FI61875C - Foerfarande foer framstaellning av nya terapeutiskt anvaendbara trifluormetylfenon-0-(2-aminoetyl)-oximer - Google Patents

Foerfarande foer framstaellning av nya terapeutiskt anvaendbara trifluormetylfenon-0-(2-aminoetyl)-oximer Download PDF

Info

Publication number
FI61875C
FI61875C FI760699A FI760699A FI61875C FI 61875 C FI61875 C FI 61875C FI 760699 A FI760699 A FI 760699A FI 760699 A FI760699 A FI 760699A FI 61875 C FI61875 C FI 61875C
Authority
FI
Finland
Prior art keywords
formula
compound
aminoethyl
oxime
defined above
Prior art date
Application number
FI760699A
Other languages
English (en)
Finnish (fi)
Other versions
FI61875B (fi
FI760699A (hu
Inventor
Hendricus Bernardus Anto Welle
Volkert Claassen
Original Assignee
Duphar Int Res
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Duphar Int Res filed Critical Duphar Int Res
Publication of FI760699A publication Critical patent/FI760699A/fi
Publication of FI61875B publication Critical patent/FI61875B/fi
Application granted granted Critical
Publication of FI61875C publication Critical patent/FI61875C/fi

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C251/00Compounds containing nitrogen atoms doubly-bound to a carbon skeleton
    • C07C251/32Oximes
    • C07C251/50Oximes having oxygen atoms of oxyimino groups bound to carbon atoms of substituted hydrocarbon radicals
    • C07C251/58Oximes having oxygen atoms of oxyimino groups bound to carbon atoms of substituted hydrocarbon radicals of hydrocarbon radicals substituted by nitrogen atoms not being part of nitro or nitroso groups
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C249/00Preparation of compounds containing nitrogen atoms doubly-bound to a carbon skeleton
    • C07C249/04Preparation of compounds containing nitrogen atoms doubly-bound to a carbon skeleton of oximes
    • C07C249/08Preparation of compounds containing nitrogen atoms doubly-bound to a carbon skeleton of oximes by reaction of hydroxylamines with carbonyl compounds

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
FI760699A 1975-03-20 1976-03-17 Foerfarande foer framstaellning av nya terapeutiskt anvaendbara trifluormetylfenon-0-(2-aminoetyl)-oximer FI61875C (fi)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
NL7503310 1975-03-20
NL7503310A NL7503310A (nl) 1975-03-20 1975-03-20 Verbindingen met antidepressieve werking.

Publications (3)

Publication Number Publication Date
FI760699A FI760699A (hu) 1976-09-21
FI61875B FI61875B (fi) 1982-06-30
FI61875C true FI61875C (fi) 1982-10-11

Family

ID=19823424

Family Applications (1)

Application Number Title Priority Date Filing Date
FI760699A FI61875C (fi) 1975-03-20 1976-03-17 Foerfarande foer framstaellning av nya terapeutiskt anvaendbara trifluormetylfenon-0-(2-aminoetyl)-oximer

Country Status (27)

Country Link
US (1) US4085225A (hu)
JP (1) JPS6026776B2 (hu)
AR (2) AR211011A1 (hu)
AT (1) AT340895B (hu)
AU (1) AU505358B2 (hu)
BE (1) BE839744A (hu)
CA (1) CA1076142A (hu)
CH (4) CH626057A5 (hu)
DD (1) DD128332A5 (hu)
DE (1) DE2610886A1 (hu)
DK (1) DK144942C (hu)
ES (1) ES446192A1 (hu)
FI (1) FI61875C (hu)
FR (1) FR2304336A1 (hu)
GB (1) GB1535226A (hu)
GR (1) GR60052B (hu)
HU (1) HU171030B (hu)
IE (1) IE43768B1 (hu)
IL (1) IL49238A (hu)
IT (1) IT1063064B (hu)
MX (1) MX9203723A (hu)
NL (1) NL7503310A (hu)
PL (3) PL100052B1 (hu)
SE (1) SE410312B (hu)
SU (3) SU635867A3 (hu)
YU (1) YU39345B (hu)
ZA (1) ZA761434B (hu)

Families Citing this family (66)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1110460B (it) * 1977-03-02 1985-12-23 Ciba Geigy Ag Prodotti che favoriscono la crescita delle piante e prodotti che proteggono le piante a base di eteri di ossime e di esteri di ossime loro preparazione e loro impiego
FR2639942B1 (fr) * 1988-12-02 1991-03-29 Sanofi Sa Ethers oximes de propenone, procede pour leur preparation et compositions pharmaceutiques les contenant
US5665756A (en) * 1994-08-03 1997-09-09 Hoechst Marion Roussel, Inc. Aminoalkyloximes useful in the treatment of depression and obsessive compulsive disorders
US6548084B2 (en) * 1995-07-20 2003-04-15 Smithkline Beecham Plc Controlled release compositions
DE69607904T2 (de) * 1995-08-16 2000-10-05 Eli Lilly And Co., Indianapolis Potenzierung von Serotonin-Wirkstoffresponz
IN182588B (hu) 1998-05-12 1999-05-08 Sun Pharmaceutical Ind Ltd
IE990406A1 (en) 1999-05-20 2000-12-27 Elan Corp Plc Multiparticulate controlled release selective serotonin reuptake inhibitor formulations.
IN186677B (hu) 1999-11-12 2001-10-20 Sun Pharmaceutical Ind Ltd
AU2001257022B2 (en) * 2000-04-13 2005-02-03 Mayo Foundation For Medical Education And Research Abeta 42 lowering agents
US20080021085A1 (en) * 2000-04-13 2008-01-24 Mayo Foundation For Medical Education And Research Method of reducing abeta42 and treating diseases
CA2405025A1 (en) * 2000-04-24 2001-11-01 Aryx Therapeutics (2-aminoethyl) oxime derivatives for the treatment of depression
US7256191B2 (en) * 2000-04-24 2007-08-14 Aryx Therapeutics Materials and methods for the treatment of depression
EP1434763B1 (en) * 2001-10-12 2018-01-17 Azevan Pharmaceuticals, Inc. Beta-lactamyl vasopressin v1a antagonists
CN1649614A (zh) 2002-02-22 2005-08-03 新河药品股份有限公司 活性剂传递系统和保护及施用活性剂的方法
EP1603548A4 (en) * 2003-02-05 2007-10-10 Myriad Genetics Inc COMPOSITION AND METHOD FOR TREATING NEURODEGENERATIVE DISORDERS
KR20060040676A (ko) * 2003-07-11 2006-05-10 미리어드 제네틱스, 인크. 알츠하이머병을 치료하기 위한 약제학적 방법, 투약 방법및 제형
BRPI0414343A (pt) 2003-09-12 2006-11-07 Pfizer combinações que compreendem ligantes de alfa-2-delta e inibidores da reabsorção de serotonina/noradrenalina
ES2347152T3 (es) * 2003-11-26 2010-10-26 Pfizer Products Inc. Derivados de aminopirazol como inhibidores de gsk-3.
CA2548917C (en) 2003-12-11 2014-09-23 Sepracor Inc. Combination of a sedative and a neurotransmitter modulator, and methods for improving sleep quality and treating depression
US20070293538A1 (en) * 2004-04-13 2007-12-20 Myriad Genetics, Incorporated Pharmaceutical Composition And Methods For Treating Neurodegenerative Disorders
WO2005102366A2 (en) * 2004-04-19 2005-11-03 Philip Maxwell Satow Lithium combinations, and uses related thereto
CN1946906A (zh) * 2004-04-29 2007-04-11 吉斯通护岸系统股份有限公司 用于墙、护墙和类似物的饰面
WO2006020850A2 (en) * 2004-08-11 2006-02-23 Myriad Genetics, Inc. Pharmaceutical composition and method for treating neurodegenerative disorders
WO2006020852A2 (en) * 2004-08-11 2006-02-23 Myriad Genetics, Inc. Pharmaceutical composition and method for treating neurodegenerative disorders
WO2006020853A2 (en) * 2004-08-11 2006-02-23 Myriad Genetics, Inc. Pharmaceutical composition and method for treating neurodegenerative disorders
JP2008534504A (ja) 2005-03-22 2008-08-28 アゼヴァン ファーマスーティカルズ,インコーポレイテッド 月経前障害を治療するためのβラクタミルアルカン酸
GT200600165A (es) * 2005-04-22 2007-03-14 Derivados dihidrobenzofuranos y usos de los mismos
AR056980A1 (es) 2005-04-22 2007-11-07 Wyeth Corp Derivados de dihidrobenzofurano, composiciones farmaceuticas, y uso de los mismos
MX2007013021A (es) * 2005-04-22 2008-01-11 Wyeth Corp Derivados de benzofuranil-alcanamina y usos de los mismos como agonistas de 5-ht2c.
US20060252825A1 (en) * 2005-04-22 2006-11-09 Wyeth Crystal forms of {[(2r)-7-(2,6-dichlorophenyl)-5-fluoro-2,3-dihydro-1-benzofuran-2-yl]methyl}amine hydrochloride
CA2614289A1 (en) * 2005-07-08 2007-01-18 Braincells, Inc. Methods for identifying agents and conditions that modulate neurogenesis
US20070015832A1 (en) * 2005-07-14 2007-01-18 Myriad Genetics, Incorporated Methods of treating overactive bladder and urinary incontinence
SI1910346T1 (sl) 2005-07-19 2019-08-30 Azevan Pharmaceuticals, Inc. Antagonist beta-laktamil fenilalalina, cisteina in serin vasopresina
JP2009502807A (ja) * 2005-07-22 2009-01-29 ミリアド ジェネティクス, インコーポレイテッド 薬剤含有率の高い製剤および投与量形態
EP1940389A2 (en) 2005-10-21 2008-07-09 Braincells, Inc. Modulation of neurogenesis by pde inhibition
US20070112017A1 (en) 2005-10-31 2007-05-17 Braincells, Inc. Gaba receptor mediated modulation of neurogenesis
FR2912057B1 (fr) * 2007-02-07 2009-04-17 Sanofi Aventis Sa Composition pharmaceutique contenant en association le saredutant et un inhibiteur selectif de la recapture de la serotonine ou un inhibiteur de la recapture de la serotonine/norepinephrine
US20100216734A1 (en) 2006-03-08 2010-08-26 Braincells, Inc. Modulation of neurogenesis by nootropic agents
CA2644662A1 (en) * 2006-03-24 2007-10-04 Wyeth New therapeutic combinations for the treatment of depression
JP4615470B2 (ja) * 2006-03-29 2011-01-19 卓郎 簑和田 大脳の認知力を用いた疾患治療・予防の方法および医薬
US7858611B2 (en) * 2006-05-09 2010-12-28 Braincells Inc. Neurogenesis by modulating angiotensin
MX2008014320A (es) 2006-05-09 2009-03-25 Braincells Inc Neurogenesis mediada por el receptor de 5-hidroxitriptamina.
AU2007249399A1 (en) 2006-05-09 2007-11-22 Braincells, Inc. Neurogenesis by modulating angiotensin
WO2008006099A2 (en) * 2006-07-07 2008-01-10 Myriad Genetics, Inc. Treatment of psychiatric disorders
TW200817003A (en) * 2006-07-31 2008-04-16 Sanofi Aventis Pharmaceutical composition comprising, in combination, saredutant and a selective serotonin peuptake inhibitor or a serotonin/norepinephrine reuptake inhibitor
JP2010502722A (ja) 2006-09-08 2010-01-28 ブレインセルス,インコーポレイティド 4−アシルアミノピリジン誘導体を含む組み合わせ
US20100016274A1 (en) * 2006-09-14 2010-01-21 Koppel Gary A Beta-lactam cannabinoid receptor modulators
US20100184806A1 (en) 2006-09-19 2010-07-22 Braincells, Inc. Modulation of neurogenesis by ppar agents
WO2008083204A2 (en) * 2006-12-28 2008-07-10 Braincells, Inc. Modulation of neurogenesis by melatoninergic ligands
AU2008204800A1 (en) * 2007-01-11 2008-07-17 Braincells, Inc. Modulation of neurogenesis with use of modafinil
US20110034565A1 (en) 2008-04-18 2011-02-10 University College Dublin, National University Of Ireland, Dublin Psycho-pharmaceuticals
US20100092479A1 (en) * 2008-08-18 2010-04-15 Combinatorx (Singapore) Pte. Ltd. Compositions and methods for treatment of viral diseases
WO2010099217A1 (en) 2009-02-25 2010-09-02 Braincells, Inc. Modulation of neurogenesis using d-cycloserine combinations
MX2012004753A (es) 2009-10-23 2012-09-07 Janssen Pharmaceutica Nv Octahidropirrolo[3,4-c]pirrolos disustituidos como moduladores del receptor de orexina.
WO2011071995A2 (en) 2009-12-08 2011-06-16 Case Western Reserve University Compounds and methods of treating ocular disorders
US9376424B2 (en) 2010-07-01 2016-06-28 Azevan Pharmaceuticals, Inc. Methods for treating post traumatic stress disorder
KR20140045925A (ko) 2011-03-17 2014-04-17 루핀 리미티드 선택적 세로토닌 재흡수 억제제의 방출조절형 약제학적 조성물
KR101427221B1 (ko) * 2012-08-29 2014-08-13 주식회사 에스텍파마 플루복사민 자유 염기의 정제방법 및 이를 이용한 고순도 플루복사민 말레이트의 제조방법
PT2981518T (pt) * 2013-04-03 2021-06-04 Zcl Chemicals Ltd Um processo melhorado para a preparação de maleato de fluvoxamina
CA2938928C (en) 2014-02-07 2023-01-24 Mta Tamogatott Kutatocsoportok Irodaja Use of sigma-1 receptor agonist compounds
US9802925B2 (en) 2014-03-28 2017-10-31 Azevan Pharmaceuticals, Inc. Compositions and methods for treating neurodegenerative diseases
HUE058759T2 (hu) 2016-03-10 2022-09-28 Janssen Pharmaceutica Nv Módszerek depresszió kezelésére orexin-2 receptor antagonisták alkalmazásával
DK3544420T3 (da) 2016-11-24 2022-09-05 Sigmadrugs Kutato Korlatolt Feleloessegue Tarsasag Anvendelse af sammensætninger til organ-/vævskonservering
AU2018333051B2 (en) 2017-09-15 2024-03-21 Azevan Pharmaceuticals, Inc. Compositions and methods for treating brain injury
MX2022000709A (es) 2019-07-19 2022-05-19 Bioxcel Therapeutics Inc Regimenes de tratamiento con dexmedetomidina no sedante.
US11806334B1 (en) 2023-01-12 2023-11-07 Bioxcel Therapeutics, Inc. Non-sedating dexmedetomidine treatment regimens

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3692835A (en) * 1967-04-05 1972-09-19 Jan Van Dijk Pharmacologically active amino-ethyl oximes

Also Published As

Publication number Publication date
YU71476A (en) 1982-10-31
US4085225A (en) 1978-04-18
PL100052B1 (pl) 1978-08-31
NL7503310A (nl) 1976-09-22
SE410312B (sv) 1979-10-08
JPS51125345A (en) 1976-11-01
SU620206A3 (ru) 1978-08-15
AU505358B2 (en) 1979-11-15
CA1076142A (en) 1980-04-22
MX9203723A (es) 1992-07-01
AT340895B (de) 1978-01-10
YU39345B (en) 1984-10-31
FR2304336B1 (hu) 1979-09-28
DE2610886C2 (hu) 1987-09-24
DE2610886A1 (de) 1976-10-07
ES446192A1 (es) 1977-10-01
BE839744A (fr) 1976-09-20
IL49238A (en) 1978-08-31
IL49238A0 (en) 1976-05-31
AR211153A1 (es) 1977-10-31
ATA195476A (de) 1977-05-15
DD128332A5 (de) 1977-11-09
FI61875B (fi) 1982-06-30
DK144942B (da) 1982-07-12
SE7603341L (sv) 1976-09-21
IE43768B1 (en) 1981-05-20
FI760699A (hu) 1976-09-21
AR211011A1 (es) 1977-10-14
AU1214776A (en) 1977-09-22
IT1063064B (it) 1985-02-11
CH626057A5 (hu) 1981-10-30
SU645559A3 (ru) 1979-01-30
CH629477A5 (de) 1982-04-30
CH629184A5 (de) 1982-04-15
GB1535226A (en) 1978-12-13
GR60052B (en) 1978-04-04
DK115976A (da) 1976-09-21
PL101951B1 (pl) 1979-02-28
HU171030B (hu) 1977-10-28
ZA761434B (en) 1977-10-26
CH629761A5 (de) 1982-05-14
JPS6026776B2 (ja) 1985-06-25
SU635867A3 (ru) 1978-11-30
FR2304336A1 (fr) 1976-10-15
DK144942C (da) 1982-12-06
PL100614B1 (pl) 1978-10-31
IE43768L (en) 1976-09-20

Similar Documents

Publication Publication Date Title
FI61875C (fi) Foerfarande foer framstaellning av nya terapeutiskt anvaendbara trifluormetylfenon-0-(2-aminoetyl)-oximer
PL150887B1 (en) Method of diphenylprophylamine new derivatives manufacture
PL149288B1 (en) Method of obtaining novel n-/2-(4-fluorophenyl)-1-methyl/-ethyl-n-methyl-n-propynylamine
SU841587A3 (ru) Способ получени производныхАлКилЕНдиАМиНА или иХ КиСлОТНО-АддиТиВНыХ СОлЕй
US4575508A (en) 2-Substituted 1-(3'-aminoalkyl)-1,2,3,4-tetrahydro-β-carbolines, and their use as antiarrhythmic agents
SU1223843A3 (ru) Способ получени 1-фенил-2-аминокарбонилиндольных соединений или их кислотно-аддитивных солей
US3944566A (en) Tricyclic substituted aminoalcohols
TWI236469B (en) Diamine compound with condensed-ring groups
NO312243B1 (no) N-substituerte 3-azabicyklo[3.2.0]heptanderivater egnet som neuroleptika
FI62063B (fi) Foerfarande foer framstaellning av nya terapeutiskt anvaendbara 4-klor eller brom-fenon-0-(2-aminoetyl)-oximer
FI97131C (fi) Menetelmä terapeuttisesti aktiivisten piperidiinijohdannaisten valmistamiseksi
SU955860A3 (ru) Способ получени производных 3-амино-1-бензоксепин-5/2н/-она или их солей
FI62288C (fi) Foerfarande foer framstaellning av nya terapeutiskt anvaendbara 4-metyltiofenon-0-(2-aminoetyl)-oximer
PL163028B1 (pl) Sposób wytwarzania nowych pochodnych aminopropanolu PL PL PL
FI62062C (fi) Foerfarande foer framstaellning av terapeutiskt anvaendbara 3,-diklorfenon-0-(2-aminoetyl)-oximer
FI78081B (fi) Foerfarande foer framstaellning av terapeutiskt anvaendbara 2-(n-pyrrolidino)-3-isobutoxi-n- (substituerad-fenyl)-n-bensylpropylaminer.
DK152491B (da) Analogifremgangsmaade til fremstilling af esterholdige phenoxypropanolaminer eller farmaceutisk anvendelige salte deraf
HU181736B (en) Process for producing new 3-amino-1-benzoxepine derivatives
FI61874C (fi) Analogifoerfarande foer framstaellning av nya saosom antidepressivt verkande mediciner anvaendbara metylsulfinylfenon-0-(2-aminoetyl)-oximer och salter daerav
US4060613A (en) 3-Aryloxy-2(4-loweralkyl-1-piperazinyl)propanols, their alkylethers, and use thereof
US5523303A (en) Trisubstituted cycloalkane derivatives and process for the preparation thereof
FI61876C (fi) Foerfarande foer framstaellning av terapeutiskt anvaendbara 1,a,6,10b-tetrahydrodibenso(a,e)cyklopropa(c)cyklohepten-6- onximderivat
JP2002529533A (ja) 尿失禁治療用1−アミノエチルキノリン誘導体
JPH04505926A (ja) ムスカリン受容体アンタゴニスト
US4008331A (en) Antidepressant 1,1a,6,10b-tetrahydrodibenzo-[a,e]-cyclopropa-[c]-cyclohepten-6-substituted oximes

Legal Events

Date Code Title Description
MA Patent expired
MA Patent expired

Owner name: DUPHAR INTERNATIONAL RESEARCH B.V