ES466857A1 - Procedimiento para la preparacion de derivados pirrolidini- cos. - Google Patents

Procedimiento para la preparacion de derivados pirrolidini- cos.

Info

Publication number
ES466857A1
ES466857A1 ES466857A ES466857A ES466857A1 ES 466857 A1 ES466857 A1 ES 466857A1 ES 466857 A ES466857 A ES 466857A ES 466857 A ES466857 A ES 466857A ES 466857 A1 ES466857 A1 ES 466857A1
Authority
ES
Spain
Prior art keywords
acid
derivative
onyl
amides
hydroxy pyrrolidin
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES466857A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
ISF SpA
Original Assignee
ISF SpA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by ISF SpA filed Critical ISF SpA
Publication of ES466857A1 publication Critical patent/ES466857A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/18—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C07D207/22—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/24—Oxygen or sulfur atoms
    • C07D207/26—2-Pyrrolidones
    • C07D207/273—2-Pyrrolidones with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to other ring carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Neurology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyrrole Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
ES466857A 1977-02-11 1978-02-10 Procedimiento para la preparacion de derivados pirrolidini- cos. Expired ES466857A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT20226/77A IT1075564B (it) 1977-02-11 1977-02-11 Procedimento per la preparazione di derivati pirrolidinici

Publications (1)

Publication Number Publication Date
ES466857A1 true ES466857A1 (es) 1978-10-01

Family

ID=11164922

Family Applications (1)

Application Number Title Priority Date Filing Date
ES466857A Expired ES466857A1 (es) 1977-02-11 1978-02-10 Procedimiento para la preparacion de derivados pirrolidini- cos.

Country Status (23)

Country Link
US (1) US4124594A (es)
JP (1) JPS53101368A (es)
AR (1) AR219734A1 (es)
AT (1) AT362781B (es)
CA (1) CA1083585A (es)
CH (1) CH631703A5 (es)
CS (1) CS214767B2 (es)
DE (1) DE2759033C2 (es)
DK (1) DK155279C (es)
ES (1) ES466857A1 (es)
FI (1) FI66847C (es)
GB (1) GB1588074A (es)
HU (1) HU178588B (es)
IN (1) IN147764B (es)
IT (1) IT1075564B (es)
MX (1) MX4988E (es)
NL (1) NL187207C (es)
NO (1) NO147751C (es)
PL (1) PL108024B1 (es)
PT (1) PT67641B (es)
SE (1) SE428208B (es)
SU (1) SU984407A3 (es)
YU (1) YU40322B (es)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2858573A (en) * 1958-11-04 Fibers
IT1141287B (it) * 1979-06-13 1986-10-01 Nattermann A & Cie Ammidi di acidi pirrolidin-(2)-on-(1)-ilalchil-carbossilici,procedimento per la loro preparazione e prodotti medicinali che le contengono
FR2515179A1 (fr) * 1981-07-24 1983-04-29 Hoffmann La Roche Derives de pyrrolidine, leur procede de preparation, les intermediaires pour leur synthese et leur application therapeutique
IT1206699B (it) * 1984-02-27 1989-04-27 Isf Spa Procedimento per preparare derivati di pirrolidone.
IT1173768B (it) * 1984-04-02 1987-06-24 Isf Spa Procedimento di preparazione di derivati 1-carbamoilmetilici di 4-idrossi-2-osso-pirrolidina nonche' di intermedi per ottenere tali composti
CH666483A5 (de) * 1985-01-16 1988-07-29 Lonza Ag Verfahren zur herstellung von thiotetronsaeure.
IT1190378B (it) * 1985-06-21 1988-02-16 Isf Spa Derivati pirrolidonici
US4686296A (en) * 1985-07-26 1987-08-11 Denki Kagaku Kogyo Kabushiki Kaisha Process for producing oxiracetam
HU195773B (en) * 1985-09-24 1988-07-28 Lonza Ag Process for preparing alkyl esters of 4-alkoxy-3-pyrrolin-2-on-1-yl-acetic acid
CH668423A5 (de) * 1986-06-19 1988-12-30 Lonza Ag Verfahren zur herstellung von 4-alkoxy-3-pyrrolin-2-onen.
IL80071A0 (en) * 1985-09-24 1986-12-31 Lonza Ag Pyrrolidine acetamide derivatives
CH668424A5 (de) * 1986-06-26 1988-12-30 Lonza Ag 4-benzyloxy-3-pyrrolin-2-on-l-yl-acetamid, dessen herstellung und verwendung.
CH668422A5 (de) * 1986-06-26 1988-12-30 Lonza Ag 4-benzyloxy-3-pyrrolin-2-on, dessen herstellung und verwendung zur synthese von tetramsaeure.
CH667655A5 (de) * 1986-09-24 1988-10-31 Lonza Ag Verfahren zur herstellung von 4-alkoxy-2(5h)-thiophenonen.
CH670644A5 (es) * 1986-12-18 1989-06-30 Lonza Ag
DE58909320D1 (de) * 1988-09-06 1995-08-03 Lonza Ag Verfahren zur Herstellung von 5-Alkyltetramsäuren.
FI95034C (fi) * 1989-03-15 1995-12-11 Lonza Ag Menetelmä 1,3-substituoidun tetrahydro-1H-tieno/3,4-d/-imidatsol-2(3H)-on-4-ylideenipentaanihappoesterin valmistamiseksi
CH680293A5 (es) * 1990-06-26 1992-07-31 Lonza Ag
CN101704778B (zh) * 2009-09-30 2012-10-17 厦门市华兴化工有限公司 一种制备4-羟基吡咯烷酮-2-乙酰胺的方法
WO2011143872A1 (zh) * 2010-05-21 2011-11-24 重庆润泽医疗器械有限公司 一种(s)-4-羟基-2-氧代-1-吡咯烷乙酰胺晶型及其制备方法和用途
US10793521B2 (en) 2016-10-24 2020-10-06 Chongqing Ruzer Pharmaceutical Company Limited Crystalline form II of dextral oxiracetam, preparation method therefor and use thereof
KR20190053253A (ko) 2016-10-24 2019-05-17 충칭 룬즈 파마슈티컬 컴퍼니 리미티드. 덱스트랄 옥시라세탐의 새로운 결정형, 이의 제조 방법 및 이의 용도
EP3530650A4 (en) * 2016-10-24 2020-03-25 Chongqing Runze Pharmaceutical Company Limited CRYSTALLINE FORM OF (R) -4-HYDROXY-2-OXO-1-PYRROLIDINE ACETAMIDE, PRODUCTION METHOD THEREFOR, AND USE THEREOF
CN108299268A (zh) * 2017-01-12 2018-07-20 重庆润泽医药有限公司 一种(r)-4-羟基-2-氧-1-吡咯烷乙酰胺晶型的制备方法
CN108299267A (zh) * 2017-01-12 2018-07-20 重庆润泽医药有限公司 (r)-4-羟基-2-氧-1-吡咯烷乙酰胺的晶型及其制备方法和用途

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ181727A (en) 1975-08-13 1978-03-06 Isf Spa Pyrroline-2-one derivatives and pharmaceutical compositions
IT1045043B (it) 1975-08-13 1980-04-21 Isf Spa Derivati pirrolidinici

Also Published As

Publication number Publication date
CA1083585A (en) 1980-08-12
YU30378A (en) 1982-10-31
ATA88778A (de) 1980-11-15
DK155279C (da) 1989-07-24
NL7801501A (nl) 1978-08-15
SE7801537L (sv) 1978-08-12
PL108024B1 (pl) 1980-03-31
IT1075564B (it) 1985-04-22
NL187207B (nl) 1991-02-01
DE2759033A1 (de) 1978-08-17
AR219734A1 (es) 1980-09-15
SE428208B (sv) 1983-06-13
US4124594A (en) 1978-11-07
IN147764B (es) 1980-06-21
DK155279B (da) 1989-03-20
JPS53101368A (en) 1978-09-04
DE2759033C2 (de) 1984-04-19
PT67641A (de) 1978-03-01
NO147751C (no) 1983-06-08
PL204550A1 (pl) 1978-12-04
NO147751B (no) 1983-02-28
CS214767B2 (en) 1982-05-28
YU40322B (en) 1985-12-31
SU984407A3 (ru) 1982-12-23
NO780463L (no) 1978-08-14
FI66847C (fi) 1984-12-10
FI66847B (fi) 1984-08-31
PT67641B (de) 1980-03-03
HU178588B (en) 1982-05-28
JPS6338349B2 (es) 1988-07-29
DK63078A (da) 1978-08-12
AT362781B (de) 1981-06-10
GB1588074A (en) 1981-04-15
CH631703A5 (de) 1982-08-31
NL187207C (nl) 1991-07-01
MX4988E (es) 1983-01-31
FI780406A (fi) 1978-08-12

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