FI943386A0 - CNS-aktiivisuuden omaavia tratsodonin alkyylijohdannaisia - Google Patents

CNS-aktiivisuuden omaavia tratsodonin alkyylijohdannaisia

Info

Publication number
FI943386A0
FI943386A0 FI943386A FI943386A FI943386A0 FI 943386 A0 FI943386 A0 FI 943386A0 FI 943386 A FI943386 A FI 943386A FI 943386 A FI943386 A FI 943386A FI 943386 A0 FI943386 A0 FI 943386A0
Authority
FI
Finland
Prior art keywords
trazodone
alkyl derivatives
cns activity
cns
activity
Prior art date
Application number
FI943386A
Other languages
English (en)
Swedish (sv)
Other versions
FI110186B (fi
FI943386A (fi
Inventor
Leandro Baiocchi
Original Assignee
Angelini Francesco Ist Ricerca
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Angelini Francesco Ist Ricerca filed Critical Angelini Francesco Ist Ricerca
Publication of FI943386A0 publication Critical patent/FI943386A0/fi
Publication of FI943386A publication Critical patent/FI943386A/fi
Application granted granted Critical
Publication of FI110186B publication Critical patent/FI110186B/fi

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/06—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by halogen atoms or nitro radicals
    • C07D295/073—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by halogen atoms or nitro radicals with the ring nitrogen atoms and the substituents separated by carbocyclic rings or by carbon chains interrupted by carbocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/26—Psychostimulants, e.g. nicotine, cocaine
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C229/02—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton
    • C07C229/04—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated
    • C07C229/06—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one amino and one carboxyl group bound to the carbon skeleton
    • C07C229/10—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one amino and one carboxyl group bound to the carbon skeleton the nitrogen atom of the amino group being further bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings
    • C07C229/16—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one amino and one carboxyl group bound to the carbon skeleton the nitrogen atom of the amino group being further bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings to carbon atoms of hydrocarbon radicals substituted by amino or carboxyl groups, e.g. ethylenediamine-tetra-acetic acid, iminodiacetic acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/06—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by halogen atoms or nitro radicals
    • C07D295/067—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by halogen atoms or nitro radicals with the ring nitrogen atoms and the substituents attached to the same carbon chain, which is not interrupted by carbocyclic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
FI943386A 1992-01-17 1994-07-15 Menetelmä terapeuttisesti aktiivisten 2-{3-[4-(3-kloorifenyyli)-1-piperatsinyyli]propyyli}-1,2,4-triatsoli[4,3-a]pyridin-3-(2H) onijohdannaisten valmistamiseksi FI110186B (fi)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
ITMI920084 1992-01-17
ITMI920084A IT1258790B (it) 1992-01-17 1992-01-17 Alchil derivati del trazodone
EP9300080 1993-01-14
PCT/EP1993/000080 WO1993014091A1 (en) 1992-01-17 1993-01-14 Alkyl derivatives of trazodone with cns activity

Publications (3)

Publication Number Publication Date
FI943386A0 true FI943386A0 (fi) 1994-07-15
FI943386A FI943386A (fi) 1994-07-15
FI110186B FI110186B (fi) 2002-12-13

Family

ID=11361589

Family Applications (2)

Application Number Title Priority Date Filing Date
FI943386A FI110186B (fi) 1992-01-17 1994-07-15 Menetelmä terapeuttisesti aktiivisten 2-{3-[4-(3-kloorifenyyli)-1-piperatsinyyli]propyyli}-1,2,4-triatsoli[4,3-a]pyridin-3-(2H) onijohdannaisten valmistamiseksi
FI20021652A FI113266B (fi) 1992-01-17 2002-09-16 Tratsodonin alkyylijohdannaisten valmistuksessa käyttökelpoisia välituotteita

Family Applications After (1)

Application Number Title Priority Date Filing Date
FI20021652A FI113266B (fi) 1992-01-17 2002-09-16 Tratsodonin alkyylijohdannaisten valmistuksessa käyttökelpoisia välituotteita

Country Status (25)

Country Link
EP (1) EP0623131B1 (fi)
JP (1) JP2856912B2 (fi)
KR (1) KR100254690B1 (fi)
AT (1) ATE136307T1 (fi)
AU (1) AU671973B2 (fi)
BG (1) BG61841B1 (fi)
BR (1) BR9305752A (fi)
CA (1) CA2128202C (fi)
CZ (1) CZ282910B6 (fi)
DE (1) DE69302087T2 (fi)
DK (1) DK0623131T3 (fi)
ES (1) ES2088270T3 (fi)
FI (2) FI110186B (fi)
GE (1) GEP20001939B (fi)
GR (1) GR3020420T3 (fi)
HU (5) HU218678B (fi)
IT (1) IT1258790B (fi)
NO (2) NO302365B1 (fi)
NZ (1) NZ246598A (fi)
PL (1) PL170913B1 (fi)
RO (1) RO113465B1 (fi)
RU (1) RU2126801C1 (fi)
SK (1) SK280561B6 (fi)
WO (1) WO1993014091A1 (fi)
ZA (1) ZA93292B (fi)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU718075B2 (en) * 1993-07-01 2000-04-06 Angelini Ricerche S.P.A. Societa Consortile Intermediates for the preparation of pharmacologically active enantiomers of triazolone compounds
IT1268414B1 (it) * 1993-07-01 1997-02-27 Angelini Francesco Ist Ricerca Enantiomeri farmacologicamente attivi
US7572808B2 (en) 2005-06-17 2009-08-11 Bristol-Myers Squibb Company Triazolopyridine cannabinoid receptor 1 antagonists
ITMI20051193A1 (it) * 2005-06-24 2006-12-25 Acraf Uso farmaceutico di una 1-3-clorofenil-3-alchilpiperazina
WO2012072665A1 (en) 2010-11-30 2012-06-07 Pharmaneuroboost N.V. Compositions comprising pipamperone and serotonin antagonist reuptake inhibitors
RU2706700C1 (ru) 2019-09-24 2019-11-20 Общество с ограниченной ответственностью "Научно-производственная компания "СКиФФ" Фармацевтическая композиция для коррекции поведения кошек и собак в стрессовых ситуациях

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US100505A (en) * 1870-03-08 Improvement in sash-bolt
IT1066857B (it) * 1965-12-15 1985-03-12 Acraf Derivati della s ipiazolo 4.3 a piridina e processi per la loro preparazione

Also Published As

Publication number Publication date
JP2856912B2 (ja) 1999-02-10
HU217982B (hu) 2000-05-28
HUT71513A (en) 1995-12-28
KR100254690B1 (ko) 2000-05-01
HU9502179D0 (en) 1995-09-28
RO113465B1 (ro) 1998-07-30
BG61841B1 (bg) 1998-07-31
HU9402119D0 (en) 1994-09-28
NO942668D0 (no) 1994-07-15
HU9502180D0 (en) 1995-09-28
CZ173294A3 (en) 1995-02-15
NO303686B1 (no) 1998-08-17
CA2128202A1 (en) 1993-07-22
NZ246598A (en) 1997-08-22
HUT71512A (en) 1995-12-28
ITMI920084A0 (it) 1992-01-17
BG98896A (bg) 1995-03-31
PL170913B1 (pl) 1997-02-28
DE69302087T2 (de) 1996-11-28
RU2126801C1 (ru) 1999-02-27
CZ282910B6 (cs) 1997-11-12
HUT70761A (en) 1995-10-30
ITMI920084A1 (it) 1993-07-17
ES2088270T3 (es) 1996-08-01
RU94036769A (ru) 1997-04-20
JPH07503000A (ja) 1995-03-30
WO1993014091A1 (en) 1993-07-22
AU3350493A (en) 1993-08-03
EP0623131B1 (en) 1996-04-03
BR9305752A (pt) 1997-01-28
FI110186B (fi) 2002-12-13
DK0623131T3 (da) 1996-08-05
SK84694A3 (en) 1995-04-12
GEP20001939B (en) 2000-02-05
IT1258790B (it) 1996-02-29
AU671973B2 (en) 1996-09-19
FI943386A (fi) 1994-07-15
SK280561B6 (sk) 2000-03-13
HUT71511A (en) 1995-12-28
HU9502178D0 (en) 1995-09-28
ZA93292B (en) 1993-08-19
CA2128202C (en) 2001-01-23
FI113266B (fi) 2004-03-31
EP0623131A1 (en) 1994-11-09
NO302365B1 (no) 1998-02-23
DE69302087D1 (de) 1996-05-09
HU9502177D0 (en) 1995-09-28
HU217981B (hu) 2000-05-28
GR3020420T3 (en) 1996-10-31
ATE136307T1 (de) 1996-04-15
FI20021652A (fi) 2002-09-16
HUT72591A (en) 1996-05-28
HU219493B (hu) 2001-04-28
HU218678B (hu) 2000-10-28
NO974462D0 (no) 1997-09-26
HU217968B (hu) 2000-05-28
NO942668L (no) 1994-09-16
NO974462L (no) 1994-09-16

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Owner name: ANGELINI RICERCHE S.P.A.