JPS57212137A - Preparation of phenyl aliphtic acid derivative - Google Patents
Preparation of phenyl aliphtic acid derivativeInfo
- Publication number
- JPS57212137A JPS57212137A JP9707181A JP9707181A JPS57212137A JP S57212137 A JPS57212137 A JP S57212137A JP 9707181 A JP9707181 A JP 9707181A JP 9707181 A JP9707181 A JP 9707181A JP S57212137 A JPS57212137 A JP S57212137A
- Authority
- JP
- Japan
- Prior art keywords
- acid derivative
- phenyl
- lower alkyl
- aliphtic
- preparation
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Landscapes
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
NEW MATERIAL:A phenyl aliphatic acid derivative shown by the formulaI(R1 is H, halogen, hydroxy, lower alkyl, or lower alkoxy, Ra 2 is H or lower alkyl; R4 is bond valence or lower alkylene; X is O, S, SO, or SO2) or its salt.
EXAMPLE: 3-Methyl-7-(2-fluorophenylthio)-2,3-dihydrobenzofuran-2-one.
USE: Useful as an antiphlogistic, anodyne, and antipyretic, and an intermediate for synthesizing a lactone compound having the same medicinal effects.
PROCESS: A compound shown by the formula II (R2 is H, lower alkyl, or acyl; R3 is lower alkenyl) or its salt is oxidized, and a reaction product wherein the group R2 is acyl is hydrolyzed, to give a compound shown by the formulaI.
COPYRIGHT: (C)1982,JPO&Japio
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP9707181A JPS57212137A (en) | 1981-06-22 | 1981-06-22 | Preparation of phenyl aliphtic acid derivative |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP9707181A JPS57212137A (en) | 1981-06-22 | 1981-06-22 | Preparation of phenyl aliphtic acid derivative |
Publications (1)
Publication Number | Publication Date |
---|---|
JPS57212137A true JPS57212137A (en) | 1982-12-27 |
Family
ID=14182405
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP9707181A Pending JPS57212137A (en) | 1981-06-22 | 1981-06-22 | Preparation of phenyl aliphtic acid derivative |
Country Status (1)
Country | Link |
---|---|
JP (1) | JPS57212137A (en) |
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4906658A (en) * | 1987-04-21 | 1990-03-06 | Merck Frosst Canada, Inc. | Fluoro-sulfones |
ES2163986A1 (en) * | 1999-07-13 | 2002-02-01 | Menarini Lab | Set of inflammation and pain inhibitors for e.g. cyclooxygenase activity inhibitors comprises alpha aryl propionic acids and aryl acetic acids |
-
1981
- 1981-06-22 JP JP9707181A patent/JPS57212137A/en active Pending
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4906658A (en) * | 1987-04-21 | 1990-03-06 | Merck Frosst Canada, Inc. | Fluoro-sulfones |
ES2163986A1 (en) * | 1999-07-13 | 2002-02-01 | Menarini Lab | Set of inflammation and pain inhibitors for e.g. cyclooxygenase activity inhibitors comprises alpha aryl propionic acids and aryl acetic acids |
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