ES494131A0 - Un procedimiento para la preparacion de diariltiofenos. - Google Patents

Un procedimiento para la preparacion de diariltiofenos.

Info

Publication number
ES494131A0
ES494131A0 ES80494131A ES494131A ES494131A0 ES 494131 A0 ES494131 A0 ES 494131A0 ES 80494131 A ES80494131 A ES 80494131A ES 494131 A ES494131 A ES 494131A ES 494131 A0 ES494131 A0 ES 494131A0
Authority
ES
Spain
Prior art keywords
diarylthiophenes
procedure
preparation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
ES80494131A
Other languages
English (en)
Other versions
ES8106720A1 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
EIDP Inc
Original Assignee
EI Du Pont de Nemours and Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by EI Du Pont de Nemours and Co filed Critical EI Du Pont de Nemours and Co
Publication of ES494131A0 publication Critical patent/ES494131A0/es
Publication of ES8106720A1 publication Critical patent/ES8106720A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
    • C07D333/26—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D333/30—Hetero atoms other than halogen
    • C07D333/34—Sulfur atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
ES80494131A 1979-08-09 1980-08-08 Un procedimiento para la preparacion de diariltiofenos. Expired ES8106720A1 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US6506979A 1979-08-09 1979-08-09
US06/159,236 US4302461A (en) 1979-08-09 1980-06-20 Antiinflammatory 5-substituted-2,3-diarylthiophenes

Publications (2)

Publication Number Publication Date
ES494131A0 true ES494131A0 (es) 1981-09-01
ES8106720A1 ES8106720A1 (es) 1981-09-01

Family

ID=26745173

Family Applications (1)

Application Number Title Priority Date Filing Date
ES80494131A Expired ES8106720A1 (es) 1979-08-09 1980-08-08 Un procedimiento para la preparacion de diariltiofenos.

Country Status (20)

Country Link
US (1) US4302461A (es)
EP (1) EP0024042B1 (es)
AR (1) AR227288A1 (es)
AT (1) ATE17725T1 (es)
AU (1) AU533376B2 (es)
CA (1) CA1151650A (es)
DE (1) DE3071385D1 (es)
DK (1) DK301180A (es)
ES (1) ES8106720A1 (es)
FI (1) FI802506A (es)
GR (1) GR69912B (es)
HU (1) HU182185B (es)
IE (1) IE51387B1 (es)
IL (1) IL60800A (es)
MX (1) MX6600E (es)
NO (1) NO152091C (es)
NZ (1) NZ194607A (es)
PH (1) PH16821A (es)
PT (1) PT71684B (es)
YU (2) YU199880A (es)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4381311A (en) * 1980-12-29 1983-04-26 E. I. Du Pont De Nemours And Company Antiinflammatory 4,5-diaryl-α-(polyhalomethyl)-2-thiophenemethanols
EP0055471A1 (en) * 1980-12-29 1982-07-07 E.I. Du Pont De Nemours And Company Antiinflammatory 4,5-diaryl-alpha,alpha-bis(polyhalomethyl)-2-thiophenemethanamines
US4820827A (en) * 1982-03-03 1989-04-11 E. I. Du Pont De Nemours And Company 2,3-diaryl-5-bromothiophene compounds of use for the treatment of inflammaton and dysmenorrhea
US4590205A (en) * 1982-03-03 1986-05-20 E. I. Du Pont De Nemours And Company Antiinflammatory and/or analgesic 2,3-diaryl-5-halo thiophenes
EP0087629B1 (en) * 1982-03-03 1986-01-15 E.I. Du Pont De Nemours And Company Antiinflammatory and/or analgesic 2,3-diaryl-5-halo thiophenes
US4749712A (en) * 1983-03-01 1988-06-07 E. I. Du Pont De Nemours And Company Antiinflammatory and/or analgesic 5-alkylthiophenes
EP0273602A1 (en) * 1986-12-05 1988-07-06 Eli Lilly And Company 3-Cyano-4-arylthiophenes
GB9012936D0 (en) * 1990-06-11 1990-08-01 Fujisawa Pharmaceutical Co Thiophene derivatives,processes for preparation thereof and pharmaceutical composition comprising the same
US5571810A (en) * 1990-06-11 1996-11-05 Fujisawa Pharmaceutical Co., Ltd. Thiophene derivatives
US6492413B2 (en) * 1993-01-15 2002-12-10 G.D. Searle & Co. 3.4-diaryl thiophenes and analogs thereof having use as antiinflammatory agents
AU6027694A (en) * 1993-01-15 1994-08-15 G.D. Searle & Co. Novel 3,4-diaryl thiophenes and analogs thereof having use as antiinflammatory agents
US5474995A (en) 1993-06-24 1995-12-12 Merck Frosst Canada, Inc. Phenyl heterocycles as cox-2 inhibitors
WO1996026204A1 (fr) * 1995-02-24 1996-08-29 Kaken Pharmaceutical Co., Ltd. Derives de phenylamidinothiophene et agent antiphlogistique les contenant
US5691374A (en) * 1995-05-18 1997-11-25 Merck Frosst Canada Inc. Diaryl-5-oxygenated-2-(5H) -furanones as COX-2 inhibitors
WO1996038418A1 (en) 1995-06-02 1996-12-05 G.D. Searle & Co. Heterocyclo substituted hydroxamic acid derivatives as cyclooxygenase-2 and 5-lipoxygenase inhibitors
US6512121B2 (en) 1998-09-14 2003-01-28 G.D. Searle & Co. Heterocyclo substituted hydroxamic acid derivatives as cyclooxygenase-2 and 5-lipoxygenase inhibitors
US6515014B2 (en) 1995-06-02 2003-02-04 G. D. Searle & Co. Thiophene substituted hydroxamic acid derivatives as cyclooxygenase-2 and 5-lipoxygenase inhibitors
US6677364B2 (en) 1998-04-20 2004-01-13 G.D. Searle & Co. Substituted sulfonylphenylheterocycles as cyclooxygenase-2 and 5-lipoxygenase inhibitors
US20030105144A1 (en) 2001-04-17 2003-06-05 Ping Gao Stabilized oral pharmaceutical composition
US7329401B2 (en) * 2002-04-15 2008-02-12 The Regents Of The University Of California Cyclooxygenase-2 selective agents useful as imaging probes and related methods
FR2880890B1 (fr) * 2005-01-19 2007-03-30 Sanofi Aventis Sa Derives de n-[(4,5-diphenyl-2-thienyl)methyl]sulfonamide, leur preparation et leur application en therapeutique
FR2881744B1 (fr) 2005-02-09 2007-04-27 Sanofi Aventis Sa Derives de n-[(4,5-diphenyl-2-thienyl)methyl]amine, leur preparation et leur application en therapeutique
WO2006092059A1 (en) * 2005-03-04 2006-09-08 Fan Wu Design and synthesis of novel antimicrobials
CN101429189B (zh) * 2008-12-24 2014-07-23 沈阳药科大学 2，3-二取代芳基噻吩类衍生物及其用途

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2639286A (en) * 1948-07-29 1953-05-19 Universal Oil Prod Co Alkylation of heterocyclic organic compounds
US3531497A (en) * 1967-02-21 1970-09-29 Upjohn Co 2,4,5 - triphenyl - (and substituted triphenyl) - 3 - acetonitriles of pyrrole
GB1271082A (en) * 1968-05-07 1972-04-19 Wyeth John & Brother Ltd Furan, pyrrole and thiophene derivatives

Also Published As

Publication number Publication date
NO802384L (no) 1981-02-10
AR227288A1 (es) 1982-10-15
IL60800A0 (en) 1980-10-26
PH16821A (en) 1984-03-06
YU199880A (en) 1983-04-30
EP0024042B1 (en) 1986-01-29
PT71684A (en) 1980-09-01
EP0024042A1 (en) 1981-02-18
IE801668L (en) 1981-02-09
MX6600E (es) 1985-08-14
NZ194607A (en) 1984-05-31
FI802506A (fi) 1981-02-10
HU182185B (en) 1983-12-28
IL60800A (en) 1985-02-28
DE3071385D1 (en) 1986-03-13
CA1151650A (en) 1983-08-09
NO152091C (no) 1985-07-31
NO152091B (no) 1985-04-22
GR69912B (es) 1982-07-21
IE51387B1 (en) 1986-12-24
ATE17725T1 (de) 1986-02-15
DK301180A (da) 1981-02-10
AU6133480A (en) 1982-02-18
ES8106720A1 (es) 1981-09-01
AU533376B2 (en) 1983-11-17
YU5783A (en) 1983-06-30
PT71684B (en) 1982-04-06
US4302461A (en) 1981-11-24

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