FI952230A0 - Uusi aryylipropaanijohdannainen, menetelmä sen valmistamiseksi ja sen käyttö analgeettisena aineena - Google Patents

Uusi aryylipropaanijohdannainen, menetelmä sen valmistamiseksi ja sen käyttö analgeettisena aineena

Info

Publication number
FI952230A0
FI952230A0 FI952230A FI952230A FI952230A0 FI 952230 A0 FI952230 A0 FI 952230A0 FI 952230 A FI952230 A FI 952230A FI 952230 A FI952230 A FI 952230A FI 952230 A0 FI952230 A0 FI 952230A0
Authority
FI
Finland
Prior art keywords
preparation
derivative
arylpropane
new
pct
Prior art date
Application number
FI952230A
Other languages
English (en)
Swedish (sv)
Other versions
FI952230A (fi
FI108637B (fi
Inventor
Germano Garganico
Casellas David Mauleon
Perez M Luisa Garcia
Original Assignee
Menarini Lab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Menarini Lab filed Critical Menarini Lab
Publication of FI952230A publication Critical patent/FI952230A/fi
Publication of FI952230A0 publication Critical patent/FI952230A0/fi
Application granted granted Critical
Publication of FI108637B publication Critical patent/FI108637B/fi

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C215/00—Compounds containing amino and hydroxy groups bound to the same carbon skeleton
    • C07C215/02—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton
    • C07C215/04—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being saturated
    • C07C215/06—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being saturated and acyclic
    • C07C215/10—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being saturated and acyclic with one amino group and at least two hydroxy groups bound to the carbon skeleton
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C59/40—Unsaturated compounds
    • C07C59/76—Unsaturated compounds containing keto groups
    • C07C59/84—Unsaturated compounds containing keto groups containing six membered aromatic rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Neurology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
FI952230A 1992-11-10 1995-05-09 Menetelmä lääkeaineena käyttökelpoisen (+)-(S)-2-(3-bentsoyylifenyyli)propaanihapon trometamiinisuolan valmistamiseksi FI108637B (fi)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
ES9202260 1992-11-10
ES09202260A ES2058024B1 (es) 1992-11-10 1992-11-10 Nuevo derivado arilpropionico, procedimiento de fabricacion del mismo y su utilizacion como analgesico.
EP9303127 1993-11-09
PCT/EP1993/003127 WO1994011332A1 (en) 1992-11-10 1993-11-09 A novel arylpropionic derivative, a process for the preparation and the use thereof as an analgesic agent

Publications (3)

Publication Number Publication Date
FI952230A FI952230A (fi) 1995-05-09
FI952230A0 true FI952230A0 (fi) 1995-05-09
FI108637B FI108637B (fi) 2002-02-28

Family

ID=8278730

Family Applications (1)

Application Number Title Priority Date Filing Date
FI952230A FI108637B (fi) 1992-11-10 1995-05-09 Menetelmä lääkeaineena käyttökelpoisen (+)-(S)-2-(3-bentsoyylifenyyli)propaanihapon trometamiinisuolan valmistamiseksi

Country Status (27)

Country Link
US (1) US5554789A (fi)
EP (1) EP0668851B1 (fi)
JP (1) JP3778516B2 (fi)
KR (1) KR100284838B1 (fi)
AT (1) ATE153649T1 (fi)
AU (1) AU674040B2 (fi)
BG (1) BG61723B1 (fi)
BR (1) BR9307408A (fi)
CA (1) CA2149013C (fi)
CZ (1) CZ286621B6 (fi)
DE (2) DE668851T1 (fi)
DK (1) DK0668851T3 (fi)
ES (2) ES2058024B1 (fi)
FI (1) FI108637B (fi)
GR (2) GR960300012T1 (fi)
HK (1) HK1006306A1 (fi)
HU (2) HU219975B (fi)
MD (1) MD921G2 (fi)
NO (2) NO304306B1 (fi)
NZ (1) NZ257557A (fi)
PL (1) PL175265B1 (fi)
RO (1) RO118712B1 (fi)
RU (1) RU2128160C1 (fi)
SK (1) SK280550B6 (fi)
UA (1) UA44233C2 (fi)
UY (1) UY24179A1 (fi)
WO (1) WO1994011332A1 (fi)

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ES2124196B1 (es) * 1997-06-04 1999-12-01 Menarini Lab Procedimiento para la fabricacion de una forma farmaceutica semisolida conteniendo dexketoprofeno trometamol y su utilizacion en el tratamiento topico de la inflamacion.
EP2147679B1 (en) 2001-07-25 2014-06-25 Raptor Pharmaceutical, Inc. Compositions for blood-brain barrier transport
DE60313359T2 (de) * 2002-12-17 2008-01-03 Abbott Gmbh & Co. Kg Fenofibratsäure enthaltende pharmazeutische zusammensetzung und deren physiologisch verträgliche salze und derivate
US20080051411A1 (en) * 2002-12-17 2008-02-28 Cink Russell D Salts of Fenofibric Acid and Pharmaceutical Formulations Thereof
DK1889198T3 (da) 2005-04-28 2015-02-09 Proteus Digital Health Inc Farma-informatiksystem
EP1739072A1 (en) * 2005-06-15 2007-01-03 Laboratorios Menarini S.A. Polymorphic forms of dexketoprofen trometamol, preparation and pharmaceutical compositions thereof
WO2008036682A2 (en) 2006-09-18 2008-03-27 Raptor Pharmaceutical Inc. Treatment of liver disorders by administration of receptor-associated protein (rap)-conjugates
TWI364413B (en) * 2008-07-25 2012-05-21 Univ Nat Central Racemic ibuprofen amine salt and synthesis method thereof
US8519155B2 (en) * 2008-10-31 2013-08-27 C-A-I-R Biosciences Gmbh Choline and tromethamine salt of licofelone
DK2398500T3 (da) 2009-02-20 2019-05-13 2 Bbb Medicines B V Glutathion-baseret lægemiddelafgivelsessystem
IL255113B (en) 2009-05-06 2022-09-01 Laboratory Skin Care Inc Preparations for administration through the skin that include complexes of an active substance with calcium phosphate and methods of using them
ES2350670B1 (es) * 2009-06-10 2011-12-07 Polichem, S.L. Composicion veterinaria de ketoprofeno
CN101928214B (zh) * 2009-06-19 2012-12-19 黄石世星药业有限责任公司 右旋酮洛芬氨丁三醇的一种合成方法
WO2011001213A1 (en) * 2009-06-30 2011-01-06 Abdi Ibrahim Ilac Sanayi Ve Ticaret Anonim Sirketi A process for preparing dexketoprofen trometamol form a and form b crystals
US20120077778A1 (en) 2010-09-29 2012-03-29 Andrea Bourdelais Ladder-Frame Polyether Conjugates
CN102557976B (zh) * 2010-12-15 2015-06-10 辽宁盛京制药有限公司 溴芬酸有机盐及其制备方法、其组合物及用途
TR201205317A2 (tr) 2011-05-18 2012-12-21 B�Lg�� Mahmut Deksketoprofen içeren efervesan formülasyonlar.
TR201104864A2 (tr) 2011-05-18 2012-12-21 Bi̇lgi̇ç Mahmut Deksketoprofen içeren suda çözünebilir formülasyonlar.
CN102381986A (zh) * 2011-07-25 2012-03-21 南京特丰药业股份有限公司 一种右旋布洛芬氨丁三醇盐及其口服溶液的制备方法
WO2013022410A2 (en) 2011-08-08 2013-02-14 Mahmut Bilgic Production method for effervescent formulations comprising dexketoprofen
WO2013095315A1 (en) 2011-12-19 2013-06-27 Mahmut Bilgic Formulations comprising dexketoprofen (particle size 300-2500 micrometer)
WO2013100877A1 (en) 2011-12-27 2013-07-04 Mahmut Bilgic Dexketoprofen formulations
EP2671569B1 (en) 2012-06-06 2015-09-16 Galenicum Health S.L. Stable pharmaceutical compositions with fast onset
EP2759293A1 (en) 2013-01-25 2014-07-30 Laboratorios Lesvi, S.L. Pharmaceutical compositions of (+)-(s)-2-(3-benzoylphenyl)propionic acid tromethamine salt
EP2764875A1 (en) 2013-02-06 2014-08-13 Galenicum Health S.L. Process for preparing a stable pharmaceutical composition comprising dexketoprofen trometamol
ITMI20130210A1 (it) 2013-02-14 2014-08-15 Menarini Lab Composizioni farmaceutiche contenenti dexketoprofene e tramadolo
TR201616365A1 (tr) 2016-11-14 2018-05-21 Sanovel Ilac Sanayi Ve Ticaret Anonim Sirketi Deksketoprofen ve eletri̇ptanin oral farmasöti̇k kompozi̇syonlari
AU2017364349A1 (en) * 2016-11-28 2019-07-11 Sarin PARAYIL Novel organic crystalline salt of haloacetic acid
TR201618765A2 (tr) 2016-12-16 2018-07-23 Imuneks Farma Ilac Sanayi Ve Ticaret Anonim Sirketi Ağrı ve enflamasyonun tedavisi için steroid olmayan anti-enflamatuvar ilaçlar ve H2 reseptörü antagonisti kombinasyonları.
KR102462607B1 (ko) * 2020-11-11 2022-11-03 대원제약주식회사 펠루비프로펜 신규 염을 주성분으로 하는 안정성이 증가된 약학적 조성물
KR102552315B1 (ko) * 2020-11-11 2023-07-06 대원제약주식회사 펠루비프로펜 신규 염을 주성분으로 하며 위장장애 부작용이 저감된 약학적 조성물
TW202345815A (zh) * 2022-03-25 2023-12-01 南韓商日東製藥股份有限公司 Glp-1受體激動劑化合物之新穎鹽類、其製備方法以及包含其之醫藥組合物

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FR2319340A1 (fr) * 1975-07-28 1977-02-25 Roussel Uclaf Nouveau sel de l'acide a-methyl benzoyl-5 thiophene-2 acetique, procede de preparation et application a titre de medicament
ES455698A1 (es) * 1977-02-07 1978-01-01 Invest Tecnica Aplicada Procedimiento para la preparacion de un nuevo derivado buta-nolaminico.
GR68102B (fi) * 1978-08-08 1981-10-30 Fujisawa Pharmaceutical Co
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CH664563A5 (it) * 1985-04-19 1988-03-15 Seuref Ag Composti con attivita antiflogistica, antipiretica, analgesica, loro preparazione e composizioni farmaceutiche che li contengono.
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Also Published As

Publication number Publication date
RU2128160C1 (ru) 1999-03-27
JPH08503203A (ja) 1996-04-09
FI952230A (fi) 1995-05-09
CZ114995A3 (en) 1995-10-18
MD921G2 (ro) 1998-10-31
HU219975B (hu) 2001-10-28
FI108637B (fi) 2002-02-28
ES2058024A1 (es) 1994-10-16
NO2006007I1 (no) 2006-08-14
ES2058024B1 (es) 1995-05-01
AU5421094A (en) 1994-06-08
ES2081780T1 (es) 1996-03-16
HK1006306A1 (en) 1999-02-19
UA44233C2 (uk) 2002-02-15
SK60395A3 (en) 1995-09-13
DK0668851T3 (da) 1997-12-22
NO951790D0 (no) 1995-05-08
HU217973B (hu) 2000-05-28
PL308466A1 (en) 1995-07-24
HUT71903A (en) 1996-02-28
NZ257557A (en) 1996-01-26
HU9802850D0 (en) 1999-02-01
PL175265B1 (pl) 1998-12-31
DE69311130D1 (de) 1997-07-03
RO118712B1 (ro) 2003-09-30
EP0668851B1 (en) 1997-05-28
BR9307408A (pt) 1999-08-24
ES2081780T3 (es) 1997-07-01
US5554789A (en) 1996-09-10
WO1994011332A1 (en) 1994-05-26
DE668851T1 (de) 1996-10-10
AU674040B2 (en) 1996-12-05
ATE153649T1 (de) 1997-06-15
CA2149013A1 (en) 1994-05-26
BG61723B1 (bg) 1998-04-30
SK280550B6 (sk) 2000-03-13
HU9501375D0 (en) 1995-06-28
CA2149013C (en) 2004-08-10
BG99609A (bg) 1996-01-31
JP3778516B2 (ja) 2006-05-24
CZ286621B6 (cs) 2000-05-17
GR960300012T1 (en) 1996-03-31
NO951790L (no) 1995-07-06
GR3024344T3 (en) 1997-10-31
KR100284838B1 (ko) 2001-04-02
RU95112575A (ru) 1997-06-20
NO304306B1 (no) 1998-11-30
EP0668851A1 (en) 1995-08-30
DE69311130T2 (de) 1997-09-18
UY24179A1 (es) 1996-09-03

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Legal Events

Date Code Title Description
MA Patent expired