FR2995605B1 - Derives de macrolides, leur preparation et leur application therapeutique. - Google Patents

Derives de macrolides, leur preparation et leur application therapeutique.

Info

Publication number
FR2995605B1
FR2995605B1 FR1258744A FR1258744A FR2995605B1 FR 2995605 B1 FR2995605 B1 FR 2995605B1 FR 1258744 A FR1258744 A FR 1258744A FR 1258744 A FR1258744 A FR 1258744A FR 2995605 B1 FR2995605 B1 FR 2995605B1
Authority
FR
France
Prior art keywords
preparation
therapeutic application
macrolide derivatives
macrolide
derivatives
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
FR1258744A
Other languages
English (en)
Other versions
FR2995605A1 (fr
Inventor
Nicolas Baurin
Yannick Benedetti
Emmanuel Bouley
Jidong Zhang
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sanofi SA
Original Assignee
Sanofi SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to FR1258744A priority Critical patent/FR2995605B1/fr
Application filed by Sanofi SA filed Critical Sanofi SA
Priority to KR1020157008511A priority patent/KR20150056569A/ko
Priority to PL13776739T priority patent/PL2897970T3/pl
Priority to NZ706393A priority patent/NZ706393A/en
Priority to DK13776739.8T priority patent/DK2897970T3/en
Priority to CA2884909A priority patent/CA2884909A1/fr
Priority to UAA201503646A priority patent/UA114003C2/uk
Priority to BR112015005560A priority patent/BR112015005560A2/pt
Priority to EP13776739.8A priority patent/EP2897970B1/fr
Priority to JP2015531594A priority patent/JP6231107B2/ja
Priority to CN201380060052.1A priority patent/CN104797588B/zh
Priority to PE2015000376A priority patent/PE20150653A1/es
Priority to HUE13776739A priority patent/HUE029841T2/en
Priority to AU2013320407A priority patent/AU2013320407A1/en
Priority to PT137767398T priority patent/PT2897970T/pt
Priority to PCT/EP2013/069185 priority patent/WO2014044645A1/fr
Priority to SG11201501765YA priority patent/SG11201501765YA/en
Priority to MX2015003503A priority patent/MX2015003503A/es
Priority to EA201590594A priority patent/EA027177B1/ru
Priority to ES13776739.8T priority patent/ES2598079T3/es
Priority to SI201330326A priority patent/SI2897970T1/sl
Publication of FR2995605A1 publication Critical patent/FR2995605A1/fr
Publication of FR2995605B1 publication Critical patent/FR2995605B1/fr
Application granted granted Critical
Priority to IL237593A priority patent/IL237593A/en
Priority to ZA2015/01597A priority patent/ZA201501597B/en
Priority to PH12015500527A priority patent/PH12015500527A1/en
Priority to TNP2015000095A priority patent/TN2015000095A1/fr
Priority to US14/658,752 priority patent/US20150210729A1/en
Priority to DO2015000062A priority patent/DOP2015000062A/es
Priority to CL2015000659A priority patent/CL2015000659A1/es
Priority to CR20150160A priority patent/CR20150160A/es
Priority to MA37999A priority patent/MA37999B1/fr
Priority to HK15109737.2A priority patent/HK1209127A1/xx
Priority to HRP20161184TT priority patent/HRP20161184T1/hr
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/26—Acyclic or carbocyclic radicals, substituted by hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A61P31/06—Antibacterial agents for tuberculosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A61P31/08—Antibacterial agents for leprosy
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H1/00—Processes for the preparation of sugar derivatives

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Pulmonology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Epoxy Compounds (AREA)
FR1258744A 2012-09-18 2012-09-18 Derives de macrolides, leur preparation et leur application therapeutique. Active FR2995605B1 (fr)

Priority Applications (32)

Application Number Priority Date Filing Date Title
FR1258744A FR2995605B1 (fr) 2012-09-18 2012-09-18 Derives de macrolides, leur preparation et leur application therapeutique.
ES13776739.8T ES2598079T3 (es) 2012-09-18 2013-09-16 Derivados de macrólidos, su preparación y su uso terapéutico
MX2015003503A MX2015003503A (es) 2012-09-18 2013-09-16 Derivados de macrolidos, su preparacion y su uso terapeutico.
PL13776739T PL2897970T3 (pl) 2012-09-18 2013-09-16 Pochodne makrolidów, ich wytwarzanie i zastosowanie terapeutyczne
CA2884909A CA2884909A1 (fr) 2012-09-18 2013-09-16 Derives de macrolide, leur preparation et leur utilisation therapeutique
UAA201503646A UA114003C2 (xx) 2012-09-18 2013-09-16 Макролідні похідні, спосіб їх одержання та їх терапевтичне застосуваня
BR112015005560A BR112015005560A2 (pt) 2012-09-18 2013-09-16 derivados de macrolídeos, sua preparação e seu uso terapêutico
EP13776739.8A EP2897970B1 (fr) 2012-09-18 2013-09-16 Dérivés de macrolide, leur préparation et leur utilisation thérapeutique
JP2015531594A JP6231107B2 (ja) 2012-09-18 2013-09-16 マクロライド誘導体、その製造およびその治療的使用
CN201380060052.1A CN104797588B (zh) 2012-09-18 2013-09-16 大环内酯衍生物、其制备及其治疗用途
PE2015000376A PE20150653A1 (es) 2012-09-18 2013-09-16 Derivados de macrolidos, su preparacion y su uso terapeutico
HUE13776739A HUE029841T2 (en) 2012-09-18 2013-09-16 Macrolide derivatives, their preparation and their therapeutic use
AU2013320407A AU2013320407A1 (en) 2012-09-18 2013-09-16 Macrolide derivatives, preparation thereof and therapeutic use thereof
PT137767398T PT2897970T (pt) 2012-09-18 2013-09-16 Derivados de macrólidos, sua preparação e utilização terapêutica
PCT/EP2013/069185 WO2014044645A1 (fr) 2012-09-18 2013-09-16 Dérivés de macrolide, leur préparation et leur utilisation thérapeutique
SG11201501765YA SG11201501765YA (en) 2012-09-18 2013-09-16 Macrolide derivatives, preparation thereof and therapeutic use thereof
KR1020157008511A KR20150056569A (ko) 2012-09-18 2013-09-16 마크롤라이드 유도체, 이의 제조 및 이의 치료적 용도
DK13776739.8T DK2897970T3 (en) 2012-09-18 2013-09-16 MACROLIDE DERIVATIVES, PREPARING thereof, AND THERAPEUTIC APPLICATION
EA201590594A EA027177B1 (ru) 2012-09-18 2013-09-16 Макролидные производные, их получение и их терапевтическое использование
SI201330326A SI2897970T1 (sl) 2012-09-18 2013-09-16 Derivati makrolida, njihova priprava in terapevtska uporaba
NZ706393A NZ706393A (en) 2012-09-18 2013-09-16 Macrolide derivatives, preparation thereof and therapeutic use thereof
IL237593A IL237593A (en) 2012-09-18 2015-03-05 Macrolide derivatives, ways of preparing them and their use of thyrapoites
ZA2015/01597A ZA201501597B (en) 2012-09-18 2015-03-09 Macrolide derivatives,preparation thereof and therapeutic use thereof
PH12015500527A PH12015500527A1 (en) 2012-09-18 2015-03-11 Macrolide derivatives, preparation and therapeutic use thereof
TNP2015000095A TN2015000095A1 (en) 2012-09-18 2015-03-13 Macrolide derivatives, preparation thereof and therapeutic use thereof
US14/658,752 US20150210729A1 (en) 2012-09-18 2015-03-16 Macrolide derivatives, preparation thereof and therapeutic use thereof
DO2015000062A DOP2015000062A (es) 2012-09-18 2015-03-16 Derivados de macrólidos, su preparación y su uso terapéutico
CL2015000659A CL2015000659A1 (es) 2012-09-18 2015-03-17 Compuestos derivados de macrólidos; proceso de preparación; composicion farmaceutica; y su uso en el tratamiento y/o prevencion de infecciones bacterianas.
CR20150160A CR20150160A (es) 2012-09-18 2015-03-20 Derivados de macrólidos, su preparación y su uso terapéutico
MA37999A MA37999B1 (fr) 2012-09-18 2015-04-12 Dérivés de macrolide, leur préparation et leur utilisation thérapeutique
HK15109737.2A HK1209127A1 (en) 2012-09-18 2015-10-06 Macrolide derivatives, preparation thereof and therapeutic use thereof
HRP20161184TT HRP20161184T1 (hr) 2012-09-18 2016-09-15 Derivati makrolida, njihovo pripremanje i njihova terapijska upotreba

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR1258744A FR2995605B1 (fr) 2012-09-18 2012-09-18 Derives de macrolides, leur preparation et leur application therapeutique.

Publications (2)

Publication Number Publication Date
FR2995605A1 FR2995605A1 (fr) 2014-03-21
FR2995605B1 true FR2995605B1 (fr) 2014-09-19

Family

ID=47178173

Family Applications (1)

Application Number Title Priority Date Filing Date
FR1258744A Active FR2995605B1 (fr) 2012-09-18 2012-09-18 Derives de macrolides, leur preparation et leur application therapeutique.

Country Status (32)

Country Link
US (1) US20150210729A1 (fr)
EP (1) EP2897970B1 (fr)
JP (1) JP6231107B2 (fr)
KR (1) KR20150056569A (fr)
CN (1) CN104797588B (fr)
AU (1) AU2013320407A1 (fr)
BR (1) BR112015005560A2 (fr)
CA (1) CA2884909A1 (fr)
CL (1) CL2015000659A1 (fr)
CR (1) CR20150160A (fr)
DK (1) DK2897970T3 (fr)
DO (1) DOP2015000062A (fr)
EA (1) EA027177B1 (fr)
ES (1) ES2598079T3 (fr)
FR (1) FR2995605B1 (fr)
HK (1) HK1209127A1 (fr)
HR (1) HRP20161184T1 (fr)
HU (1) HUE029841T2 (fr)
IL (1) IL237593A (fr)
MA (1) MA37999B1 (fr)
MX (1) MX2015003503A (fr)
NZ (1) NZ706393A (fr)
PE (1) PE20150653A1 (fr)
PH (1) PH12015500527A1 (fr)
PL (1) PL2897970T3 (fr)
PT (1) PT2897970T (fr)
SG (1) SG11201501765YA (fr)
SI (1) SI2897970T1 (fr)
TN (1) TN2015000095A1 (fr)
UA (1) UA114003C2 (fr)
WO (1) WO2014044645A1 (fr)
ZA (1) ZA201501597B (fr)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2019020759A1 (fr) 2017-07-26 2019-01-31 Sanofi Macrolides de séquanamycine utiles dans le traitement de la tuberculose
WO2019020763A1 (fr) 2017-07-26 2019-01-31 Sanofi Macrolides de séquanamycine utiles dans le traitement de la tuberculose
WO2019020767A1 (fr) 2017-07-26 2019-01-31 Sanofi Macrolides de séquanamycine utiles dans le traitement de la tuberculose

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3674773A (en) * 1970-10-06 1972-07-04 Abbott Lab Erythromycin derivatives
FR2126108B1 (fr) * 1971-02-25 1974-08-02 Rhone Poulenc Sa
CN85103264A (zh) * 1984-04-13 1987-01-14 美国辉瑞有限公司 9a-氮杂-9a-高红霉素衍生物
US4585759A (en) * 1985-01-22 1986-04-29 Pfizer Inc. Antibacterial derivatives of a neutral macrolide
CA1296329C (fr) * 1986-06-06 1992-02-25 Derek R. Sutherland Composes de type macrolide
US4920102A (en) * 1988-04-18 1990-04-24 Eli Lilly And Company Method for treating gastrointestinal disorders
JPH05117291A (ja) * 1991-09-20 1993-05-14 Yamanouchi Pharmaceut Co Ltd 新規マクロライド誘導体
TW226373B (fr) * 1992-07-15 1994-07-11 Pfizer
US6043227A (en) * 1998-08-19 2000-03-28 Pfizer Inc. C11 carbamates of macrolide antibacterials
MXPA04003026A (es) * 2001-11-07 2004-07-05 Aventis Pharma Gmbh Metodo para la produccion de desclaritromicina, y productos intermedios.
GB0310980D0 (en) * 2003-05-13 2003-06-18 Glaxo Group Ltd Novel compounds
CN101115764B (zh) * 2005-02-09 2012-09-26 巴斯利尔药物股份公司 大环内酯类化合物
TW200914020A (en) 2007-08-28 2009-04-01 Lilly Co Eli Substituted piperazinyl pyrazines and pyridines as 5-HT7 receptor antagonists

Also Published As

Publication number Publication date
KR20150056569A (ko) 2015-05-26
CN104797588B (zh) 2017-10-20
EP2897970A1 (fr) 2015-07-29
PH12015500527B1 (en) 2015-04-27
BR112015005560A2 (pt) 2017-07-04
CN104797588A (zh) 2015-07-22
NZ706393A (en) 2018-07-27
HRP20161184T1 (hr) 2016-11-04
JP2015528485A (ja) 2015-09-28
CA2884909A1 (fr) 2014-03-27
SG11201501765YA (en) 2015-04-29
TN2015000095A1 (en) 2016-06-29
PT2897970T (pt) 2016-10-25
ES2598079T3 (es) 2017-01-25
MA37999B1 (fr) 2016-12-30
EA201590594A1 (ru) 2015-07-30
WO2014044645A1 (fr) 2014-03-27
SI2897970T1 (sl) 2016-11-30
JP6231107B2 (ja) 2017-11-15
EP2897970B1 (fr) 2016-07-13
UA114003C2 (xx) 2017-04-10
PE20150653A1 (es) 2015-05-26
EA027177B1 (ru) 2017-06-30
HK1209127A1 (en) 2016-03-24
PH12015500527A1 (en) 2015-04-27
AU2013320407A1 (en) 2015-04-16
HUE029841T2 (en) 2017-04-28
PL2897970T3 (pl) 2017-08-31
CR20150160A (es) 2015-04-30
FR2995605A1 (fr) 2014-03-21
IL237593A0 (en) 2015-04-30
MA37999A1 (fr) 2016-05-31
DK2897970T3 (en) 2016-11-07
CL2015000659A1 (es) 2015-07-10
ZA201501597B (en) 2016-01-27
US20150210729A1 (en) 2015-07-30
DOP2015000062A (es) 2015-04-15
MX2015003503A (es) 2015-10-26
IL237593A (en) 2017-08-31

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