JPS57140781A - Preparation of dibenzoxepine compound - Google Patents

Preparation of dibenzoxepine compound

Info

Publication number
JPS57140781A
JPS57140781A JP1199582A JP1199582A JPS57140781A JP S57140781 A JPS57140781 A JP S57140781A JP 1199582 A JP1199582 A JP 1199582A JP 1199582 A JP1199582 A JP 1199582A JP S57140781 A JPS57140781 A JP S57140781A
Authority
JP
Japan
Prior art keywords
agent
alkyl
compound
oxodibenz
dihydro
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP1199582A
Other languages
Japanese (ja)
Other versions
JPS603394B2 (en
Inventor
Sadakatsu Shimada
Sotaro Kotake
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Daiichi Pharmaceutical Co Ltd
Original Assignee
Daiichi Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Daiichi Pharmaceutical Co Ltd filed Critical Daiichi Pharmaceutical Co Ltd
Priority to JP1199582A priority Critical patent/JPS603394B2/en
Publication of JPS57140781A publication Critical patent/JPS57140781A/en
Publication of JPS603394B2 publication Critical patent/JPS603394B2/en
Expired legal-status Critical Current

Links

Landscapes

  • Pyrane Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

NEW MATERIAL:6,11-Dihydro-11-oxodibenz[b,e]oxepinylacetic acid ester of formula III (Z is alkyl).
EXAMPLE: 6,11-Dihydro-11-oxodibenz[b,e]oxepine-3-acetic acid methyl ester.
USE: Pharmaceuticals such as antiphlogistic agent, analgesic agent, antipyretic agent, blood platelet coagulation inhibiting agent, etc. It has excellent pharmacological characteristics and low toxicity.
PROCESS: The objective compound of formula III is prepared by condensing the novel substance of formulaIwith formaldehyde di-(lower alkyl)mercaptal-S- oxide in a proper solvent such as tetrahydrofuran in the presence of a basic catalyst and subjecting the resultant compound of formula II (R is alkyl) to conventional alcoholysis. The novel substance of formulaIcan be obtained by the oxidation, etc. of the corresponding alcohol.
COPYRIGHT: (C)1982,JPO&Japio
JP1199582A 1982-01-28 1982-01-28 Manufacturing method of dibenzoxepines Expired JPS603394B2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP1199582A JPS603394B2 (en) 1982-01-28 1982-01-28 Manufacturing method of dibenzoxepines

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP1199582A JPS603394B2 (en) 1982-01-28 1982-01-28 Manufacturing method of dibenzoxepines

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
JP11422274A Division JPS602309B2 (en) 1974-10-03 1974-10-03 Manufacturing method of dibenzoxepines

Publications (2)

Publication Number Publication Date
JPS57140781A true JPS57140781A (en) 1982-08-31
JPS603394B2 JPS603394B2 (en) 1985-01-28

Family

ID=11793160

Family Applications (1)

Application Number Title Priority Date Filing Date
JP1199582A Expired JPS603394B2 (en) 1982-01-28 1982-01-28 Manufacturing method of dibenzoxepines

Country Status (1)

Country Link
JP (1) JPS603394B2 (en)

Also Published As

Publication number Publication date
JPS603394B2 (en) 1985-01-28

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