FI110939B - N-substituoitu-1-alkyylitio-2-nitroeteeniamiinin ja sen suolan valmistus - Google Patents

N-substituoitu-1-alkyylitio-2-nitroeteeniamiinin ja sen suolan valmistus Download PDF

Info

Publication number
FI110939B
FI110939B FI901696A FI901696A FI110939B FI 110939 B FI110939 B FI 110939B FI 901696 A FI901696 A FI 901696A FI 901696 A FI901696 A FI 901696A FI 110939 B FI110939 B FI 110939B
Authority
FI
Finland
Prior art keywords
formula
dimethylaminomethyl
process according
methyl
compound
Prior art date
Application number
FI901696A
Other languages
English (en)
Finnish (fi)
Swedish (sv)
Other versions
FI901696A0 (fi
Inventor
Arthur Jackson
Graham Heyes
James Ian Grayson
Paul Edward Rowney
Original Assignee
Glaxo Group Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Glaxo Group Ltd filed Critical Glaxo Group Ltd
Publication of FI901696A0 publication Critical patent/FI901696A0/fi
Application granted granted Critical
Publication of FI110939B publication Critical patent/FI110939B/fi

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
    • C07D317/44—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D317/46—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems condensed with one six-membered ring
    • C07D317/48—Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring
    • C07D317/50—Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to atoms of the carbocyclic ring
    • C07D317/58—Radicals substituted by nitrogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C319/00—Preparation of thiols, sulfides, hydropolysulfides or polysulfides
    • C07C319/22—Preparation of thiols, sulfides, hydropolysulfides or polysulfides of hydropolysulfides or polysulfides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
    • C07C323/23—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton
    • C07C323/24—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton
    • C07C323/27—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being acyclic and unsaturated
FI901696A 1989-04-05 1990-04-04 N-substituoitu-1-alkyylitio-2-nitroeteeniamiinin ja sen suolan valmistus FI110939B (fi)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB898907700A GB8907700D0 (en) 1989-04-05 1989-04-05 Preparation of substituted ethenes
GB8907700 1989-04-05

Publications (2)

Publication Number Publication Date
FI901696A0 FI901696A0 (fi) 1990-04-04
FI110939B true FI110939B (fi) 2003-04-30

Family

ID=10654520

Family Applications (2)

Application Number Title Priority Date Filing Date
FI901696A FI110939B (fi) 1989-04-05 1990-04-04 N-substituoitu-1-alkyylitio-2-nitroeteeniamiinin ja sen suolan valmistus
FI914672A FI914672A0 (fi) 1989-04-05 1991-10-04 Framstaellning av substituerade eten.

Family Applications After (1)

Application Number Title Priority Date Filing Date
FI914672A FI914672A0 (fi) 1989-04-05 1991-10-04 Framstaellning av substituerade eten.

Country Status (25)

Country Link
US (2) US5371247A (ja)
EP (1) EP0466733B1 (ja)
JP (2) JP2954270B2 (ja)
KR (2) KR920701140A (ja)
AT (2) ATE110055T1 (ja)
BE (1) BE1003124A5 (ja)
CA (2) CA2013841C (ja)
CH (1) CH681008A5 (ja)
DE (2) DE4010888C2 (ja)
DK (2) DK84390A (ja)
ES (2) ES2057549T3 (ja)
FI (2) FI110939B (ja)
FR (1) FR2645535B1 (ja)
GB (2) GB8907700D0 (ja)
GR (1) GR1001302B (ja)
HU (3) HU9203905D0 (ja)
IE (2) IE61894B1 (ja)
IL (1) IL94002A (ja)
IN (3) IN170319B (ja)
IT (1) IT1242481B (ja)
NL (1) NL194699C (ja)
PT (1) PT93659B (ja)
SE (1) SE509459C2 (ja)
WO (1) WO1990012002A1 (ja)
ZA (1) ZA902592B (ja)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8907700D0 (en) * 1989-04-05 1989-05-17 Fine Organics Ltd Preparation of substituted ethenes
NZ245015A (en) * 1991-11-05 1995-12-21 Transkaryotic Therapies Inc Delivery of human growth hormone through the administration of transfected cell lines encoding human growth hormone, which are physically protected from host immune response; the transfected cells and their production
US5686588A (en) * 1995-08-16 1997-11-11 Yoo; Seo Hong Amine acid salt compounds and process for the production thereof
AU2001264174A1 (en) 2000-04-21 2001-11-07 Ioannis Pallikaris Device for the shaping of a substance on the surface of a cornea
CN104119257B (zh) * 2013-04-26 2016-08-03 石家庄康坦福化工科技有限公司 一种1-甲胺基-1-甲硫基-2-硝基乙烯的制备方法

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1554153A (en) * 1975-05-15 1979-10-17 Smith Kline French Lab Process for making 2-amino-2-alkylthionitroethylenes
IT1168163B (it) * 1981-08-18 1987-05-20 Ausonia Farma Srl Composto ad attivita' antiulcera, procedimento per la sua preparazione e composizioni farmaceutiche relative
PT76557B (en) * 1982-04-16 1986-01-21 Inke Sa Process for preparing furan derivatives and addition salts thereof and of pharmaceutical compositions containing the same
ES523448A0 (es) * 1983-06-21 1984-11-16 Union Quimico Farma Procedimiento para la obtencion de n-metil-1-metiltio-2-nitroetenamina
GB8415254D0 (en) * 1984-06-15 1984-07-18 Glaxo Group Ltd Amine derivatives
ES2003781A6 (es) * 1987-02-06 1988-11-16 Unio Quimico Farmaceutica S A Procedimiento para la obtencion de n-metil-1-metiltio-2-nitroetenamina
GB8907700D0 (en) * 1989-04-05 1989-05-17 Fine Organics Ltd Preparation of substituted ethenes

Also Published As

Publication number Publication date
IE901222L (en) 1990-10-05
CA2013841C (en) 1999-10-12
FI901696A0 (fi) 1990-04-04
HU207991B (en) 1993-07-28
KR920701140A (ko) 1992-08-11
KR900016119A (ko) 1990-11-12
HU902080D0 (en) 1990-07-28
SE9001236L (sv) 1990-10-06
IE901221L (en) 1990-10-05
US5112995A (en) 1992-05-12
IE65395B1 (en) 1995-10-18
ATE110055T1 (de) 1994-09-15
EP0466733A1 (en) 1992-01-22
DE4010888C2 (de) 2001-01-18
GR1001302B (el) 1993-07-30
SE9001236D0 (sv) 1990-04-04
HUT58285A (en) 1992-02-28
PT93659A (pt) 1990-11-20
GB9007568D0 (en) 1990-05-30
DK0466733T3 (da) 1994-09-19
DK84390D0 (da) 1990-04-04
IT9047829A0 (it) 1990-04-04
IT1242481B (it) 1994-03-17
NL9000790A (nl) 1990-11-01
JP3003946B2 (ja) 2000-01-31
ES2019246A6 (es) 1991-06-01
HU9203905D0 (en) 1993-04-28
IN170319B (ja) 1992-03-14
KR0147820B1 (ko) 1998-08-17
FR2645535B1 (fr) 1992-06-19
NL194699C (nl) 2002-12-03
JP2954270B2 (ja) 1999-09-27
FI914672A0 (fi) 1991-10-04
ZA902592B (en) 1991-04-24
HU902945D0 (en) 1991-12-30
IE61894B1 (en) 1994-11-30
PT93659B (pt) 1996-08-30
CA2013841A1 (en) 1990-10-05
DK84390A (da) 1990-10-06
JPH04504254A (ja) 1992-07-30
IT9047829A1 (it) 1991-10-04
IL94002A (en) 1994-11-11
GB2230526A (en) 1990-10-24
IN173647B (ja) 1994-06-18
US5371247A (en) 1994-12-06
CH681008A5 (ja) 1992-12-31
BE1003124A5 (fr) 1991-12-03
WO1990012002A1 (en) 1990-10-18
GB2230526B (en) 1992-05-27
GB8907700D0 (en) 1989-05-17
GR900100250A (en) 1991-09-27
SE509459C2 (sv) 1999-02-01
DE69011677T2 (de) 1995-02-09
DE4010888A1 (de) 1990-10-11
IN173648B (ja) 1994-06-18
ATA80090A (ja) 1995-01-15
FR2645535A1 (fr) 1990-10-12
EP0466733B1 (en) 1994-08-17
CA2046293C (en) 1999-01-05
HUT54977A (en) 1991-04-29
CA2046293A1 (en) 1990-10-06
AT400030B (de) 1995-09-25
DE69011677D1 (de) 1994-09-22
ES2057549T3 (es) 1994-10-16
JPH0368569A (ja) 1991-03-25
NL194699B (nl) 2002-08-01
IL94002A0 (en) 1991-01-31

Similar Documents

Publication Publication Date Title
FI110939B (fi) N-substituoitu-1-alkyylitio-2-nitroeteeniamiinin ja sen suolan valmistus
KR890011904A (ko) 안드로스타-1,4, -디엔-3,17-디온의 6-메틸렌 유도체 합성방법
FI85273B (fi) Foerfarande foer framstaellning av terapeutiskt anvaendbara pyrimidinderivat.
US3825594A (en) Bis(trifluoromethyl)benzamides
KR840002441B1 (ko) 과니딘의 헤테로사이클 유도체의 제조방법
FI90419B (fi) Menetelmä 1- 2-/5-dimetyyliaminometyyli-2-(furyylimetyylitio)etyyli/ amino-1-metyyliamino-2-nitroeteenin ja sen hydrokloridin valmistamiseksi
Fuchigami et al. N-Halogen Compounds of Cyanamide Derivatives. V. The Preparation and Reaction of Δ 4-1, 2, 4-Thiadiazolines
FI89596B (fi) Foerfarande foer framstaellning av ranitidin eller syraadditionssalter daerav
HU213264B (en) Method for producing n,n'disubstituted, 2 nitro 1,1-ethene-diamines
Bhasin et al. Synthesis and evaluation of Schiff and N-Mannich bases of isatin as potential antimicrobial agents
KR20000068410A (ko) 아미딘의 제조 방법
GB1596376A (en) 4,5-disubstituted imidazole-2-thiones processes for their preparation and their use as intermediates
HU182272B (en) Process for preparing rhanitidine
US4216150A (en) Preparation of pyrrole-2-acetates
FI90061C (fi) Foerfarande foer framstaellning av aminderivat
Rehse et al. Platelet Aggregation Inhibiting and Anticoagulant Effects of Oligoamines, XIX: 4, 4′‐Phenylene‐bis‐sydnone Imines
KR840002440B1 (ko) 과니딘의 해태로 싸이클 유도체의 제조방법
Parushev et al. Synthesis of polysubstituted 2, 4-dimethylquinolines as potential antimalarial drugs
JPS62142179A (ja) マイトマイシン誘導体の製造法
CZ20001348A3 (cs) Způsob přípravy pirlindolhydrochloridu
GB1565968A (en) N-(2-mercaptoethyl)-n'-methyl-2-nitro-1,1-ethenediamines
CS226943B1 (cs) Bis(2-dimetylaminoetyl)alkylamíny a sposob ich přípravy

Legal Events

Date Code Title Description
FG Patent granted

Owner name: GLAXO GROUP LIMITED