DK0623131T3 - Alkylderivater af trazodon med CNS-aktivitet - Google Patents

Alkylderivater af trazodon med CNS-aktivitet

Info

Publication number
DK0623131T3
DK0623131T3 DK93902204.2T DK93902204T DK0623131T3 DK 0623131 T3 DK0623131 T3 DK 0623131T3 DK 93902204 T DK93902204 T DK 93902204T DK 0623131 T3 DK0623131 T3 DK 0623131T3
Authority
DK
Denmark
Prior art keywords
trazodone
alkyl derivatives
cns activity
cns
activity
Prior art date
Application number
DK93902204.2T
Other languages
Danish (da)
English (en)
Inventor
Leandro Baiocchi
Original Assignee
Angelini Ricerche Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Angelini Ricerche Spa filed Critical Angelini Ricerche Spa
Application granted granted Critical
Publication of DK0623131T3 publication Critical patent/DK0623131T3/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D295/00Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/06Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by halogen atoms or nitro radicals
    • C07D295/073Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by halogen atoms or nitro radicals with the ring nitrogen atoms and the substituents separated by carbocyclic rings or by carbon chains interrupted by carbocyclic rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/24Antidepressants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/26Psychostimulants, e.g. nicotine, cocaine
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C229/00Compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C229/02Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton
    • C07C229/04Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated
    • C07C229/06Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one amino and one carboxyl group bound to the carbon skeleton
    • C07C229/10Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one amino and one carboxyl group bound to the carbon skeleton the nitrogen atom of the amino group being further bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings
    • C07C229/16Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one amino and one carboxyl group bound to the carbon skeleton the nitrogen atom of the amino group being further bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings to carbon atoms of hydrocarbon radicals substituted by amino or carboxyl groups, e.g. ethylenediamine-tetra-acetic acid, iminodiacetic acids
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D295/00Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/06Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by halogen atoms or nitro radicals
    • C07D295/067Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by halogen atoms or nitro radicals with the ring nitrogen atoms and the substituents attached to the same carbon chain, which is not interrupted by carbocyclic rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04Ortho-condensed systems
DK93902204.2T 1992-01-17 1993-01-14 Alkylderivater af trazodon med CNS-aktivitet DK0623131T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ITMI920084A IT1258790B (it) 1992-01-17 1992-01-17 Alchil derivati del trazodone

Publications (1)

Publication Number Publication Date
DK0623131T3 true DK0623131T3 (da) 1996-08-05

Family

ID=11361589

Family Applications (1)

Application Number Title Priority Date Filing Date
DK93902204.2T DK0623131T3 (da) 1992-01-17 1993-01-14 Alkylderivater af trazodon med CNS-aktivitet

Country Status (25)

Country Link
EP (1) EP0623131B1 (fi)
JP (1) JP2856912B2 (fi)
KR (1) KR100254690B1 (fi)
AT (1) ATE136307T1 (fi)
AU (1) AU671973B2 (fi)
BG (1) BG61841B1 (fi)
BR (1) BR9305752A (fi)
CA (1) CA2128202C (fi)
CZ (1) CZ282910B6 (fi)
DE (1) DE69302087T2 (fi)
DK (1) DK0623131T3 (fi)
ES (1) ES2088270T3 (fi)
FI (2) FI110186B (fi)
GE (1) GEP20001939B (fi)
GR (1) GR3020420T3 (fi)
HU (5) HU218678B (fi)
IT (1) IT1258790B (fi)
NO (2) NO302365B1 (fi)
NZ (1) NZ246598A (fi)
PL (1) PL170913B1 (fi)
RO (1) RO113465B1 (fi)
RU (1) RU2126801C1 (fi)
SK (1) SK280561B6 (fi)
WO (1) WO1993014091A1 (fi)
ZA (1) ZA93292B (fi)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU718075B2 (en) * 1993-07-01 2000-04-06 Angelini Ricerche S.P.A. Societa Consortile Intermediates for the preparation of pharmacologically active enantiomers of triazolone compounds
IT1268414B1 (it) * 1993-07-01 1997-02-27 Angelini Francesco Ist Ricerca Enantiomeri farmacologicamente attivi
US7572808B2 (en) 2005-06-17 2009-08-11 Bristol-Myers Squibb Company Triazolopyridine cannabinoid receptor 1 antagonists
ITMI20051193A1 (it) * 2005-06-24 2006-12-25 Acraf Uso farmaceutico di una 1-3-clorofenil-3-alchilpiperazina
WO2012072665A1 (en) 2010-11-30 2012-06-07 Pharmaneuroboost N.V. Compositions comprising pipamperone and serotonin antagonist reuptake inhibitors
RU2706700C1 (ru) 2019-09-24 2019-11-20 Общество с ограниченной ответственностью "Научно-производственная компания "СКиФФ" Фармацевтическая композиция для коррекции поведения кошек и собак в стрессовых ситуациях

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US100505A (en) * 1870-03-08 Improvement in sash-bolt
IT1066857B (it) * 1965-12-15 1985-03-12 Acraf Derivati della s ipiazolo 4.3 a piridina e processi per la loro preparazione

Also Published As

Publication number Publication date
JP2856912B2 (ja) 1999-02-10
HU217982B (hu) 2000-05-28
HUT71513A (en) 1995-12-28
KR100254690B1 (ko) 2000-05-01
HU9502179D0 (en) 1995-09-28
RO113465B1 (ro) 1998-07-30
BG61841B1 (bg) 1998-07-31
HU9402119D0 (en) 1994-09-28
NO942668D0 (no) 1994-07-15
HU9502180D0 (en) 1995-09-28
CZ173294A3 (en) 1995-02-15
NO303686B1 (no) 1998-08-17
CA2128202A1 (en) 1993-07-22
NZ246598A (en) 1997-08-22
HUT71512A (en) 1995-12-28
FI943386A0 (fi) 1994-07-15
ITMI920084A0 (it) 1992-01-17
BG98896A (bg) 1995-03-31
PL170913B1 (pl) 1997-02-28
DE69302087T2 (de) 1996-11-28
RU2126801C1 (ru) 1999-02-27
CZ282910B6 (cs) 1997-11-12
HUT70761A (en) 1995-10-30
ITMI920084A1 (it) 1993-07-17
ES2088270T3 (es) 1996-08-01
RU94036769A (ru) 1997-04-20
JPH07503000A (ja) 1995-03-30
WO1993014091A1 (en) 1993-07-22
AU3350493A (en) 1993-08-03
EP0623131B1 (en) 1996-04-03
BR9305752A (pt) 1997-01-28
FI110186B (fi) 2002-12-13
SK84694A3 (en) 1995-04-12
GEP20001939B (en) 2000-02-05
IT1258790B (it) 1996-02-29
AU671973B2 (en) 1996-09-19
FI943386A (fi) 1994-07-15
SK280561B6 (sk) 2000-03-13
HUT71511A (en) 1995-12-28
HU9502178D0 (en) 1995-09-28
ZA93292B (en) 1993-08-19
CA2128202C (en) 2001-01-23
FI113266B (fi) 2004-03-31
EP0623131A1 (en) 1994-11-09
NO302365B1 (no) 1998-02-23
DE69302087D1 (de) 1996-05-09
HU9502177D0 (en) 1995-09-28
HU217981B (hu) 2000-05-28
GR3020420T3 (en) 1996-10-31
ATE136307T1 (de) 1996-04-15
FI20021652A (fi) 2002-09-16
HUT72591A (en) 1996-05-28
HU219493B (hu) 2001-04-28
HU218678B (hu) 2000-10-28
NO974462D0 (no) 1997-09-26
HU217968B (hu) 2000-05-28
NO942668L (no) 1994-09-16
NO974462L (no) 1994-09-16

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