JPS54100333A - Benzyl alcohol derivative and its preparation - Google Patents

Benzyl alcohol derivative and its preparation

Info

Publication number
JPS54100333A
JPS54100333A JP553378A JP553378A JPS54100333A JP S54100333 A JPS54100333 A JP S54100333A JP 553378 A JP553378 A JP 553378A JP 553378 A JP553378 A JP 553378A JP S54100333 A JPS54100333 A JP S54100333A
Authority
JP
Japan
Prior art keywords
formula
derivative
benzyl alcohol
methyl
acid addition
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP553378A
Other languages
Japanese (ja)
Other versions
JPS609704B2 (en
Inventor
Munekatsu Ikezaki
Takeshi Kanno
Hajime Iwai
Masanori Inamasu
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Tanabe Seiyaku Co Ltd
Original Assignee
Tanabe Seiyaku Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Tanabe Seiyaku Co Ltd filed Critical Tanabe Seiyaku Co Ltd
Priority to JP553378A priority Critical patent/JPS609704B2/en
Priority to US05/928,431 priority patent/US4490392A/en
Priority to DE19782834107 priority patent/DE2834107A1/en
Priority to CH837978A priority patent/CH636076A5/en
Priority to NL787808303A priority patent/NL7808303A/en
Priority to GB7832805A priority patent/GB2002765B/en
Priority to FR7823588A priority patent/FR2400005A1/en
Priority to IT68891/78A priority patent/IT1160586B/en
Publication of JPS54100333A publication Critical patent/JPS54100333A/en
Publication of JPS609704B2 publication Critical patent/JPS609704B2/en
Expired legal-status Critical Current

Links

Landscapes

  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

NEW MATERIAL:A benzyl alcohol derivative of formula I: (R1 and R2 are the same or different lower alkyl groups; n is an integer 1W3) or its pharmacologically acceptable acid addition salt.
EXAMPLE: α-[(α-Methyl-3,4-dimethoxyphenethyl-amino)methyl]-2-methoxybenzyl alcohol.
USE: Pharmaceuticals having improved hypoglycemic action and an anti-agglutination action on the blood platelet.
PROCESS: A phenylglyoxal derivative of formula II or its hydrate is condensed with an amino compound of formula III to give an α-substituted iminoacetophenone derivative of formula IV, whose carbonyl group and C=N double bond are reduced to hydroxymethylene group and C-N single bond to form the desired compound of formula I. The resulting compound is converted to an acid addition salt, if necessary.
COPYRIGHT: (C)1979,JPO&Japio
JP553378A 1977-08-11 1978-01-20 Benzyl alcohol derivative and its production method Expired JPS609704B2 (en)

Priority Applications (8)

Application Number Priority Date Filing Date Title
JP553378A JPS609704B2 (en) 1978-01-20 1978-01-20 Benzyl alcohol derivative and its production method
US05/928,431 US4490392A (en) 1977-08-11 1978-07-27 Benzylalcohol derivative and process for preparing
DE19782834107 DE2834107A1 (en) 1977-08-11 1978-08-03 BENZYL ALCOHOL DERIVATIVES, THE PROCESS FOR THEIR MANUFACTURING AND THE PHARMACEUTICAL PRODUCTS CONTAINING THEM
CH837978A CH636076A5 (en) 1977-08-11 1978-08-07 BENZYL ALCOHOL DERIVATIVES AND METHOD FOR THE PRODUCTION THEREOF.
NL787808303A NL7808303A (en) 1977-08-11 1978-08-08 BENZYL ALCOHOL DERIVATIVES WITH BLOOD SUGAR MIRROR REDUCED ACTION, AS WELL AS PHARMACEUTICAL PREPARATIONS CONTAINING THESE COMPONENTS AS AN ACTIVE COMPONENT.
GB7832805A GB2002765B (en) 1977-08-11 1978-08-09 Benzylalcohol derivative and process for preparing the same
FR7823588A FR2400005A1 (en) 1977-08-11 1978-08-10 BENZYL ALCOHOL DERIVATIVES, THEIR MANUFACTURING PROCESS AND THEIR APPLICATION AS MEDICINAL PRODUCTS
IT68891/78A IT1160586B (en) 1977-08-11 1978-08-10 BENZYL ALCOHOLIC DERIVATIVES AND PROCEDURE FOR THEIR PREPARATION

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP553378A JPS609704B2 (en) 1978-01-20 1978-01-20 Benzyl alcohol derivative and its production method

Publications (2)

Publication Number Publication Date
JPS54100333A true JPS54100333A (en) 1979-08-08
JPS609704B2 JPS609704B2 (en) 1985-03-12

Family

ID=11613816

Family Applications (1)

Application Number Title Priority Date Filing Date
JP553378A Expired JPS609704B2 (en) 1977-08-11 1978-01-20 Benzyl alcohol derivative and its production method

Country Status (1)

Country Link
JP (1) JPS609704B2 (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS62151106U (en) * 1986-03-19 1987-09-25

Also Published As

Publication number Publication date
JPS609704B2 (en) 1985-03-12

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