FI3429571T3 - Lsd1-inhibiittorien yhdistelmiä käytettäväksi kasvaintautien hoitamisessa - Google Patents

Lsd1-inhibiittorien yhdistelmiä käytettäväksi kasvaintautien hoitamisessa

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Publication number
FI3429571T3
FI3429571T3 FIEP17710261.3T FI17710261T FI3429571T3 FI 3429571 T3 FI3429571 T3 FI 3429571T3 FI 17710261 T FI17710261 T FI 17710261T FI 3429571 T3 FI3429571 T3 FI 3429571T3
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FI
Finland
Prior art keywords
pharmaceutically acceptable
acceptable salt
cancer
use according
therapeutic combination
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Application number
FIEP17710261.3T
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English (en)
Finnish (fi)
Inventor
Mark Demario
William Pierceall
Fiona Mack
Tamara Maes
Serena Lunardi
Original Assignee
Oryzon Genomics S A
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Application filed by Oryzon Genomics S A filed Critical Oryzon Genomics S A
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Publication of FI3429571T3 publication Critical patent/FI3429571T3/fi

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/12Ketones
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/13Amines
    • A61K31/135Amines having aromatic rings, e.g. ketamine, nortriptyline
    • AHUMAN NECESSITIES
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    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/16Amides, e.g. hydroxamic acids
    • A61K31/165Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • A61K31/167Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide having the nitrogen of a carboxamide group directly attached to the aromatic ring, e.g. lidocaine, paracetamol
    • AHUMAN NECESSITIES
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    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19Carboxylic acids, e.g. valproic acid
    • AHUMAN NECESSITIES
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    • A61K31/28Compounds containing heavy metals
    • A61K31/282Platinum compounds
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    • A61K31/335Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/337Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having four-membered rings, e.g. taxol
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    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/403Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
    • A61K31/404Indoles, e.g. pindolol
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  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
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  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
FIEP17710261.3T 2016-03-15 2017-03-13 Lsd1-inhibiittorien yhdistelmiä käytettäväksi kasvaintautien hoitamisessa FI3429571T3 (fi)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201662308529P 2016-03-15 2016-03-15
PCT/EP2017/055784 WO2017157825A1 (en) 2016-03-15 2017-03-13 Combinations of lsd1 inhibitors for use in the treatment of solid tumors

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FI3429571T3 true FI3429571T3 (fi) 2026-01-12

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