EE03126B1 - Meetod 10-desatsetüülbakatiin III saamiseks ja 10-desatsetüülbakatiin III kasutamine - Google Patents
Meetod 10-desatsetüülbakatiin III saamiseks ja 10-desatsetüülbakatiin III kasutamineInfo
- Publication number
- EE03126B1 EE03126B1 EE9400364A EE9400364A EE03126B1 EE 03126 B1 EE03126 B1 EE 03126B1 EE 9400364 A EE9400364 A EE 9400364A EE 9400364 A EE9400364 A EE 9400364A EE 03126 B1 EE03126 B1 EE 03126B1
- Authority
- EE
- Estonia
- Prior art keywords
- deacetylbaccatin iii
- obtaining
- deacetylbaccatin
- iii
- taxus
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D305/00—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms
- C07D305/14—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms condensed with carbocyclic rings or ring systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Epoxy Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Plant Substances (AREA)
- Peptides Or Proteins (AREA)
- Saccharide Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Fats And Perfumes (AREA)
- Pyrane Compounds (AREA)
- Polyoxymethylene Polymers And Polymers With Carbon-To-Carbon Bonds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Separation Using Semi-Permeable Membranes (AREA)
- Compounds Of Unknown Constitution (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR9211746A FR2696463B1 (fr) | 1992-10-05 | 1992-10-05 | Procédé d'obtention de la désacétyl-10 baccatine III. |
Publications (1)
Publication Number | Publication Date |
---|---|
EE03126B1 true EE03126B1 (et) | 1998-10-15 |
Family
ID=9434124
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EE9400364A EE03126B1 (et) | 1992-10-05 | 1994-11-18 | Meetod 10-desatsetüülbakatiin III saamiseks ja 10-desatsetüülbakatiin III kasutamine |
Country Status (30)
Country | Link |
---|---|
US (1) | US5393895A (xx) |
EP (1) | EP0663910B1 (xx) |
JP (1) | JP3299754B2 (xx) |
KR (1) | KR100301236B1 (xx) |
CN (1) | CN1043530C (xx) |
AT (1) | ATE148883T1 (xx) |
AU (1) | AU680629B2 (xx) |
CA (1) | CA2146373C (xx) |
CZ (2) | CZ284615B6 (xx) |
DE (1) | DE69308155T2 (xx) |
DK (1) | DK0663910T3 (xx) |
EE (1) | EE03126B1 (xx) |
ES (1) | ES2098061T3 (xx) |
FI (1) | FI109794B (xx) |
FR (1) | FR2696463B1 (xx) |
GE (1) | GEP20001937B (xx) |
GR (1) | GR3022617T3 (xx) |
HU (1) | HU226862B1 (xx) |
LT (1) | LT3398B (xx) |
LV (1) | LV10621B (xx) |
MX (1) | MX9305771A (xx) |
NO (1) | NO310413B1 (xx) |
NZ (1) | NZ256450A (xx) |
PL (1) | PL177316B1 (xx) |
RU (1) | RU2107065C1 (xx) |
SK (1) | SK280949B6 (xx) |
TW (1) | TW255890B (xx) |
UA (1) | UA44227C2 (xx) |
WO (1) | WO1994007882A1 (xx) |
ZA (1) | ZA937313B (xx) |
Families Citing this family (74)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2696462B1 (fr) * | 1992-10-05 | 1994-11-25 | Rhone Poulenc Rorer Sa | Procédé d'obtention de la désacétyl-10 baccatine III. |
DE69435342D1 (de) | 1993-07-19 | 2011-05-05 | Angiotech Pharm Inc | Anti-Angiogene Mittel und Verfahren zu deren Verwendung |
ES2144533T3 (es) * | 1993-11-02 | 2000-06-16 | Rhone Poulenc Rorer Gmbh | Procedimiento para la separacion de una mezcla. |
FR2714053B1 (fr) * | 1993-12-22 | 1996-03-08 | Pf Medicament | Procédé d'extraction et d'isolement de la 10-désacétylbaccatine III. |
CN1112433A (zh) * | 1994-05-24 | 1995-11-29 | 郭明 | 红豆杉属植物提取物及其应用 |
CA2178541C (en) | 1995-06-07 | 2009-11-24 | Neal E. Fearnot | Implantable medical device |
FR2736355B1 (fr) * | 1995-07-07 | 1997-11-07 | Pf Medicament | Procede d'extraction et d'isolement de la 10-desacetylbaccatine iii |
US5750736A (en) * | 1996-07-11 | 1998-05-12 | Napro Biotherapeutics, Inc. | Method for acylating 10-deacetylbaccatin III selectively at the c-10 position |
US5965752A (en) * | 1996-08-23 | 1999-10-12 | Institut National De La Recherche Scientifique | Preparative scale isolation and purification of taxanes |
AU739303B2 (en) | 1997-08-21 | 2001-10-11 | Florida State University | Method for the synthesis of taxanes |
US6002024A (en) * | 1998-07-27 | 1999-12-14 | Dabur Research Foundation | Process for the isolation of 14β-hydroxy-10-deacetyl baccatin-III |
WO2002085337A1 (en) | 2001-04-20 | 2002-10-31 | The University Of British Columbia | Micellar drug delivery systems for hydrophobic drugs |
US6136989A (en) * | 1998-12-30 | 2000-10-24 | Phytogen Life Sciences, Incorporated | Method for high yield and large scale extraction of paclitaxel from paclitaxel-containing material |
US6281368B1 (en) | 2000-03-16 | 2001-08-28 | Napro Biotherapeutics, Inc. | Simple and efficient hydrazinolysis of C-10 and C-13 ester functionalities of taxanes to obtain 10-DAB III |
US6495705B2 (en) | 2000-03-16 | 2002-12-17 | Napro Biotherapeutics, Inc. | Efficient process for the production of 10-DAB III by selective hydrazinolysis of various taxanes |
CA2307393A1 (en) | 2000-05-01 | 2001-11-01 | The University Of British Columbia | Ginsenoside chemotherapy |
CA2440935A1 (en) | 2001-03-13 | 2002-09-19 | Richard Liggins | Micellar drug delivery vehicles and precursors thereto and uses thereof |
US20030157170A1 (en) * | 2001-03-13 | 2003-08-21 | Richard Liggins | Micellar drug delivery vehicles and precursors thereto and uses thereof |
US7351542B2 (en) | 2002-05-20 | 2008-04-01 | The Regents Of The University Of California | Methods of modulating tubulin deacetylase activity |
JP2006516548A (ja) | 2002-12-30 | 2006-07-06 | アンジオテック インターナショナル アクツィエン ゲゼルシャフト | 迅速ゲル化ポリマー組成物からの薬物送達法 |
US20070172446A1 (en) | 2003-05-16 | 2007-07-26 | Intermune, Inc. | Synthetic chemokine receptor ligands and methods of use thereof |
US7989490B2 (en) | 2004-06-02 | 2011-08-02 | Cordis Corporation | Injectable formulations of taxanes for cad treatment |
US7846940B2 (en) | 2004-03-31 | 2010-12-07 | Cordis Corporation | Solution formulations of sirolimus and its analogs for CAD treatment |
US8003122B2 (en) | 2004-03-31 | 2011-08-23 | Cordis Corporation | Device for local and/or regional delivery employing liquid formulations of therapeutic agents |
PL1778660T3 (pl) * | 2004-07-02 | 2009-07-31 | Ivax Pharmaceuticals Sro | Sposób rozdzielania paklitakselu i cefalomanniny |
US7597884B2 (en) | 2004-08-09 | 2009-10-06 | Alios Biopharma, Inc. | Hyperglycosylated polypeptide variants and methods of use |
WO2006089209A2 (en) | 2005-02-17 | 2006-08-24 | The Board Of Trustees Of The Leland Stanford Junior University | Txr1 and enhanced taxane sensitivity based on the modulation of a pathway mediated thereby |
WO2007062036A2 (en) | 2005-11-21 | 2007-05-31 | Med Institute, Inc. | Implantable medical device coatings with biodegradable elastomer and releasable therapeutic agent |
RU2448697C2 (ru) | 2006-03-22 | 2012-04-27 | Медигене Аг | Лечение рака молочной железы, негативного по трем рецепторам |
WO2008005284A2 (en) | 2006-06-30 | 2008-01-10 | Cook Incorporated | Methods of manufacturing and modifying taxane coatings for implantable medical devices |
US8409601B2 (en) | 2008-03-31 | 2013-04-02 | Cordis Corporation | Rapamycin coated expandable devices |
US8420110B2 (en) | 2008-03-31 | 2013-04-16 | Cordis Corporation | Drug coated expandable devices |
US8273404B2 (en) | 2008-05-19 | 2012-09-25 | Cordis Corporation | Extraction of solvents from drug containing polymer reservoirs |
WO2009143454A2 (en) | 2008-05-22 | 2009-11-26 | Kereos, Inc. | Combination antitumor therapy |
EP2310507A4 (en) | 2008-07-08 | 2013-03-20 | David Gladstone Inst | METHODS AND COMPOSITIONS FOR MODULATING ANGIOGENESIS |
US8642063B2 (en) | 2008-08-22 | 2014-02-04 | Cook Medical Technologies Llc | Implantable medical device coatings with biodegradable elastomer and releasable taxane agent |
US20120303115A1 (en) | 2011-05-25 | 2012-11-29 | Dadino Ronald C | Expandable devices coated with a rapamycin composition |
US20120302954A1 (en) | 2011-05-25 | 2012-11-29 | Zhao Jonathon Z | Expandable devices coated with a paclitaxel composition |
WO2013069027A1 (en) | 2011-09-26 | 2013-05-16 | Fresenius Kabi Oncology Ltd. | Processes for the preparation of cabazitaxel involving c(7) -oh and c(13) -oh silylation or just c(7) -oh silylation |
US9956385B2 (en) | 2012-06-28 | 2018-05-01 | The Spectranetics Corporation | Post-processing of a medical device to control morphology and mechanical properties |
EP3539563A1 (en) | 2012-07-19 | 2019-09-18 | Redwood Bioscience, Inc. | Antibody specific for cd22 and methods of use thereof |
AU2013341711A1 (en) | 2012-11-12 | 2015-05-21 | Redwood Bioscience, Inc. | Compounds and methods for producing a conjugate |
CN103804326A (zh) * | 2012-11-15 | 2014-05-21 | 刘胜远 | 一种从含10-去乙酰基巴卡亭ⅲ的浸膏分离和提纯10-去乙酰基巴卡亭ⅲ的方法 |
ES2758227T3 (es) | 2013-02-15 | 2020-05-04 | Univ California | Receptor de antígeno quimérico y métodos de uso del mismo |
CN103145652B (zh) * | 2013-03-05 | 2015-09-30 | 无锡尔云科技有限公司 | 一种从红豆杉属植物中提取紫杉醇及其衍生物的方法 |
JP6410790B2 (ja) | 2013-03-14 | 2018-10-24 | ザ ボード オブ トラスティーズ オブ ザ レランド スタンフォード ジュニア ユニバーシティー | ミトコンドリアアルデヒドデヒドロゲナーゼ−2調節因子およびその使用方法 |
CA2927806C (en) | 2013-11-27 | 2023-01-10 | Redwood Bioscience, Inc. | Hydrazinyl-pyrrolo compounds and methods for producing a conjugate |
US9879036B2 (en) | 2014-02-19 | 2018-01-30 | Aviv Therapeutics, Inc. | Mitochondrial aldehyde dehydrogenase-2 binding compounds and methods of use thereof |
CN108135917B (zh) | 2015-09-25 | 2021-07-09 | Zy医疗 | 基于包含多糖-维生素缀合物的颗粒的药物制剂 |
EP3373977A4 (en) | 2015-11-12 | 2019-07-17 | The Board of Trustees of the Leland Stanford Junior University | CELLULAR PENETRATION-RICH GUANIDINIC OLIGOPHOSPHOTRIESTERS FOR THE DELIVERY OF MEDICATION AND PROBE |
TWI760319B (zh) | 2015-12-30 | 2022-04-11 | 杏國新藥股份有限公司 | 乳癌治療 |
WO2017189432A1 (en) | 2016-04-26 | 2017-11-02 | R.P. Scherer Technologies, Llc | Antibody conjugates and methods of making and using the same |
MX2018014916A (es) | 2016-06-01 | 2019-07-18 | Servier Ip Uk Ltd | Formulaciones de oxido de polialquileno-asparaginasa y metodos de preparacion y uso del mismo. |
WO2018127082A1 (en) | 2017-01-05 | 2018-07-12 | Syncore Biotechnology Co., Ltd. | Treatment of pancreatic cancer |
BR112019014615A2 (pt) | 2017-01-18 | 2020-06-02 | F1 Oncology, Inc. | Receptores de antígeno quimérico contra axl ou ror2 e métodos de uso dos mesmos |
EP3388082A1 (en) | 2017-04-13 | 2018-10-17 | Galera Labs, LLC | Combination cancer immunotherapy with pentaaza macrocyclic ring complex |
EA202091832A1 (ru) | 2018-01-31 | 2021-01-11 | ГАЛЕРА ЛЭБЗ, ЭлЭлСи | Комбинированная терапия злокачественных новообразований макроциклическим кольцевым комплексом пентаазы и противоопухолевым агентом на основе платины |
US11660266B2 (en) | 2018-04-11 | 2023-05-30 | Ohio State Innovation Foundation | Methods and compositions for sustained release microparticles for ocular drug delivery |
CN108904137A (zh) * | 2018-05-27 | 2018-11-30 | 肖军威 | 一种卫生巾芯片的制备方法及卫生巾芯片的加工设备 |
MX2021000644A (es) | 2018-07-18 | 2021-08-19 | Manzanita Pharmaceuticals Inc | Conjugados para suministrar un agente contra el cancer a las celulas nerviosas, metodos de uso y metodos para la elaboracion de los mismos. |
WO2020148612A1 (en) | 2019-01-14 | 2020-07-23 | Ignite Immunotherapy, Inc. | Recombinant vaccinia virus and methods of use thereof |
US11685904B2 (en) | 2019-02-14 | 2023-06-27 | Ignite Immunotherapy, Inc. | Recombinant vaccinia virus and methods of use thereof |
EP3946626A1 (en) | 2019-04-02 | 2022-02-09 | Kenjockety Biotechnology, Inc. | Efflux pump-cancer antigen multi-specific antibodies and compositions, reagents, kits and methods related thereto |
CN110317183B (zh) * | 2019-08-08 | 2021-03-12 | 无锡紫杉药业有限公司 | 一种红豆杉天然提取产物的纯化方法 |
WO2021116943A1 (en) | 2019-12-12 | 2021-06-17 | Ignite Immunotherapy, Inc. | Variant oncolytic vaccinia virus and methods of use thereof |
MX2022009355A (es) | 2020-01-29 | 2022-09-02 | Kenjockety Biotechnology Inc | Anticuerpo anti-mdr1 y uso del mismo. |
US20230212305A1 (en) | 2020-06-04 | 2023-07-06 | Kenjockety Biotechnology, Inc. | Anti-abcg2 antibodies and uses thereof |
EP4161564A1 (en) | 2020-06-04 | 2023-04-12 | Kenjockety Biotechnology, Inc. | Abcg2 efflux pump-cancer antigen multi-specific antibodies and compositions, reagents, kits and methods related thereto |
EP4182335A2 (en) | 2020-07-14 | 2023-05-24 | Pfizer Inc. | Recombinant vaccinia virus |
CA3193588A1 (en) | 2020-09-02 | 2022-03-10 | Kenjockety Biotechnology, Inc. | Anti-abcc1 antibodies and uses thereof |
CA3203652A1 (en) | 2020-11-13 | 2022-05-19 | William Robert ARATHOON | Anti-mrp4 (encoded by abcc4 gene) antibodies and uses thereof |
CN112694458A (zh) * | 2020-12-29 | 2021-04-23 | 重庆臻源红豆杉发展有限公司 | 一种10-去乙酰基巴卡亭ⅲ提取纯化方法 |
AU2022413942A1 (en) | 2021-12-13 | 2024-05-30 | William Robert Arathoon Living Trust Dated August 29, 2016 | Anti-abcb1 antibodies |
WO2023159220A1 (en) | 2022-02-18 | 2023-08-24 | Kenjockety Biotechnology, Inc. | Anti-cd47 antibodies |
Family Cites Families (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2601675B1 (fr) * | 1986-07-17 | 1988-09-23 | Rhone Poulenc Sante | Derives du taxol, leur preparation et les compositions pharmaceutiques qui les contiennent |
FR2629819B1 (fr) | 1988-04-06 | 1990-11-16 | Rhone Poulenc Sante | Procede de preparation de derives de la baccatine iii et de la desacetyl-10 baccatine iii |
FR2629818B1 (fr) | 1988-04-06 | 1990-11-16 | Centre Nat Rech Scient | Procede de preparation du taxol |
US5175315A (en) | 1989-05-31 | 1992-12-29 | Florida State University | Method for preparation of taxol using β-lactam |
US5136060A (en) | 1989-11-14 | 1992-08-04 | Florida State University | Method for preparation of taxol using an oxazinone |
US5380916A (en) | 1990-11-02 | 1995-01-10 | University Of Florida | Method for the isolation and purification of taxane derivatives |
MX9102128A (es) | 1990-11-23 | 1992-07-08 | Rhone Poulenc Rorer Sa | Derivados de taxano,procedimiento para su preparacion y composicion farmaceutica que los contiene |
JP3222466B2 (ja) * | 1991-04-19 | 2001-10-29 | ザ・ユニバーシティ・オブ・ミシシッピー | タクサン類を単離するための方法および組成物 |
IT1258838B (it) | 1992-01-31 | 1996-02-29 | Indena Spa | Processo per l'estrazione di tassolo e derivati da cultivar del genere taxus |
-
1992
- 1992-10-05 FR FR9211746A patent/FR2696463B1/fr not_active Expired - Lifetime
-
1993
- 1993-01-27 US US08/010,083 patent/US5393895A/en not_active Expired - Lifetime
- 1993-04-10 UA UA95038244A patent/UA44227C2/uk unknown
- 1993-04-21 CN CN93104616A patent/CN1043530C/zh not_active Expired - Lifetime
- 1993-09-21 MX MX9305771A patent/MX9305771A/es unknown
- 1993-10-01 ZA ZA937313A patent/ZA937313B/xx unknown
- 1993-10-02 TW TW082108103A patent/TW255890B/zh not_active IP Right Cessation
- 1993-10-04 AT AT93921987T patent/ATE148883T1/de active
- 1993-10-04 CZ CZ95845A patent/CZ284615B6/cs not_active IP Right Cessation
- 1993-10-04 SK SK433-95A patent/SK280949B6/sk not_active IP Right Cessation
- 1993-10-04 AU AU51155/93A patent/AU680629B2/en not_active Expired
- 1993-10-04 KR KR1019950701306A patent/KR100301236B1/ko not_active IP Right Cessation
- 1993-10-04 HU HU9500973A patent/HU226862B1/hu unknown
- 1993-10-04 RU RU95110687/04A patent/RU2107065C1/ru active
- 1993-10-04 EP EP93921987A patent/EP0663910B1/fr not_active Expired - Lifetime
- 1993-10-04 PL PL93308244A patent/PL177316B1/pl unknown
- 1993-10-04 CA CA002146373A patent/CA2146373C/fr not_active Expired - Lifetime
- 1993-10-04 ES ES93921987T patent/ES2098061T3/es not_active Expired - Lifetime
- 1993-10-04 DE DE69308155T patent/DE69308155T2/de not_active Expired - Lifetime
- 1993-10-04 LT LTIP1397A patent/LT3398B/lt not_active IP Right Cessation
- 1993-10-04 JP JP50879294A patent/JP3299754B2/ja not_active Expired - Lifetime
- 1993-10-04 NZ NZ256450A patent/NZ256450A/en not_active IP Right Cessation
- 1993-10-04 GE GEAP19932511A patent/GEP20001937B/en unknown
- 1993-10-04 WO PCT/FR1993/000972 patent/WO1994007882A1/fr active IP Right Grant
- 1993-10-04 DK DK93921987.9T patent/DK0663910T3/da active
- 1993-10-04 LV LVP-93-1120A patent/LV10621B/xx unknown
-
1994
- 1994-11-18 EE EE9400364A patent/EE03126B1/xx unknown
-
1995
- 1995-04-03 NO NO19951282A patent/NO310413B1/no not_active IP Right Cessation
- 1995-04-04 FI FI951596A patent/FI109794B/fi not_active IP Right Cessation
-
1997
- 1997-02-20 GR GR960402767T patent/GR3022617T3/el unknown
-
1998
- 1998-02-06 CZ CZ1998367A patent/CZ287065B6/cs not_active IP Right Cessation
Also Published As
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Publication | Publication Date | Title |
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EE03126B1 (et) | Meetod 10-desatsetüülbakatiin III saamiseks ja 10-desatsetüülbakatiin III kasutamine | |
EE03124B1 (et) | Meetod 10-desatsetüülbakatiin III saamiseks ja 10-desatsetüülbakatiin III kasutamine | |
DK0553780T3 (da) | Fremgangsmåde til ekstraktion af taxol og derivater deraf fra planter tilhørende taxus-slægten | |
DK0863887T3 (da) | Mellemprodukter til hemisyntese af taxaner og fremgangsmåder til deres fremstilling | |
DE69615562D1 (de) | Verfahren zu extrahieren und isolierung von 10-desacetylbachatin iii |
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