PL3107899T3 - Policykliczne amidy wiążące mitochondrialną dehydrogenazę aldehydową-2 (aldh2) i ich zastosowanie w leczeniu nowotworów - Google Patents

Policykliczne amidy wiążące mitochondrialną dehydrogenazę aldehydową-2 (aldh2) i ich zastosowanie w leczeniu nowotworów

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Publication number
PL3107899T3
PL3107899T3 PL15711336T PL15711336T PL3107899T3 PL 3107899 T3 PL3107899 T3 PL 3107899T3 PL 15711336 T PL15711336 T PL 15711336T PL 15711336 T PL15711336 T PL 15711336T PL 3107899 T3 PL3107899 T3 PL 3107899T3
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PL
Poland
Prior art keywords
aldh2
cancer
treatment
aldehyde dehydrogenase
mitochondrial aldehyde
Prior art date
Application number
PL15711336T
Other languages
English (en)
Inventor
Wenjin Yang
Teh-Yie YU
Chun Jiang
Original Assignee
Aviv Therapeutics, Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Aviv Therapeutics, Inc. filed Critical Aviv Therapeutics, Inc.
Publication of PL3107899T3 publication Critical patent/PL3107899T3/pl

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    • C07D307/34—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D307/38—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms
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    • C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
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