JPS5679668A - 1,4-dihydro-4-oxonicotinic acid derivatice and its preparation - Google Patents
1,4-dihydro-4-oxonicotinic acid derivatice and its preparationInfo
- Publication number
- JPS5679668A JPS5679668A JP15423979A JP15423979A JPS5679668A JP S5679668 A JPS5679668 A JP S5679668A JP 15423979 A JP15423979 A JP 15423979A JP 15423979 A JP15423979 A JP 15423979A JP S5679668 A JPS5679668 A JP S5679668A
- Authority
- JP
- Japan
- Prior art keywords
- dihydro
- formula
- alkyl
- derivatice
- preparation
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Abstract
NEW MATERIAL:A 1,4-dihydro-4-oxonicotinic acid derivative shown by the formula I [R1 and R4 are alkyl, (un)substituted heterocylcic group; R2 is H, alkali metal, or alkyl; R3 and R5 are the same as R1 and R3; R3 and R4 form -(CH2)n-(n is 3 or 4)].
EXAMPLE: Methyl-2,6-dimethyl-1,4-dihydro-4-oxonicotinate.
USE: An intermediate for an antibacterial compound (e.g., half synthetic penicillin, etc.) useful as a drug or agricultural chemical. A half synthetic penicillin has a strong antibracerial action.
PROCESS: A β-keto ester shown by the formula II (R6 is lower alkyl) is reacted with an enamine compound shown by the formula III under heating in an inert solvent in the presence of Molecular Sieves, to give a compound shown by the formula I.
COPYRIGHT: (C)1981,JPO&Japio
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP15423979A JPS5679668A (en) | 1979-11-30 | 1979-11-30 | 1,4-dihydro-4-oxonicotinic acid derivatice and its preparation |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP15423979A JPS5679668A (en) | 1979-11-30 | 1979-11-30 | 1,4-dihydro-4-oxonicotinic acid derivatice and its preparation |
Publications (1)
Publication Number | Publication Date |
---|---|
JPS5679668A true JPS5679668A (en) | 1981-06-30 |
Family
ID=15579876
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP15423979A Pending JPS5679668A (en) | 1979-11-30 | 1979-11-30 | 1,4-dihydro-4-oxonicotinic acid derivatice and its preparation |
Country Status (1)
Country | Link |
---|---|
JP (1) | JPS5679668A (en) |
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4964896A (en) * | 1980-05-12 | 1990-10-23 | Monsanto Company | Certain-2,6-diphenyl-1,4-dihydro-4-oxo-nicotinates which are useful for inducing male sterility in cereal grain plants |
CN110622973A (en) * | 2019-11-06 | 2019-12-31 | 海南大学 | Application of 1-aryl-4-pyridone compounds |
-
1979
- 1979-11-30 JP JP15423979A patent/JPS5679668A/en active Pending
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4964896A (en) * | 1980-05-12 | 1990-10-23 | Monsanto Company | Certain-2,6-diphenyl-1,4-dihydro-4-oxo-nicotinates which are useful for inducing male sterility in cereal grain plants |
CN110622973A (en) * | 2019-11-06 | 2019-12-31 | 海南大学 | Application of 1-aryl-4-pyridone compounds |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
DE69118765D1 (en) | Process for the preparation of an N-phenylacetyl derivative of tetrahydrothieno [3,2-c] pyridine and intermediate of synthesis | |
MA21878A1 (en) | PROCESS FOR THE PREPARATION OF PHENY - LACETIC DERIVATIVES OF THIENO-PYRIDINES AND INTERMEDIATE & -BROMO PHENYL ACIDS. | |
JPS5690031A (en) | Preparation of aromatic aldehyde | |
IE39602B1 (en) | New alkoxyalkyl-1,4-dihydropyridines, their preparation, and their medicinal use | |
JPS5679668A (en) | 1,4-dihydro-4-oxonicotinic acid derivatice and its preparation | |
JPS5746988A (en) | Novel penicillin derivative and its preparation | |
JPS57192340A (en) | Isoprenylamine derivative | |
JPS57159777A (en) | 4-hydroxycyclopentenone compound and its preparation | |
JPS5772981A (en) | 1,8-naphthyridine derivative and its salt | |
JPS56122397A (en) | Marcolides | |
JPS5576871A (en) | Chromanyloxy fatty acid homolog | |
JPS5643287A (en) | Preparation of cephamycin derivative | |
JPS56108743A (en) | 3-nitro-2-hydroxy-4-phenylbutyric acid derivative, its ester and preparation thereof | |
JPS57131792A (en) | Novel 2-oxabicyclo(2.2.2)octan-3-one derivative | |
JPS5799572A (en) | Hydroxyimidazole derivative and its preparation | |
JPS57156447A (en) | Ether compound and its synthesis | |
JPS55120591A (en) | Phosphinoethylmalonic acid derivative, and preparation thereof | |
JPS57179174A (en) | Novel aminocyclitol and its preparation | |
JPS5527142A (en) | Novel 1-phthalazone derivative | |
JPS5585568A (en) | Quinolinone-imine derivative and its preparation | |
JPS5422363A (en) | Preparation of thiophene-substituted fatty acid halide | |
JPS5452068A (en) | 2-azetidinone derivative and its preparation | |
JPS56127334A (en) | Preparation of 2-oxo-5-vinylcyclopentanecarboxylic ester and its 1-alkyl substitution product | |
JPS55122754A (en) | Alpha-benzoylureidphenylacetic acid derivative | |
JPS54106457A (en) | 2-azetidinone derivative and its preparation |