FI970393A7 - (-)-(3R)-3-metyyli-4-(4-(4-(4-pyridyyli)piperatsin-1-yyli)fenoksi)voih appo soluadheesioinhibiittoreina - Google Patents

(-)-(3R)-3-metyyli-4-(4-(4-(4-pyridyyli)piperatsin-1-yyli)fenoksi)voih appo soluadheesioinhibiittoreina Download PDF

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Publication number
FI970393A7
FI970393A7 FI970393A FI970393A FI970393A7 FI 970393 A7 FI970393 A7 FI 970393A7 FI 970393 A FI970393 A FI 970393A FI 970393 A FI970393 A FI 970393A FI 970393 A7 FI970393 A7 FI 970393A7
Authority
FI
Finland
Prior art keywords
piperazin
phenoxy
pyridyl
methyl
butyric acid
Prior art date
Application number
FI970393A
Other languages
English (en)
Finnish (fi)
Swedish (sv)
Other versions
FI970393A0 (fi
FI970393L (fi
Inventor
Stuart Dennett Mills
Original Assignee
Zeneca Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US08/457,538 external-priority patent/US5652242A/en
Priority claimed from GBGB9518188.9A external-priority patent/GB9518188D0/en
Application filed by Zeneca Ltd filed Critical Zeneca Ltd
Publication of FI970393A0 publication Critical patent/FI970393A0/fi
Publication of FI970393L publication Critical patent/FI970393L/fi
Publication of FI970393A7 publication Critical patent/FI970393A7/fi

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/72—Nitrogen atoms
    • C07D213/74—Amino or imino radicals substituted by hydrocarbon or substituted hydrocarbon radicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Diabetes (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Hematology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyridine Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
FI970393A 1995-06-01 1996-05-28 (-)-(3R)-3-metyyli-4-(4-(4-(4-pyridyyli)piperatsin-1-yyli)fenoksi)voih appo soluadheesioinhibiittoreina FI970393A7 (fi)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US08/457,538 US5652242A (en) 1993-03-29 1995-06-01 Heterocyclic derivatives
GBGB9518188.9A GB9518188D0 (en) 1995-09-07 1995-09-07 Optically active derivative
PCT/GB1996/001260 WO1996038416A1 (en) 1995-06-01 1996-05-28 (-)-(3r)-3-methyl-4-{4-[4-(4-pyridyl)piperazin-1-yl]phenoxy} butyric acid as cellular adhesion inhibitor

Publications (3)

Publication Number Publication Date
FI970393A0 FI970393A0 (fi) 1997-01-30
FI970393L FI970393L (fi) 1997-01-30
FI970393A7 true FI970393A7 (fi) 1997-01-30

Family

ID=26307696

Family Applications (1)

Application Number Title Priority Date Filing Date
FI970393A FI970393A7 (fi) 1995-06-01 1996-05-28 (-)-(3R)-3-metyyli-4-(4-(4-(4-pyridyyli)piperatsin-1-yyli)fenoksi)voih appo soluadheesioinhibiittoreina

Country Status (31)

Country Link
EP (1) EP0796247A1 (de)
JP (1) JP2885941B2 (de)
KR (1) KR100245957B1 (de)
AT (1) AT406675B (de)
AU (1) AU710105B2 (de)
BE (1) BE1009520A5 (de)
BR (1) BR9606409A (de)
CA (1) CA2194397A1 (de)
CH (1) CH691808A5 (de)
CZ (1) CZ26997A3 (de)
DE (1) DE19680509T1 (de)
DK (1) DK10697A (de)
ES (1) ES2137886B1 (de)
FI (1) FI970393A7 (de)
GB (1) GB2304340B (de)
GR (1) GR1002702B (de)
HU (1) HUP9700274A3 (de)
IE (1) IE960405A1 (de)
IL (1) IL118477A0 (de)
IT (1) IT1290839B1 (de)
LU (1) LU90008B1 (de)
MC (1) MC2418A1 (de)
MX (1) MX9700379A (de)
NL (1) NL1003243C2 (de)
NO (1) NO307460B1 (de)
NZ (1) NZ308597A (de)
PL (1) PL318440A1 (de)
SE (1) SE510812C2 (de)
SK (1) SK13097A3 (de)
TR (1) TR199700020T1 (de)
WO (1) WO1996038416A1 (de)

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0100158A3 (de) * 1982-07-28 1985-03-27 The Upjohn Company (3-Pyridinyl)-heteroalkarylalkanole, ihre Alkansäuren und ihre Ester
GB8609630D0 (en) * 1986-04-19 1986-05-21 Pfizer Ltd Anti-arrhythmia agents
EP0690847A1 (de) * 1993-03-29 1996-01-10 Zeneca Limited Heterozyklische derivate als plätchenaggregationsinhibitoren
EP0691959B1 (de) * 1993-03-29 1998-07-22 Zeneca Limited Heterozyklische derivate als plätchenaggregationsinhibitoren

Also Published As

Publication number Publication date
ES2137886B1 (es) 2000-08-16
GB2304340A (en) 1997-03-19
NZ308597A (en) 1998-11-25
MC2418A1 (fr) 1997-05-23
LU90008B1 (fr) 1997-04-16
NO970437D0 (no) 1997-01-31
NO307460B1 (no) 2000-04-10
HU9700274D0 (en) 1997-04-28
CH691808A5 (de) 2001-10-31
FI970393A0 (fi) 1997-01-30
EP0796247A1 (de) 1997-09-24
CZ26997A3 (en) 1997-08-13
WO1996038416A1 (en) 1996-12-05
ATA900596A (de) 1999-12-15
CA2194397A1 (en) 1996-12-05
HUP9700274A3 (en) 2000-02-28
JP2885941B2 (ja) 1999-04-26
SE510812C2 (sv) 1999-06-28
FI970393L (fi) 1997-01-30
DE19680509T1 (de) 1997-12-04
GB9627127D0 (en) 1997-02-19
GR1002702B (el) 1997-05-22
TR199700020T1 (tr) 1997-04-22
SK13097A3 (en) 1997-08-06
DK10697A (da) 1997-04-01
KR100245957B1 (ko) 2000-04-01
JPH09512836A (ja) 1997-12-22
PL318440A1 (en) 1997-06-09
BR9606409A (pt) 1997-09-30
HUP9700274A2 (hu) 1999-06-28
NL1003243C2 (nl) 1996-12-04
AU710105B2 (en) 1999-09-16
AT406675B (de) 2000-07-25
AU5827296A (en) 1996-12-18
IL118477A0 (en) 1996-09-12
ES2137886A1 (es) 1999-12-16
BE1009520A5 (fr) 1997-04-01
ITMI961113A1 (it) 1997-12-01
IT1290839B1 (it) 1998-12-14
SE9700203L (sv) 1997-01-24
SE9700203D0 (sv) 1997-01-24
ITMI961113A0 (it) 1996-05-31
KR970704689A (ko) 1997-09-06
MX9700379A (es) 1997-04-30
NO970437L (no) 1997-02-20
IE960405A1 (en) 1996-12-11
GB2304340B (en) 1998-07-29

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