FI90549B - Makrolidföreningar och användning av dem vid bekämpning av skadekryp - Google Patents

Makrolidföreningar och användning av dem vid bekämpning av skadekryp Download PDF

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Publication number
FI90549B
FI90549B FI923445A FI923445A FI90549B FI 90549 B FI90549 B FI 90549B FI 923445 A FI923445 A FI 923445A FI 923445 A FI923445 A FI 923445A FI 90549 B FI90549 B FI 90549B
Authority
FI
Finland
Prior art keywords
formula
compounds
group
compound
ethyl acetate
Prior art date
Application number
FI923445A
Other languages
English (en)
Finnish (fi)
Other versions
FI923445A (sv
FI923445A0 (sv
FI90549C (sv
Inventor
Neil Porter
David Noble
Derek R Sutherland
Michael V J Ramsay
Edward P Tiley
Oswy Z Pereira
John B Ward
Hazel M Noble
Richard A Fletton
Original Assignee
American Cyanamid Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB868613790A external-priority patent/GB8613790D0/en
Priority claimed from GB868625854A external-priority patent/GB8625854D0/en
Priority claimed from GB878708423A external-priority patent/GB8708423D0/en
Application filed by American Cyanamid Co filed Critical American Cyanamid Co
Publication of FI923445A publication Critical patent/FI923445A/sv
Publication of FI923445A0 publication Critical patent/FI923445A0/sv
Application granted granted Critical
Publication of FI90549B publication Critical patent/FI90549B/sv
Publication of FI90549C publication Critical patent/FI90549C/sv

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
    • C07D493/22—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains four or more hetero rings
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
    • A01N43/90—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having two or more relevant hetero rings, condensed among themselves or with a common carbocyclic ring system
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N49/00—Biocides, pest repellants or attractants, or plant growth regulators, containing compounds containing the group, wherein m+n>=1, both X together may also mean —Y— or a direct carbon-to-carbon bond, and the carbon atoms marked with an asterisk are not part of any ring system other than that which may be formed by the atoms X, the carbon atoms in square brackets being part of any acyclic or cyclic structure, or the group, wherein A means a carbon atom or Y, n>=0, and not more than one of these carbon atoms being a member of the same ring system, e.g. juvenile insect hormones or mimics thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/01—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing oxygen

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Dentistry (AREA)
  • Plant Pathology (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Environmental Sciences (AREA)
  • Pest Control & Pesticides (AREA)
  • Agronomy & Crop Science (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Molecular Biology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Insects & Arthropods (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Saccharide Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Claims (4)

1. Makrolidförening med formeln
5 NOR2 CH, H I 3 H rfiT- ft 0\J « .. CH-.
15. O f 3 ,..4 «k-Jj. a i 10 c»3 [\« \ pi (I) H 'H °vr° ΊΙ phJ^>h 15 0_4 JL rf^Cli3 H I 3 OR vari R1 är metyl, etyl eller isopropyl;
20 R2 är väte, lägre alkyl eller allyl och grupp =NOR2 före-ligger i E-konfiguration; och OR3 är en hydroxylgrupp eller en grupp -OR4, -OCOR4 eller -0C02R4, väri R4 är lägre alkyl, eller en grupp -OCONR8R9, väri R8 och R9 vardera självständigt är väte eller lägre 25 alkyl.
2. Makrolidförening enligt patentkrav 1, k ä n -netecknat därav, att R1 är isopropyl, R2 är metyl och R3 är väte.
3. Användning av en makrolidförening enligt patent-30 krav 1 för bekämpande av skadekryp i lantbruk, trädgärds- odling eller skogsskötsel eller i butiker, byggnader eller andra allmänna platser eller livsmiljöer för skadekryp.
4. Användning enligt patentkrav 3, känne-t e c k n a d därav, att skadekrypen är insekter, kvals- 35 ter eller spolmaskar.
FI923445A 1986-06-06 1992-07-30 Makrolidföreningar och användning av dem vid bekämpning av skadekryp FI90549C (sv)

Applications Claiming Priority (8)

Application Number Priority Date Filing Date Title
GB8613790 1986-06-06
GB868613790A GB8613790D0 (en) 1986-06-06 1986-06-06 Chemical compounds
GB8625854 1986-10-29
GB868625854A GB8625854D0 (en) 1986-10-29 1986-10-29 Chemical process
GB878708423A GB8708423D0 (en) 1987-04-08 1987-04-08 Chemical compounds
GB8708423 1987-04-08
FI872517 1987-06-04
FI872517A FI90663C (sv) 1986-06-06 1987-06-04 Förfarande för framställning av terapeutiskt användbara makrolidföreningar

Publications (4)

Publication Number Publication Date
FI923445A FI923445A (sv) 1992-07-30
FI923445A0 FI923445A0 (sv) 1992-07-30
FI90549B true FI90549B (sv) 1993-11-15
FI90549C FI90549C (sv) 1994-02-25

Family

ID=27263057

Family Applications (2)

Application Number Title Priority Date Filing Date
FI872517A FI90663C (sv) 1986-06-06 1987-06-04 Förfarande för framställning av terapeutiskt användbara makrolidföreningar
FI923445A FI90549C (sv) 1986-06-06 1992-07-30 Makrolidföreningar och användning av dem vid bekämpning av skadekryp

Family Applications Before (1)

Application Number Title Priority Date Filing Date
FI872517A FI90663C (sv) 1986-06-06 1987-06-04 Förfarande för framställning av terapeutiskt användbara makrolidföreningar

Country Status (35)

Country Link
US (1) US4900753A (sv)
JP (1) JP2648147B2 (sv)
KR (1) KR950010077B1 (sv)
CN (1) CN1023858C (sv)
AR (1) AR244691A1 (sv)
AT (1) AT398571B (sv)
AU (1) AU609399B2 (sv)
BE (1) BE1000201A4 (sv)
BR (1) BR8702866A (sv)
CA (1) CA1296329C (sv)
CH (1) CH677670A5 (sv)
DE (3) DE3745133C2 (sv)
DK (1) DK166498B1 (sv)
EG (1) EG18752A (sv)
ES (1) ES2006479A6 (sv)
FI (2) FI90663C (sv)
FR (1) FR2599742B1 (sv)
GB (1) GB2192630B (sv)
GE (1) GEP19981388B (sv)
GR (1) GR870891B (sv)
HU (1) HU199847B (sv)
IE (1) IE60411B1 (sv)
IL (1) IL82776A (sv)
IT (1) IT1206015B (sv)
LU (2) LU86908A1 (sv)
LV (2) LV10280A (sv)
NL (2) NL193376C (sv)
NZ (1) NZ220587A (sv)
OA (1) OA08606A (sv)
PH (1) PH23948A (sv)
PL (3) PL153036B1 (sv)
PT (1) PT85018B (sv)
SE (1) SE503399C2 (sv)
TR (1) TR28970A (sv)
UA (1) UA45300C2 (sv)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4886828A (en) * 1986-09-12 1989-12-12 American Cyanamid Company Δ22 -derivatives of LL-F28249 compounds
EP0260537A1 (en) * 1986-09-12 1988-03-23 American Cyanamid Company 13-Deoxy-23-oxo(keto) and 23-imino derivatives of 13-deoxy C-076-aglycone compounds
ES2058082T3 (es) * 1986-09-12 1994-11-01 American Cyanamid Co Derivados 23-oxo (ceto) y 23-imino de compuestos ll-f28249.
GB8721377D0 (en) * 1987-09-11 1987-10-21 Glaxo Group Ltd Chemical compounds
GB8811036D0 (en) * 1988-05-10 1988-06-15 Glaxo Group Ltd Chemical compounds
GB8813150D0 (en) * 1988-06-03 1988-07-06 American Cyanamid Co Chemical compounds
GB8905605D0 (en) * 1989-03-11 1989-04-26 Beecham Group Plc Novel compounds
NZ233680A (en) * 1989-05-17 1995-02-24 Beecham Group Plc Avermectins and milbemycins and compositions thereof
US4988824A (en) * 1989-09-11 1991-01-29 Maulding Donald R Process for the preparation of 23-(C1-C6 alkyloxime)-LL-F28249 compounds
CA2097918C (en) * 1990-12-07 2002-07-16 Frank N. Chang Stabilized insect nematode compositions
JP2855181B2 (ja) 1993-12-10 1999-02-10 敏雄 鈴木 松類の枯損防止用組成物及び防止方法
EP1197215B1 (en) 2000-10-10 2006-03-22 Wyeth Anthelmintic compositions
US7348417B2 (en) * 2003-08-07 2008-03-25 Wyeth Method of purifying moxidectin through crystallization
WO2006119174A1 (en) * 2005-04-30 2006-11-09 Ocular Surface Center, P.A. Method for treating ocular demodex
JP4939025B2 (ja) * 2005-09-30 2012-05-23 三菱電線工業株式会社 電熱ヒータ付きハンドル用グリップ部材
EP1849363A1 (en) * 2006-03-09 2007-10-31 Cheminova A/S Synergistic combination of glutamate- and GABA-gated chloride agonist pesticide and at least one of Vitamin E or Niacin
US8128968B2 (en) 2007-08-29 2012-03-06 Tissuetech, Inc. Compositions and methods for treating Demodex infestations
ES2659159T3 (es) * 2011-12-02 2018-03-14 Merial, Inc. Formulaciones de moxidectina inyectable de acción prolongada y nuevas formas cristalinas de moxidectina
FR2995605B1 (fr) * 2012-09-18 2014-09-19 Sanofi Sa Derives de macrolides, leur preparation et leur application therapeutique.

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PH15982A (en) * 1977-10-03 1983-05-18 Merck & Co Inc Selective hydrogenation producta of c-076 compounds and derivatives thereof
US4289760A (en) * 1980-05-02 1981-09-15 Merck & Co., Inc. 23-Keto derivatives of C-076 compounds
US4423209A (en) * 1982-02-26 1983-12-27 Merck & Co., Inc. Processes for the interconversion of avermectin compounds
JPS59108785A (ja) * 1982-11-25 1984-06-23 Sankyo Co Ltd ミルベマイシン類の５−オキシム誘導体
JPS60126289A (ja) * 1983-11-14 1985-07-05 Sankyo Co Ltd ミルベマイシン類の５−カ−ボネ−ト誘導体
DK165119C (da) * 1984-06-05 1993-03-01 American Cyanamid Co Antibiotiske forbindelser betegnet ll-f28249alfa, beta, gamma, delta, epsilon, zeta, eta, theta, iota, kappa, my og ny og pharmaceutisk or pharmakologisk acceptable salte deraf samt fremgangsmaade til deres fremstilling
US4579864A (en) * 1984-06-11 1986-04-01 Merck & Co., Inc. Avermectin and milbemycin 13-keto, 13-imino and 13-amino derivatives
IE59394B1 (en) * 1984-09-14 1994-02-23 American Cyanamid Co Antibiotic compounds and their preparation
ES8802229A1 (es) * 1985-04-30 1988-04-16 Glaxo Group Ltd Un procedimiento para preparar nuevos derivados lactonicos macrociclicos.
ES2058082T3 (es) * 1986-09-12 1994-11-01 American Cyanamid Co Derivados 23-oxo (ceto) y 23-imino de compuestos ll-f28249.

Also Published As

Publication number Publication date
FI923445A (sv) 1992-07-30
FR2599742B1 (fr) 1989-05-19
IE871496L (en) 1987-12-06
DK290287D0 (da) 1987-06-04
ES2006479A6 (es) 1989-05-01
FI872517A0 (sv) 1987-06-04
BR8702866A (pt) 1988-03-01
SE503399C2 (sv) 1996-06-10
FI872517A (sv) 1987-12-07
CN1023858C (zh) 1994-02-23
CH677670A5 (sv) 1991-06-14
KR880000441A (ko) 1988-03-25
FI923445A0 (sv) 1992-07-30
DE3745133C2 (de) 1998-01-02
UA45300C2 (uk) 2002-04-15
CN87104431A (zh) 1987-12-30
GEP19981388B (en) 1998-11-10
HUT44254A (en) 1988-02-29
LV10781B (en) 1996-10-20
ATA143887A (de) 1994-05-15
PT85018A (en) 1987-07-01
JP2648147B2 (ja) 1997-08-27
IL82776A0 (en) 1987-12-20
GR870891B (en) 1987-10-02
GB2192630A (en) 1988-01-20
DE19875029I2 (de) 2001-11-22
US4900753A (en) 1990-02-13
LV10781A (lv) 1995-08-20
SE8702361D0 (sv) 1987-06-05
FI90549C (sv) 1994-02-25
SE8702361L (sv) 1987-12-07
PH23948A (en) 1990-01-23
PL266100A1 (en) 1988-07-21
LU88790I2 (fr) 1997-03-18
CA1296329C (en) 1992-02-25
FI90663C (sv) 1994-03-10
LV10280A (lv) 1994-10-20
GB8713239D0 (en) 1987-07-08
FR2599742A1 (fr) 1987-12-11
EG18752A (en) 1993-12-30
GB2192630B (en) 1990-05-23
JPS6354375A (ja) 1988-03-08
PL153036B1 (en) 1991-02-28
BE1000201A4 (fr) 1988-08-23
PT85018B (pt) 1990-03-08
NL193376B (nl) 1999-04-01
IE60411B1 (en) 1994-07-13
IT1206015B (it) 1989-04-05
LU86908A1 (fr) 1988-01-20
DE3718926A1 (de) 1987-12-10
FI90663B (sv) 1993-11-30
AU609399B2 (en) 1991-05-02
IL82776A (en) 1992-02-16
NL8701322A (nl) 1988-01-04
PL155723B1 (en) 1991-12-31
NZ220587A (en) 1990-05-28
DK166498B1 (da) 1993-06-01
AT398571B (de) 1994-12-27
NL990026I2 (nl) 1999-12-01
TR28970A (tr) 1997-07-21
NL990026I1 (nl) 1999-11-01
KR950010077B1 (ko) 1995-09-06
OA08606A (en) 1988-11-30
DK290287A (da) 1987-12-07
IT8748023A0 (it) 1987-06-05
PL153226B1 (en) 1991-03-29
DE3718926C2 (de) 1998-01-15
HU199847B (en) 1990-03-28
NL193376C (nl) 1999-08-03
AU7387387A (en) 1987-12-10
AR244691A1 (es) 1993-11-30

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