FI66847C - Foerfarande foer framstaellning av 4-hydroxi-2-oxo-pyrrolidinalkanamider - Google Patents

Foerfarande foer framstaellning av 4-hydroxi-2-oxo-pyrrolidinalkanamider Download PDF

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Publication number
FI66847C
FI66847C FI780406A FI780406A FI66847C FI 66847 C FI66847 C FI 66847C FI 780406 A FI780406 A FI 780406A FI 780406 A FI780406 A FI 780406A FI 66847 C FI66847 C FI 66847C
Authority
FI
Finland
Prior art keywords
process according
hydroxy
mixture
general formula
derivative
Prior art date
Application number
FI780406A
Other languages
English (en)
Finnish (fi)
Swedish (sv)
Other versions
FI780406A7 (fi
FI66847B (fi
Inventor
Riccardo Monguzzi
Giorgio Pifferi
Original Assignee
Isf Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Isf Spa filed Critical Isf Spa
Publication of FI780406A7 publication Critical patent/FI780406A7/fi
Application granted granted Critical
Publication of FI66847B publication Critical patent/FI66847B/fi
Publication of FI66847C publication Critical patent/FI66847C/fi

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/18—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C07D207/22—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/24—Oxygen or sulfur atoms
    • C07D207/26—2-Pyrrolidones
    • C07D207/273—2-Pyrrolidones with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to other ring carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Neurology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyrrole Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
FI780406A 1977-02-11 1978-02-08 Foerfarande foer framstaellning av 4-hydroxi-2-oxo-pyrrolidinalkanamider FI66847C (fi)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IT20226/77A IT1075564B (it) 1977-02-11 1977-02-11 Procedimento per la preparazione di derivati pirrolidinici
IT2022677 1977-02-11

Publications (3)

Publication Number Publication Date
FI780406A7 FI780406A7 (fi) 1978-08-12
FI66847B FI66847B (fi) 1984-08-31
FI66847C true FI66847C (fi) 1984-12-10

Family

ID=11164922

Family Applications (1)

Application Number Title Priority Date Filing Date
FI780406A FI66847C (fi) 1977-02-11 1978-02-08 Foerfarande foer framstaellning av 4-hydroxi-2-oxo-pyrrolidinalkanamider

Country Status (23)

Country Link
US (1) US4124594A (cs)
JP (1) JPS53101368A (cs)
AR (1) AR219734A1 (cs)
AT (1) AT362781B (cs)
CA (1) CA1083585A (cs)
CH (1) CH631703A5 (cs)
CS (1) CS214767B2 (cs)
DE (1) DE2759033C2 (cs)
DK (1) DK155279C (cs)
ES (1) ES466857A1 (cs)
FI (1) FI66847C (cs)
GB (1) GB1588074A (cs)
HU (1) HU178588B (cs)
IN (1) IN147764B (cs)
IT (1) IT1075564B (cs)
MX (1) MX4988E (cs)
NL (1) NL187207C (cs)
NO (1) NO147751C (cs)
PL (1) PL108024B1 (cs)
PT (1) PT67641B (cs)
SE (1) SE428208B (cs)
SU (1) SU984407A3 (cs)
YU (1) YU40322B (cs)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2858573A (en) * 1958-11-04 Fibers
IT1141287B (it) * 1979-06-13 1986-10-01 Nattermann A & Cie Ammidi di acidi pirrolidin-(2)-on-(1)-ilalchil-carbossilici,procedimento per la loro preparazione e prodotti medicinali che le contengono
FR2515179A1 (fr) * 1981-07-24 1983-04-29 Hoffmann La Roche Derives de pyrrolidine, leur procede de preparation, les intermediaires pour leur synthese et leur application therapeutique
IT1206699B (it) * 1984-02-27 1989-04-27 Isf Spa Procedimento per preparare derivati di pirrolidone.
IT1173768B (it) * 1984-04-02 1987-06-24 Isf Spa Procedimento di preparazione di derivati 1-carbamoilmetilici di 4-idrossi-2-osso-pirrolidina nonche' di intermedi per ottenere tali composti
CH666483A5 (de) * 1985-01-16 1988-07-29 Lonza Ag Verfahren zur herstellung von thiotetronsaeure.
IT1190378B (it) * 1985-06-21 1988-02-16 Isf Spa Derivati pirrolidonici
US4686296A (en) * 1985-07-26 1987-08-11 Denki Kagaku Kogyo Kabushiki Kaisha Process for producing oxiracetam
CH668423A5 (de) * 1986-06-19 1988-12-30 Lonza Ag Verfahren zur herstellung von 4-alkoxy-3-pyrrolin-2-onen.
IL80071A0 (en) * 1985-09-24 1986-12-31 Lonza Ag Pyrrolidine acetamide derivatives
HU195773B (en) * 1985-09-24 1988-07-28 Lonza Ag Process for preparing alkyl esters of 4-alkoxy-3-pyrrolin-2-on-1-yl-acetic acid
CH668424A5 (de) * 1986-06-26 1988-12-30 Lonza Ag 4-benzyloxy-3-pyrrolin-2-on-l-yl-acetamid, dessen herstellung und verwendung.
CH668422A5 (de) * 1986-06-26 1988-12-30 Lonza Ag 4-benzyloxy-3-pyrrolin-2-on, dessen herstellung und verwendung zur synthese von tetramsaeure.
CH667655A5 (de) * 1986-09-24 1988-10-31 Lonza Ag Verfahren zur herstellung von 4-alkoxy-2(5h)-thiophenonen.
CH670644A5 (cs) * 1986-12-18 1989-06-30 Lonza Ag
EP0358128B1 (de) * 1988-09-06 1995-06-28 Lonza Ag Verfahren zur Herstellung von 5-Alkyltetramsäuren
FI95034C (fi) * 1989-03-15 1995-12-11 Lonza Ag Menetelmä 1,3-substituoidun tetrahydro-1H-tieno/3,4-d/-imidatsol-2(3H)-on-4-ylideenipentaanihappoesterin valmistamiseksi
CH680293A5 (cs) * 1990-06-26 1992-07-31 Lonza Ag
CN101704778B (zh) * 2009-09-30 2012-10-17 厦门市华兴化工有限公司 一种制备4-羟基吡咯烷酮-2-乙酰胺的方法
WO2011143872A1 (zh) * 2010-05-21 2011-11-24 重庆润泽医疗器械有限公司 一种(s)-4-羟基-2-氧代-1-吡咯烷乙酰胺晶型及其制备方法和用途
EP3530271A4 (en) 2016-10-24 2020-03-25 Chongqing Runze Pharmaceutical Company Limited CRYSTALLINE FORM II OF DEXTRAL-OXIRACETAM, PROCESS FOR THE PREPARATION THEREOF AND USE THEREOF
US10556863B1 (en) 2016-10-24 2020-02-11 Chongqing Ruzer Pharmaceutical Company Limited Crystalline form of (R)-4-hydroxy-2-oxo-1-pyrrolidineacetamide, preparation method therefor and use thereof
EP3530272A4 (en) 2016-10-24 2020-03-25 Chongqing Runze Pharmaceutical Company Limited INNOVATIVE CRYSTALLINE FORM OF DEXTRALOXIRACETAM, PRODUCTION METHOD THEREFOR AND USE THEREOF
CN108299267A (zh) 2017-01-12 2018-07-20 重庆润泽医药有限公司 (r)-4-羟基-2-氧-1-吡咯烷乙酰胺的晶型及其制备方法和用途
CN108299268A (zh) * 2017-01-12 2018-07-20 重庆润泽医药有限公司 一种(r)-4-羟基-2-氧-1-吡咯烷乙酰胺晶型的制备方法

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ181727A (en) 1975-08-13 1978-03-06 Isf Spa Pyrroline-2-one derivatives and pharmaceutical compositions
IT1045043B (it) * 1975-08-13 1980-04-21 Isf Spa Derivati pirrolidinici

Also Published As

Publication number Publication date
IN147764B (cs) 1980-06-21
YU30378A (en) 1982-10-31
SU984407A3 (ru) 1982-12-23
SE7801537L (sv) 1978-08-12
NO147751C (no) 1983-06-08
DK155279B (da) 1989-03-20
DE2759033A1 (de) 1978-08-17
ATA88778A (de) 1980-11-15
AR219734A1 (es) 1980-09-15
CS214767B2 (en) 1982-05-28
GB1588074A (en) 1981-04-15
PL108024B1 (pl) 1980-03-31
JPS53101368A (en) 1978-09-04
DE2759033C2 (de) 1984-04-19
MX4988E (es) 1983-01-31
PL204550A1 (pl) 1978-12-04
NL187207B (nl) 1991-02-01
CH631703A5 (de) 1982-08-31
NO780463L (no) 1978-08-14
HU178588B (en) 1982-05-28
PT67641B (de) 1980-03-03
SE428208B (sv) 1983-06-13
YU40322B (en) 1985-12-31
FI780406A7 (fi) 1978-08-12
CA1083585A (en) 1980-08-12
IT1075564B (it) 1985-04-22
ES466857A1 (es) 1978-10-01
FI66847B (fi) 1984-08-31
NL7801501A (nl) 1978-08-15
AT362781B (de) 1981-06-10
DK155279C (da) 1989-07-24
NL187207C (nl) 1991-07-01
NO147751B (no) 1983-02-28
JPS6338349B2 (cs) 1988-07-29
US4124594A (en) 1978-11-07
DK63078A (da) 1978-08-12
PT67641A (de) 1978-03-01

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Owner name: I.S.F SOCIETA PER AZIONI