JPS54100333A - Benzyl alcohol derivative and its preparation - Google Patents
Benzyl alcohol derivative and its preparationInfo
- Publication number
- JPS54100333A JPS54100333A JP553378A JP553378A JPS54100333A JP S54100333 A JPS54100333 A JP S54100333A JP 553378 A JP553378 A JP 553378A JP 553378 A JP553378 A JP 553378A JP S54100333 A JPS54100333 A JP S54100333A
- Authority
- JP
- Japan
- Prior art keywords
- formula
- derivative
- benzyl alcohol
- methyl
- acid addition
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Landscapes
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
NEW MATERIAL:A benzyl alcohol derivative of formula I: (R1 and R2 are the same or different lower alkyl groups; n is an integer 1W3) or its pharmacologically acceptable acid addition salt.
EXAMPLE: α-[(α-Methyl-3,4-dimethoxyphenethyl-amino)methyl]-2-methoxybenzyl alcohol.
USE: Pharmaceuticals having improved hypoglycemic action and an anti-agglutination action on the blood platelet.
PROCESS: A phenylglyoxal derivative of formula II or its hydrate is condensed with an amino compound of formula III to give an α-substituted iminoacetophenone derivative of formula IV, whose carbonyl group and C=N double bond are reduced to hydroxymethylene group and C-N single bond to form the desired compound of formula I. The resulting compound is converted to an acid addition salt, if necessary.
COPYRIGHT: (C)1979,JPO&Japio
Priority Applications (8)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP553378A JPS609704B2 (en) | 1978-01-20 | 1978-01-20 | Benzyl alcohol derivative and its production method |
US05/928,431 US4490392A (en) | 1977-08-11 | 1978-07-27 | Benzylalcohol derivative and process for preparing |
DE19782834107 DE2834107A1 (en) | 1977-08-11 | 1978-08-03 | BENZYL ALCOHOL DERIVATIVES, THE PROCESS FOR THEIR MANUFACTURING AND THE PHARMACEUTICAL PRODUCTS CONTAINING THEM |
CH837978A CH636076A5 (en) | 1977-08-11 | 1978-08-07 | BENZYL ALCOHOL DERIVATIVES AND METHOD FOR THE PRODUCTION THEREOF. |
NL787808303A NL7808303A (en) | 1977-08-11 | 1978-08-08 | BENZYL ALCOHOL DERIVATIVES WITH BLOOD SUGAR MIRROR REDUCED ACTION, AS WELL AS PHARMACEUTICAL PREPARATIONS CONTAINING THESE COMPONENTS AS AN ACTIVE COMPONENT. |
GB7832805A GB2002765B (en) | 1977-08-11 | 1978-08-09 | Benzylalcohol derivative and process for preparing the same |
FR7823588A FR2400005A1 (en) | 1977-08-11 | 1978-08-10 | BENZYL ALCOHOL DERIVATIVES, THEIR MANUFACTURING PROCESS AND THEIR APPLICATION AS MEDICINAL PRODUCTS |
IT68891/78A IT1160586B (en) | 1977-08-11 | 1978-08-10 | BENZYL ALCOHOLIC DERIVATIVES AND PROCEDURE FOR THEIR PREPARATION |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP553378A JPS609704B2 (en) | 1978-01-20 | 1978-01-20 | Benzyl alcohol derivative and its production method |
Publications (2)
Publication Number | Publication Date |
---|---|
JPS54100333A true JPS54100333A (en) | 1979-08-08 |
JPS609704B2 JPS609704B2 (en) | 1985-03-12 |
Family
ID=11613816
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP553378A Expired JPS609704B2 (en) | 1977-08-11 | 1978-01-20 | Benzyl alcohol derivative and its production method |
Country Status (1)
Country | Link |
---|---|
JP (1) | JPS609704B2 (en) |
Families Citing this family (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS62151106U (en) * | 1986-03-19 | 1987-09-25 |
-
1978
- 1978-01-20 JP JP553378A patent/JPS609704B2/en not_active Expired
Also Published As
Publication number | Publication date |
---|---|
JPS609704B2 (en) | 1985-03-12 |
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