミノキノロン誘導体及びエイズ治療剤
JPH06199835A (ja) 1993-01-08 1994-07-19 Hokuriku Seiyaku Co Ltd ８−ジフルオロメトキシキノリン−３−カルボン酸誘導体
JPH06271568A (ja) 1993-03-22 1994-09-27 Hokuriku Seiyaku Co Ltd ７−フェニルピペラジニルキノリン−３−カルボン酸誘導体
EP0773214A4 (en) 1994-07-18 1998-04-15 Ube Industries TRIFLUORMETHYLQUINOLINE CARBONIC ACID DERIVATIVES
JP2930539B2 (ja) 1994-07-18 1999-08-03 三共株式会社 トリフルオロメチルキノリンカルボン酸誘導体
JPH0826772A (ja) 1994-07-22 1996-01-30 Sony Corp 融着用ガラス、その製造方法及び製造装置、並びに磁気ヘッドの製造方法
AU725629B2 (en) 1996-04-12 2000-10-19 Government Of The United States Of America, As Represented By The Secretary Of The Department Of Health And Human Services, The Acridone-derived compounds useful as antineoplastic and antiretroviral agents
FR2761687B1 (fr) * 1997-04-08 2000-09-15 Centre Nat Rech Scient Derives de quinoleines, possedant notamment des proprietes antivirales, leurs preparations et leurs applications biologiques
JP3776203B2 (ja) 1997-05-13 2006-05-17 第一製薬株式会社 Ｉｃａｍ−１産生阻害剤
GB9721964D0 (en) 1997-10-16 1997-12-17 Pfizer Ltd Isoquinolines
US6399629B1 (en) 1998-06-01 2002-06-04 Microcide Pharmaceuticals, Inc. Efflux pump inhibitors
US6248739B1 (en) 1999-01-08 2001-06-19 Pharmacia & Upjohn Company Quinolinecarboxamides as antiviral agents
US6248736B1 (en) 1999-01-08 2001-06-19 Pharmacia & Upjohn Company 4-oxo-1,4-dihydro-3-quinolinecarboxamides as antiviral agents
PE20011349A1 (es) 2000-06-16 2002-01-19 Upjohn Co 1-aril-4-oxo-1,4-dihidro-3-quinolincarboxamidas como agentes antivirales
US6559145B2 (en) 2000-07-12 2003-05-06 Pharmacia & Upjohn Company Heterocycle carboxamides as antiviral agents
WO2002036734A2 (en) 2000-10-12 2002-05-10 Merck & Co., Inc. Aza-and polyaza-naphthalenyl ketones useful as hiv integrase inhibitors
US6841558B2 (en) 2000-10-12 2005-01-11 Merck & Co., Inc. Aza-and polyaza-naphthalenyl carboxamides useful as HIV intergrase inhibitors
KR20030078958A (ko) 2001-03-01 2003-10-08 시오노기세이야쿠가부시키가이샤 Ｈｉｖ 인테그라제 저해 활성을 갖는 질소 함유의헤테로아릴 화합물
JP2002293745A (ja) 2001-03-29 2002-10-09 St Marianna Univ School Of Medicine 慢性関節リウマチ治療剤
US20030138483A1 (en) * 2001-05-25 2003-07-24 Sergio Petriconi Soft elastic capsules and compositions thereof
US6627646B2 (en) * 2001-07-17 2003-09-30 Sepracor Inc. Norastemizole polymorphs
FR2827600A1 (fr) 2001-07-20 2003-01-24 Lipha Derives acides de quinolone et leurs applications en therapeutique
JP4035765B2 (ja) 2002-10-31 2008-01-23 横河電機株式会社 フーリエ変換型赤外線分光計
CZ2004764A3 (cs) * 2002-11-20 2005-02-16 Japan Tobacco Inc 4-Oxochinolinová sloučenina a její použití jako inhibitoru HIV-integrázy
JP3567162B1 (ja) 2002-11-20 2004-09-22 日本たばこ産業株式会社 ４−オキソキノリン化合物及びそのｈｉｖインテグラーゼ阻害剤としての利用
US7531554B2 (en) * 2004-05-20 2009-05-12 Japan Tobacco Inc. 4-oxoquinoline compound and use thereof as HIV integrase inhibitor
MY134672A (en) * 2004-05-20 2007-12-31 Japan Tobacco Inc Stable crystal of 4-oxoquinoline compound
EP3287130A1 (en) 2004-05-21 2018-02-28 Japan Tobacco Inc. Combinations comprising a 4-isoquinolone derivative and protease inhibitors

Also Published As

Publication number Publication date
NO20230913A1 (no) 2007-02-07
AU2005245296B2 (en) 2010-08-12
CY1113010T1 (el) 2016-04-13
JP3754064B2 (ja) 2006-03-08
US20150361044A1 (en) 2015-12-17
IL179250A0 (en) 2007-03-08
EP4299563A2 (en) 2024-01-03
NO20190051A1 (no) 2007-02-07
TW200600097A (en) 2006-01-01
SI3281939T1 (sl) 2024-02-29
HRP20231588T3 (hr) 2024-03-15
KR20080064909A (ko) 2008-07-09
HRP20120681T1 (hr) 2012-09-30
CN1956961B (zh) 2010-05-26
EP4299563A3 (en) 2024-02-28
CA2566922A1 (en) 2005-12-01
US20060030710A1 (en) 2006-02-09
ES2960824T3 (es) 2024-03-06
NO20161297A1 (no) 2007-02-07
LUC00334I2 (sr) 2024-07-01
PT3281939T (pt) 2023-11-22
JP2006001927A (ja) 2006-01-05
EP3281939A1 (en) 2018-02-14
US20100204271A1 (en) 2010-08-12
AR096100A2 (es) 2015-12-09
FIC20240008I1 (fi) 2024-03-20
ES2388441T3 (es) 2012-10-15
EP3281939B1 (en) 2023-10-18
HK1083341A1 (en) 2006-06-30
NO20220690A1 (no) 2007-02-07
US20180029989A1 (en) 2018-02-01
HUS2400006I1 (hu) 2024-04-28
AU2005245296A1 (en) 2005-12-01
PE20120361A1 (es) 2012-05-03
PT1636190E (pt) 2012-08-20
NZ551839A (en) 2009-11-27
FI3281939T3 (fi) 2023-10-23
US7635704B2 (en) 2009-12-22
HUE064615T2 (hu) 2024-04-28
BRPI0510114B1 (pt) 2020-09-15
CN1956961A (zh) 2007-05-02
US20190185433A1 (en) 2019-06-20
EP1636190B1 (en) 2012-06-27
MY134672A (en) 2007-12-31
DK3281939T3 (da) 2024-01-22
ZA200610647B (en) 2008-06-25
LT3281939T (lt) 2023-11-27
EP2514746A1 (en) 2012-10-24
PL1636190T3 (pl) 2012-10-31
NO347902B1 (no) 2024-05-06
EP1636190A1 (en) 2006-03-22
BRPI0510114A (pt) 2007-09-25
FR23C1040I1 (fr) 2023-12-29
WO2005113508A1 (en) 2005-12-01
NO339223B1 (no) 2016-11-21
RU2330845C1 (ru) 2008-08-10
PL3281939T3 (pl) 2024-03-18
MXPA06013405A (es) 2007-03-01
SI1636190T1 (sl) 2012-09-28
NO20200873A1 (no) 2007-02-07
AR049280A1 (es) 2006-07-12
NO20065790L (no) 2007-02-07
US8981103B2 (en) 2015-03-17
US20220235009A1 (en) 2022-07-28
TWI329015B (en) 2010-08-21
BRPI0510114B8 (pt) 2021-05-25
PE20060358A1 (es) 2006-05-12
DK1636190T3 (da) 2012-09-24
CA2566922C (en) 2011-01-11
RS52375B (sr) 2012-12-31

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