JPS57116035A - Novel benzylideneaminocarboxylic acid derivative and its preparation - Google Patents

Novel benzylideneaminocarboxylic acid derivative and its preparation

Info

Publication number
JPS57116035A
JPS57116035A JP179081A JP179081A JPS57116035A JP S57116035 A JPS57116035 A JP S57116035A JP 179081 A JP179081 A JP 179081A JP 179081 A JP179081 A JP 179081A JP S57116035 A JPS57116035 A JP S57116035A
Authority
JP
Japan
Prior art keywords
compound
benzylideneaminocarboxylic
novel
preparation
acid derivative
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP179081A
Other languages
Japanese (ja)
Inventor
Hitoshi Takita
Mikuo Noda
Yutaka Mukoda
Hidetoshi Kobayashi
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Kureha Corp
Original Assignee
Kureha Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kureha Corp filed Critical Kureha Corp
Priority to JP179081A priority Critical patent/JPS57116035A/en
Priority to US06/267,249 priority patent/US4377594A/en
Priority to AU71168/81A priority patent/AU542972B2/en
Priority to NO811887A priority patent/NO152252C/en
Priority to DE8181302466T priority patent/DE3161771D1/en
Priority to CA000378938A priority patent/CA1183150A/en
Priority to EP81302466A priority patent/EP0041826B1/en
Priority to DK248181A priority patent/DK149769C/en
Publication of JPS57116035A publication Critical patent/JPS57116035A/en
Pending legal-status Critical Current

Links

Abstract

NEW MATERIAL:A compound of formulaI(X1 is hydroxyl or methoxyl; X2 is H or medicinally acceptable metal; m is an integer 2 or 3).
EXAMPLE: N-( 3, 4-Dehydeoxybenzylidene )aminomethyl-cis-cyclohexanecarboxylic acid.
USE: Useful as a remedy for various diseases, e.g. thrombosis or cerebral hemorrhage or an intermediate therefor, and having inhibitory action on blood platelet aggregation, and/or inhibitory action on leukocytotaxia with low toxicity.
PROCESS: A compound of formula II, e.g. hydroxybenzaldehyde, is condensed with a cis-or trans-aminomethylcyclohexancecarboxylic acid of formula III and a salt or an alkyl ester thereof in an organic solvent through dehydration to give the compound of formulaI.
COPYRIGHT: (C)1982,JPO&Japio
JP179081A 1980-06-04 1981-01-09 Novel benzylideneaminocarboxylic acid derivative and its preparation Pending JPS57116035A (en)

Priority Applications (8)

Application Number Priority Date Filing Date Title
JP179081A JPS57116035A (en) 1981-01-09 1981-01-09 Novel benzylideneaminocarboxylic acid derivative and its preparation
US06/267,249 US4377594A (en) 1980-06-04 1981-05-26 Derivative of 4-(N-(substituted-benzylidene)amino-methyl cyclohexane-1-carboxylic acid
AU71168/81A AU542972B2 (en) 1980-06-04 1981-05-29 4-(n-(substituted-benzylidene)aminomethyl)cyclohexane-1- carboxylic acids
NO811887A NO152252C (en) 1980-06-04 1981-06-03 ANALOGY PROCEDURE FOR THE PREPARATION OF THERAPEUTICALLY EFFECTIVE DERIVATIVES OF 4- (N- (SUBSTITUTED-BENZYLIDE) AMINOMETHYL) -CYCLOHEXAN-1-CARBOXYLIC ACID
DE8181302466T DE3161771D1 (en) 1980-06-04 1981-06-03 4-(n-(substituted-benzylidene)aminomethyl)cyclohexane-1-carboxylic acids
CA000378938A CA1183150A (en) 1980-06-04 1981-06-03 Derivative of 4-[n-(substituted- benzylidene)aminomethyl]cyclohexane-1-carboxylic acid
EP81302466A EP0041826B1 (en) 1980-06-04 1981-06-03 4-(n-(substituted-benzylidene)aminomethyl)cyclohexane-1-carboxylic acids
DK248181A DK149769C (en) 1980-06-04 1981-06-04 METHOD OF ANALOGY FOR THE PREPARATION OF TRANS-4- (N- (SUBSTITUTED-BENZYLIDE) AMINOMETHYL) -CYCLOHEXAN-1-CARBOXYLIC ACID AND DERIVATIVES THEREOF

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP179081A JPS57116035A (en) 1981-01-09 1981-01-09 Novel benzylideneaminocarboxylic acid derivative and its preparation

Publications (1)

Publication Number Publication Date
JPS57116035A true JPS57116035A (en) 1982-07-19

Family

ID=11511364

Family Applications (1)

Application Number Title Priority Date Filing Date
JP179081A Pending JPS57116035A (en) 1980-06-04 1981-01-09 Novel benzylideneaminocarboxylic acid derivative and its preparation

Country Status (1)

Country Link
JP (1) JPS57116035A (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0585130A3 (en) * 1992-08-27 1994-06-08 Shiseido Co Ltd External preparation for skin containing a depigmentation agent

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0585130A3 (en) * 1992-08-27 1994-06-08 Shiseido Co Ltd External preparation for skin containing a depigmentation agent

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