JPS5566576A - Novel carboxylic derivative and its preparation - Google Patents

Novel carboxylic derivative and its preparation

Info

Publication number
JPS5566576A
JPS5566576A JP13892778A JP13892778A JPS5566576A JP S5566576 A JPS5566576 A JP S5566576A JP 13892778 A JP13892778 A JP 13892778A JP 13892778 A JP13892778 A JP 13892778A JP S5566576 A JPS5566576 A JP S5566576A
Authority
JP
Japan
Prior art keywords
formula
compound
preparation
carboxylic derivative
novel carboxylic
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP13892778A
Other languages
Japanese (ja)
Inventor
Yasuo Fujimoto
Shigeru Yamabe
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Nippon Chemiphar Co Ltd
Original Assignee
Nippon Chemiphar Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nippon Chemiphar Co Ltd filed Critical Nippon Chemiphar Co Ltd
Priority to JP13892778A priority Critical patent/JPS5566576A/en
Publication of JPS5566576A publication Critical patent/JPS5566576A/en
Pending legal-status Critical Current

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  • Heterocyclic Compounds Containing Sulfur Atoms (AREA)
  • Pyrane Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

NEW MATERIAL:Carboxylic derivatives of formula I (A is O, S; R1 is H, methyl; R2 is H, lower alkyl).
EXAMPLE: 2-[Dibenz(b,f)apin-2-yl]propioic acid.
USE: They have anti-inflammatory activity and are used as anti-inflammotory. They are both orally and nonorally administered.
PREPARATION: A compound of formula II is heated in the presence of a dehydration agent as phosphoric acid, sulfuric acid, phosphorus pentoxide, or zinc chloride to produce the compound of formula I. The compound of formula II is obtained by reduction of compound of formula III. In another method, a compound of formula IV (R3 is alkyl) is hydrolyzed using an alkali to give the compound of formula I.
COPYRIGHT: (C)1980,JPO&Japio
JP13892778A 1978-11-13 1978-11-13 Novel carboxylic derivative and its preparation Pending JPS5566576A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP13892778A JPS5566576A (en) 1978-11-13 1978-11-13 Novel carboxylic derivative and its preparation

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP13892778A JPS5566576A (en) 1978-11-13 1978-11-13 Novel carboxylic derivative and its preparation

Publications (1)

Publication Number Publication Date
JPS5566576A true JPS5566576A (en) 1980-05-20

Family

ID=15233381

Family Applications (1)

Application Number Title Priority Date Filing Date
JP13892778A Pending JPS5566576A (en) 1978-11-13 1978-11-13 Novel carboxylic derivative and its preparation

Country Status (1)

Country Link
JP (1) JPS5566576A (en)

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