FI114793B - 1H-indoli-glyoksyyliamidi-sPLA2-inhibiittoreita - Google Patents

1H-indoli-glyoksyyliamidi-sPLA2-inhibiittoreita Download PDF

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Publication number
FI114793B
FI114793B FI951553A FI951553A FI114793B FI 114793 B FI114793 B FI 114793B FI 951553 A FI951553 A FI 951553A FI 951553 A FI951553 A FI 951553A FI 114793 B FI114793 B FI 114793B
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FI
Finland
Prior art keywords
methyl
oxy
indol
amino
dioxoethyl
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FI951553A
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English (en)
Finnish (fi)
Swedish (sv)
Other versions
FI951553A0 (fi
FI951553A (fi
Inventor
Nicholas James Bach
Robert Delane Dillard
Susan Elizabeth Draheim
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Lilly Co Eli
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Publication of FI951553A publication Critical patent/FI951553A/fi
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Publication of FI114793B publication Critical patent/FI114793B/fi

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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D209/00Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04Indoles; Hydrogenated indoles
    • C07D209/30Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
    • C07D209/42Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D209/00Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04Indoles; Hydrogenated indoles
    • C07D209/10Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/18Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D209/22Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with an aralkyl radical attached to the ring nitrogen atom
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/18Drugs for disorders of the alimentary tract or the digestive system for pancreatic disorders, e.g. pancreatic enzymes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/02Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/16Otologicals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/04Anorexiants; Antiobesity agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/08Antiallergic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system

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  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pulmonology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pain & Pain Management (AREA)
  • Immunology (AREA)
  • Child & Adolescent Psychology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Cardiology (AREA)
  • Rheumatology (AREA)
  • Dermatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Indole Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicinal Preparation (AREA)
FI951553A 1994-04-01 1995-03-31 1H-indoli-glyoksyyliamidi-sPLA2-inhibiittoreita FI114793B (fi)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US22191694A 1994-04-01 1994-04-01
US22191694 1994-04-01

Publications (3)

Publication Number Publication Date
FI951553A0 FI951553A0 (fi) 1995-03-31
FI951553A FI951553A (fi) 1995-10-02
FI114793B true FI114793B (fi) 2004-12-31

Family

ID=22829963

Family Applications (1)

Application Number Title Priority Date Filing Date
FI951553A FI114793B (fi) 1994-04-01 1995-03-31 1H-indoli-glyoksyyliamidi-sPLA2-inhibiittoreita

Country Status (29)

Country Link
US (6) US5654326A (zh)
EP (5) EP0675110B1 (zh)
JP (1) JP3109974B2 (zh)
KR (1) KR100368707B1 (zh)
CN (1) CN1067054C (zh)
AT (2) ATE220394T1 (zh)
AU (1) AU688458B2 (zh)
BR (1) BR9501404A (zh)
CA (1) CA2146097C (zh)
CO (1) CO4370099A1 (zh)
CZ (1) CZ82295A3 (zh)
DE (1) DE69527322T2 (zh)
DK (2) DK1950200T3 (zh)
ES (2) ES2179088T3 (zh)
FI (1) FI114793B (zh)
HU (1) HUT72048A (zh)
IL (1) IL113210A (zh)
MX (1) MX9501608A (zh)
MY (1) MY112897A (zh)
NO (1) NO304186B1 (zh)
NZ (1) NZ270848A (zh)
PE (1) PE18696A1 (zh)
PL (1) PL180523B1 (zh)
PT (1) PT675110E (zh)
RU (1) RU2128169C1 (zh)
SI (1) SI0675110T1 (zh)
TW (1) TW383302B (zh)
UA (1) UA47387C2 (zh)
ZA (1) ZA952693B (zh)

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Also Published As

Publication number Publication date
IL113210A (en) 2001-01-28
AU1621795A (en) 1995-10-12
EP0675110B1 (en) 2002-07-10
ES2179088T3 (es) 2003-01-16
EP1197484A2 (en) 2002-04-17
US6175021B1 (en) 2001-01-16
DE69527322T2 (de) 2003-02-27
EP1081135A2 (en) 2001-03-07
ES2377223T3 (es) 2012-03-23
CZ82295A3 (en) 1995-12-13
FI951553A0 (fi) 1995-03-31
EP0675110A1 (en) 1995-10-04
DK1950200T3 (da) 2012-04-10
PL180523B1 (pl) 2001-02-28
RU2128169C1 (ru) 1999-03-27
JPH07285933A (ja) 1995-10-31
EP1081135A3 (en) 2003-11-05
EP2341045A1 (en) 2011-07-06
MY112897A (en) 2001-10-31
KR100368707B1 (ko) 2003-06-02
EP1950200B1 (en) 2012-01-11
RU95104885A (ru) 1997-04-27
KR950032117A (ko) 1995-12-20
PL307951A1 (en) 1995-10-02
CN1067054C (zh) 2001-06-13
NZ270848A (en) 1997-05-26
CA2146097C (en) 2000-03-21
FI951553A (fi) 1995-10-02
US5919943A (en) 1999-07-06
EP1950200A1 (en) 2008-07-30
BR9501404A (pt) 1996-03-05
ZA952693B (en) 1996-09-30
NO951252D0 (no) 1995-03-31
DK0675110T3 (da) 2002-10-07
SI0675110T1 (en) 2002-12-31
UA47387C2 (uk) 2002-07-15
HU9500957D0 (en) 1995-05-29
US5654326A (en) 1997-08-05
TW383302B (en) 2000-03-01
CO4370099A1 (es) 1996-10-07
PT675110E (pt) 2002-11-29
ATE220394T1 (de) 2002-07-15
IL113210A0 (en) 1995-06-29
US6433001B1 (en) 2002-08-13
MX9501608A (es) 1997-02-28
US5919810A (en) 1999-07-06
CN1114310A (zh) 1996-01-03
PE18696A1 (es) 1996-05-30
CA2146097A1 (en) 1995-10-02
DE69527322D1 (de) 2002-08-14
AU688458B2 (en) 1998-03-12
US5733923A (en) 1998-03-31
NO951252L (no) 1995-10-02
NO304186B1 (no) 1998-11-09
ATE540923T1 (de) 2012-01-15
HUT72048A (en) 1996-03-28
JP3109974B2 (ja) 2000-11-20

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