LT4309B - Receptoriaus antagonisto panaudojimas t-ląstelių tolerancijai sukelti audinių arba organų transplantacijoje - Google Patents

Receptoriaus antagonisto panaudojimas t-ląstelių tolerancijai sukelti audinių arba organų transplantacijoje Download PDF

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Publication number
LT4309B
LT4309B LT96-165A LT96165A LT4309B LT 4309 B LT4309 B LT 4309B LT 96165 A LT96165 A LT 96165A LT 4309 B LT4309 B LT 4309B
Authority
LT
Lithuania
Prior art keywords
cell
cells
antibody
tissue
allogeneic
Prior art date
Application number
LT96-165A
Other languages
English (en)
Lithuanian (lt)
Other versions
LT96165A (en
Inventor
Randolph J. Noelle
Fiona H. Durie
David C. Parker
Michael C. Appel
E. Nancy Philips
John P. Mordes
Dale L. Grenier
Aldo A. Rossini
Original Assignee
Trustees Of Dartmouth College
University Of Massachusetts Medical Center
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Trustees Of Dartmouth College, University Of Massachusetts Medical Center filed Critical Trustees Of Dartmouth College
Publication of LT96165A publication Critical patent/LT96165A/xx
Publication of LT4309B publication Critical patent/LT4309B/lt

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/0005Vertebrate antigens
    • A61K39/001Preparations to induce tolerance to non-self, e.g. prior to transplantation
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/14Blood; Artificial blood
    • A61K35/17Lymphocytes; B-cells; T-cells; Natural killer cells; Interferon-activated or cytokine-activated lymphocytes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/37Digestive system
    • A61K35/39Pancreas; Islets of Langerhans
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/46Cellular immunotherapy
    • A61K39/461Cellular immunotherapy characterised by the cell type used
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/46Cellular immunotherapy
    • A61K39/462Cellular immunotherapy characterized by the effect or the function of the cells
    • A61K39/4621Cellular immunotherapy characterized by the effect or the function of the cells immunosuppressive or immunotolerising
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/46Cellular immunotherapy
    • A61K39/464Cellular immunotherapy characterised by the antigen targeted or presented
    • A61K39/4643Vertebrate antigens
    • A61K39/46433Antigens related to auto-immune diseases; Preparations to induce self-tolerance
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/46Cellular immunotherapy
    • A61K39/464Cellular immunotherapy characterised by the antigen targeted or presented
    • A61K39/4643Vertebrate antigens
    • A61K39/46434Antigens related to induction of tolerance to non-self
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/06Immunosuppressants, e.g. drugs for graft rejection
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705Receptors; Cell surface antigens; Cell surface determinants
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2875Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the NGF/TNF superfamily, e.g. CD70, CD95L, CD153, CD154
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/505Medicinal preparations containing antigens or antibodies comprising antibodies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2239/00Indexing codes associated with cellular immunotherapy of group A61K39/46
    • A61K2239/26Universal/off- the- shelf cellular immunotherapy; Allogenic cells or means to avoid rejection
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2239/00Indexing codes associated with cellular immunotherapy of group A61K39/46
    • A61K2239/31Indexing codes associated with cellular immunotherapy of group A61K39/46 characterized by the route of administration
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2239/00Indexing codes associated with cellular immunotherapy of group A61K39/46
    • A61K2239/38Indexing codes associated with cellular immunotherapy of group A61K39/46 characterised by the dose, timing or administration schedule
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/70Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/73Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
LT96-165A 1994-04-25 1996-11-25 Receptoriaus antagonisto panaudojimas t-ląstelių tolerancijai sukelti audinių arba organų transplantacijoje LT4309B (lt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US08/234,987 US5683693A (en) 1994-04-25 1994-04-25 Method for inducing T cell unresponsiveness to a tissue or organ graft with anti-CD40 ligand antibody or soluble CD40

Publications (2)

Publication Number Publication Date
LT96165A LT96165A (en) 1997-11-25
LT4309B true LT4309B (lt) 1998-03-25

Family

ID=22883593

Family Applications (1)

Application Number Title Priority Date Filing Date
LT96-165A LT4309B (lt) 1994-04-25 1996-11-25 Receptoriaus antagonisto panaudojimas t-ląstelių tolerancijai sukelti audinių arba organų transplantacijoje

Country Status (34)

Country Link
US (4) US5683693A (fr)
EP (2) EP0757557B1 (fr)
JP (1) JP2974415B2 (fr)
KR (1) KR100468330B1 (fr)
CN (1) CN1134266C (fr)
AP (1) AP764A (fr)
AT (1) ATE288281T1 (fr)
AU (1) AU710925B2 (fr)
BG (1) BG62121B1 (fr)
BR (1) BR9507509A (fr)
CA (1) CA2188672A1 (fr)
CZ (1) CZ291266B6 (fr)
DE (1) DE69533984T2 (fr)
DK (1) DK0757557T3 (fr)
EE (1) EE03516B1 (fr)
ES (1) ES2237757T3 (fr)
FI (1) FI118792B (fr)
GE (1) GEP20022648B (fr)
HU (1) HU221752B1 (fr)
IS (1) IS2118B (fr)
LT (1) LT4309B (fr)
LV (1) LV11785B (fr)
MD (1) MD1444B2 (fr)
NO (2) NO319787B1 (fr)
NZ (1) NZ284905A (fr)
OA (1) OA10591A (fr)
PL (1) PL180031B1 (fr)
PT (1) PT757557E (fr)
RO (1) RO114743B1 (fr)
RU (1) RU2169009C2 (fr)
SI (1) SI9520057A (fr)
SK (1) SK136996A3 (fr)
UA (1) UA44892C2 (fr)
WO (1) WO1995028957A2 (fr)

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EP1289554A4 (fr) * 2000-06-02 2004-05-26 Univ Minnesota Procede immunotherapeutique permettant de prevenir le rejet de cellules insulaires
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US20040022787A1 (en) 2000-07-03 2004-02-05 Robert Cohen Methods for treating an autoimmune disease using a soluble CTLA4 molecule and a DMARD or NSAID
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WO2002078743A1 (fr) * 2001-02-16 2002-10-10 University Of Rochester Compositions et techniques permettant de reduire les reactions aux transfusions
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Also Published As

Publication number Publication date
JP2974415B2 (ja) 1999-11-10
HU9602924D0 (en) 1996-12-30
EP0757557B1 (fr) 2005-02-02
AU2358595A (en) 1995-11-16
RU2169009C2 (ru) 2001-06-20
DE69533984T2 (de) 2006-04-27
ATE288281T1 (de) 2005-02-15
EP1530973A3 (fr) 2006-12-27
CZ291266B6 (cs) 2003-01-15
CZ312596A3 (en) 1997-03-12
RO114743B1 (ro) 1999-07-30
AU710925B2 (en) 1999-09-30
US6375950B1 (en) 2002-04-23
PL317022A1 (en) 1997-03-03
BR9507509A (pt) 1997-02-02
LT96165A (en) 1997-11-25
NO964440D0 (no) 1996-10-18
US7501124B2 (en) 2009-03-10
CA2188672A1 (fr) 1995-11-02
WO1995028957A3 (fr) 1995-11-23
HU221752B1 (hu) 2002-12-28
FI964272A0 (fi) 1996-10-23
AP9600906A0 (en) 1997-01-31
WO1995028957A2 (fr) 1995-11-02
EP1530973A2 (fr) 2005-05-18
HUT76091A (en) 1997-06-30
US5902585A (en) 1999-05-11
LV11785B (en) 1998-02-20
MD1444B2 (ro) 2000-04-30
FI118792B (fi) 2008-03-31
NO20051182L (no) 1996-12-23
BG62121B1 (bg) 1999-03-31
IS4378A (is) 1996-10-22
EE9600162A (et) 1997-06-16
US20050152897A1 (en) 2005-07-14
LV11785A (lv) 1997-06-20
KR100468330B1 (ko) 2005-12-30
PT757557E (pt) 2005-05-31
CN1134266C (zh) 2004-01-14
MD970009A (en) 1999-01-31
SK136996A3 (en) 1999-01-11
JPH09512271A (ja) 1997-12-09
GEP20022648B (en) 2002-03-25
NO319787B1 (no) 2005-09-12
CN1150760A (zh) 1997-05-28
DK0757557T3 (da) 2005-05-23
AP764A (en) 1999-09-16
OA10591A (en) 2002-07-15
EE03516B1 (et) 2001-10-15
ES2237757T3 (es) 2005-08-01
EP0757557A1 (fr) 1997-02-12
PL180031B1 (pl) 2000-12-29
BG100991A (en) 1998-01-30
US5683693A (en) 1997-11-04
UA44892C2 (uk) 2002-03-15
DE69533984D1 (de) 2005-03-10
IS2118B (is) 2006-06-15
FI964272A (fi) 1996-12-19
SI9520057A (sl) 1998-06-30
NO964440L (no) 1996-12-23
NZ284905A (en) 2004-10-29

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