FI110186B - Menetelmä terapeuttisesti aktiivisten 2-{3-[4-(3-kloorifenyyli)-1-piperatsinyyli]propyyli}-1,2,4-triatsoli[4,3-a]pyridin-3-(2H) onijohdannaisten valmistamiseksi - Google Patents

Menetelmä terapeuttisesti aktiivisten 2-{3-[4-(3-kloorifenyyli)-1-piperatsinyyli]propyyli}-1,2,4-triatsoli[4,3-a]pyridin-3-(2H) onijohdannaisten valmistamiseksi Download PDF

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Publication number
FI110186B
FI110186B FI943386A FI943386A FI110186B FI 110186 B FI110186 B FI 110186B FI 943386 A FI943386 A FI 943386A FI 943386 A FI943386 A FI 943386A FI 110186 B FI110186 B FI 110186B
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FI
Finland
Prior art keywords
formula
chlorophenyl
group
triazole
compound
Prior art date
Application number
FI943386A
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English (en)
Finnish (fi)
Swedish (sv)
Other versions
FI943386A (fi
FI943386A0 (fi
Inventor
Leandro Baiocchi
Original Assignee
Angelini Ricerche Spa
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Publication date
Application filed by Angelini Ricerche Spa filed Critical Angelini Ricerche Spa
Publication of FI943386A publication Critical patent/FI943386A/fi
Publication of FI943386A0 publication Critical patent/FI943386A0/fi
Application granted granted Critical
Publication of FI110186B publication Critical patent/FI110186B/fi

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/06—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by halogen atoms or nitro radicals
    • C07D295/073—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by halogen atoms or nitro radicals with the ring nitrogen atoms and the substituents separated by carbocyclic rings or by carbon chains interrupted by carbocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/26—Psychostimulants, e.g. nicotine, cocaine
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C229/02—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton
    • C07C229/04—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated
    • C07C229/06—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one amino and one carboxyl group bound to the carbon skeleton
    • C07C229/10—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one amino and one carboxyl group bound to the carbon skeleton the nitrogen atom of the amino group being further bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings
    • C07C229/16—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one amino and one carboxyl group bound to the carbon skeleton the nitrogen atom of the amino group being further bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings to carbon atoms of hydrocarbon radicals substituted by amino or carboxyl groups, e.g. ethylenediamine-tetra-acetic acid, iminodiacetic acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/06—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by halogen atoms or nitro radicals
    • C07D295/067—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by halogen atoms or nitro radicals with the ring nitrogen atoms and the substituents attached to the same carbon chain, which is not interrupted by carbocyclic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Psychiatry (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
FI943386A 1992-01-17 1994-07-15 Menetelmä terapeuttisesti aktiivisten 2-{3-[4-(3-kloorifenyyli)-1-piperatsinyyli]propyyli}-1,2,4-triatsoli[4,3-a]pyridin-3-(2H) onijohdannaisten valmistamiseksi FI110186B (fi)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
ITMI920084 1992-01-17
ITMI920084A IT1258790B (it) 1992-01-17 1992-01-17 Alchil derivati del trazodone
EP9300080 1993-01-14
PCT/EP1993/000080 WO1993014091A1 (fr) 1992-01-17 1993-01-14 Derives alkyles de trazodone influant sur le systeme nerveux central

Publications (3)

Publication Number Publication Date
FI943386A FI943386A (fi) 1994-07-15
FI943386A0 FI943386A0 (fi) 1994-07-15
FI110186B true FI110186B (fi) 2002-12-13

Family

ID=11361589

Family Applications (2)

Application Number Title Priority Date Filing Date
FI943386A FI110186B (fi) 1992-01-17 1994-07-15 Menetelmä terapeuttisesti aktiivisten 2-{3-[4-(3-kloorifenyyli)-1-piperatsinyyli]propyyli}-1,2,4-triatsoli[4,3-a]pyridin-3-(2H) onijohdannaisten valmistamiseksi
FI20021652A FI113266B (fi) 1992-01-17 2002-09-16 Tratsodonin alkyylijohdannaisten valmistuksessa käyttökelpoisia välituotteita

Family Applications After (1)

Application Number Title Priority Date Filing Date
FI20021652A FI113266B (fi) 1992-01-17 2002-09-16 Tratsodonin alkyylijohdannaisten valmistuksessa käyttökelpoisia välituotteita

Country Status (25)

Country Link
EP (1) EP0623131B1 (fr)
JP (1) JP2856912B2 (fr)
KR (1) KR100254690B1 (fr)
AT (1) ATE136307T1 (fr)
AU (1) AU671973B2 (fr)
BG (1) BG61841B1 (fr)
BR (1) BR9305752A (fr)
CA (1) CA2128202C (fr)
CZ (1) CZ282910B6 (fr)
DE (1) DE69302087T2 (fr)
DK (1) DK0623131T3 (fr)
ES (1) ES2088270T3 (fr)
FI (2) FI110186B (fr)
GE (1) GEP20001939B (fr)
GR (1) GR3020420T3 (fr)
HU (5) HU218678B (fr)
IT (1) IT1258790B (fr)
NO (2) NO302365B1 (fr)
NZ (1) NZ246598A (fr)
PL (1) PL170913B1 (fr)
RO (1) RO113465B1 (fr)
RU (1) RU2126801C1 (fr)
SK (1) SK280561B6 (fr)
WO (1) WO1993014091A1 (fr)
ZA (1) ZA93292B (fr)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU718075B2 (en) * 1993-07-01 2000-04-06 Angelini Ricerche S.P.A. Societa Consortile Intermediates for the preparation of pharmacologically active enantiomers of triazolone compounds
IT1268414B1 (it) * 1993-07-01 1997-02-27 Angelini Francesco Ist Ricerca Enantiomeri farmacologicamente attivi
TW200726765A (en) * 2005-06-17 2007-07-16 Bristol Myers Squibb Co Triazolopyridine cannabinoid receptor 1 antagonists
ITMI20051193A1 (it) 2005-06-24 2006-12-25 Acraf Uso farmaceutico di una 1-3-clorofenil-3-alchilpiperazina
WO2012072665A1 (fr) 2010-11-30 2012-06-07 Pharmaneuroboost N.V. Compositions comprenant de la pipampérone et des antagonistes/inhibiteurs de la recapture de la sérotonine
RU2706700C1 (ru) 2019-09-24 2019-11-20 Общество с ограниченной ответственностью "Научно-производственная компания "СКиФФ" Фармацевтическая композиция для коррекции поведения кошек и собак в стрессовых ситуациях

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US100505A (en) * 1870-03-08 Improvement in sash-bolt
IT1066857B (it) * 1965-12-15 1985-03-12 Acraf Derivati della s ipiazolo 4.3 a piridina e processi per la loro preparazione

Also Published As

Publication number Publication date
SK280561B6 (sk) 2000-03-13
CZ282910B6 (cs) 1997-11-12
HU9502179D0 (en) 1995-09-28
HUT71511A (en) 1995-12-28
FI20021652A (fi) 2002-09-16
NO974462D0 (no) 1997-09-26
FI113266B (fi) 2004-03-31
HU217968B (hu) 2000-05-28
NO302365B1 (no) 1998-02-23
HU217981B (hu) 2000-05-28
SK84694A3 (en) 1995-04-12
GEP20001939B (en) 2000-02-05
HUT70761A (en) 1995-10-30
RO113465B1 (ro) 1998-07-30
NO942668L (no) 1994-09-16
ES2088270T3 (es) 1996-08-01
HU9502178D0 (en) 1995-09-28
HU9502180D0 (en) 1995-09-28
RU2126801C1 (ru) 1999-02-27
ATE136307T1 (de) 1996-04-15
JPH07503000A (ja) 1995-03-30
WO1993014091A1 (fr) 1993-07-22
NO303686B1 (no) 1998-08-17
ZA93292B (en) 1993-08-19
ITMI920084A0 (it) 1992-01-17
DE69302087T2 (de) 1996-11-28
NZ246598A (en) 1997-08-22
CA2128202A1 (fr) 1993-07-22
JP2856912B2 (ja) 1999-02-10
HUT71513A (en) 1995-12-28
CA2128202C (fr) 2001-01-23
HU219493B (hu) 2001-04-28
CZ173294A3 (en) 1995-02-15
HU217982B (hu) 2000-05-28
AU3350493A (en) 1993-08-03
ITMI920084A1 (it) 1993-07-17
HUT71512A (en) 1995-12-28
EP0623131B1 (fr) 1996-04-03
IT1258790B (it) 1996-02-29
HU218678B (hu) 2000-10-28
FI943386A (fi) 1994-07-15
HU9502177D0 (en) 1995-09-28
NO974462L (no) 1994-09-16
DE69302087D1 (de) 1996-05-09
BG61841B1 (bg) 1998-07-31
PL170913B1 (pl) 1997-02-28
RU94036769A (ru) 1997-04-20
NO942668D0 (no) 1994-07-15
GR3020420T3 (en) 1996-10-31
BR9305752A (pt) 1997-01-28
BG98896A (bg) 1995-03-31
HU9402119D0 (en) 1994-09-28
HUT72591A (en) 1996-05-28
KR100254690B1 (ko) 2000-05-01
EP0623131A1 (fr) 1994-11-09
DK0623131T3 (da) 1996-08-05
AU671973B2 (en) 1996-09-19
FI943386A0 (fi) 1994-07-15

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Owner name: ANGELINI RICERCHE S.P.A.