DK155279C - Fremgangsmaade til fremstilling af 4-hydroxy-2-oxo-pyrrolidinderivater - Google Patents
Fremgangsmaade til fremstilling af 4-hydroxy-2-oxo-pyrrolidinderivaterInfo
- Publication number
- DK155279C DK155279C DK063078A DK63078A DK155279C DK 155279 C DK155279 C DK 155279C DK 063078 A DK063078 A DK 063078A DK 63078 A DK63078 A DK 63078A DK 155279 C DK155279 C DK 155279C
- Authority
- DK
- Denmark
- Prior art keywords
- ingrediates
- pyrrolide
- oxo
- hydroxy
- preparing
- Prior art date
Links
- MNGLAWOHKCKNMT-UHFFFAOYSA-N tetramic acid Chemical compound OC1=CNC(=O)C1 MNGLAWOHKCKNMT-UHFFFAOYSA-N 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/18—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
- C07D207/22—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D207/24—Oxygen or sulfur atoms
- C07D207/26—2-Pyrrolidones
- C07D207/273—2-Pyrrolidones with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to other ring carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Neurology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Pyrrole Compounds (AREA)
- Hydrogenated Pyridines (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT2022677 | 1977-02-11 | ||
| IT20226/77A IT1075564B (it) | 1977-02-11 | 1977-02-11 | Procedimento per la preparazione di derivati pirrolidinici |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| DK63078A DK63078A (da) | 1978-08-12 |
| DK155279B DK155279B (da) | 1989-03-20 |
| DK155279C true DK155279C (da) | 1989-07-24 |
Family
ID=11164922
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK063078A DK155279C (da) | 1977-02-11 | 1978-02-10 | Fremgangsmaade til fremstilling af 4-hydroxy-2-oxo-pyrrolidinderivater |
Country Status (23)
| Country | Link |
|---|---|
| US (1) | US4124594A (cs) |
| JP (1) | JPS53101368A (cs) |
| AR (1) | AR219734A1 (cs) |
| AT (1) | AT362781B (cs) |
| CA (1) | CA1083585A (cs) |
| CH (1) | CH631703A5 (cs) |
| CS (1) | CS214767B2 (cs) |
| DE (1) | DE2759033C2 (cs) |
| DK (1) | DK155279C (cs) |
| ES (1) | ES466857A1 (cs) |
| FI (1) | FI66847C (cs) |
| GB (1) | GB1588074A (cs) |
| HU (1) | HU178588B (cs) |
| IN (1) | IN147764B (cs) |
| IT (1) | IT1075564B (cs) |
| MX (1) | MX4988E (cs) |
| NL (1) | NL187207C (cs) |
| NO (1) | NO147751C (cs) |
| PL (1) | PL108024B1 (cs) |
| PT (1) | PT67641B (cs) |
| SE (1) | SE428208B (cs) |
| SU (1) | SU984407A3 (cs) |
| YU (1) | YU40322B (cs) |
Families Citing this family (25)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2858573A (en) * | 1958-11-04 | Fibers | ||
| IT1141287B (it) * | 1979-06-13 | 1986-10-01 | Nattermann A & Cie | Ammidi di acidi pirrolidin-(2)-on-(1)-ilalchil-carbossilici,procedimento per la loro preparazione e prodotti medicinali che le contengono |
| FR2515179A1 (fr) * | 1981-07-24 | 1983-04-29 | Hoffmann La Roche | Derives de pyrrolidine, leur procede de preparation, les intermediaires pour leur synthese et leur application therapeutique |
| IT1206699B (it) * | 1984-02-27 | 1989-04-27 | Isf Spa | Procedimento per preparare derivati di pirrolidone. |
| IT1173768B (it) * | 1984-04-02 | 1987-06-24 | Isf Spa | Procedimento di preparazione di derivati 1-carbamoilmetilici di 4-idrossi-2-osso-pirrolidina nonche' di intermedi per ottenere tali composti |
| CH666483A5 (de) * | 1985-01-16 | 1988-07-29 | Lonza Ag | Verfahren zur herstellung von thiotetronsaeure. |
| IT1190378B (it) * | 1985-06-21 | 1988-02-16 | Isf Spa | Derivati pirrolidonici |
| DE3683728D1 (de) * | 1985-07-26 | 1992-03-12 | Denki Kagaku Kogyo Kk | Verfahren zur herstellung von oxiracetam. |
| CH668423A5 (de) * | 1986-06-19 | 1988-12-30 | Lonza Ag | Verfahren zur herstellung von 4-alkoxy-3-pyrrolin-2-onen. |
| HU195773B (en) * | 1985-09-24 | 1988-07-28 | Lonza Ag | Process for preparing alkyl esters of 4-alkoxy-3-pyrrolin-2-on-1-yl-acetic acid |
| IL80071A0 (en) * | 1985-09-24 | 1986-12-31 | Lonza Ag | Pyrrolidine acetamide derivatives |
| CH668422A5 (de) * | 1986-06-26 | 1988-12-30 | Lonza Ag | 4-benzyloxy-3-pyrrolin-2-on, dessen herstellung und verwendung zur synthese von tetramsaeure. |
| CH668424A5 (de) * | 1986-06-26 | 1988-12-30 | Lonza Ag | 4-benzyloxy-3-pyrrolin-2-on-l-yl-acetamid, dessen herstellung und verwendung. |
| CH667655A5 (de) * | 1986-09-24 | 1988-10-31 | Lonza Ag | Verfahren zur herstellung von 4-alkoxy-2(5h)-thiophenonen. |
| CH670644A5 (cs) * | 1986-12-18 | 1989-06-30 | Lonza Ag | |
| EP0358128B1 (de) * | 1988-09-06 | 1995-06-28 | Lonza Ag | Verfahren zur Herstellung von 5-Alkyltetramsäuren |
| FI95034C (fi) * | 1989-03-15 | 1995-12-11 | Lonza Ag | Menetelmä 1,3-substituoidun tetrahydro-1H-tieno/3,4-d/-imidatsol-2(3H)-on-4-ylideenipentaanihappoesterin valmistamiseksi |
| CH680293A5 (cs) * | 1990-06-26 | 1992-07-31 | Lonza Ag | |
| CN101704778B (zh) * | 2009-09-30 | 2012-10-17 | 厦门市华兴化工有限公司 | 一种制备4-羟基吡咯烷酮-2-乙酰胺的方法 |
| ES2587978T3 (es) * | 2010-05-21 | 2016-10-28 | Chongqing Runze Pharmaceutical Co., Ltd. | Forma cristalina de (s)-4-hidroxi-2-oxo-1-pirrolidina acetamida, método de preparación y uso de la misma |
| WO2018076783A1 (zh) | 2016-10-24 | 2018-05-03 | 重庆润泽医药有限公司 | 右旋奥拉西坦晶型ii及其制备方法和用途 |
| WO2018076784A1 (zh) * | 2016-10-24 | 2018-05-03 | 重庆润泽医药有限公司 | （r）-4-羟基-2-氧代-1-吡咯烷乙酰胺晶型及其制备方法和用途 |
| CN107973737B (zh) | 2016-10-24 | 2020-03-24 | 重庆润泽医药有限公司 | 右旋奥拉西坦新晶型及其制备方法和用途 |
| CN108299267A (zh) * | 2017-01-12 | 2018-07-20 | 重庆润泽医药有限公司 | (r)-4-羟基-2-氧-1-吡咯烷乙酰胺的晶型及其制备方法和用途 |
| CN108299268A (zh) * | 2017-01-12 | 2018-07-20 | 重庆润泽医药有限公司 | 一种(r)-4-羟基-2-氧-1-吡咯烷乙酰胺晶型的制备方法 |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IT1045043B (it) | 1975-08-13 | 1980-04-21 | Isf Spa | Derivati pirrolidinici |
| IN141326B (cs) | 1975-08-13 | 1977-02-12 | Isf Spa |
-
1977
- 1977-02-11 IT IT20226/77A patent/IT1075564B/it active Protection Beyond IP Right Term
- 1977-12-30 DE DE2759033A patent/DE2759033C2/de not_active Expired
-
1978
- 1978-02-08 US US05/876,167 patent/US4124594A/en not_active Expired - Lifetime
- 1978-02-08 FI FI780406A patent/FI66847C/fi not_active IP Right Cessation
- 1978-02-08 IN IN103/DEL/78A patent/IN147764B/en unknown
- 1978-02-08 AR AR271029A patent/AR219734A1/es active
- 1978-02-08 AT AT0088778A patent/AT362781B/de not_active IP Right Cessation
- 1978-02-08 GB GB5045/78A patent/GB1588074A/en not_active Expired
- 1978-02-08 CS CS78815A patent/CS214767B2/cs unknown
- 1978-02-09 CA CA296,522A patent/CA1083585A/en not_active Expired
- 1978-02-09 NL NLAANVRAGE7801501,A patent/NL187207C/xx not_active IP Right Cessation
- 1978-02-09 SE SE7801537A patent/SE428208B/sv not_active IP Right Cessation
- 1978-02-09 YU YU303/78A patent/YU40322B/xx unknown
- 1978-02-09 CH CH145678A patent/CH631703A5/de not_active IP Right Cessation
- 1978-02-09 PT PT67641A patent/PT67641B/pt unknown
- 1978-02-09 HU HU78IE825A patent/HU178588B/hu not_active IP Right Cessation
- 1978-02-09 MX MX786834U patent/MX4988E/es unknown
- 1978-02-10 NO NO780463A patent/NO147751C/no unknown
- 1978-02-10 DK DK063078A patent/DK155279C/da not_active IP Right Cessation
- 1978-02-10 JP JP1484578A patent/JPS53101368A/ja active Granted
- 1978-02-10 PL PL1978204550A patent/PL108024B1/pl unknown
- 1978-02-10 ES ES466857A patent/ES466857A1/es not_active Expired
- 1978-02-10 SU SU782579300A patent/SU984407A3/ru active
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PUP | Patent expired |