JPS5566577A - Novel carboxylic derivative and its preparation - Google Patents
Novel carboxylic derivative and its preparationInfo
- Publication number
- JPS5566577A JPS5566577A JP13892878A JP13892878A JPS5566577A JP S5566577 A JPS5566577 A JP S5566577A JP 13892878 A JP13892878 A JP 13892878A JP 13892878 A JP13892878 A JP 13892878A JP S5566577 A JPS5566577 A JP S5566577A
- Authority
- JP
- Japan
- Prior art keywords
- preparation
- formula
- orally
- compound
- carboxylic derivative
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Landscapes
- Heterocyclic Compounds Containing Sulfur Atoms (AREA)
- Pyrane Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
NEW MATERIAL:Carboxylic derivatives of formula I (A is O, S; R1 is H, methyl; R2 is hydroxyl, amino) and their nontoxic salts.
EXAMPLE: 2-[10,11-Dihydro-11-hydroxybenz(b,f)apin-2-yl]propioic acid.
USE: They have anti-inflammatory activity and are used as anti-inflammatory. They may orally or non-orally be administered.
PREPARATION: The reduction of a compound of formula II is effected in an organic solvent as alcohol or ether using a reducing reagent as sodium borohydride to give the compound of formula I. The nontoxic salt is, e.g., a metal salt of sodium or calcium or amine salt.
COPYRIGHT: (C)1980,JPO&Japio
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP13892878A JPS5566577A (en) | 1978-11-13 | 1978-11-13 | Novel carboxylic derivative and its preparation |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP13892878A JPS5566577A (en) | 1978-11-13 | 1978-11-13 | Novel carboxylic derivative and its preparation |
Publications (2)
Publication Number | Publication Date |
---|---|
JPS5566577A true JPS5566577A (en) | 1980-05-20 |
JPS6141359B2 JPS6141359B2 (en) | 1986-09-13 |
Family
ID=15233408
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP13892878A Granted JPS5566577A (en) | 1978-11-13 | 1978-11-13 | Novel carboxylic derivative and its preparation |
Country Status (1)
Country | Link |
---|---|
JP (1) | JPS5566577A (en) |
Families Citing this family (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPH01150479U (en) * | 1988-04-07 | 1989-10-18 |
-
1978
- 1978-11-13 JP JP13892878A patent/JPS5566577A/en active Granted
Also Published As
Publication number | Publication date |
---|---|
JPS6141359B2 (en) | 1986-09-13 |
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