JPS57140781A - Preparation of dibenzoxepine compound - Google Patents
Preparation of dibenzoxepine compoundInfo
- Publication number
- JPS57140781A JPS57140781A JP1199582A JP1199582A JPS57140781A JP S57140781 A JPS57140781 A JP S57140781A JP 1199582 A JP1199582 A JP 1199582A JP 1199582 A JP1199582 A JP 1199582A JP S57140781 A JPS57140781 A JP S57140781A
- Authority
- JP
- Japan
- Prior art keywords
- agent
- alkyl
- compound
- oxodibenz
- dihydro
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Landscapes
- Pyrane Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
NEW MATERIAL:6,11-Dihydro-11-oxodibenz[b,e]oxepinylacetic acid ester of formula III (Z is alkyl).
EXAMPLE: 6,11-Dihydro-11-oxodibenz[b,e]oxepine-3-acetic acid methyl ester.
USE: Pharmaceuticals such as antiphlogistic agent, analgesic agent, antipyretic agent, blood platelet coagulation inhibiting agent, etc. It has excellent pharmacological characteristics and low toxicity.
PROCESS: The objective compound of formula III is prepared by condensing the novel substance of formulaIwith formaldehyde di-(lower alkyl)mercaptal-S- oxide in a proper solvent such as tetrahydrofuran in the presence of a basic catalyst and subjecting the resultant compound of formula II (R is alkyl) to conventional alcoholysis. The novel substance of formulaIcan be obtained by the oxidation, etc. of the corresponding alcohol.
COPYRIGHT: (C)1982,JPO&Japio
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP1199582A JPS603394B2 (en) | 1982-01-28 | 1982-01-28 | Manufacturing method of dibenzoxepines |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP1199582A JPS603394B2 (en) | 1982-01-28 | 1982-01-28 | Manufacturing method of dibenzoxepines |
Related Parent Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP11422274A Division JPS602309B2 (en) | 1974-10-03 | 1974-10-03 | Manufacturing method of dibenzoxepines |
Publications (2)
Publication Number | Publication Date |
---|---|
JPS57140781A true JPS57140781A (en) | 1982-08-31 |
JPS603394B2 JPS603394B2 (en) | 1985-01-28 |
Family
ID=11793160
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP1199582A Expired JPS603394B2 (en) | 1982-01-28 | 1982-01-28 | Manufacturing method of dibenzoxepines |
Country Status (1)
Country | Link |
---|---|
JP (1) | JPS603394B2 (en) |
-
1982
- 1982-01-28 JP JP1199582A patent/JPS603394B2/en not_active Expired
Also Published As
Publication number | Publication date |
---|---|
JPS603394B2 (en) | 1985-01-28 |
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