JPS5566577A - Novel carboxylic derivative and its preparation - Google Patents

Novel carboxylic derivative and its preparation

Info

Publication number
JPS5566577A
JPS5566577A JP13892878A JP13892878A JPS5566577A JP S5566577 A JPS5566577 A JP S5566577A JP 13892878 A JP13892878 A JP 13892878A JP 13892878 A JP13892878 A JP 13892878A JP S5566577 A JPS5566577 A JP S5566577A
Authority
JP
Japan
Prior art keywords
preparation
formula
orally
compound
carboxylic derivative
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP13892878A
Other languages
Japanese (ja)
Other versions
JPS6141359B2 (en
Inventor
Yasuo Fujimoto
Shigeru Yamabe
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Nippon Chemiphar Co Ltd
Original Assignee
Nippon Chemiphar Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nippon Chemiphar Co Ltd filed Critical Nippon Chemiphar Co Ltd
Priority to JP13892878A priority Critical patent/JPS5566577A/en
Publication of JPS5566577A publication Critical patent/JPS5566577A/en
Publication of JPS6141359B2 publication Critical patent/JPS6141359B2/ja
Granted legal-status Critical Current

Links

Landscapes

  • Heterocyclic Compounds Containing Sulfur Atoms (AREA)
  • Pyrane Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

NEW MATERIAL:Carboxylic derivatives of formula I (A is O, S; R1 is H, methyl; R2 is hydroxyl, amino) and their nontoxic salts.
EXAMPLE: 2-[10,11-Dihydro-11-hydroxybenz(b,f)apin-2-yl]propioic acid.
USE: They have anti-inflammatory activity and are used as anti-inflammatory. They may orally or non-orally be administered.
PREPARATION: The reduction of a compound of formula II is effected in an organic solvent as alcohol or ether using a reducing reagent as sodium borohydride to give the compound of formula I. The nontoxic salt is, e.g., a metal salt of sodium or calcium or amine salt.
COPYRIGHT: (C)1980,JPO&Japio
JP13892878A 1978-11-13 1978-11-13 Novel carboxylic derivative and its preparation Granted JPS5566577A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP13892878A JPS5566577A (en) 1978-11-13 1978-11-13 Novel carboxylic derivative and its preparation

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP13892878A JPS5566577A (en) 1978-11-13 1978-11-13 Novel carboxylic derivative and its preparation

Publications (2)

Publication Number Publication Date
JPS5566577A true JPS5566577A (en) 1980-05-20
JPS6141359B2 JPS6141359B2 (en) 1986-09-13

Family

ID=15233408

Family Applications (1)

Application Number Title Priority Date Filing Date
JP13892878A Granted JPS5566577A (en) 1978-11-13 1978-11-13 Novel carboxylic derivative and its preparation

Country Status (1)

Country Link
JP (1) JPS5566577A (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH01150479U (en) * 1988-04-07 1989-10-18

Also Published As

Publication number Publication date
JPS6141359B2 (en) 1986-09-13

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