NO894630D0 - Fremgangsmaate for fremstilling av terapeutisk aktive kinuklidin-derivater. - Google Patents

Fremgangsmaate for fremstilling av terapeutisk aktive kinuklidin-derivater.

Info

Publication number
NO894630D0
NO894630D0 NO894630A NO894630A NO894630D0 NO 894630 D0 NO894630 D0 NO 894630D0 NO 894630 A NO894630 A NO 894630A NO 894630 A NO894630 A NO 894630A NO 894630 D0 NO894630 D0 NO 894630D0
Authority
NO
Norway
Prior art keywords
kinuclidine
derivatives
procedure
preparation
therapeutic active
Prior art date
Application number
NO894630A
Other languages
English (en)
Other versions
NO172801C (no
NO172801B (no
NO894630L (no
Inventor
Gerhard Walther
Karl-Heinz Weber
Werner Stransky
Franz Josef Kuhn
Enzio Mueller
Helmut Ensinger
Original Assignee
Boehringer Ingelheim Kg
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Ingelheim Kg filed Critical Boehringer Ingelheim Kg
Publication of NO894630D0 publication Critical patent/NO894630D0/no
Publication of NO894630L publication Critical patent/NO894630L/no
Publication of NO172801B publication Critical patent/NO172801B/no
Publication of NO172801C publication Critical patent/NO172801C/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D453/00—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids
    • C07D453/02—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids containing not further condensed quinuclidine ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Veterinary Medicine (AREA)
  • Biomedical Technology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Ophthalmology & Optometry (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
NO894630A 1988-11-22 1989-11-21 Analogifremgangsmaate for fremstilling av terapeutisk aktive kinuklidin-derivater NO172801C (no)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE3839385A DE3839385A1 (de) 1988-11-22 1988-11-22 Neue quinuclidine, ihre herstellung als arzneimittel und verfahren zu ihrer herstellung

Publications (4)

Publication Number Publication Date
NO894630D0 true NO894630D0 (no) 1989-11-21
NO894630L NO894630L (no) 1990-05-23
NO172801B NO172801B (no) 1993-06-01
NO172801C NO172801C (no) 1993-09-08

Family

ID=6367625

Family Applications (1)

Application Number Title Priority Date Filing Date
NO894630A NO172801C (no) 1988-11-22 1989-11-21 Analogifremgangsmaate for fremstilling av terapeutisk aktive kinuklidin-derivater

Country Status (18)

Country Link
US (2) US5451587A (no)
EP (1) EP0370415B1 (no)
JP (1) JPH0686449B2 (no)
KR (1) KR0165667B1 (no)
AU (1) AU628884B2 (no)
BG (1) BG61859B2 (no)
CA (1) CA2003422C (no)
DE (3) DE3839385A1 (no)
DK (1) DK170167B1 (no)
ES (1) ES2054988T3 (no)
FI (1) FI91637C (no)
HU (1) HU202527B (no)
IE (1) IE62328B1 (no)
IL (1) IL92377A (no)
NO (1) NO172801C (no)
NZ (1) NZ231445A (no)
PT (1) PT92368B (no)
ZA (1) ZA898858B (no)

Families Citing this family (41)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1307790C (en) * 1987-08-04 1992-09-22 Ian Anthony Cliffe Ethers
YU84791A (sh) * 1990-05-19 1994-06-10 Boehringer Ingelheim Kg. Biciklicni 1-aza-cikloalkalni
EP0492902A1 (en) * 1990-12-21 1992-07-01 MERCK SHARP & DOHME LTD. Substituted pyridine derivatives for use in the treatment of glaucoma
EP0492904A1 (en) * 1990-12-21 1992-07-01 MERCK SHARP & DOHME LTD. Substituted benzene derivatives for use in the treatment of glaucoma
EP0492903A1 (en) * 1990-12-21 1992-07-01 MERCK SHARP & DOHME LTD. Substituted pyrazines, pyrimidines and pyridazines for use in the treatment of glaucoma
ZA92278B (en) * 1991-02-01 1992-10-28 Akzo Nv 3-quinuclidine derivatives
GB9122988D0 (en) * 1991-10-30 1991-12-18 Ici Plc Heterocyclic compounds
GB9127279D0 (en) * 1991-12-23 1992-02-19 Ici Plc Heterocyclic derivatives
WO1993021184A1 (en) * 1992-04-10 1993-10-28 Zeneca Limited Biphenylylquinuclidine derivatives as squalene synthase inhibitors
GB9211796D0 (en) * 1992-06-04 1992-07-15 Ici Plc Heterocyclic derivatives
GB9216721D0 (en) * 1992-08-06 1992-09-23 Ici Plc Therapeutic heterocyclic derivatives
GB9218334D0 (en) * 1992-08-28 1992-10-14 Ici Plc Heterocyclic compounds
DE4236331A1 (de) * 1992-10-28 1994-05-05 Boehringer Ingelheim Kg Synergistische Kombination
GB9226573D0 (en) * 1992-12-21 1993-02-17 Ici Plc Heterocyclic compounds
US5998404A (en) * 1994-10-24 1999-12-07 Eli Lilly And Company Heterocyclic compounds and their use
US5512574A (en) * 1994-12-21 1996-04-30 American Home Products Corporation Quinuclidine and azabicyclo 2.2.1! heptane pyrazinyl ethers as muscarinic agonists
EP0785198B1 (de) 1996-01-19 2000-07-05 Lonza Ag Verfahren zur Herstellung von optisch aktivem 3-Chinuclidinol
SE9600683D0 (sv) * 1996-02-23 1996-02-23 Astra Ab Azabicyclic esters of carbamic acids useful in therapy
CZ54498A3 (cs) * 1997-03-07 1998-11-11 Lonza Ag Katalyzátorová směs na bázi amorfního částečně dehydratovaného hydroxidu zirkoničitého a způsob její výroby a použití
AU6896098A (en) * 1997-04-11 1998-11-11 Eli Lilly And Company Method for treating schizophrenia
US6528529B1 (en) 1998-03-31 2003-03-04 Acadia Pharmaceuticals Inc. Compounds with activity on muscarinic receptors
DE10106971A1 (de) * 2001-02-15 2002-08-29 Boehringer Ingelheim Pharma Arzneimittelformulierung die einen muskarinischen Agonisten enthält
KR100448002B1 (ko) * 2002-02-01 2004-09-13 한국과학기술연구원 신규한 퀴누클리딘 화합물 및 그 제조방법
KR20030083289A (ko) * 2002-04-20 2003-10-30 한승호 다공질 화분
GB0220581D0 (en) 2002-09-04 2002-10-09 Novartis Ag Organic Compound
AR049401A1 (es) 2004-06-18 2006-07-26 Novartis Ag Aza-biciclononanos
GB0415746D0 (en) 2004-07-14 2004-08-18 Novartis Ag Organic compounds
JP2009506069A (ja) 2005-08-26 2009-02-12 ブレインセルス，インコーポレイティド ムスカリン性受容体調節による神経発生
EP2258359A3 (en) 2005-08-26 2011-04-06 Braincells, Inc. Neurogenesis by muscarinic receptor modulation with sabcomelin
GB0521508D0 (en) 2005-10-21 2005-11-30 Novartis Ag Organic compounds
AU2006304787A1 (en) 2005-10-21 2007-04-26 Braincells, Inc. Modulation of neurogenesis by PDE inhibition
CA2625210A1 (en) 2005-10-31 2007-05-10 Braincells, Inc. Gaba receptor mediated modulation of neurogenesis
GB0525673D0 (en) 2005-12-16 2006-01-25 Novartis Ag Organic compounds
GB0525672D0 (en) 2005-12-16 2006-01-25 Novartis Ag Organic compounds
US20100216734A1 (en) 2006-03-08 2010-08-26 Braincells, Inc. Modulation of neurogenesis by nootropic agents
US7678808B2 (en) 2006-05-09 2010-03-16 Braincells, Inc. 5 HT receptor mediated neurogenesis
AU2007249399A1 (en) 2006-05-09 2007-11-22 Braincells, Inc. Neurogenesis by modulating angiotensin
EP2068872A1 (en) 2006-09-08 2009-06-17 Braincells, Inc. Combinations containing a 4-acylaminopyridine derivative
US20100184806A1 (en) 2006-09-19 2010-07-22 Braincells, Inc. Modulation of neurogenesis by ppar agents
WO2010099217A1 (en) 2009-02-25 2010-09-02 Braincells, Inc. Modulation of neurogenesis using d-cycloserine combinations
JP2022511051A (ja) * 2018-12-05 2022-01-28 レンズ・セラピューティクス・インコーポレイテッド キヌクリジン環含有ムスカリン性アゴニストのプロドラッグ及びその組成物ならびに方法

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2014831A1 (en) * 1968-08-01 1970-04-24 Sogeras Quinuclidinyl and quinuclidinylalkyl ethers with cholino - lytic, antihistaminic and neurosedative activity
IE63906B1 (en) * 1987-11-13 1995-06-14 Novo Nordisk As Azabicyclic compounds and their preparation and use

Also Published As

Publication number Publication date
IE893712L (en) 1990-05-22
AU628884B2 (en) 1992-09-24
CA2003422C (en) 1999-12-21
HUT53102A (en) 1990-09-28
HU202527B (en) 1991-03-28
EP0370415B1 (de) 1993-06-02
IL92377A (en) 1995-01-24
NO172801C (no) 1993-09-08
NO172801B (no) 1993-06-01
FI91637B (fi) 1994-04-15
JPH0686449B2 (ja) 1994-11-02
DE3839385A1 (de) 1990-05-23
KR900007837A (ko) 1990-06-02
HU896032D0 (en) 1990-02-28
DE8817121U1 (de) 1993-02-04
PT92368A (pt) 1990-05-31
FI91637C (fi) 1994-07-25
BG61859B2 (bg) 1998-07-31
DE58904567D1 (de) 1993-07-08
KR0165667B1 (ko) 1999-01-15
NZ231445A (en) 1991-08-27
PT92368B (pt) 1995-07-18
US5451587A (en) 1995-09-19
DK584089D0 (da) 1989-11-21
JPH02243688A (ja) 1990-09-27
NO894630L (no) 1990-05-23
ES2054988T3 (es) 1994-08-16
IE62328B1 (en) 1995-01-25
DK170167B1 (da) 1995-06-06
US5508405A (en) 1996-04-16
AU4540389A (en) 1990-05-31
ZA898858B (en) 1991-07-31
EP0370415A1 (de) 1990-05-30
IL92377A0 (en) 1990-07-26
DK584089A (da) 1990-05-23
CA2003422A1 (en) 1990-05-22
FI895531A0 (fi) 1989-11-21

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