FR2320096B2 - - Google Patents

Info

Publication number
FR2320096B2
FR2320096B2 FR7524380A FR7524380A FR2320096B2 FR 2320096 B2 FR2320096 B2 FR 2320096B2 FR 7524380 A FR7524380 A FR 7524380A FR 7524380 A FR7524380 A FR 7524380A FR 2320096 B2 FR2320096 B2 FR 2320096B2
Authority
FR
France
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
FR7524380A
Other languages
French (fr)
Other versions
FR2320096A2 (fr
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
CH Boehringer Sohn AG and Co KG
Original Assignee
CH Boehringer Sohn AG and Co KG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by CH Boehringer Sohn AG and Co KG filed Critical CH Boehringer Sohn AG and Co KG
Publication of FR2320096A2 publication Critical patent/FR2320096A2/fr
Application granted granted Critical
Publication of FR2320096B2 publication Critical patent/FR2320096B2/fr
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/06—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
FR7524380A 1974-08-05 1975-08-05 Nouveaux 2-tetrahydrofurfuryl-6,7-benzomorphanes 5,9-b-disubstitues, leurs sels d'addition avec des acides, leur utilisation comme medicaments et leurs procedes de fabrication Granted FR2320096A2 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE2437610A DE2437610A1 (de) 1974-08-05 1974-08-05 Neue 5,9-beta-disubstituierte 2-tetrahydrofurfuryl-6,7-benzomorphane, deren saeureadditionssalze, ihre verwendung als arzneimittel und verfahren zu deren herstellung

Publications (2)

Publication Number Publication Date
FR2320096A2 FR2320096A2 (fr) 1977-03-04
FR2320096B2 true FR2320096B2 (OSRAM) 1978-09-01

Family

ID=5922448

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7524380A Granted FR2320096A2 (fr) 1974-08-05 1975-08-05 Nouveaux 2-tetrahydrofurfuryl-6,7-benzomorphanes 5,9-b-disubstitues, leurs sels d'addition avec des acides, leur utilisation comme medicaments et leurs procedes de fabrication

Country Status (27)

Country Link
US (1) US3982005A (OSRAM)
JP (1) JPS60358B2 (OSRAM)
AT (1) AT348140B (OSRAM)
BE (1) BE832099R (OSRAM)
BG (3) BG25089A3 (OSRAM)
CA (1) CA1049008A (OSRAM)
CH (7) CH613963A5 (OSRAM)
CS (1) CS189717B2 (OSRAM)
DD (1) DD122685A5 (OSRAM)
DE (1) DE2437610A1 (OSRAM)
DK (1) DK138992C (OSRAM)
ES (6) ES452765A1 (OSRAM)
FI (1) FI63229C (OSRAM)
FR (1) FR2320096A2 (OSRAM)
GB (1) GB1513950A (OSRAM)
HU (1) HU177952B (OSRAM)
IE (1) IE42216B1 (OSRAM)
IL (1) IL47860A (OSRAM)
LU (1) LU73138A1 (OSRAM)
NL (1) NL7509249A (OSRAM)
NO (1) NO143460C (OSRAM)
PH (1) PH13687A (OSRAM)
PL (3) PL99816B1 (OSRAM)
RO (3) RO67390A (OSRAM)
SE (1) SE425392B (OSRAM)
SU (3) SU591147A3 (OSRAM)
ZA (1) ZA754997B (OSRAM)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4087532A (en) * 1974-03-09 1978-05-02 Boehringer Ingelheim Gmbh Analgesically useful 2-tetrahydrofurfuryl-5-lower alkyl-2-oxy-6,7-benzomorphans and salts thereof
GB1575009A (en) * 1976-06-21 1980-09-17 Acf Chemiefarma Nv 6,7-benzomorphan derivatives
DE2716687A1 (de) * 1977-04-15 1978-10-19 Boehringer Sohn Ingelheim 2'-hydroxy-2-(5-isoxazolylmethyl)-6,7benzomorphane, deren saeureadditionssalze und diese enthaltende arzneimittel
NL7804509A (nl) * 1978-04-26 1979-10-30 Acf Chemiefarma Nv Nieuwe 6,7-benzomorfanderivaten en zuuradditiezouten daarvan.
DE2828039A1 (de) * 1978-06-26 1980-01-10 Boehringer Sohn Ingelheim 2-(2-alkoxyethyl)-2'-hydroxy-6,7-benzomorphane deren saeureadditionssalze diese enthaltende arzneimittel und verfahren zu deren herstellung
JPS5636521A (en) * 1979-08-31 1981-04-09 Shin Etsu Chem Co Ltd Production of alkenyloxy group-containing organopolysiloxane
JP5470557B2 (ja) 2007-07-26 2014-04-16 ヴァイティー ファーマシューティカルズ，インコーポレイテッド １１β−ヒドロキシステロイドデヒドロゲナーゼ１型の阻害剤の合成
JP5769970B2 (ja) 2007-11-16 2015-08-26 ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング ベンゾモルファン及び関連骨格のアリール−及びヘテロアリールカルボニル誘導体、かかる化合物を含有する医薬及びこれらの使用
WO2009075835A1 (en) 2007-12-11 2009-06-18 Vitae Pharmaceutical, Inc CYCLIC UREA INHIBITORS OF 11β-HYDROXYSTEROID DEHYDROGENASE 1
TW200934490A (en) 2008-01-07 2009-08-16 Vitae Pharmaceuticals Inc Lactam inhibitors of 11 &abgr;-hydroxysteroid dehydrogenase 1
CA2712500A1 (en) 2008-01-24 2009-07-30 Vitae Pharmaceuticals, Inc. Cyclic carbazate and semicarbazide inhibitors of 11beta-hydroxysteroid dehydrogenase 1
US8598160B2 (en) 2008-02-15 2013-12-03 Vitae Pharmaceuticals, Inc. Cycloalkyl lactame derivatives as inhibitors of 11-beta-hydroxysteroid dehydrogenase 1
KR20110002492A (ko) 2008-05-01 2011-01-07 비타이 파마슈티컬즈, 인코포레이티드 11베타-하이드록시스테로이드 탈수소효소 1의 고리형 억제제
CA2723034A1 (en) 2008-05-01 2009-11-05 Vitae Pharmaceuticals, Inc. Cyclic inhibitors of 11beta-hydroxysteroid dehydrogenase 1
WO2009134392A1 (en) 2008-05-01 2009-11-05 Vitae Pharmaceuticals, Inc. Cyclic inhibitors of 11beta-hydroxysteroid dehydrogenase 1
EP2288596B1 (en) 2008-05-13 2016-11-30 Boehringer Ingelheim International GmbH Alicyclic carboxylic acid derivatives of benzomorphans and related scaffolds, medicaments containing such compounds and their use
EP2324017B1 (en) 2008-07-25 2014-12-31 Boehringer Ingelheim International GmbH INHIBITORS OF 11beta-HYDROXYSTEROID DEHYDROGENASE 1
KR20110050459A (ko) 2008-07-25 2011-05-13 비타이 파마슈티컬즈, 인코포레이티드 11베타-하이드록시스테로이드 탈수소효소 1의 고리형 억제제
US8680093B2 (en) 2009-04-30 2014-03-25 Vitae Pharmaceuticals, Inc. Cyclic inhibitors of 11beta-hydroxysteroid dehydrogenase 1
WO2011011123A1 (en) 2009-06-11 2011-01-27 Vitae Pharmaceuticals, Inc. Cyclic inhibitors of 11beta-hydroxysteroid dehydrogenase 1 based on the 1,3 -oxazinan- 2 -one structure
UY33001A (es) 2009-11-06 2011-05-31 Boehringer Ingelheim Int Derivados arilo y heteroarilcarbonilo de hexahidroindenopiridina y octahidrobenzoquinolina
EP2582698B1 (en) 2010-06-16 2016-09-14 Vitae Pharmaceuticals, Inc. Substituted 5-,6- and 7-membered heterocycles, medicaments containing such compounds, and their use
TWI537258B (zh) 2010-11-05 2016-06-11 百靈佳殷格翰國際股份有限公司 六氫茚并吡啶及八氫苯并喹啉之芳基－及雜環芳基羰基衍生物
WO2013025664A1 (en) 2011-08-17 2013-02-21 Boehringer Ingelheim International Gmbh Indenopyridine derivatives
WO2022113437A1 (ja) 2020-11-26 2022-06-02 信越化学工業株式会社 室温硬化性オルガノポリシロキサン組成物及び物品並びに加水分解性オルガノシラン化合物及びその製造方法
US20240352196A1 (en) 2021-09-03 2024-10-24 Shin-Etsu Chemical Co., Ltd. Organopolysiloxane compound, room temperature-curable organopolysiloxane composition, and article

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE582575A (OSRAM) * 1958-09-22
US3700734A (en) * 1969-01-23 1972-10-24 Merck & Co Inc 2{40 -hydroxy-2,3,5-trimethyl-6,7-benzomorphan
DE2105743C3 (de) * 1971-02-08 1979-11-29 Boehringer Sohn Ingelheim 2-(Furylmethyl)- a -5,9-dialkyl -6,7benzomorphane, Verfahren zu ihrer Herstellung und deren Verwendung
CS166801B2 (OSRAM) * 1971-02-08 1976-03-29 Boehringer Sohn Ingelheim
DE2200596A1 (de) * 1972-01-07 1973-07-12 Boehringer Sohn Ingelheim N-(furyl-methyl)-2'-hydroxy-5-phenyl6,7-benzomorphane, deren saeureadditionssalze sowie verfahren zu deren herstellung
DE2217420C3 (de) * 1972-04-12 1981-03-12 C.H. Boehringer Sohn, 6507 Ingelheim N-Thienylmethyl-Heterocyclen, Verfahren zu deren Herstellung und diese enthaltende pharmazeutische Zubereitungen
DE2229695A1 (de) * 1972-06-19 1974-01-31 Boehringer Sohn Ingelheim 2-(heteroaryl-methyl)-5,9 beta-dialkyl6,7-benzomorphane, deren saeureadditionssalze sowie verfahren zu deren herstellung

Also Published As

Publication number Publication date
FI752211A7 (OSRAM) 1976-02-06
BG25089A3 (bg) 1978-07-12
LU73138A1 (OSRAM) 1977-04-13
JPS60358B2 (ja) 1985-01-07
FI63229B (fi) 1983-01-31
BG25090A3 (bg) 1978-07-12
CH615680A5 (OSRAM) 1980-02-15
SU587858A3 (ru) 1978-01-05
PL99819B1 (pl) 1978-08-31
CH615677A5 (OSRAM) 1980-02-15
CH616420A5 (OSRAM) 1980-03-31
ES452763A1 (es) 1977-10-01
AT348140B (de) 1979-01-25
US3982005A (en) 1976-09-21
DD122685A5 (OSRAM) 1976-10-20
GB1513950A (en) 1978-06-14
JPS5139673A (en) 1976-04-02
RO72736A (ro) 1982-09-09
BG25088A3 (bg) 1978-07-12
HU177952B (en) 1982-02-28
DK138992B (da) 1978-11-27
PH13687A (en) 1980-09-01
RO67390A (ro) 1981-06-30
ES452768A1 (es) 1977-10-01
IE42216L (en) 1976-02-05
FR2320096A2 (fr) 1977-03-04
NO143460B (no) 1980-11-10
NO752731L (OSRAM) 1976-02-06
IL47860A (en) 1979-01-31
DK138992C (da) 1979-04-30
ES452764A1 (es) 1977-10-16
SU591147A3 (ru) 1978-01-30
ZA754997B (en) 1977-04-27
CS189717B2 (en) 1979-04-30
ES452767A1 (es) 1977-10-01
NO143460C (no) 1981-02-18
ES452765A1 (es) 1977-10-16
IL47860A0 (en) 1975-11-25
CH616421A5 (OSRAM) 1980-03-31
DE2437610A1 (de) 1976-02-26
RO72735A (ro) 1982-09-09
CH615678A5 (OSRAM) 1980-02-15
PL99838B1 (pl) 1978-08-31
FI63229C (fi) 1983-05-10
AU8364675A (en) 1977-02-10
SE7508789L (sv) 1976-02-10
ATA523775A (de) 1978-06-15
ES452766A1 (es) 1977-10-01
CH613963A5 (OSRAM) 1979-10-31
NL7509249A (nl) 1976-02-09
CA1049008A (en) 1979-02-20
DK352875A (da) 1976-02-06
SE425392B (sv) 1982-09-27
IE42216B1 (en) 1980-07-02
PL99816B1 (pl) 1978-08-31
CH615679A5 (OSRAM) 1980-02-15
SU587859A3 (ru) 1978-01-05
BE832099R (fr) 1976-02-04

Similar Documents

Publication Publication Date Title
FR2320096B2 (OSRAM)
FR2258143B1 (OSRAM)
FR2258641A1 (OSRAM)
FR2256227A2 (OSRAM)
DK136405C (OSRAM)
FR2256966A1 (OSRAM)
DK137896C (OSRAM)
DK140150C (OSRAM)
DK244874A (OSRAM)
CS176555B1 (OSRAM)
CS176319B1 (OSRAM)
BG20475A1 (OSRAM)
DD114778A1 (OSRAM)
DD113243A1 (OSRAM)
DD122194A5 (OSRAM)
CH602095A5 (OSRAM)
CH600418B5 (OSRAM)
CH594378A5 (OSRAM)
CH589747B5 (OSRAM)
CH589385A5 (OSRAM)
DD122579A5 (OSRAM)
BG20473A1 (OSRAM)
BG20471A1 (OSRAM)
BG20462A1 (OSRAM)
BG20455A1 (OSRAM)