JPS54106457A - 2-azetidinone derivative and its preparation - Google Patents

2-azetidinone derivative and its preparation

Info

Publication number
JPS54106457A
JPS54106457A JP1379178A JP1379178A JPS54106457A JP S54106457 A JPS54106457 A JP S54106457A JP 1379178 A JP1379178 A JP 1379178A JP 1379178 A JP1379178 A JP 1379178A JP S54106457 A JPS54106457 A JP S54106457A
Authority
JP
Japan
Prior art keywords
aralkyl
alkyl
alkenyl
aryl
useful
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP1379178A
Other languages
Japanese (ja)
Inventor
Tadashi Hirata
Akira Sato
Yoshihiro Nakamizo
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
KH Neochem Co Ltd
Original Assignee
Kyowa Hakko Kogyo Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kyowa Hakko Kogyo Co Ltd filed Critical Kyowa Hakko Kogyo Co Ltd
Priority to JP1379178A priority Critical patent/JPS54106457A/en
Priority to CA000312398A priority patent/CA1145347A/en
Priority to FR7827889A priority patent/FR2404632A1/en
Priority to GB7838626A priority patent/GB2006195B/en
Priority to DE19782842466 priority patent/DE2842466A1/en
Publication of JPS54106457A publication Critical patent/JPS54106457A/en
Priority to US06/142,542 priority patent/US4322345A/en
Pending legal-status Critical Current

Links

Abstract

NEW MATERIAL:A compound I (R1 is H, OH, alkoxy, amino, etc.; R2 is alkyl, aralkyl; R3 is alkyl, aryl, aralkyl, alkenyl, alkynyl, etc.; R4 is alkyl, alkenyl, aryl, aralkyl.).
EXAMPLE: (4S)-t-butyl-α-(4-benzyloxycarbonyl-2-oxoazetidin-1-yl)-α-(acetyl) acetamide.
USE: β-Lactamase-inhibiting agent which is expected to be useful as a remedy for infectious diseases by using together with an antibiotic such as penicillin, etc. It is also useful as a synthetic intermediate of a sleleton of β-lactamase antibiotics.
PROCESS: The compound I is prepared by reacting an aspartic acid derivative II with an aldehyde III and an isonitrile IV in an inert solvent at +150W-50°C, pref. 0W50°C.
COPYRIGHT: (C)1979,JPO&Japio
JP1379178A 1977-09-30 1978-02-09 2-azetidinone derivative and its preparation Pending JPS54106457A (en)

Priority Applications (6)

Application Number Priority Date Filing Date Title
JP1379178A JPS54106457A (en) 1978-02-09 1978-02-09 2-azetidinone derivative and its preparation
CA000312398A CA1145347A (en) 1977-09-30 1978-09-29 2-azetidinone derivatives
FR7827889A FR2404632A1 (en) 1977-09-30 1978-09-29 NEW AZETIDINONE DERIVATIVES AND THEIR MANUFACTURING PROCEDURES
GB7838626A GB2006195B (en) 1977-09-30 1978-09-29 2-azetidinone derivatives
DE19782842466 DE2842466A1 (en) 1977-09-30 1978-09-29 2-AZETIDINONE DERIVATIVES AND PROCESS FOR THEIR PRODUCTION
US06/142,542 US4322345A (en) 1977-09-30 1980-04-21 2-Azetidinone 4-carboxy derivatives and a process for producing the same

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP1379178A JPS54106457A (en) 1978-02-09 1978-02-09 2-azetidinone derivative and its preparation

Publications (1)

Publication Number Publication Date
JPS54106457A true JPS54106457A (en) 1979-08-21

Family

ID=11843064

Family Applications (1)

Application Number Title Priority Date Filing Date
JP1379178A Pending JPS54106457A (en) 1977-09-30 1978-02-09 2-azetidinone derivative and its preparation

Country Status (1)

Country Link
JP (1) JPS54106457A (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2006308097A (en) * 2005-04-29 2006-11-09 Sulzer Pumpen Ag Flow machine and its sliding ring seal, sliding ring seal body component, and method of fastening sliding ring seal to flow machine

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2006308097A (en) * 2005-04-29 2006-11-09 Sulzer Pumpen Ag Flow machine and its sliding ring seal, sliding ring seal body component, and method of fastening sliding ring seal to flow machine

Similar Documents

Publication Publication Date Title
JPS57136567A (en) N-2-hydroxy-3-substituted piperidine compound
JPS57136579A (en) Thiazolylurea derivative, its preparation, and pharmaceutical composition containing the same
JPS54106457A (en) 2-azetidinone derivative and its preparation
JPS57183768A (en) 4-methyl-5-(o-carboxyphenyl)carbamoylthiazole derivative and its preparation
JPS5251331A (en) Process for preparation of unsaturated compounds
JPS5452068A (en) 2-azetidinone derivative and its preparation
JPS56103185A (en) Malonamidoxa-dethia-cephem compound
JPS54130552A (en) 2-azetidinone derivative and its preparation
JPS572278A (en) Dibenzoxazepin derivative
JPS54130553A (en) 2-azetidinone derivative and its preparation
JPS5711981A (en) Theobromine derivative and its preparation
JPS5610165A (en) Novel beta-lactam compound and its production
JPS57203053A (en) Preparation of cyanoacetic acid ester
JPS5679668A (en) 1,4-dihydro-4-oxonicotinic acid derivatice and its preparation
JPS5540631A (en) Novel beta-lactam compound and its preparation
JPS57112352A (en) Preparation of phenylacetic acid alkyl ester
JPS5446799A (en) Penicillins and cephalosporins
JPS5585568A (en) Quinolinone-imine derivative and its preparation
JPS54115354A (en) Biphenylylglycine derivative
JPS5585593A (en) Novel penicillin compound and its preparation
JPS5536411A (en) Benzylpenicillin derivative and their preparation
JPS5592363A (en) New 2-azetidinone derivative
JPS5711962A (en) Preparation of beta-lactam derivative
JPS5661352A (en) 3-oxy-beta-lactam compound
JPS55122797A (en) Novel nitrosourea derivative and its preparation