FI118792B - Käyttöjä T-solutoleranssin indusoinniksi kudos- tai elinsiirrännäiselle - Google Patents
Käyttöjä T-solutoleranssin indusoinniksi kudos- tai elinsiirrännäiselle Download PDFInfo
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- FI118792B FI118792B FI964272A FI964272A FI118792B FI 118792 B FI118792 B FI 118792B FI 964272 A FI964272 A FI 964272A FI 964272 A FI964272 A FI 964272A FI 118792 B FI118792 B FI 118792B
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- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
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- C07K16/2875—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the NGF/TNF superfamily, e.g. CD70, CD95L, CD153, CD154
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- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/73—Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US08/234,987 US5683693A (en) | 1994-04-25 | 1994-04-25 | Method for inducing T cell unresponsiveness to a tissue or organ graft with anti-CD40 ligand antibody or soluble CD40 |
| US23498794 | 1994-04-25 | ||
| US9504832 | 1995-04-25 | ||
| PCT/US1995/004832 WO1995028957A2 (fr) | 1994-04-25 | 1995-04-25 | Procedes servant a provoquer la tolerance des lymphocytes t a une greffe de tissu ou d'organe |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| FI964272A0 FI964272A0 (fi) | 1996-10-23 |
| FI964272A FI964272A (fi) | 1996-12-19 |
| FI118792B true FI118792B (fi) | 2008-03-31 |
Family
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| FI964272A FI118792B (fi) | 1994-04-25 | 1996-10-23 | Käyttöjä T-solutoleranssin indusoinniksi kudos- tai elinsiirrännäiselle |
Country Status (34)
| Country | Link |
|---|---|
| US (4) | US5683693A (fr) |
| EP (2) | EP0757557B1 (fr) |
| JP (1) | JP2974415B2 (fr) |
| KR (1) | KR100468330B1 (fr) |
| CN (1) | CN1134266C (fr) |
| AP (1) | AP764A (fr) |
| AT (1) | ATE288281T1 (fr) |
| AU (1) | AU710925B2 (fr) |
| BG (1) | BG62121B1 (fr) |
| BR (1) | BR9507509A (fr) |
| CA (1) | CA2188672A1 (fr) |
| CZ (1) | CZ291266B6 (fr) |
| DE (1) | DE69533984T2 (fr) |
| DK (1) | DK0757557T3 (fr) |
| EE (1) | EE03516B1 (fr) |
| ES (1) | ES2237757T3 (fr) |
| FI (1) | FI118792B (fr) |
| GE (1) | GEP20022648B (fr) |
| HU (1) | HU221752B1 (fr) |
| IS (1) | IS2118B (fr) |
| LT (1) | LT4309B (fr) |
| LV (1) | LV11785B (fr) |
| MD (1) | MD1444B2 (fr) |
| NO (2) | NO319787B1 (fr) |
| NZ (1) | NZ284905A (fr) |
| OA (1) | OA10591A (fr) |
| PL (1) | PL180031B1 (fr) |
| PT (1) | PT757557E (fr) |
| RO (1) | RO114743B1 (fr) |
| RU (1) | RU2169009C2 (fr) |
| SI (1) | SI9520057A (fr) |
| SK (1) | SK136996A3 (fr) |
| UA (1) | UA44892C2 (fr) |
| WO (1) | WO1995028957A2 (fr) |
Families Citing this family (41)
| Publication number | Priority date | Publication date | Assignee | Title |
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| US5474771A (en) | 1991-11-15 | 1995-12-12 | The Trustees Of Columbia University In The City Of New York | Murine monoclonal antibody (5c8) recognizes a human glycoprotein on the surface of T-lymphocytes, compositions containing same |
| US7070777B1 (en) | 1991-11-15 | 2006-07-04 | The Trustees Of Columbia University In The City Of New York | Method for inhibiting inflammation with an antibody that binds the 5C8 protein |
| US6472510B1 (en) | 1992-02-14 | 2002-10-29 | Bristol-Myers Squibb Company | CD40 receptor ligands |
| NZ273207A (en) * | 1993-09-02 | 1997-09-22 | Dartmouth College | Igg antibodies gp39 (cd40) |
| KR100398819B1 (ko) * | 1993-09-02 | 2004-02-05 | 트러스티스 오브 다트마우스 칼리지 | gp39길항제를포함하는약제조성물 |
| US5683693A (en) | 1994-04-25 | 1997-11-04 | Trustees Of Dartmouth College | Method for inducing T cell unresponsiveness to a tissue or organ graft with anti-CD40 ligand antibody or soluble CD40 |
| US5876950A (en) * | 1995-01-26 | 1999-03-02 | Bristol-Myers Squibb Company | Monoclonal antibodies specific for different epitopes of human GP39 and methods for their use in diagnosis and therapy |
| US6001358A (en) * | 1995-11-07 | 1999-12-14 | Idec Pharmaceuticals Corporation | Humanized antibodies to human gp39, compositions containing thereof |
| US6440418B1 (en) * | 1995-11-07 | 2002-08-27 | Idec Pharmaceuticals Corporation | Methods of treating autoimmune diseases with gp39-specific antibodies |
| US6340459B1 (en) | 1995-12-01 | 2002-01-22 | The Trustees Of Columbia University In The City Of New York | Therapeutic applications for the anti-T-BAM (CD40-L) monoclonal antibody 5C8 in the treatment of reperfusion injury in non-transplant recipients |
| WO1997034633A1 (fr) * | 1996-03-20 | 1997-09-25 | Bristol-Myers Squibb Company | Procedes d'inhibition d'une reponse immune par blocage des voies de gp39/cd40 et ctla4/cd28/b7 et compositions utilisees avec ceux-ci |
| NZ337073A (en) * | 1997-01-10 | 2001-01-26 | Biogen Inc | use of an anti CD40L compound to treat a patient with an autoimmune disease or chronic immune system disorder |
| EP1754490A3 (fr) * | 1997-06-20 | 2010-01-20 | Biogen Idec MA Inc. | Thérapie de blocage par CD154 pour transplantation de tissus d'ilots pancréatiques chez les primates |
| HUP0003160A3 (en) * | 1997-06-20 | 2002-09-30 | Biogen Idec Ma Inc Cambridge | The use of cd40:cd154-binding inhibiting agent for the preparation of pharmaceuticals used for enhancing of tolerance against tissue graft after pangreatic islet tissue transplantation |
| US20050031611A1 (en) * | 1998-05-08 | 2005-02-10 | Beth Israel Deaconess Medical Center | Transplant tolerance by costimulation blockade and T-cell activation-induced apoptosis |
| KR100711210B1 (ko) * | 1998-07-30 | 2007-04-24 | 리젼츠 오브 더 유니버시티 오브 미네소타 | ｇｐ３９ 길항제를 사용한 동종 또는 이종 Ｔ-세포의 생체외 처리 |
| US20020199218A1 (en) * | 1999-08-19 | 2002-12-26 | Daphne Goring | Proline-rich extensin-like receptor kinases |
| RU2162297C1 (ru) * | 1999-11-25 | 2001-01-27 | Камакин Владислав Владимирович | Способ индивидуального подбора оптимального питания человека |
| WO2001079555A2 (fr) | 2000-04-14 | 2001-10-25 | Millennium Pharmaceuticals, Inc. | Roles des membres de la famille jak/stat dans l'induction de la tolerance |
| CN1441675A (zh) | 2000-05-12 | 2003-09-10 | 贝斯以色列护理医疗中心有限公司 | 免疫抑制组合物及方法 |
| EP1289554A4 (fr) * | 2000-06-02 | 2004-05-26 | Univ Minnesota | Procede immunotherapeutique permettant de prevenir le rejet de cellules insulaires |
| EP1299542A2 (fr) * | 2000-06-06 | 2003-04-09 | Idec Pharmaceuticals Corporation | Anticorps non agonistiques diriges contre gp 39 humaine, compositions les contenant et leur utilisation therapeutique |
| US20040022787A1 (en) | 2000-07-03 | 2004-02-05 | Robert Cohen | Methods for treating an autoimmune disease using a soluble CTLA4 molecule and a DMARD or NSAID |
| AU2001273174B2 (en) | 2000-07-03 | 2006-05-18 | Bristol-Myers Squibb Company | Methods for treating rheumatic diseases using a soluble CTLA4 molecule |
| CA2364983A1 (fr) * | 2000-12-13 | 2002-06-13 | John R. Coleman | Molecules d'acide nucleique et polypeptides pour le catabolisme de l'acide abscisique |
| WO2002078743A1 (fr) * | 2001-02-16 | 2002-10-10 | University Of Rochester | Compositions et techniques permettant de reduire les reactions aux transfusions |
| US7597895B2 (en) * | 2001-02-20 | 2009-10-06 | The Governing Council Of The University Of Toronto | Signal peptides, nucleic acid molecules and methods for treatment of caries |
| US7556807B2 (en) | 2001-02-20 | 2009-07-07 | Kane Biotech, Inc. | Signal peptides, nucleic acid molecules and methods for treatment of caries |
| AU2002305716B2 (en) | 2001-05-23 | 2007-10-25 | Bristol-Myers Squibb Company | Methods for protecting allogeneic islet transplant using soluble CTLA4 mutant molecules |
| US7498171B2 (en) | 2002-04-12 | 2009-03-03 | Anthrogenesis Corporation | Modulation of stem and progenitor cell differentiation, assays, and uses thereof |
| PT1517921E (pt) * | 2002-06-28 | 2006-09-29 | Domantis Ltd | Ligandos duplamente especificos com semi-vida no soro aumentada |
| CA2542984A1 (fr) * | 2003-07-07 | 2005-01-27 | David H. Wagner | Methodes de prediction du developpement de maladies auto-immunes et traitement associe |
| US7563443B2 (en) | 2004-09-17 | 2009-07-21 | Domantis Limited | Monovalent anti-CD40L antibody polypeptides and compositions thereof |
| EP1795587A1 (fr) * | 2005-12-07 | 2007-06-13 | Schuler, Gerold, Prof. Dr. | Procédés directs pour la culture de cellules dendritiques sans étape de centrifugation |
| RU2445975C2 (ru) * | 2006-03-02 | 2012-03-27 | Алексион Фармасьютикалз, Инк. | Продление срока выживаемости аллотрансплантата путем ингибирования активности комплемента |
| FR2934140B1 (fr) * | 2008-07-25 | 2010-09-03 | Seb Sa | Couvercle d'appareil electromenager de cuisson comportant un sous-ensemble de filtration |
| MX2012000086A (es) | 2009-06-26 | 2012-06-12 | Soricimed Biopharma Inc | Peptidos derivados de soricidi y metodos para la la deteccion de canceres trpv-6 y suministro de farmaco. |
| WO2013013708A1 (fr) | 2011-07-26 | 2013-01-31 | Fundació Institut D'investigació Biomèdica De Bellvitge | Traitement du rejet aigu dans une transplantation rénale |
| US9888673B2 (en) | 2014-12-10 | 2018-02-13 | Regents Of The University Of Minnesota | Genetically modified cells, tissues, and organs for treating disease |
| RU2580640C1 (ru) * | 2014-12-25 | 2016-04-10 | Федеральное государственное бюджетное учреждение "Федеральный научный центр трансплантологии и искусственных органов имени академика В.И. Шумакова" Министерства здравоохранения Российской Федерации | Способ профилактики гуморального отторжения при аво-несовместимой трансплантации печени детям раннего возраста |
| RU2688172C1 (ru) * | 2018-04-05 | 2019-05-20 | Государственное бюджетное учреждение здравоохранения Московской области "Московский областной научно-исследовательский клинический институт им. М.Ф. Владимирского" (ГБУЗ МО МОНИКИ им. М.Ф. Владимирского) | Способ профилактики отторжения трансплантата трупной почки |
Family Cites Families (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0408859B1 (fr) * | 1989-05-23 | 1995-08-09 | Otsuka Pharmaceutical Co., Ltd. | Anticorps monoclonaux contre cellules endothéliales activées |
| US5690933A (en) * | 1989-05-31 | 1997-11-25 | Glaxo Wellcome Inc. | Monoclonal antibodies for inducing tolerance |
| ATE239790T1 (de) * | 1991-10-25 | 2003-05-15 | Immunex Corp | Antikörper gegen cd40-l |
| US5474771A (en) * | 1991-11-15 | 1995-12-12 | The Trustees Of Columbia University In The City Of New York | Murine monoclonal antibody (5c8) recognizes a human glycoprotein on the surface of T-lymphocytes, compositions containing same |
| CA2089229C (fr) * | 1992-02-14 | 2010-04-13 | Alejandro A. Aruffo | Recepteur cd40cr et ligands pour celui-ci |
| AU5098493A (en) * | 1992-08-21 | 1994-03-15 | Schering Corporation | Cd40 ligand, anti cd40 antibodies, and soluble cd40 |
| US5540926A (en) * | 1992-09-04 | 1996-07-30 | Bristol-Myers Squibb Company | Soluble and its use in B cell stimulation |
| US5597563A (en) * | 1992-09-04 | 1997-01-28 | Beschorner; William E. | Method induction of antigen-specific immune tolerance |
| FI934751A (fi) * | 1992-10-30 | 1994-05-01 | Bristol Myers Squibb Co | Extracellulaera matrisreceptorligander som modulerar leukocytfunktioner |
| KR100398819B1 (ko) * | 1993-09-02 | 2004-02-05 | 트러스티스 오브 다트마우스 칼리지 | gp39길항제를포함하는약제조성물 |
| NZ273207A (en) * | 1993-09-02 | 1997-09-22 | Dartmouth College | Igg antibodies gp39 (cd40) |
| US5869049A (en) * | 1993-09-02 | 1999-02-09 | Trustees Of Dartmouth College | Methods of inducing T cell unresponsiveness to bone marrow with gp39 antagonists |
| US5683693A (en) * | 1994-04-25 | 1997-11-04 | Trustees Of Dartmouth College | Method for inducing T cell unresponsiveness to a tissue or organ graft with anti-CD40 ligand antibody or soluble CD40 |
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1994
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1995
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- 1995-04-25 RO RO96-02051A patent/RO114743B1/ro unknown
- 1995-04-25 WO PCT/US1995/004832 patent/WO1995028957A2/fr active IP Right Grant
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- 1995-04-25 CN CNB951935623A patent/CN1134266C/zh not_active Expired - Fee Related
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- 1995-04-25 CA CA002188672A patent/CA2188672A1/fr not_active Abandoned
- 1995-04-25 RU RU96122475/14A patent/RU2169009C2/ru not_active IP Right Cessation
- 1995-04-25 PL PL95317022A patent/PL180031B1/pl unknown
- 1995-04-25 KR KR1019960705968A patent/KR100468330B1/ko not_active IP Right Cessation
- 1995-04-25 EE EE9600162A patent/EE03516B1/xx not_active IP Right Cessation
- 1995-04-25 AP APAP/P/1996/000906A patent/AP764A/en active
- 1995-04-25 SK SK1369-96A patent/SK136996A3/sk unknown
- 1995-04-25 DK DK95917593T patent/DK0757557T3/da active
- 1995-04-25 AU AU23585/95A patent/AU710925B2/en not_active Ceased
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- 1995-04-25 DE DE69533984T patent/DE69533984T2/de not_active Expired - Fee Related
- 1995-04-25 HU HU9602924A patent/HU221752B1/hu not_active IP Right Cessation
- 1995-04-25 NZ NZ284905A patent/NZ284905A/en not_active IP Right Cessation
- 1995-04-25 EP EP05075209A patent/EP1530973A3/fr not_active Withdrawn
- 1995-04-25 BR BR9507509A patent/BR9507509A/pt not_active Application Discontinuation
- 1995-04-25 MD MD97-0009A patent/MD1444B2/ro unknown
- 1995-04-25 ES ES95917593T patent/ES2237757T3/es not_active Expired - Lifetime
- 1995-04-25 UA UA96114392A patent/UA44892C2/uk unknown
- 1995-04-25 CZ CZ19963125A patent/CZ291266B6/cs unknown
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1996
- 1996-10-18 NO NO19964440A patent/NO319787B1/no unknown
- 1996-10-22 IS IS4378A patent/IS2118B/is unknown
- 1996-10-23 FI FI964272A patent/FI118792B/fi active
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- 1996-11-25 LT LT96-165A patent/LT4309B/lt not_active IP Right Cessation
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1997
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1999
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2004
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