ES494131A0 - Un procedimiento para la preparacion de diariltiofenos. - Google Patents
Un procedimiento para la preparacion de diariltiofenos.Info
- Publication number
- ES494131A0 ES494131A0 ES80494131A ES494131A ES494131A0 ES 494131 A0 ES494131 A0 ES 494131A0 ES 80494131 A ES80494131 A ES 80494131A ES 494131 A ES494131 A ES 494131A ES 494131 A0 ES494131 A0 ES 494131A0
- Authority
- ES
- Spain
- Prior art keywords
- diarylthiophenes
- procedure
- preparation
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
- C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
- C07D333/26—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D333/30—Hetero atoms other than halogen
- C07D333/34—Sulfur atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US6506979A | 1979-08-09 | 1979-08-09 | |
US06/159,236 US4302461A (en) | 1979-08-09 | 1980-06-20 | Antiinflammatory 5-substituted-2,3-diarylthiophenes |
Publications (2)
Publication Number | Publication Date |
---|---|
ES494131A0 true ES494131A0 (es) | 1981-09-01 |
ES8106720A1 ES8106720A1 (es) | 1981-09-01 |
Family
ID=26745173
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES80494131A Expired ES8106720A1 (es) | 1979-08-09 | 1980-08-08 | Un procedimiento para la preparacion de diariltiofenos. |
Country Status (20)
Country | Link |
---|---|
US (1) | US4302461A (es) |
EP (1) | EP0024042B1 (es) |
AR (1) | AR227288A1 (es) |
AT (1) | ATE17725T1 (es) |
AU (1) | AU533376B2 (es) |
CA (1) | CA1151650A (es) |
DE (1) | DE3071385D1 (es) |
DK (1) | DK301180A (es) |
ES (1) | ES8106720A1 (es) |
FI (1) | FI802506A (es) |
GR (1) | GR69912B (es) |
HU (1) | HU182185B (es) |
IE (1) | IE51387B1 (es) |
IL (1) | IL60800A (es) |
MX (1) | MX6600E (es) |
NO (1) | NO152091C (es) |
NZ (1) | NZ194607A (es) |
PH (1) | PH16821A (es) |
PT (1) | PT71684B (es) |
YU (2) | YU199880A (es) |
Families Citing this family (24)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4381311A (en) * | 1980-12-29 | 1983-04-26 | E. I. Du Pont De Nemours And Company | Antiinflammatory 4,5-diaryl-α-(polyhalomethyl)-2-thiophenemethanols |
EP0055471A1 (en) * | 1980-12-29 | 1982-07-07 | E.I. Du Pont De Nemours And Company | Antiinflammatory 4,5-diaryl-alpha,alpha-bis(polyhalomethyl)-2-thiophenemethanamines |
US4820827A (en) * | 1982-03-03 | 1989-04-11 | E. I. Du Pont De Nemours And Company | 2,3-diaryl-5-bromothiophene compounds of use for the treatment of inflammaton and dysmenorrhea |
US4590205A (en) * | 1982-03-03 | 1986-05-20 | E. I. Du Pont De Nemours And Company | Antiinflammatory and/or analgesic 2,3-diaryl-5-halo thiophenes |
EP0087629B1 (en) * | 1982-03-03 | 1986-01-15 | E.I. Du Pont De Nemours And Company | Antiinflammatory and/or analgesic 2,3-diaryl-5-halo thiophenes |
US4749712A (en) * | 1983-03-01 | 1988-06-07 | E. I. Du Pont De Nemours And Company | Antiinflammatory and/or analgesic 5-alkylthiophenes |
EP0273602A1 (en) * | 1986-12-05 | 1988-07-06 | Eli Lilly And Company | 3-Cyano-4-arylthiophenes |
GB9012936D0 (en) * | 1990-06-11 | 1990-08-01 | Fujisawa Pharmaceutical Co | Thiophene derivatives,processes for preparation thereof and pharmaceutical composition comprising the same |
US5571810A (en) * | 1990-06-11 | 1996-11-05 | Fujisawa Pharmaceutical Co., Ltd. | Thiophene derivatives |
US6492413B2 (en) * | 1993-01-15 | 2002-12-10 | G.D. Searle & Co. | 3.4-diaryl thiophenes and analogs thereof having use as antiinflammatory agents |
AU6027694A (en) * | 1993-01-15 | 1994-08-15 | G.D. Searle & Co. | Novel 3,4-diaryl thiophenes and analogs thereof having use as antiinflammatory agents |
US5474995A (en) | 1993-06-24 | 1995-12-12 | Merck Frosst Canada, Inc. | Phenyl heterocycles as cox-2 inhibitors |
WO1996026204A1 (fr) * | 1995-02-24 | 1996-08-29 | Kaken Pharmaceutical Co., Ltd. | Derives de phenylamidinothiophene et agent antiphlogistique les contenant |
US5691374A (en) * | 1995-05-18 | 1997-11-25 | Merck Frosst Canada Inc. | Diaryl-5-oxygenated-2-(5H) -furanones as COX-2 inhibitors |
WO1996038418A1 (en) | 1995-06-02 | 1996-12-05 | G.D. Searle & Co. | Heterocyclo substituted hydroxamic acid derivatives as cyclooxygenase-2 and 5-lipoxygenase inhibitors |
US6512121B2 (en) | 1998-09-14 | 2003-01-28 | G.D. Searle & Co. | Heterocyclo substituted hydroxamic acid derivatives as cyclooxygenase-2 and 5-lipoxygenase inhibitors |
US6515014B2 (en) | 1995-06-02 | 2003-02-04 | G. D. Searle & Co. | Thiophene substituted hydroxamic acid derivatives as cyclooxygenase-2 and 5-lipoxygenase inhibitors |
US6677364B2 (en) | 1998-04-20 | 2004-01-13 | G.D. Searle & Co. | Substituted sulfonylphenylheterocycles as cyclooxygenase-2 and 5-lipoxygenase inhibitors |
US20030105144A1 (en) | 2001-04-17 | 2003-06-05 | Ping Gao | Stabilized oral pharmaceutical composition |
US7329401B2 (en) * | 2002-04-15 | 2008-02-12 | The Regents Of The University Of California | Cyclooxygenase-2 selective agents useful as imaging probes and related methods |
FR2880890B1 (fr) * | 2005-01-19 | 2007-03-30 | Sanofi Aventis Sa | Derives de n-[(4,5-diphenyl-2-thienyl)methyl]sulfonamide, leur preparation et leur application en therapeutique |
FR2881744B1 (fr) | 2005-02-09 | 2007-04-27 | Sanofi Aventis Sa | Derives de n-[(4,5-diphenyl-2-thienyl)methyl]amine, leur preparation et leur application en therapeutique |
WO2006092059A1 (en) * | 2005-03-04 | 2006-09-08 | Fan Wu | Design and synthesis of novel antimicrobials |
CN101429189B (zh) * | 2008-12-24 | 2014-07-23 | 沈阳药科大学 | 2,3-二取代芳基噻吩类衍生物及其用途 |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US2639286A (en) * | 1948-07-29 | 1953-05-19 | Universal Oil Prod Co | Alkylation of heterocyclic organic compounds |
US3531497A (en) * | 1967-02-21 | 1970-09-29 | Upjohn Co | 2,4,5 - triphenyl - (and substituted triphenyl) - 3 - acetonitriles of pyrrole |
GB1271082A (en) * | 1968-05-07 | 1972-04-19 | Wyeth John & Brother Ltd | Furan, pyrrole and thiophene derivatives |
-
1980
- 1980-06-20 US US06/159,236 patent/US4302461A/en not_active Expired - Lifetime
- 1980-07-11 DK DK301180A patent/DK301180A/da not_active Application Discontinuation
- 1980-08-05 CA CA000357618A patent/CA1151650A/en not_active Expired
- 1980-08-06 MX MX808959U patent/MX6600E/es unknown
- 1980-08-07 AR AR282080A patent/AR227288A1/es active
- 1980-08-07 PH PH24412A patent/PH16821A/en unknown
- 1980-08-07 EP EP80104665A patent/EP0024042B1/en not_active Expired
- 1980-08-07 AT AT80104665T patent/ATE17725T1/de not_active IP Right Cessation
- 1980-08-07 DE DE8080104665T patent/DE3071385D1/de not_active Expired
- 1980-08-07 HU HU801964A patent/HU182185B/hu unknown
- 1980-08-08 IE IE1668/80A patent/IE51387B1/en not_active IP Right Cessation
- 1980-08-08 NO NO802384A patent/NO152091C/no unknown
- 1980-08-08 NZ NZ194607A patent/NZ194607A/en unknown
- 1980-08-08 IL IL60800A patent/IL60800A/xx unknown
- 1980-08-08 FI FI802606A patent/FI802506A/fi not_active Application Discontinuation
- 1980-08-08 PT PT71684A patent/PT71684B/pt unknown
- 1980-08-08 ES ES80494131A patent/ES8106720A1/es not_active Expired
- 1980-08-08 YU YU01998/80A patent/YU199880A/xx unknown
- 1980-08-09 GR GR62639A patent/GR69912B/el unknown
- 1980-08-11 AU AU61334/80A patent/AU533376B2/en not_active Ceased
-
1983
- 1983-01-11 YU YU00057/83A patent/YU5783A/xx unknown
Also Published As
Publication number | Publication date |
---|---|
NO802384L (no) | 1981-02-10 |
AR227288A1 (es) | 1982-10-15 |
IL60800A0 (en) | 1980-10-26 |
PH16821A (en) | 1984-03-06 |
YU199880A (en) | 1983-04-30 |
EP0024042B1 (en) | 1986-01-29 |
PT71684A (en) | 1980-09-01 |
EP0024042A1 (en) | 1981-02-18 |
IE801668L (en) | 1981-02-09 |
MX6600E (es) | 1985-08-14 |
NZ194607A (en) | 1984-05-31 |
FI802506A (fi) | 1981-02-10 |
HU182185B (en) | 1983-12-28 |
IL60800A (en) | 1985-02-28 |
DE3071385D1 (en) | 1986-03-13 |
CA1151650A (en) | 1983-08-09 |
NO152091C (no) | 1985-07-31 |
NO152091B (no) | 1985-04-22 |
GR69912B (es) | 1982-07-21 |
IE51387B1 (en) | 1986-12-24 |
ATE17725T1 (de) | 1986-02-15 |
DK301180A (da) | 1981-02-10 |
AU6133480A (en) | 1982-02-18 |
ES8106720A1 (es) | 1981-09-01 |
AU533376B2 (en) | 1983-11-17 |
YU5783A (en) | 1983-06-30 |
PT71684B (en) | 1982-04-06 |
US4302461A (en) | 1981-11-24 |
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