ES493726A0 - Un procedimiento para la preparacion de sales y esteres, de monacolina k utiles como agentes antitlipercolesteremicos. - Google Patents

Un procedimiento para la preparacion de sales y esteres, de monacolina k utiles como agentes antitlipercolesteremicos.

Info

Publication number
ES493726A0
ES493726A0 ES493726A ES493726A ES493726A0 ES 493726 A0 ES493726 A0 ES 493726A0 ES 493726 A ES493726 A ES 493726A ES 493726 A ES493726 A ES 493726A ES 493726 A0 ES493726 A0 ES 493726A0
Authority
ES
Spain
Prior art keywords
antitlipercolesteremic
monacoline
esters
salts
agents
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
ES493726A
Other languages
English (en)
Other versions
ES8105781A1 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sankyo Co Ltd
Original Assignee
Sankyo Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from JP9581479A external-priority patent/JPS5621594A/ja
Priority claimed from JP12346179A external-priority patent/JPS5646841A/ja
Application filed by Sankyo Co Ltd filed Critical Sankyo Co Ltd
Publication of ES493726A0 publication Critical patent/ES493726A0/es
Publication of ES8105781A1 publication Critical patent/ES8105781A1/es
Expired legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C59/00Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C59/40Unsaturated compounds
    • C07C59/42Unsaturated compounds containing hydroxy or O-metal groups
    • C07C59/46Unsaturated compounds containing hydroxy or O-metal groups containing rings other than six-membered aromatic rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C69/00Esters of carboxylic acids; Esters of carbonic or haloformic acids
    • C07C69/66Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety
    • C07C69/73Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety of unsaturated acids
    • C07C69/732Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety of unsaturated acids of unsaturated hydroxy carboxylic acids
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02EREDUCTION OF GREENHOUSE GAS [GHG] EMISSIONS, RELATED TO ENERGY GENERATION, TRANSMISSION OR DISTRIBUTION
    • Y02E50/00Technologies for the production of fuel of non-fossil origin
    • Y02E50/10Biofuels, e.g. bio-diesel

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
ES493726A 1979-07-27 1980-07-24 Un procedimiento para la preparacion de sales y esteres, de monacolina k utiles como agentes antitlipercolesteremicos. Expired ES8105781A1 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP9581479A JPS5621594A (en) 1979-07-27 1979-07-27 Mb-530b carboxylic acid metal salt and its preparation
JP12346179A JPS5646841A (en) 1979-09-26 1979-09-26 Mb-530b carboxylic acid ester and its preparation

Publications (2)

Publication Number Publication Date
ES493726A0 true ES493726A0 (es) 1981-06-16
ES8105781A1 ES8105781A1 (es) 1981-06-16

Family

ID=26436995

Family Applications (1)

Application Number Title Priority Date Filing Date
ES493726A Expired ES8105781A1 (es) 1979-07-27 1980-07-24 Un procedimiento para la preparacion de sales y esteres, de monacolina k utiles como agentes antitlipercolesteremicos.

Country Status (16)

Country Link
AT (1) AT375334B (es)
AU (1) AU6083980A (es)
CH (1) CH647749A5 (es)
DD (1) DD153827A5 (es)
DE (1) DE3028284A1 (es)
DK (1) DK322380A (es)
ES (1) ES8105781A1 (es)
FI (1) FI71300C (es)
FR (1) FR2462417A1 (es)
GB (1) GB2055100A (es)
IT (1) IT1147763B (es)
NL (1) NL8004303A (es)
NO (1) NO156210C (es)
NZ (1) NZ194445A (es)
PL (1) PL225901A1 (es)
SE (1) SE445828B (es)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1327360C (en) * 1983-11-14 1994-03-01 William F. Hoffman Oxo-analogs of mevinolin-like antihypercholesterolemic agents
CA1282425C (en) * 1984-06-04 1991-04-02 Meyer Sletzinger Process for preparing hmg-coa reductase inhibitors with a 3,5-dihydroxypentanoate subunit
EP0204287A3 (en) * 1985-06-04 1987-07-01 Merck & Co. Inc. Process for the preparation of hmg-coa reductase inhibitors with a 3,5-dihydroxypentanoate subunit
US4611081A (en) * 1985-07-05 1986-09-09 Merck & Co., Inc. Process for the preparation of HMG-CoA reductase inhibitors intermediates
USRE33033E (en) * 1985-07-05 1989-08-22 Merck & Co., Inc. Process for the preparation of HMG-CoA reductase inhibitors intermediates
US7238348B2 (en) 1996-09-30 2007-07-03 Beijing Peking University Wbl Corporation Ltd. Method of treatment of osteoporosis with compositions of red rice fermentation products
US6046022A (en) 1996-09-30 2000-04-04 Peking University Methods and compositions employing red rice fermentation products
JP2002518448A (ja) * 1998-06-24 2002-06-25 メルク エンド カムパニー インコーポレーテッド 高血中コレステロールを治療する組成物および方法
SI20070A (sl) 1998-09-18 2000-04-30 LEK, tovarna farmacevtskih in kemi�nih izdelkov, d.d. Nove soli inhibitorjev HMG-CoA reduktaze
SI1292293T1 (en) * 2000-06-09 2004-06-30 LEK farmacevtska dru�ba d.d. Stabilized pharmaceutically effective composition and pharmaceutical formulation comprising the same
US6806290B2 (en) 2000-06-09 2004-10-19 Lek Pharmaceuticals D.D. Stabilized pharmaceutically effective composition and pharmaceutical formulation comprising the same
AU2001288724A1 (en) * 2000-09-06 2002-03-22 Merck & Co., Inc. Dihydroxy open-acid salt of simvastatin
JP2005500282A (ja) 2001-06-13 2005-01-06 ランバクシー ラボラトリーズ リミテッド 新規なHMG−CoAレダクターゼ抑制剤としてのシムバスタチンのメチル同族体
KR100379075B1 (en) 2002-03-07 2003-04-08 Jinis Biopharmaceuticals Co Method for producing low cholesterol animal food product and food product therefrom
US8158362B2 (en) 2005-03-30 2012-04-17 Decode Genetics Ehf. Methods of diagnosing susceptibility to myocardial infarction and screening for an LTA4H haplotype
CN101659923B (zh) * 2008-08-26 2011-10-26 北京北大维信生物科技有限公司 一种制备开环式洛伐他汀的方法

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4137322A (en) * 1976-11-02 1979-01-30 Sankyo Company Limited ML-236B carboxylic acid derivatives and their use as antihyperlipemic agents
JPS55150898A (en) * 1979-05-11 1980-11-25 Sankyo Co Ltd Preparation of a new physiologically active substance mb-530b

Also Published As

Publication number Publication date
GB2055100A (en) 1981-02-25
NL8004303A (nl) 1981-01-29
DE3028284A1 (de) 1981-02-19
FR2462417B1 (es) 1984-01-20
FI71300B (fi) 1986-09-09
SE445828B (sv) 1986-07-21
DK322380A (da) 1981-01-28
NO156210C (no) 1987-08-12
SE8005386L (sv) 1981-01-28
AT375334B (de) 1984-07-25
PL225901A1 (es) 1982-07-19
DD153827A5 (de) 1982-02-03
IT1147763B (it) 1986-11-26
ES8105781A1 (es) 1981-06-16
FI802357A (fi) 1981-01-28
AU6083980A (en) 1981-01-29
ATA392380A (de) 1983-12-15
FI71300C (fi) 1986-12-19
DE3028284C2 (es) 1990-08-09
NZ194445A (en) 1984-07-06
NO802244L (no) 1981-01-28
IT8068211A0 (it) 1980-07-28
CH647749A5 (de) 1985-02-15
FR2462417A1 (fr) 1981-02-13
NO156210B (no) 1987-05-04

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