FI109794B - Menetelmä 10-desasetyylibakkatiini-III:n saamiseksi - Google Patents

Menetelmä 10-desasetyylibakkatiini-III:n saamiseksi Download PDF

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Publication number
FI109794B
FI109794B FI951596A FI951596A FI109794B FI 109794 B FI109794 B FI 109794B FI 951596 A FI951596 A FI 951596A FI 951596 A FI951596 A FI 951596A FI 109794 B FI109794 B FI 109794B
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FI
Finland
Prior art keywords
alcohol
taxus
iii
aliphatic
extract
Prior art date
Application number
FI951596A
Other languages
English (en)
Finnish (fi)
Swedish (sv)
Other versions
FI951596A0 (fi
FI951596A (fi
Inventor
Rodolphe Margraff
Bernadette Mandard
Jean-Claude Gaullier
Original Assignee
Rhone Poulenc Rorer Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Rhone Poulenc Rorer Sa filed Critical Rhone Poulenc Rorer Sa
Publication of FI951596A0 publication Critical patent/FI951596A0/fi
Publication of FI951596A publication Critical patent/FI951596A/fi
Application granted granted Critical
Publication of FI109794B publication Critical patent/FI109794B/fi

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D305/00—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms
    • C07D305/14—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms condensed with carbocyclic rings or ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epoxy Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Peptides Or Proteins (AREA)
  • Saccharide Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Fats And Perfumes (AREA)
  • Pyrane Compounds (AREA)
  • Separation Using Semi-Permeable Membranes (AREA)
  • Polyoxymethylene Polymers And Polymers With Carbon-To-Carbon Bonds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Compounds Of Unknown Constitution (AREA)
FI951596A 1992-10-05 1995-04-04 Menetelmä 10-desasetyylibakkatiini-III:n saamiseksi FI109794B (fi)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
FR9211746A FR2696463B1 (fr) 1992-10-05 1992-10-05 Procédé d'obtention de la désacétyl-10 baccatine III.
FR9211746 1992-10-05
FR9300972 1993-10-04
PCT/FR1993/000972 WO1994007882A1 (fr) 1992-10-05 1993-10-04 Procede d'obtention de la desacetyl-10 baccatine iii

Publications (3)

Publication Number Publication Date
FI951596A0 FI951596A0 (fi) 1995-04-04
FI951596A FI951596A (fi) 1995-04-04
FI109794B true FI109794B (fi) 2002-10-15

Family

ID=9434124

Family Applications (1)

Application Number Title Priority Date Filing Date
FI951596A FI109794B (fi) 1992-10-05 1995-04-04 Menetelmä 10-desasetyylibakkatiini-III:n saamiseksi

Country Status (30)

Country Link
US (1) US5393895A (ja)
EP (1) EP0663910B1 (ja)
JP (1) JP3299754B2 (ja)
KR (1) KR100301236B1 (ja)
CN (1) CN1043530C (ja)
AT (1) ATE148883T1 (ja)
AU (1) AU680629B2 (ja)
CA (1) CA2146373C (ja)
CZ (2) CZ284615B6 (ja)
DE (1) DE69308155T2 (ja)
DK (1) DK0663910T3 (ja)
EE (1) EE03126B1 (ja)
ES (1) ES2098061T3 (ja)
FI (1) FI109794B (ja)
FR (1) FR2696463B1 (ja)
GE (1) GEP20001937B (ja)
GR (1) GR3022617T3 (ja)
HU (1) HU226862B1 (ja)
LT (1) LT3398B (ja)
LV (1) LV10621B (ja)
MX (1) MX9305771A (ja)
NO (1) NO310413B1 (ja)
NZ (1) NZ256450A (ja)
PL (1) PL177316B1 (ja)
RU (1) RU2107065C1 (ja)
SK (1) SK280949B6 (ja)
TW (1) TW255890B (ja)
UA (1) UA44227C2 (ja)
WO (1) WO1994007882A1 (ja)
ZA (1) ZA937313B (ja)

Families Citing this family (74)

* Cited by examiner, † Cited by third party
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FR2696462B1 (fr) * 1992-10-05 1994-11-25 Rhone Poulenc Rorer Sa Procédé d'obtention de la désacétyl-10 baccatine III.
ATE420628T1 (de) 1993-07-19 2009-01-15 Angiotech Pharm Inc Anti-angiogene mittel und verfahren zu deren verwendung
WO1995012445A1 (de) * 1993-11-02 1995-05-11 Rhône-Poulenc Rorer GmbH Verfahren und vorrichtung zum auftrennen eines gemisches
FR2714053B1 (fr) * 1993-12-22 1996-03-08 Pf Medicament Procédé d'extraction et d'isolement de la 10-désacétylbaccatine III.
CN1112433A (zh) * 1994-05-24 1995-11-29 郭明 红豆杉属植物提取物及其应用
CA2178541C (en) 1995-06-07 2009-11-24 Neal E. Fearnot Implantable medical device
FR2736355B1 (fr) * 1995-07-07 1997-11-07 Pf Medicament Procede d'extraction et d'isolement de la 10-desacetylbaccatine iii
US5750736A (en) * 1996-07-11 1998-05-12 Napro Biotherapeutics, Inc. Method for acylating 10-deacetylbaccatin III selectively at the c-10 position
US5965752A (en) * 1996-08-23 1999-10-12 Institut National De La Recherche Scientifique Preparative scale isolation and purification of taxanes
DE69812395T2 (de) 1997-08-21 2004-02-05 Florida State University, Tallahassee Verfahren zur synthese von taxanen
US6002024A (en) * 1998-07-27 1999-12-14 Dabur Research Foundation Process for the isolation of 14β-hydroxy-10-deacetyl baccatin-III
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US6281368B1 (en) 2000-03-16 2001-08-28 Napro Biotherapeutics, Inc. Simple and efficient hydrazinolysis of C-10 and C-13 ester functionalities of taxanes to obtain 10-DAB III
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Family Cites Families (9)

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Publication number Priority date Publication date Assignee Title
FR2601675B1 (fr) * 1986-07-17 1988-09-23 Rhone Poulenc Sante Derives du taxol, leur preparation et les compositions pharmaceutiques qui les contiennent
FR2629818B1 (fr) 1988-04-06 1990-11-16 Centre Nat Rech Scient Procede de preparation du taxol
FR2629819B1 (fr) 1988-04-06 1990-11-16 Rhone Poulenc Sante Procede de preparation de derives de la baccatine iii et de la desacetyl-10 baccatine iii
US5175315A (en) 1989-05-31 1992-12-29 Florida State University Method for preparation of taxol using β-lactam
US5136060A (en) 1989-11-14 1992-08-04 Florida State University Method for preparation of taxol using an oxazinone
US5380916A (en) 1990-11-02 1995-01-10 University Of Florida Method for the isolation and purification of taxane derivatives
MX9102128A (es) 1990-11-23 1992-07-08 Rhone Poulenc Rorer Sa Derivados de taxano,procedimiento para su preparacion y composicion farmaceutica que los contiene
JP3222466B2 (ja) * 1991-04-19 2001-10-29 ザ・ユニバーシティ・オブ・ミシシッピー タクサン類を単離するための方法および組成物
IT1258838B (it) 1992-01-31 1996-02-29 Indena Spa Processo per l'estrazione di tassolo e derivati da cultivar del genere taxus

Also Published As

Publication number Publication date
UA44227C2 (uk) 2002-02-15
DE69308155D1 (de) 1997-03-27
CA2146373A1 (fr) 1994-04-14
AU680629B2 (en) 1997-08-07
GEP20001937B (en) 2000-02-05
ES2098061T3 (es) 1997-04-16
US5393895A (en) 1995-02-28
NO951282L (no) 1995-04-03
PL177316B1 (pl) 1999-10-29
CZ284615B6 (cs) 1999-01-13
GR3022617T3 (en) 1997-05-31
RU95110687A (ru) 1996-12-27
DE69308155T2 (de) 1997-08-07
FR2696463B1 (fr) 1994-11-25
MX9305771A (es) 1994-05-31
FI951596A0 (fi) 1995-04-04
JPH08501792A (ja) 1996-02-27
DK0663910T3 (da) 1997-03-10
NZ256450A (en) 1996-11-26
ATE148883T1 (de) 1997-02-15
PL308244A1 (en) 1995-07-24
KR950703550A (ko) 1995-09-20
NO951282D0 (no) 1995-04-03
SK43395A3 (en) 1995-08-09
TW255890B (ja) 1995-09-01
RU2107065C1 (ru) 1998-03-20
LTIP1397A (en) 1994-11-25
AU5115593A (en) 1994-04-26
HUT72449A (en) 1996-04-29
HU226862B1 (en) 2009-12-28
CA2146373C (fr) 2006-08-29
EP0663910A1 (fr) 1995-07-26
CZ84595A3 (en) 1995-09-13
LV10621B (en) 1995-10-20
CZ287065B6 (cs) 2000-08-16
CN1043530C (zh) 1999-06-02
EP0663910B1 (fr) 1997-02-12
LT3398B (en) 1995-09-25
ZA937313B (en) 1994-04-25
FI951596A (fi) 1995-04-04
EE03126B1 (et) 1998-10-15
WO1994007882A1 (fr) 1994-04-14
HU9500973D0 (en) 1995-06-28
KR100301236B1 (ko) 2001-11-22
LV10621A (lv) 1995-04-20
NO310413B1 (no) 2001-07-02
CN1085551A (zh) 1994-04-20
SK280949B6 (sk) 2000-09-12
JP3299754B2 (ja) 2002-07-08
FR2696463A1 (fr) 1994-04-08

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