FIC20240008I1 - Elvitegraviiri ja tenofoviirialafenamidi - Google Patents

Elvitegraviiri ja tenofoviirialafenamidi

Info

Publication number
FIC20240008I1
FIC20240008I1 FIC20240008C FIC20240008C FIC20240008I1 FI C20240008 I1 FIC20240008 I1 FI C20240008I1 FI C20240008 C FIC20240008 C FI C20240008C FI C20240008 C FIC20240008 C FI C20240008C FI C20240008 I1 FIC20240008 I1 FI C20240008I1
Authority
FI
Finland
Prior art keywords
elvitegravir
tenofovir alafenamide
alafenamide
tenofovir
Prior art date
Application number
FIC20240008C
Other languages
English (en)
Original Assignee
Japan Tobacco Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=35079161&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=FIC20240008(I1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Japan Tobacco Inc filed Critical Japan Tobacco Inc
Publication of FIC20240008I1 publication Critical patent/FIC20240008I1/fi

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/48—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • C07D215/54—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 3
    • C07D215/56—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 3 with oxygen atoms in position 4
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Virology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Communicable Diseases (AREA)
  • AIDS & HIV (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Molecular Biology (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Quinoline Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
FIC20240008C 2004-05-20 2024-03-20 Elvitegraviiri ja tenofoviirialafenamidi FIC20240008I1 (fi)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP2004150979 2004-05-20

Publications (1)

Publication Number Publication Date
FIC20240008I1 true FIC20240008I1 (fi) 2024-03-20

Family

ID=35079161

Family Applications (2)

Application Number Title Priority Date Filing Date
FIEP17186674.2T FI3281939T3 (fi) 2004-05-20 2005-05-19 Yhdistelmä, joka sisältää 4-oksokinoliiniyhdisteen stabiilin kiteen
FIC20240008C FIC20240008I1 (fi) 2004-05-20 2024-03-20 Elvitegraviiri ja tenofoviirialafenamidi

Family Applications Before (1)

Application Number Title Priority Date Filing Date
FIEP17186674.2T FI3281939T3 (fi) 2004-05-20 2005-05-19 Yhdistelmä, joka sisältää 4-oksokinoliiniyhdisteen stabiilin kiteen

Country Status (33)

Country Link
US (6) US7635704B2 (fi)
EP (4) EP3281939B1 (fi)
JP (1) JP3754064B2 (fi)
KR (1) KR20080064909A (fi)
CN (1) CN1956961B (fi)
AR (2) AR049280A1 (fi)
AU (1) AU2005245296B2 (fi)
BR (1) BRPI0510114B8 (fi)
CA (1) CA2566922C (fi)
CY (1) CY1113010T1 (fi)
DK (2) DK1636190T3 (fi)
ES (2) ES2960824T3 (fi)
FI (2) FI3281939T3 (fi)
FR (1) FR23C1040I1 (fi)
HK (1) HK1083341A1 (fi)
HR (2) HRP20231588T3 (fi)
HU (2) HUE064615T2 (fi)
IL (1) IL179250A0 (fi)
LT (1) LT3281939T (fi)
LU (1) LUC00334I2 (fi)
MX (1) MXPA06013405A (fi)
MY (1) MY134672A (fi)
NO (6) NO339223B1 (fi)
NZ (1) NZ551839A (fi)
PE (2) PE20120361A1 (fi)
PL (2) PL3281939T3 (fi)
PT (2) PT1636190E (fi)
RS (2) RS52375B (fi)
RU (1) RU2330845C1 (fi)
SI (2) SI1636190T1 (fi)
TW (1) TWI329015B (fi)
WO (1) WO2005113508A1 (fi)
ZA (1) ZA200610647B (fi)

Families Citing this family (37)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6891227B2 (en) 2002-03-20 2005-05-10 International Business Machines Corporation Self-aligned nanotube field effect transistor and method of fabricating same
EP2272516A3 (en) * 2002-11-20 2011-03-16 Japan Tobacco, Inc. 4-Oxoquinoline compound and use thereof as HIV integrase inhibitor
MY134672A (en) * 2004-05-20 2007-12-31 Japan Tobacco Inc Stable crystal of 4-oxoquinoline compound
WO2007063869A1 (ja) * 2005-11-30 2007-06-07 Japan Tobacco Inc. 高純度キノロン化合物の製造方法
JP4676536B2 (ja) * 2005-12-30 2011-04-27 ギリアド サイエンシズ， インコーポレイテッド Ｈｉｖインテグラーゼ阻害剤の薬物動態の改善方法
US20090233964A1 (en) * 2005-12-30 2009-09-17 Gilead Sciences, Inc. Methods for improving the pharmacokinetics of hiv integrase inhibitors
AU2013203476C1 (en) * 2005-12-30 2016-11-17 Gilead Sciences, Inc. Methods for improving the pharmacokinetics of hiv integrase inhibitors
EP2452682A1 (en) 2006-02-01 2012-05-16 Japan Tobacco, Inc. Use of 6-(3-chloro-2-fluorobenzyl)-1-[(2s)-1-hydroxy-3-methylbutan-2-yl]-7-methoxy-4-oxo-1,4-dihydroquinoline-3-carboxylic acid or salt thereof for treating retrovirus infection
WO2007092802A1 (en) * 2006-02-09 2007-08-16 Boehringer Ingelheim International Gmbh Method for treating hiv infection through co-administration of tipranavir and gs 9137
AP2914A (en) * 2006-03-06 2014-05-31 Japan Tobacco Inc Method for producing 4-oxoquinoline compound
IN2014CN00532A (fi) 2006-03-06 2015-04-03 Japan Tobacco Inc
KR20140004808A (ko) 2006-07-07 2014-01-13 길리애드 사이언시즈, 인코포레이티드 치료제의 약동학 특성의 모듈레이터
SG10201501782UA (en) 2006-09-12 2015-05-28 Gilead Sciences Inc Process and intermediates for preparing integrase inhibitors
ES2603617T3 (es) 2007-02-23 2017-02-28 Gilead Sciences, Inc. Moduladores de propiedades farmacocinéticas de la terapéutica
KR20100028656A (ko) * 2007-06-29 2010-03-12 길리애드 사이언시즈, 인코포레이티드 치료 조성물 및 그의 용도
CN103480000A (zh) * 2007-06-29 2014-01-01 吉里德科学公司 治疗用组合物和方法
AR068403A1 (es) 2007-09-11 2009-11-18 Gilead Sciences Inc Proceso e intermediarios para la preparacion de inhibidores de integrasa
WO2009135179A2 (en) 2008-05-02 2009-11-05 Gilead Sciences, Inc. The use of solid carrier particles to improve the processability of a pharmaceutical agent
KR101738325B1 (ko) 2009-02-06 2017-05-19 길리애드 사이언시즈, 인코포레이티드 조합 요법용 정제
WO2010137032A2 (en) * 2009-05-14 2010-12-02 Matrix Laboratories Ltd. Novel polymorphic forms of elvitegravir and its pharmaceutically acceptable salts
WO2011004389A2 (en) * 2009-06-18 2011-01-13 Matrix Laboratories Ltd An improved process for the preparation of elvitegravir
CN102212032B (zh) * 2011-04-20 2013-07-31 复旦大学 一种5-羟基喹诺酮类衍生物及其制备方法和用途
CN104797555B (zh) 2012-07-06 2017-12-22 基因泰克公司 N‑取代的苯甲酰胺及其使用方法
KR20150040340A (ko) 2012-08-03 2015-04-14 길리애드 사이언시즈, 인코포레이티드 인테그라아제 저해제 제조를 위한 방법 및 중간체
CN103819402B (zh) * 2012-11-17 2016-03-30 上海迪赛诺化学制药有限公司 埃替拉韦中间体及其制备方法和应用
CN103864682B (zh) * 2012-12-18 2016-12-28 上海迪赛诺化学制药有限公司 一种制备iii型埃替拉韦晶体的方法
MD4754C1 (ro) 2012-12-21 2021-12-31 Gilead Sciences, Inc. Compuşi policiclici de carbamoilpiridonă şi utilizarea lor farmaceutică
AU2014286993B2 (en) 2013-07-12 2018-10-25 Gilead Sciences, Inc. Polycyclic-carbamoylpyridone compounds and their use for the treatment of HIV infections
NO2865735T3 (fi) 2013-07-12 2018-07-21
CN105315203A (zh) * 2014-06-06 2016-02-10 上海迪赛诺化学制药有限公司 一种v型埃替拉韦晶体及其制备方法
TW201613936A (en) 2014-06-20 2016-04-16 Gilead Sciences Inc Crystalline forms of(2R,5S,13aR)-8-hydroxy-7,9-dioxo-n-(2,4,6-trifluorobenzyl)-2,3,4,5,7,9,13,13a-octahydro-2,5-methanopyrido[1',2':4,5]pyrazino[2,1-b][1,3]oxazepine-10-carboxamide
NO2717902T3 (fi) 2014-06-20 2018-06-23
TWI677489B (zh) 2014-06-20 2019-11-21 美商基利科學股份有限公司 多環型胺甲醯基吡啶酮化合物之合成
TWI695003B (zh) 2014-12-23 2020-06-01 美商基利科學股份有限公司 多環胺甲醯基吡啶酮化合物及其醫藥用途
TR201905009T4 (tr) 2015-04-02 2019-05-21 Gilead Sciences Inc Polisiklik-karbamoilpiridon bileşikleri ve bunların farmasötik kullanımları.
CN106008195B (zh) * 2016-05-19 2018-08-03 绍兴文理学院 一种2，4-二氟-5-碘苯甲酸的制备方法
EP3984536A1 (en) * 2020-10-19 2022-04-20 Centre national de la recherche scientifique Inhibition of the hiv-1 replication by compounds directed against a new target of the viral cycle

Family Cites Families (35)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3472859A (en) * 1966-11-01 1969-10-14 Sterling Drug Inc 1-alkyl-1,4-dihydro-4-oxo-3 quinoline-carboxylic acids and esters
JPS567162B1 (fi) 1970-09-14 1981-02-16
JPS4826772A (fi) 1971-08-11 1973-04-09
JPS6450979A (en) 1987-08-21 1989-02-27 Hitachi Shipbuilding Eng Co Method for discriminating whistle sound
JPH0651229B2 (ja) 1989-07-31 1994-07-06 新日本製鐵株式会社 プラズマアーク溶接方法および装置
IL100555A (en) 1991-02-07 2000-08-31 Hoechst Marion Roussel Inc N-substituted quinoline derivatives their preparation their use for the preparation of medicaments and the pharmaceutical compositions containing them
NO304832B1 (no) 1992-05-27 1999-02-22 Ube Industries Aminokinolonderivater samt middel mot HIV
JP2993316B2 (ja) 1992-05-27 1999-12-20 宇部興産株式会社 アリール基又は複素芳香環基置換アミノキノロン誘導体及びエイズ治療剤
JPH06199835A (ja) 1993-01-08 1994-07-19 Hokuriku Seiyaku Co Ltd ８−ジフルオロメトキシキノリン−３−カルボン酸誘導体
JPH06271568A (ja) 1993-03-22 1994-09-27 Hokuriku Seiyaku Co Ltd ７−フェニルピペラジニルキノリン−３−カルボン酸誘導体
JP2930539B2 (ja) 1994-07-18 1999-08-03 三共株式会社 トリフルオロメチルキノリンカルボン酸誘導体
WO1996002512A1 (fr) 1994-07-18 1996-02-01 Ube Industries, Ltd. Acide du type trifluoromethylquinoleinecarboxylique
JPH0826772A (ja) 1994-07-22 1996-01-30 Sony Corp 融着用ガラス、その製造方法及び製造装置、並びに磁気ヘッドの製造方法
ES2171260T3 (es) 1996-04-12 2002-09-01 Us Gov Health & Human Serv Compuestos derivados de acridona utiles como agentes antineoplasicos y antirretroviricos.
FR2761687B1 (fr) * 1997-04-08 2000-09-15 Centre Nat Rech Scient Derives de quinoleines, possedant notamment des proprietes antivirales, leurs preparations et leurs applications biologiques
JP3776203B2 (ja) 1997-05-13 2006-05-17 第一製薬株式会社 Ｉｃａｍ−１産生阻害剤
GB9721964D0 (en) 1997-10-16 1997-12-17 Pfizer Ltd Isoquinolines
US6399629B1 (en) 1998-06-01 2002-06-04 Microcide Pharmaceuticals, Inc. Efflux pump inhibitors
US6248736B1 (en) 1999-01-08 2001-06-19 Pharmacia & Upjohn Company 4-oxo-1,4-dihydro-3-quinolinecarboxamides as antiviral agents
US6248739B1 (en) 1999-01-08 2001-06-19 Pharmacia & Upjohn Company Quinolinecarboxamides as antiviral agents
PE20011349A1 (es) 2000-06-16 2002-01-19 Upjohn Co 1-aril-4-oxo-1,4-dihidro-3-quinolincarboxamidas como agentes antivirales
US6559145B2 (en) 2000-07-12 2003-05-06 Pharmacia & Upjohn Company Heterocycle carboxamides as antiviral agents
ES2274913T3 (es) 2000-10-12 2007-06-01 MERCK & CO., INC. Aza y poliaza-naftalenil carboxamidas utiles como inhibidores de vih integrada.
US20050010048A1 (en) 2000-10-12 2005-01-13 Linghang Zhuang Aza-and polyaza-naphthalenly ketones useful as hiv integrase inhibitors
KR20030078958A (ko) 2001-03-01 2003-10-08 시오노기세이야쿠가부시키가이샤 Ｈｉｖ 인테그라제 저해 활성을 갖는 질소 함유의헤테로아릴 화합물
JP2002293745A (ja) 2001-03-29 2002-10-09 St Marianna Univ School Of Medicine 慢性関節リウマチ治療剤
US20030138483A1 (en) * 2001-05-25 2003-07-24 Sergio Petriconi Soft elastic capsules and compositions thereof
US6627646B2 (en) * 2001-07-17 2003-09-30 Sepracor Inc. Norastemizole polymorphs
FR2827600A1 (fr) 2001-07-20 2003-01-24 Lipha Derives acides de quinolone et leurs applications en therapeutique
JP4035765B2 (ja) 2002-10-31 2008-01-23 横河電機株式会社 フーリエ変換型赤外線分光計
JP3567162B1 (ja) 2002-11-20 2004-09-22 日本たばこ産業株式会社 ４−オキソキノリン化合物及びそのｈｉｖインテグラーゼ阻害剤としての利用
EP2272516A3 (en) * 2002-11-20 2011-03-16 Japan Tobacco, Inc. 4-Oxoquinoline compound and use thereof as HIV integrase inhibitor
MY134672A (en) * 2004-05-20 2007-12-31 Japan Tobacco Inc Stable crystal of 4-oxoquinoline compound
WO2005113509A1 (en) * 2004-05-20 2005-12-01 Japan Tobacco Inc. Novel 4-oxoquinoline compound and use thereof as hiv integrase inhibitor
WO2005112930A1 (en) 2004-05-21 2005-12-01 Japan Tobacco Inc. Combinations comprising a 4-isoquinolone derivative and anti-hiv agents

Also Published As

Publication number Publication date
LT3281939T (lt) 2023-11-27
FI3281939T3 (fi) 2023-10-23
RU2330845C1 (ru) 2008-08-10
FR23C1040I1 (fr) 2023-12-29
PL3281939T3 (pl) 2024-03-18
CA2566922C (en) 2011-01-11
NO20190051A1 (no) 2007-02-07
CA2566922A1 (en) 2005-12-01
US20100204271A1 (en) 2010-08-12
WO2005113508A1 (en) 2005-12-01
MY134672A (en) 2007-12-31
US8981103B2 (en) 2015-03-17
BRPI0510114B1 (pt) 2020-09-15
NO20220690A1 (no) 2007-02-07
SI3281939T1 (sl) 2024-02-29
CN1956961B (zh) 2010-05-26
IL179250A0 (en) 2007-03-08
AU2005245296B2 (en) 2010-08-12
RS52375B (en) 2012-12-31
NO20065790L (no) 2007-02-07
HUE064615T2 (hu) 2024-04-28
RS64845B1 (sr) 2023-12-29
US20190185433A1 (en) 2019-06-20
NO20161297A1 (no) 2007-02-07
MXPA06013405A (es) 2007-03-01
EP1636190A1 (en) 2006-03-22
NO20230913A1 (no) 2007-02-07
EP4299563A2 (en) 2024-01-03
AU2005245296A1 (en) 2005-12-01
ES2388441T3 (es) 2012-10-15
EP3281939A1 (en) 2018-02-14
EP4299563A3 (en) 2024-02-28
CN1956961A (zh) 2007-05-02
EP1636190B1 (en) 2012-06-27
HK1083341A1 (en) 2006-06-30
ES2960824T3 (es) 2024-03-06
US7635704B2 (en) 2009-12-22
NO339223B1 (no) 2016-11-21
TW200600097A (en) 2006-01-01
US20150361044A1 (en) 2015-12-17
HRP20231588T3 (hr) 2024-03-15
JP3754064B2 (ja) 2006-03-08
US20180029989A1 (en) 2018-02-01
PE20120361A1 (es) 2012-05-03
NO347902B1 (no) 2024-05-06
KR20080064909A (ko) 2008-07-09
SI1636190T1 (sl) 2012-09-28
DK3281939T3 (da) 2024-01-22
BRPI0510114B8 (pt) 2021-05-25
HRP20120681T1 (hr) 2012-09-30
NO20200873A1 (no) 2007-02-07
DK1636190T3 (da) 2012-09-24
ZA200610647B (en) 2008-06-25
PL1636190T3 (pl) 2012-10-31
LUC00334I2 (fi) 2024-07-01
EP2514746A1 (en) 2012-10-24
PT3281939T (pt) 2023-11-22
NZ551839A (en) 2009-11-27
TWI329015B (en) 2010-08-21
US20220235009A1 (en) 2022-07-28
HUS2400006I1 (hu) 2024-04-28
JP2006001927A (ja) 2006-01-05
CY1113010T1 (el) 2016-04-13
US20060030710A1 (en) 2006-02-09
BRPI0510114A (pt) 2007-09-25
PE20060358A1 (es) 2006-05-12
PT1636190E (pt) 2012-08-20
AR096100A2 (es) 2015-12-09
EP3281939B1 (en) 2023-10-18
AR049280A1 (es) 2006-07-12

Similar Documents

Publication Publication Date Title
FIC20240008I1 (fi) Elvitegraviiri ja tenofoviirialafenamidi
DE602006013492D1 (de) Verfahren und zwischenprodukte
DE602005018315D1 (de) Rollstuhl
MA28489B1 (fr) Preparations pharmaceutiques
DE602005009811D1 (de) Tetrahydrocarbazole und derivate
DE602005003890D1 (de) Verbinder und Verbinderanordnung
DE502004010641D1 (de) Atemschutzmaske
ATE521769T1 (de) Beschlag
EP1784510A4 (en) IRAK1C SPLICE VARIANT AND USE THEREOF
SE0400476L (sv) Komponent
FI20040750A0 (fi) Prepreg ja sen käyttö
DE102005060186B8 (de) Treppengängiger Rollstuhl
FI20041145A0 (fi) Kaivo ja liitos
SE0400969D0 (sv) Aryl glycine derivatives and their use
FI20050362A0 (fi) Stimulaatiomenetelmä ja ohjelmisto
FI20041562A (fi) Hautausmenetelmä ja tuhkaholvi sen soveltamiseksi
FI6470U1 (fi) Painike ja painike-lukko-yhdistelmä
FI20040873A0 (fi) Koostumus pintojen käsittelyä varten ja sen käyttö
AT501354A3 (de) Atemmaske
SE0402639D0 (sv) Pharmaceutical use
SE0402637D0 (sv) Pharmaceutical use
SE0402638D0 (sv) Pharmaceutical use
SE0402247D0 (sv) Rullstol
FI20041275A0 (fi) Väripartikkeleitä ja niiden valmistus ja käyttö
FI6490U1 (fi) Monipakkaus ja pakkausaihio