MY199967A - Combinations of lsd1 inhibitors for use in the treatment of solid tumors - Google Patents

Combinations of lsd1 inhibitors for use in the treatment of solid tumors

Info

Publication number
MY199967A
MY199967A MYPI2018001572A MYPI2018001572A MY199967A MY 199967 A MY199967 A MY 199967A MY PI2018001572 A MYPI2018001572 A MY PI2018001572A MY PI2018001572 A MYPI2018001572 A MY PI2018001572A MY 199967 A MY199967 A MY 199967A
Authority
MY
Malaysia
Prior art keywords
combinations
treatment
lsd1 inhibitors
solid tumors
cancer
Prior art date
Application number
MYPI2018001572A
Other languages
English (en)
Inventor
Serena Lunardi
Tamara Maes
Mark Demario
William Pierceall
Fiona Mack
Original Assignee
Oryzon Genomics Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Oryzon Genomics Sa filed Critical Oryzon Genomics Sa
Publication of MY199967A publication Critical patent/MY199967A/en

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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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    • A61K31/12—Ketones
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    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
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    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • A61K31/167—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide having the nitrogen of a carboxamide group directly attached to the aromatic ring, e.g. lidocaine, paracetamol
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    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Molecular Biology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pain & Pain Management (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Oncology (AREA)
  • Hematology (AREA)
  • Pulmonology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Inorganic Chemistry (AREA)
MYPI2018001572A 2016-03-15 2017-03-13 Combinations of lsd1 inhibitors for use in the treatment of solid tumors MY199967A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201662308529P 2016-03-15 2016-03-15
PCT/EP2017/055784 WO2017157825A1 (en) 2016-03-15 2017-03-13 Combinations of lsd1 inhibitors for use in the treatment of solid tumors

Publications (1)

Publication Number Publication Date
MY199967A true MY199967A (en) 2023-11-30

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Application Number Title Priority Date Filing Date
MYPI2018001572A MY199967A (en) 2016-03-15 2017-03-13 Combinations of lsd1 inhibitors for use in the treatment of solid tumors

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US (2) US10265279B2 (enExample)
EP (1) EP3429571B1 (enExample)
JP (2) JP7158023B2 (enExample)
KR (2) KR102511024B1 (enExample)
CN (2) CN120661674A (enExample)
AR (1) AR107871A1 (enExample)
AU (2) AU2017233898B2 (enExample)
CA (1) CA3017411C (enExample)
EA (1) EA201892075A1 (enExample)
IL (1) IL261721B (enExample)
MX (2) MX381890B (enExample)
MY (1) MY199967A (enExample)
SG (2) SG10201913331VA (enExample)
WO (1) WO2017157825A1 (enExample)

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EP3090998A1 (en) 2015-05-06 2016-11-09 F. Hoffmann-La Roche AG Solid forms
EP3307267B1 (en) 2016-06-10 2019-04-10 Oryzon Genomics, S.A. Multiple sclerosis treatment
AU2017233898B2 (en) 2016-03-15 2022-12-15 Oryzon Genomics, S.A. Combinations of LSD1 inhibitors for use in the treatment of solid tumors
KR102646126B1 (ko) * 2016-03-15 2024-03-11 오리존 지노믹스 에스.에이. 혈액 악성 종양의 치료를 위한 lsd1 억제제의 조합물
US11685782B2 (en) 2017-10-23 2023-06-27 Children's Medical Center Corporation Methods of treating cancer using LSD1 inhibitors in combination with immunotherapy
MA50564A (fr) 2017-11-06 2020-09-16 Hutchinson Fred Cancer Res Association d'une thérapie cellulaire et d'un inhibiteur de gamma secrétase
WO2019108789A1 (en) * 2017-11-29 2019-06-06 The Trustees Of Columbia University In The City Of New York Combination therapy of lymphoma
KR20210006426A (ko) * 2018-05-04 2021-01-18 오리존 지노믹스 에스.에이. 안정한 약제학적 제제
MX2020011826A (es) 2018-05-06 2021-01-15 Ayala Pharmaceuticals Inc Composiciones de combinacion que comprenden compuestos de bisfluoroalquil-1,4-benzodiazepinona y metodos de uso de las mismas.
CN109265462B (zh) * 2018-10-31 2020-06-02 郑州大学 嘧啶并1,2,4-三氮唑类化合物及其制备方法和应用
SG11202109025XA (en) * 2019-03-25 2021-09-29 Oryzon Genomics Sa Combinations of iadademstat for cancer therapy
JP2022546908A (ja) * 2019-07-05 2022-11-10 オリゾン・ゲノミクス・ソシエダッド・アノニマ Ｋｄｍ１ａ阻害剤を使用した小細胞肺がんの個別化された処置のためのバイオマーカーおよび方法
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