FI71300C - Foerfarande foer framstaellning av salter och estrar av syran som svarar mot monakolin-k vilka har antihyperkolesteremisk effekt - Google Patents

Foerfarande foer framstaellning av salter och estrar av syran som svarar mot monakolin-k vilka har antihyperkolesteremisk effekt Download PDF

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Publication number
FI71300C
FI71300C FI802357A FI802357A FI71300C FI 71300 C FI71300 C FI 71300C FI 802357 A FI802357 A FI 802357A FI 802357 A FI802357 A FI 802357A FI 71300 C FI71300 C FI 71300C
Authority
FI
Finland
Prior art keywords
monacoline
solution
monacolin
salt
esters
Prior art date
Application number
FI802357A
Other languages
English (en)
Finnish (fi)
Other versions
FI802357A (fi
FI71300B (fi
Inventor
Yoshio Tsujita
Kazuhiko Tanzawa
Masao Kuroda
Seigo Iwado
Kiyoshi Hamano
Akira Terahara
Sadao Sato
Original Assignee
Sankyo Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from JP9581479A external-priority patent/JPS5621594A/ja
Priority claimed from JP12346179A external-priority patent/JPS5646841A/ja
Application filed by Sankyo Co filed Critical Sankyo Co
Publication of FI802357A publication Critical patent/FI802357A/fi
Application granted granted Critical
Publication of FI71300B publication Critical patent/FI71300B/fi
Publication of FI71300C publication Critical patent/FI71300C/fi

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C59/40—Unsaturated compounds
    • C07C59/42—Unsaturated compounds containing hydroxy or O-metal groups
    • C07C59/46—Unsaturated compounds containing hydroxy or O-metal groups containing rings other than six-membered aromatic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
    • C07C69/66—Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety
    • C07C69/73—Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety of unsaturated acids
    • C07C69/732—Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety of unsaturated acids of unsaturated hydroxy carboxylic acids
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02E—REDUCTION OF GREENHOUSE GAS [GHG] EMISSIONS, RELATED TO ENERGY GENERATION, TRANSMISSION OR DISTRIBUTION
    • Y02E50/00—Technologies for the production of fuel of non-fossil origin
    • Y02E50/10—Biofuels, e.g. bio-diesel

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
FI802357A 1979-07-27 1980-07-25 Foerfarande foer framstaellning av salter och estrar av syran som svarar mot monakolin-k vilka har antihyperkolesteremisk effekt FI71300C (fi)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
JP9581479 1979-07-27
JP9581479A JPS5621594A (en) 1979-07-27 1979-07-27 Mb-530b carboxylic acid metal salt and its preparation
JP12346179A JPS5646841A (en) 1979-09-26 1979-09-26 Mb-530b carboxylic acid ester and its preparation
JP12346179 1979-09-26

Publications (3)

Publication Number Publication Date
FI802357A FI802357A (fi) 1981-01-28
FI71300B FI71300B (fi) 1986-09-09
FI71300C true FI71300C (fi) 1986-12-19

Family

ID=26436995

Family Applications (1)

Application Number Title Priority Date Filing Date
FI802357A FI71300C (fi) 1979-07-27 1980-07-25 Foerfarande foer framstaellning av salter och estrar av syran som svarar mot monakolin-k vilka har antihyperkolesteremisk effekt

Country Status (16)

Country Link
AT (1) AT375334B (fr)
AU (1) AU6083980A (fr)
CH (1) CH647749A5 (fr)
DD (1) DD153827A5 (fr)
DE (1) DE3028284A1 (fr)
DK (1) DK322380A (fr)
ES (1) ES493726A0 (fr)
FI (1) FI71300C (fr)
FR (1) FR2462417A1 (fr)
GB (1) GB2055100A (fr)
IT (1) IT1147763B (fr)
NL (1) NL8004303A (fr)
NO (1) NO156210C (fr)
NZ (1) NZ194445A (fr)
PL (1) PL225901A1 (fr)
SE (1) SE445828B (fr)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1327360C (fr) * 1983-11-14 1994-03-01 William F. Hoffman Analogues oxo d'agents antihypercholesterolemiants ayant les caracteristiques de la mevinoline
DE3580863D1 (de) * 1984-06-04 1991-01-24 Merck & Co Inc Herstellungsverfahren von hemmstoffen der hmg-coa-reduktase mit einer 3,5-dihydroxypentanoatteilstruktur.
EP0204287A3 (fr) * 1985-06-04 1987-07-01 Merck & Co. Inc. Procédé de préparation d'inhibiteurs de la HMG-CoA réductase ayant des sous-groupes 3,5-dihydroxy pentanoiques
US4611081A (en) * 1985-07-05 1986-09-09 Merck & Co., Inc. Process for the preparation of HMG-CoA reductase inhibitors intermediates
USRE33033E (en) * 1985-07-05 1989-08-22 Merck & Co., Inc. Process for the preparation of HMG-CoA reductase inhibitors intermediates
US7238348B2 (en) 1996-09-30 2007-07-03 Beijing Peking University Wbl Corporation Ltd. Method of treatment of osteoporosis with compositions of red rice fermentation products
US6046022A (en) 1996-09-30 2000-04-04 Peking University Methods and compositions employing red rice fermentation products
JP2002518448A (ja) * 1998-06-24 2002-06-25 メルク エンド カムパニー インコーポレーテッド 高血中コレステロールを治療する組成物および方法
SI20070A (sl) 1998-09-18 2000-04-30 LEK, tovarna farmacevtskih in kemi�nih izdelkov, d.d. Nove soli inhibitorjev HMG-CoA reduktaze
US6806290B2 (en) 2000-06-09 2004-10-19 Lek Pharmaceuticals D.D. Stabilized pharmaceutically effective composition and pharmaceutical formulation comprising the same
SI1292293T1 (en) * 2000-06-09 2004-06-30 LEK farmacevtska dru�ba d.d. Stabilized pharmaceutically effective composition and pharmaceutical formulation comprising the same
CA2421018A1 (fr) * 2000-09-06 2002-03-14 Merck & Co., Inc. Sel d'acide ouvert dihydroxy de simvastatine
EA200400034A1 (ru) 2001-06-13 2004-06-24 Ранбакси Лабораторис Лимитед МЕТИЛОВЫЕ АНАЛОГИ СИМВАСТАТИНА В КАЧЕСТВЕ НОВЫХ ИНГИБИТОРОВ HMG-CoA РЕДУКТАЗЫ
KR100379075B1 (en) 2002-03-07 2003-04-08 Jinis Biopharmaceuticals Co Method for producing low cholesterol animal food product and food product therefrom
US8158362B2 (en) 2005-03-30 2012-04-17 Decode Genetics Ehf. Methods of diagnosing susceptibility to myocardial infarction and screening for an LTA4H haplotype
CN101659923B (zh) * 2008-08-26 2011-10-26 北京北大维信生物科技有限公司 一种制备开环式洛伐他汀的方法

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2748825C2 (de) * 1976-11-02 1986-11-27 Sankyo Co., Ltd., Tokio/Tokyo Substituierte 3,5-Dihydroxyheptansäurederivate und diese enthaltende Arzneimittel gegen Hyperlipämie
JPS55150898A (en) * 1979-05-11 1980-11-25 Sankyo Co Ltd Preparation of a new physiologically active substance mb-530b

Also Published As

Publication number Publication date
SE445828B (sv) 1986-07-21
NL8004303A (nl) 1981-01-29
IT8068211A0 (it) 1980-07-28
ATA392380A (de) 1983-12-15
SE8005386L (sv) 1981-01-28
DD153827A5 (de) 1982-02-03
DK322380A (da) 1981-01-28
ES8105781A1 (es) 1981-06-16
FR2462417A1 (fr) 1981-02-13
NO802244L (no) 1981-01-28
NO156210B (no) 1987-05-04
DE3028284C2 (fr) 1990-08-09
FR2462417B1 (fr) 1984-01-20
AT375334B (de) 1984-07-25
FI802357A (fi) 1981-01-28
NZ194445A (en) 1984-07-06
ES493726A0 (es) 1981-06-16
CH647749A5 (de) 1985-02-15
DE3028284A1 (de) 1981-02-19
NO156210C (no) 1987-08-12
IT1147763B (it) 1986-11-26
AU6083980A (en) 1981-01-29
GB2055100A (en) 1981-02-25
FI71300B (fi) 1986-09-09
PL225901A1 (fr) 1982-07-19

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Owner name: SANKYO COMPANY LIMITED