JPS5646841A - Mb-530b carboxylic acid ester and its preparation - Google Patents
Mb-530b carboxylic acid ester and its preparationInfo
- Publication number
- JPS5646841A JPS5646841A JP12346179A JP12346179A JPS5646841A JP S5646841 A JPS5646841 A JP S5646841A JP 12346179 A JP12346179 A JP 12346179A JP 12346179 A JP12346179 A JP 12346179A JP S5646841 A JPS5646841 A JP S5646841A
- Authority
- JP
- Japan
- Prior art keywords
- carboxylic acid
- alkyl
- acid ester
- preparation
- alkoxy
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Landscapes
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
NEW MATERIAL:An MB-530B carboxylic acid ester of formula (R is alkyl, benzyl which may be substituted with alkyl, alkoxy or halogen, or phenacyl which may be substituted with alkyl, alkoxy or halogen).
EXAMPLE: MB-530B carboxylic acid methyl ester.
USE: It is effective to inhibit the synthesis of cholesterol and depress the lipid level in blood, and is useful, e.g. as an antilipemic agent, anti-arteriosclerotic agent, etc. It is preferably administered orally.
PROCESS: The compound of the formula is prepared by reacting an alcohol with MB-530B obtained by culturing MB-530B-producing bacteria belonging to Monascus genus, e.g. Monascus anca SANK 10171 (IFO 6540), etc.
COPYRIGHT: (C)1981,JPO&Japio
Priority Applications (18)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP12346179A JPS5646841A (en) | 1979-09-26 | 1979-09-26 | Mb-530b carboxylic acid ester and its preparation |
ES493726A ES493726A0 (en) | 1979-07-27 | 1980-07-24 | A PROCEDURE FOR THE PREPARATION OF SALTS AND ESTERS OF MONACOLINE K USEFUL AS ANTITLIPERCOLESTEREMIC AGENTS. |
DK322380A DK322380A (en) | 1979-07-27 | 1980-07-25 | PROCEDURE FOR THE PREPARATION OF MONACOLIN K SALTS OR ESTERS |
FI802357A FI71300C (en) | 1979-07-27 | 1980-07-25 | FOERFARANDE FOER FRAMSTAELLNING AV SALTER OCH ESTRAR AV SYRAN SOM SVARAR MOT MONACOLIN-K VILKA HAR ANTIHYPERKOLESTEREMISK EFFEKT |
DE19803028284 DE3028284A1 (en) | 1979-07-27 | 1980-07-25 | MONACOLIN K DERIVATIVES, METHOD FOR THE PRODUCTION THEREOF AND MEDICINAL PRODUCTS CONTAINING THESE DERIVATIVES |
FR8016452A FR2462417A1 (en) | 1979-07-27 | 1980-07-25 | NOVEL MONACOLIN K DERIVATIVES, THEIR PREPARATION PROCESS AND THEIR THERAPEUTIC APPLICATION |
DE19803051206 DE3051206C2 (en) | 1979-07-27 | 1980-07-25 | Hypocholesterolaemic salts and ester(s) from monacolin K - are prepd. by cultivation of monascus strains followed by salification or esterification |
NO802244A NO156210C (en) | 1979-07-27 | 1980-07-25 | PROCEDURE FOR THE PREPARATION OF MONACOLIN K DERIVATIVES. |
NZ194445A NZ194445A (en) | 1979-07-27 | 1980-07-25 | Monacolin k salts and esters |
SE8005386A SE445828B (en) | 1979-07-27 | 1980-07-25 | SALTS AND ESTERS OF MONACOLINE K FOR USE AS ANTI-HYPERCOLESTEROLEMIC AGENTS |
CH5736/80A CH647749A5 (en) | 1979-07-27 | 1980-07-25 | MONACOLIN-K SALTS AND ESTERS, PRODUCTION METHOD AND PHARMACEUTICAL PREPARATIONS. |
PL22590180A PL225901A1 (en) | 1979-07-27 | 1980-07-26 | |
NL8004303A NL8004303A (en) | 1979-07-27 | 1980-07-27 | MONACOLINE K CONNECTIONS. |
GB8024665A GB2055100A (en) | 1979-07-27 | 1980-07-28 | Monacolin K derivatives |
AT0392380A AT375334B (en) | 1979-07-27 | 1980-07-28 | METHOD FOR PRODUCING NEW SALTS OR ESTERS |
AU60839/80A AU6083980A (en) | 1979-07-27 | 1980-07-28 | Monacolin k derivatives |
IT68211/80A IT1147763B (en) | 1979-07-27 | 1980-07-28 | COMPOUNDS THAT CAN BE USED AS CHOLESTEROL BIOSYNTHESIS INHIBITORS AND PROCEDURE FOR THEIR PREPARATION |
DD80222916A DD153827A5 (en) | 1979-07-27 | 1980-07-28 | PROCESS FOR PREPARING ANTIHYPERCHOLESTERINA MIXTURES |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP12346179A JPS5646841A (en) | 1979-09-26 | 1979-09-26 | Mb-530b carboxylic acid ester and its preparation |
Publications (2)
Publication Number | Publication Date |
---|---|
JPS5646841A true JPS5646841A (en) | 1981-04-28 |
JPS6320215B2 JPS6320215B2 (en) | 1988-04-26 |
Family
ID=14861197
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP12346179A Granted JPS5646841A (en) | 1979-07-27 | 1979-09-26 | Mb-530b carboxylic acid ester and its preparation |
Country Status (1)
Country | Link |
---|---|
JP (1) | JPS5646841A (en) |
-
1979
- 1979-09-26 JP JP12346179A patent/JPS5646841A/en active Granted
Also Published As
Publication number | Publication date |
---|---|
JPS6320215B2 (en) | 1988-04-26 |
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