SG10201913331VA - Combinations of lsd1 inhibitors for use in the treatment of solid tumors - Google Patents

Combinations of lsd1 inhibitors for use in the treatment of solid tumors

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Publication number
SG10201913331VA
SG10201913331VA SG10201913331VA SG10201913331VA SG10201913331VA SG 10201913331V A SG10201913331V A SG 10201913331VA SG 10201913331V A SG10201913331V A SG 10201913331VA SG 10201913331V A SG10201913331V A SG 10201913331VA SG 10201913331V A SG10201913331V A SG 10201913331VA
Authority
SG
Singapore
Prior art keywords
combinations
treatment
solid tumors
lsd1 inhibitors
lsd1
Prior art date
Application number
SG10201913331VA
Other languages
English (en)
Inventor
Mark Demario
William Pierceall
Fiona Mack
Tamara Maes
Serena Lunardi
Original Assignee
Oryzon Genomics Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Oryzon Genomics Sa filed Critical Oryzon Genomics Sa
Publication of SG10201913331VA publication Critical patent/SG10201913331VA/en

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    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
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    • A61K31/16—Amides, e.g. hydroxamic acids
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    • A61K31/167—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide having the nitrogen of a carboxamide group directly attached to the aromatic ring, e.g. lidocaine, paracetamol
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  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
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SG10201913331VA 2016-03-15 2017-03-13 Combinations of lsd1 inhibitors for use in the treatment of solid tumors SG10201913331VA (en)

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EP (1) EP3429571B1 (enExample)
JP (2) JP7158023B2 (enExample)
KR (2) KR20230042756A (enExample)
CN (2) CN109195593A (enExample)
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CN104203914B (zh) 2011-10-20 2017-07-11 奥瑞泽恩基因组学股份有限公司 作为lsd1抑制剂的(杂)芳基环丙胺化合物
EP3090998A1 (en) 2015-05-06 2016-11-09 F. Hoffmann-La Roche AG Solid forms
KR102511028B1 (ko) * 2016-03-15 2023-03-16 오리존 지노믹스 에스.에이. 혈액 악성 종양의 치료를 위한 lsd1 억제제의 조합물
SG11201807965YA (en) 2016-03-15 2018-10-30 Oryzon Genomics Sa Combinations of lsd1 inhibitors for use in the treatment of solid tumors
US10780081B2 (en) 2016-06-10 2020-09-22 Oryzon Genomics, S.A. Method of treating multiple sclerosis employing a LSD1-inhibitor
WO2019083971A1 (en) 2017-10-23 2019-05-02 Children's Medical Center Corporation METHODS OF TREATING CANCER USING LSD1 INHIBITORS IN COMBINATION WITH IMMUNOTHERAPY
AU2018359907A1 (en) 2017-11-06 2020-05-07 Fred Hutchinson Cancer Center Combination of a cell therapy and a gamma secretase inhibitor
US11597933B2 (en) 2017-11-29 2023-03-07 The Trustees Of Columbia University In The City Of New York Combination therapy of lymphoma
WO2019211491A1 (en) * 2018-05-04 2019-11-07 Oryzon Genomics, S.A. Stable pharmaceutical formulation
JP7522661B2 (ja) 2018-05-06 2024-07-25 アヤラ ファーマシューティカルズ インコーポレイテッド ビスフルオロアルキル－１，４－ベンゾジアゼピノン化合物を含む組み合わせ組成物およびその使用方法
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