FI895531A0 - Menetelmä valmistaa farmakologisesti vaikuttavia kinuklidiineja - Google Patents

Menetelmä valmistaa farmakologisesti vaikuttavia kinuklidiineja

Info

Publication number
FI895531A0
FI895531A0 FI895531A FI895531A FI895531A0 FI 895531 A0 FI895531 A0 FI 895531A0 FI 895531 A FI895531 A FI 895531A FI 895531 A FI895531 A FI 895531A FI 895531 A0 FI895531 A0 FI 895531A0
Authority
FI
Finland
Prior art keywords
quinuclidines
pharmacologically active
method produces
produces pharmacologically
active
Prior art date
Application number
FI895531A
Other languages
English (en)
Swedish (sv)
Other versions
FI91637C (fi
FI91637B (fi
Inventor
Gerhard Walther
Karl-Heinz Weber
Werner Stransky
Franz Josef Kuhn
Enzio Mueller
Helmut Ensinger
Original Assignee
Boehringer Ingelheim Kg
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Ingelheim Kg filed Critical Boehringer Ingelheim Kg
Publication of FI895531A0 publication Critical patent/FI895531A0/fi
Application granted granted Critical
Publication of FI91637B publication Critical patent/FI91637B/fi
Publication of FI91637C publication Critical patent/FI91637C/fi

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D453/00—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids
    • C07D453/02—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids containing not further condensed quinuclidine ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Neurology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurosurgery (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biomedical Technology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Ophthalmology & Optometry (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
FI895531A 1988-11-22 1989-11-21 Menetelmä valmistaa farmakologisesti vaikuttavia kinuklidiineja FI91637C (fi)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE3839385A DE3839385A1 (de) 1988-11-22 1988-11-22 Neue quinuclidine, ihre herstellung als arzneimittel und verfahren zu ihrer herstellung
DE3839385 1988-11-22

Publications (3)

Publication Number Publication Date
FI895531A0 true FI895531A0 (fi) 1989-11-21
FI91637B FI91637B (fi) 1994-04-15
FI91637C FI91637C (fi) 1994-07-25

Family

ID=6367625

Family Applications (1)

Application Number Title Priority Date Filing Date
FI895531A FI91637C (fi) 1988-11-22 1989-11-21 Menetelmä valmistaa farmakologisesti vaikuttavia kinuklidiineja

Country Status (18)

Country Link
US (2) US5451587A (fi)
EP (1) EP0370415B1 (fi)
JP (1) JPH0686449B2 (fi)
KR (1) KR0165667B1 (fi)
AU (1) AU628884B2 (fi)
BG (1) BG61859B2 (fi)
CA (1) CA2003422C (fi)
DE (3) DE8817121U1 (fi)
DK (1) DK170167B1 (fi)
ES (1) ES2054988T3 (fi)
FI (1) FI91637C (fi)
HU (1) HU202527B (fi)
IE (1) IE62328B1 (fi)
IL (1) IL92377A (fi)
NO (1) NO172801C (fi)
NZ (1) NZ231445A (fi)
PT (1) PT92368B (fi)
ZA (1) ZA898858B (fi)

Families Citing this family (40)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1307790C (en) * 1987-08-04 1992-09-22 Ian Anthony Cliffe Ethers
YU84791A (sh) * 1990-05-19 1994-06-10 Boehringer Ingelheim Kg. Biciklicni 1-aza-cikloalkalni
EP0492903A1 (en) * 1990-12-21 1992-07-01 MERCK SHARP & DOHME LTD. Substituted pyrazines, pyrimidines and pyridazines for use in the treatment of glaucoma
EP0492902A1 (en) * 1990-12-21 1992-07-01 MERCK SHARP & DOHME LTD. Substituted pyridine derivatives for use in the treatment of glaucoma
EP0492904A1 (en) * 1990-12-21 1992-07-01 MERCK SHARP & DOHME LTD. Substituted benzene derivatives for use in the treatment of glaucoma
ZA92278B (en) * 1991-02-01 1992-10-28 Akzo Nv 3-quinuclidine derivatives
GB9122988D0 (en) * 1991-10-30 1991-12-18 Ici Plc Heterocyclic compounds
GB9127279D0 (en) * 1991-12-23 1992-02-19 Ici Plc Heterocyclic derivatives
JPH06508377A (ja) * 1992-04-10 1994-09-22 ゼネカ　リミテッド ヘテロ環式化合物
GB9211796D0 (en) * 1992-06-04 1992-07-15 Ici Plc Heterocyclic derivatives
GB9216721D0 (en) * 1992-08-06 1992-09-23 Ici Plc Therapeutic heterocyclic derivatives
GB9218334D0 (en) * 1992-08-28 1992-10-14 Ici Plc Heterocyclic compounds
DE4236331A1 (de) * 1992-10-28 1994-05-05 Boehringer Ingelheim Kg Synergistische Kombination
GB9226573D0 (en) * 1992-12-21 1993-02-17 Ici Plc Heterocyclic compounds
US5998404A (en) 1994-10-24 1999-12-07 Eli Lilly And Company Heterocyclic compounds and their use
US5512574A (en) * 1994-12-21 1996-04-30 American Home Products Corporation Quinuclidine and azabicyclo 2.2.1! heptane pyrazinyl ethers as muscarinic agonists
EP0785198B1 (de) 1996-01-19 2000-07-05 Lonza Ag Verfahren zur Herstellung von optisch aktivem 3-Chinuclidinol
SE9600683D0 (sv) * 1996-02-23 1996-02-23 Astra Ab Azabicyclic esters of carbamic acids useful in therapy
CZ54498A3 (cs) * 1997-03-07 1998-11-11 Lonza Ag Katalyzátorová směs na bázi amorfního částečně dehydratovaného hydroxidu zirkoničitého a způsob její výroby a použití
WO1998046225A1 (en) * 1997-04-11 1998-10-22 Eli Lilly And Company Method for treating schizophrenia
US6528529B1 (en) 1998-03-31 2003-03-04 Acadia Pharmaceuticals Inc. Compounds with activity on muscarinic receptors
DE10106971A1 (de) * 2001-02-15 2002-08-29 Boehringer Ingelheim Pharma Arzneimittelformulierung die einen muskarinischen Agonisten enthält
KR100448002B1 (ko) * 2002-02-01 2004-09-13 한국과학기술연구원 신규한 퀴누클리딘 화합물 및 그 제조방법
KR20030083289A (ko) * 2002-04-20 2003-10-30 한승호 다공질 화분
GB0220581D0 (en) 2002-09-04 2002-10-09 Novartis Ag Organic Compound
PE20060437A1 (es) 2004-06-18 2006-06-08 Novartis Ag COMPUESTOS AZA-BICICLONONANOS COMO LIGANDOS COLINERGICOS DE nAChR
GB0415746D0 (en) 2004-07-14 2004-08-18 Novartis Ag Organic compounds
CA2620333A1 (en) * 2005-08-26 2007-03-01 Braincells, Inc. Neurogenesis by muscarinic receptor modulation
EP2258359A3 (en) 2005-08-26 2011-04-06 Braincells, Inc. Neurogenesis by muscarinic receptor modulation with sabcomelin
GB0521508D0 (en) 2005-10-21 2005-11-30 Novartis Ag Organic compounds
EP2377530A3 (en) 2005-10-21 2012-06-20 Braincells, Inc. Modulation of neurogenesis by PDE inhibition
WO2007053596A1 (en) 2005-10-31 2007-05-10 Braincells, Inc. Gaba receptor mediated modulation of neurogenesis
GB0525672D0 (en) 2005-12-16 2006-01-25 Novartis Ag Organic compounds
GB0525673D0 (en) 2005-12-16 2006-01-25 Novartis Ag Organic compounds
US20100216734A1 (en) 2006-03-08 2010-08-26 Braincells, Inc. Modulation of neurogenesis by nootropic agents
EP2026813A2 (en) 2006-05-09 2009-02-25 Braincells, Inc. 5 ht receptor mediated neurogenesis
JP2009536669A (ja) 2006-05-09 2009-10-15 ブレインセルス，インコーポレイティド アンジオテンシン調節による神経新生
KR20090064418A (ko) 2006-09-08 2009-06-18 브레인셀즈 인코퍼레이션 4-아실아미노피리딘 유도체 포함 조합물
US20100184806A1 (en) 2006-09-19 2010-07-22 Braincells, Inc. Modulation of neurogenesis by ppar agents
US20100216805A1 (en) 2009-02-25 2010-08-26 Braincells, Inc. Modulation of neurogenesis using d-cycloserine combinations

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2014831A1 (en) * 1968-08-01 1970-04-24 Sogeras Quinuclidinyl and quinuclidinylalkyl ethers with cholino - lytic, antihistaminic and neurosedative activity
IE63906B1 (en) * 1987-11-13 1995-06-14 Novo Nordisk As Azabicyclic compounds and their preparation and use

Also Published As

Publication number Publication date
DE58904567D1 (de) 1993-07-08
DE8817121U1 (fi) 1993-02-04
DK584089D0 (da) 1989-11-21
PT92368A (pt) 1990-05-31
NO894630D0 (no) 1989-11-21
US5451587A (en) 1995-09-19
JPH02243688A (ja) 1990-09-27
PT92368B (pt) 1995-07-18
CA2003422C (en) 1999-12-21
EP0370415A1 (de) 1990-05-30
FI91637C (fi) 1994-07-25
HUT53102A (en) 1990-09-28
US5508405A (en) 1996-04-16
IL92377A0 (en) 1990-07-26
NO172801C (no) 1993-09-08
DE3839385A1 (de) 1990-05-23
IE893712L (en) 1990-05-22
DK584089A (da) 1990-05-23
IE62328B1 (en) 1995-01-25
BG61859B2 (bg) 1998-07-31
KR900007837A (ko) 1990-06-02
HU202527B (en) 1991-03-28
IL92377A (en) 1995-01-24
FI91637B (fi) 1994-04-15
JPH0686449B2 (ja) 1994-11-02
NO894630L (no) 1990-05-23
NO172801B (no) 1993-06-01
KR0165667B1 (ko) 1999-01-15
HU896032D0 (en) 1990-02-28
DK170167B1 (da) 1995-06-06
EP0370415B1 (de) 1993-06-02
AU628884B2 (en) 1992-09-24
ZA898858B (en) 1991-07-31
AU4540389A (en) 1990-05-31
NZ231445A (en) 1991-08-27
ES2054988T3 (es) 1994-08-16
CA2003422A1 (en) 1990-05-22

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Legal Events

Date Code Title Description
FG Patent granted

Owner name: BOEHRINGER INGELHEIM KG

BB Publication of examined application
FG Patent granted

Owner name: BOEHRINGER INGELHEIM KG