FI108637B - Menetelmä lääkeaineena käyttökelpoisen (+)-(S)-2-(3-bentsoyylifenyyli)propaanihapon trometamiinisuolan valmistamiseksi - Google Patents

Menetelmä lääkeaineena käyttökelpoisen (+)-(S)-2-(3-bentsoyylifenyyli)propaanihapon trometamiinisuolan valmistamiseksi Download PDF

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Publication number
FI108637B
FI108637B FI952230A FI952230A FI108637B FI 108637 B FI108637 B FI 108637B FI 952230 A FI952230 A FI 952230A FI 952230 A FI952230 A FI 952230A FI 108637 B FI108637 B FI 108637B
Authority
FI
Finland
Prior art keywords
ketoprofen
salt
benzoylphenyl
propanoic acid
compound
Prior art date
Application number
FI952230A
Other languages
English (en)
Finnish (fi)
Swedish (sv)
Other versions
FI952230A0 (fi
FI952230A (fi
Inventor
Germano Garganico
Casellas David Mauleon
Perez M Luisa Garcia
Original Assignee
Menarini Lab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Menarini Lab filed Critical Menarini Lab
Publication of FI952230A0 publication Critical patent/FI952230A0/fi
Publication of FI952230A publication Critical patent/FI952230A/fi
Application granted granted Critical
Publication of FI108637B publication Critical patent/FI108637B/fi

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C215/00—Compounds containing amino and hydroxy groups bound to the same carbon skeleton
    • C07C215/02—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton
    • C07C215/04—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being saturated
    • C07C215/06—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being saturated and acyclic
    • C07C215/10—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being saturated and acyclic with one amino group and at least two hydroxy groups bound to the carbon skeleton
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C59/40—Unsaturated compounds
    • C07C59/76—Unsaturated compounds containing keto groups
    • C07C59/84—Unsaturated compounds containing keto groups containing six membered aromatic rings

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Neurology (AREA)
  • Pain & Pain Management (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Rheumatology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
FI952230A 1992-11-10 1995-05-09 Menetelmä lääkeaineena käyttökelpoisen (+)-(S)-2-(3-bentsoyylifenyyli)propaanihapon trometamiinisuolan valmistamiseksi FI108637B (fi)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
ES9202260 1992-11-10
ES09202260A ES2058024B1 (es) 1992-11-10 1992-11-10 Nuevo derivado arilpropionico, procedimiento de fabricacion del mismo y su utilizacion como analgesico.
PCT/EP1993/003127 WO1994011332A1 (en) 1992-11-10 1993-11-09 A novel arylpropionic derivative, a process for the preparation and the use thereof as an analgesic agent
EP9303127 1993-11-09

Publications (3)

Publication Number Publication Date
FI952230A0 FI952230A0 (fi) 1995-05-09
FI952230A FI952230A (fi) 1995-05-09
FI108637B true FI108637B (fi) 2002-02-28

Family

ID=8278730

Family Applications (1)

Application Number Title Priority Date Filing Date
FI952230A FI108637B (fi) 1992-11-10 1995-05-09 Menetelmä lääkeaineena käyttökelpoisen (+)-(S)-2-(3-bentsoyylifenyyli)propaanihapon trometamiinisuolan valmistamiseksi

Country Status (27)

Country Link
US (1) US5554789A (es)
EP (1) EP0668851B1 (es)
JP (1) JP3778516B2 (es)
KR (1) KR100284838B1 (es)
AT (1) ATE153649T1 (es)
AU (1) AU674040B2 (es)
BG (1) BG61723B1 (es)
BR (1) BR9307408A (es)
CA (1) CA2149013C (es)
CZ (1) CZ286621B6 (es)
DE (2) DE668851T1 (es)
DK (1) DK0668851T3 (es)
ES (2) ES2058024B1 (es)
FI (1) FI108637B (es)
GR (2) GR960300012T1 (es)
HK (1) HK1006306A1 (es)
HU (2) HU217973B (es)
MD (1) MD921G2 (es)
NO (2) NO304306B1 (es)
NZ (1) NZ257557A (es)
PL (1) PL175265B1 (es)
RO (1) RO118712B1 (es)
RU (1) RU2128160C1 (es)
SK (1) SK280550B6 (es)
UA (1) UA44233C2 (es)
UY (1) UY24179A1 (es)
WO (1) WO1994011332A1 (es)

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ATE445838T1 (de) 2001-07-25 2009-10-15 Raptor Pharmaceutical Inc Zusammensetzungen und verfahren zur modulation des transports durch die blut-hirn-schranke
US20080051411A1 (en) * 2002-12-17 2008-02-28 Cink Russell D Salts of Fenofibric Acid and Pharmaceutical Formulations Thereof
WO2004054568A1 (en) * 2002-12-17 2004-07-01 Abbott Gmbh & Co. Kg Formulation comprising fenofibric acid, a physiologically acceptable salt or derivative thereof
EP2671508B1 (en) 2005-04-28 2020-09-16 Proteus Digital Health, Inc. Pharma-informatics system
EP1739072A1 (en) * 2005-06-15 2007-01-03 Laboratorios Menarini S.A. Polymorphic forms of dexketoprofen trometamol, preparation and pharmaceutical compositions thereof
CA2663377A1 (en) 2006-09-18 2008-03-27 Raptor Pharmaceutical Inc. Treatment of liver disorders by administration of receptor-associated protein (rap)-conjugates
TWI364413B (en) * 2008-07-25 2012-05-21 Univ Nat Central Racemic ibuprofen amine salt and synthesis method thereof
JP5628816B2 (ja) * 2008-10-31 2014-11-19 ツェー・アー・イー・エルバイオサイエンスシーズ、ゲーエムベーハー リコフェロンのコリンおよびトロメタミン塩
HUE059078T2 (hu) 2009-02-20 2022-10-28 Enhanx Biopharm Inc Glutation-alapú hatóanyagszállító rendszer
JP2012526144A (ja) 2009-05-06 2012-10-25 ラボラトリー スキン ケア インコーポレイテッド 活性物質−リン酸カルシウム粒子複合体を含む経皮送達組成物およびその使用方法
ES2350670B1 (es) * 2009-06-10 2011-12-07 Polichem, S.L. Composicion veterinaria de ketoprofeno
CN101928214B (zh) * 2009-06-19 2012-12-19 黄石世星药业有限责任公司 右旋酮洛芬氨丁三醇的一种合成方法
WO2011001213A1 (en) * 2009-06-30 2011-01-06 Abdi Ibrahim Ilac Sanayi Ve Ticaret Anonim Sirketi A process for preparing dexketoprofen trometamol form a and form b crystals
US20120077778A1 (en) 2010-09-29 2012-03-29 Andrea Bourdelais Ladder-Frame Polyether Conjugates
CN102557976B (zh) * 2010-12-15 2015-06-10 辽宁盛京制药有限公司 溴芬酸有机盐及其制备方法、其组合物及用途
TR201104864A2 (tr) 2011-05-18 2012-12-21 Bi̇lgi̇ç Mahmut Deksketoprofen içeren suda çözünebilir formülasyonlar.
TR201205317A2 (tr) 2011-05-18 2012-12-21 B�Lg�� Mahmut Deksketoprofen içeren efervesan formülasyonlar.
CN102381986A (zh) * 2011-07-25 2012-03-21 南京特丰药业股份有限公司 一种右旋布洛芬氨丁三醇盐及其口服溶液的制备方法
WO2013022410A2 (en) * 2011-08-08 2013-02-14 Mahmut Bilgic Production method for effervescent formulations comprising dexketoprofen
WO2013095315A1 (en) 2011-12-19 2013-06-27 Mahmut Bilgic Formulations comprising dexketoprofen (particle size 300-2500 micrometer)
WO2013100877A1 (en) 2011-12-27 2013-07-04 Mahmut Bilgic Dexketoprofen formulations
EP2671569B1 (en) 2012-06-06 2015-09-16 Galenicum Health S.L. Stable pharmaceutical compositions with fast onset
EP2759293A1 (en) 2013-01-25 2014-07-30 Laboratorios Lesvi, S.L. Pharmaceutical compositions of (+)-(s)-2-(3-benzoylphenyl)propionic acid tromethamine salt
ES2512497T1 (es) 2013-02-06 2014-10-24 Galenicum Health S.L. Proceso para preparar una composición farmacéutica estable que comprende dexketoprofeno trometamol
ITMI20130210A1 (it) 2013-02-14 2014-08-15 Menarini Lab Composizioni farmaceutiche contenenti dexketoprofene e tramadolo
TR201616365A1 (tr) 2016-11-14 2018-05-21 Sanovel Ilac Sanayi Ve Ticaret Anonim Sirketi Deksketoprofen ve eletri̇ptanin oral farmasöti̇k kompozi̇syonlari
AU2017364349A1 (en) 2016-11-28 2019-07-11 Sarin PARAYIL Novel organic crystalline salt of haloacetic acid
TR201618765A2 (tr) 2016-12-16 2018-07-23 Imuneks Farma Ilac Sanayi Ve Ticaret Anonim Sirketi Ağrı ve enflamasyonun tedavisi için steroid olmayan anti-enflamatuvar ilaçlar ve H2 reseptörü antagonisti kombinasyonları.
KR102462607B1 (ko) * 2020-11-11 2022-11-03 대원제약주식회사 펠루비프로펜 신규 염을 주성분으로 하는 안정성이 증가된 약학적 조성물
KR102552315B1 (ko) * 2020-11-11 2023-07-06 대원제약주식회사 펠루비프로펜 신규 염을 주성분으로 하며 위장장애 부작용이 저감된 약학적 조성물
KR20230140540A (ko) * 2022-03-25 2023-10-06 일동제약(주) Glp-1 수용체 작용제 화합물의 신규 염, 이의 제조방법 및 이를 포함하는 약학 조성물

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Also Published As

Publication number Publication date
PL175265B1 (pl) 1998-12-31
HUT71903A (en) 1996-02-28
ES2058024A1 (es) 1994-10-16
NO304306B1 (no) 1998-11-30
KR100284838B1 (ko) 2001-04-02
GR960300012T1 (en) 1996-03-31
US5554789A (en) 1996-09-10
GR3024344T3 (en) 1997-10-31
ES2081780T3 (es) 1997-07-01
HK1006306A1 (en) 1999-02-19
SK280550B6 (sk) 2000-03-13
BG99609A (bg) 1996-01-31
HU9802850D0 (en) 1999-02-01
EP0668851A1 (en) 1995-08-30
ATE153649T1 (de) 1997-06-15
JP3778516B2 (ja) 2006-05-24
FI952230A0 (fi) 1995-05-09
HU9501375D0 (en) 1995-06-28
DE69311130T2 (de) 1997-09-18
BR9307408A (pt) 1999-08-24
FI952230A (fi) 1995-05-09
PL308466A1 (en) 1995-07-24
CA2149013C (en) 2004-08-10
HU219975B (hu) 2001-10-28
NO2006007I1 (no) 2006-08-14
ES2081780T1 (es) 1996-03-16
UY24179A1 (es) 1996-09-03
NZ257557A (en) 1996-01-26
JPH08503203A (ja) 1996-04-09
EP0668851B1 (en) 1997-05-28
DE69311130D1 (de) 1997-07-03
MD921G2 (ro) 1998-10-31
SK60395A3 (en) 1995-09-13
CZ286621B6 (cs) 2000-05-17
DE668851T1 (de) 1996-10-10
DK0668851T3 (da) 1997-12-22
CA2149013A1 (en) 1994-05-26
AU674040B2 (en) 1996-12-05
BG61723B1 (bg) 1998-04-30
RO118712B1 (ro) 2003-09-30
RU95112575A (ru) 1997-06-20
RU2128160C1 (ru) 1999-03-27
AU5421094A (en) 1994-06-08
HU217973B (hu) 2000-05-28
ES2058024B1 (es) 1995-05-01
WO1994011332A1 (en) 1994-05-26
NO951790L (no) 1995-07-06
NO951790D0 (no) 1995-05-08
UA44233C2 (uk) 2002-02-15
CZ114995A3 (en) 1995-10-18

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