GR960300012T1 - A novel arylpropionic derivative, a process for the preparation and the use thereof as an analgesic agent. - Google Patents

A novel arylpropionic derivative, a process for the preparation and the use thereof as an analgesic agent.

Info

Publication number
GR960300012T1
GR960300012T1 GR960300012T GR960300012T GR960300012T1 GR 960300012 T1 GR960300012 T1 GR 960300012T1 GR 960300012 T GR960300012 T GR 960300012T GR 960300012 T GR960300012 T GR 960300012T GR 960300012 T1 GR960300012 T1 GR 960300012T1
Authority
GR
Greece
Prior art keywords
preparation
pct
analgesic agent
derivative
novel
Prior art date
Application number
GR960300012T
Other languages
English (en)
Inventor
Germano Carganico
Casellas David Mauleon
Perez M Luisa Garcia
Original Assignee
Menarini Lab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Menarini Lab filed Critical Menarini Lab
Publication of GR960300012T1 publication Critical patent/GR960300012T1/el

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C215/00Compounds containing amino and hydroxy groups bound to the same carbon skeleton
    • C07C215/02Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton
    • C07C215/04Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being saturated
    • C07C215/06Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being saturated and acyclic
    • C07C215/10Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being saturated and acyclic with one amino group and at least two hydroxy groups bound to the carbon skeleton
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00Drugs for disorders of the muscular or neuromuscular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/04Centrally acting analgesics, e.g. opioids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C59/00Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C59/40Unsaturated compounds
    • C07C59/76Unsaturated compounds containing keto groups
    • C07C59/84Unsaturated compounds containing keto groups containing six membered aromatic rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Neurology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
GR960300012T 1992-11-10 1996-03-31 A novel arylpropionic derivative, a process for the preparation and the use thereof as an analgesic agent. GR960300012T1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
ES09202260A ES2058024B1 (es) 1992-11-10 1992-11-10 Nuevo derivado arilpropionico, procedimiento de fabricacion del mismo y su utilizacion como analgesico.
PCT/EP1993/003127 WO1994011332A1 (en) 1992-11-10 1993-11-09 A novel arylpropionic derivative, a process for the preparation and the use thereof as an analgesic agent

Publications (1)

Publication Number Publication Date
GR960300012T1 true GR960300012T1 (en) 1996-03-31

Family

ID=8278730

Family Applications (2)

Application Number Title Priority Date Filing Date
GR960300012T GR960300012T1 (en) 1992-11-10 1996-03-31 A novel arylpropionic derivative, a process for the preparation and the use thereof as an analgesic agent.
GR970401991T GR3024344T3 (en) 1992-11-10 1997-07-31 A novel arylpropionic derivative, a process for the preparation and the use thereof as an analgesic agent.

Family Applications After (1)

Application Number Title Priority Date Filing Date
GR970401991T GR3024344T3 (en) 1992-11-10 1997-07-31 A novel arylpropionic derivative, a process for the preparation and the use thereof as an analgesic agent.

Country Status (27)

Country Link
US (1) US5554789A (el)
EP (1) EP0668851B1 (el)
JP (1) JP3778516B2 (el)
KR (1) KR100284838B1 (el)
AT (1) ATE153649T1 (el)
AU (1) AU674040B2 (el)
BG (1) BG61723B1 (el)
BR (1) BR9307408A (el)
CA (1) CA2149013C (el)
CZ (1) CZ286621B6 (el)
DE (2) DE69311130T2 (el)
DK (1) DK0668851T3 (el)
ES (2) ES2058024B1 (el)
FI (1) FI108637B (el)
GR (2) GR960300012T1 (el)
HK (1) HK1006306A1 (el)
HU (2) HU219975B (el)
MD (1) MD921G2 (el)
NO (2) NO304306B1 (el)
NZ (1) NZ257557A (el)
PL (1) PL175265B1 (el)
RO (1) RO118712B1 (el)
RU (1) RU2128160C1 (el)
SK (1) SK280550B6 (el)
UA (1) UA44233C2 (el)
UY (1) UY24179A1 (el)
WO (1) WO1994011332A1 (el)

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US20030129186A1 (en) 2001-07-25 2003-07-10 Biomarin Pharmaceutical Inc. Compositions and methods for modulating blood-brain barrier transport
US20080051411A1 (en) * 2002-12-17 2008-02-28 Cink Russell D Salts of Fenofibric Acid and Pharmaceutical Formulations Thereof
DE60313359T2 (de) * 2002-12-17 2008-01-03 Abbott Gmbh & Co. Kg Fenofibratsäure enthaltende pharmazeutische zusammensetzung und deren physiologisch verträgliche salze und derivate
PT1889198E (pt) 2005-04-28 2015-03-06 Proteus Digital Health Inc Sistema fármaco-informático
EP1739072A1 (en) * 2005-06-15 2007-01-03 Laboratorios Menarini S.A. Polymorphic forms of dexketoprofen trometamol, preparation and pharmaceutical compositions thereof
WO2008036682A2 (en) 2006-09-18 2008-03-27 Raptor Pharmaceutical Inc. Treatment of liver disorders by administration of receptor-associated protein (rap)-conjugates
TWI364413B (en) * 2008-07-25 2012-05-21 Univ Nat Central Racemic ibuprofen amine salt and synthesis method thereof
CN102264741B (zh) * 2008-10-31 2014-07-16 C-A-I-R生物科学有限公司 利考非隆的胆碱盐
PT2398500T (pt) 2009-02-20 2019-06-14 2 Bbb Medicines B V Sistema de entrega de medicamentos à base de glutationas
ES2942923T3 (es) 2009-05-06 2023-06-07 Laboratory Skin Care Inc Composiciones de administración dérmica que comprenden complejos de agente activo-partículas de fosfato de calcio y métodos de uso de las mismas
ES2350670B1 (es) * 2009-06-10 2011-12-07 Polichem, S.L. Composicion veterinaria de ketoprofeno
CN101928214B (zh) * 2009-06-19 2012-12-19 黄石世星药业有限责任公司 右旋酮洛芬氨丁三醇的一种合成方法
WO2011001213A1 (en) * 2009-06-30 2011-01-06 Abdi Ibrahim Ilac Sanayi Ve Ticaret Anonim Sirketi A process for preparing dexketoprofen trometamol form a and form b crystals
US20120077778A1 (en) 2010-09-29 2012-03-29 Andrea Bourdelais Ladder-Frame Polyether Conjugates
CN102557976B (zh) * 2010-12-15 2015-06-10 辽宁盛京制药有限公司 溴芬酸有机盐及其制备方法、其组合物及用途
TR201104864A2 (tr) 2011-05-18 2012-12-21 Bi̇lgi̇ç Mahmut Deksketoprofen içeren suda çözünebilir formülasyonlar.
TR201205317A2 (tr) 2011-05-18 2012-12-21 B�Lg�� Mahmut Deksketoprofen içeren efervesan formülasyonlar.
CN102381986A (zh) * 2011-07-25 2012-03-21 南京特丰药业股份有限公司 一种右旋布洛芬氨丁三醇盐及其口服溶液的制备方法
WO2013022410A2 (en) * 2011-08-08 2013-02-14 Mahmut Bilgic Production method for effervescent formulations comprising dexketoprofen
WO2013095315A1 (en) 2011-12-19 2013-06-27 Mahmut Bilgic Formulations comprising dexketoprofen (particle size 300-2500 micrometer)
WO2013100877A1 (en) 2011-12-27 2013-07-04 Mahmut Bilgic Dexketoprofen formulations
EP2671569B1 (en) 2012-06-06 2015-09-16 Galenicum Health S.L. Stable pharmaceutical compositions with fast onset
EP2759293A1 (en) 2013-01-25 2014-07-30 Laboratorios Lesvi, S.L. Pharmaceutical compositions of (+)-(s)-2-(3-benzoylphenyl)propionic acid tromethamine salt
ES2512497T1 (es) 2013-02-06 2014-10-24 Galenicum Health S.L. Proceso para preparar una composición farmacéutica estable que comprende dexketoprofeno trometamol
ITMI20130210A1 (it) 2013-02-14 2014-08-15 Menarini Lab Composizioni farmaceutiche contenenti dexketoprofene e tramadolo
TR201616365A1 (tr) 2016-11-14 2018-05-21 Sanovel Ilac Sanayi Ve Ticaret Anonim Sirketi Deksketoprofen ve eletri̇ptanin oral farmasöti̇k kompozi̇syonlari
AU2017364349A1 (en) 2016-11-28 2019-07-11 Sarin PARAYIL Novel organic crystalline salt of haloacetic acid
TR201618765A2 (tr) 2016-12-16 2018-07-23 Imuneks Farma Ilac Sanayi Ve Ticaret Anonim Sirketi Ağrı ve enflamasyonun tedavisi için steroid olmayan anti-enflamatuvar ilaçlar ve H2 reseptörü antagonisti kombinasyonları.
KR102552315B1 (ko) * 2020-11-11 2023-07-06 대원제약주식회사 펠루비프로펜 신규 염을 주성분으로 하며 위장장애 부작용이 저감된 약학적 조성물
KR102462607B1 (ko) * 2020-11-11 2022-11-03 대원제약주식회사 펠루비프로펜 신규 염을 주성분으로 하는 안정성이 증가된 약학적 조성물
WO2023182869A1 (en) * 2022-03-25 2023-09-28 Ildong Pharmaceutical Co., Ltd. Novel salt of glp-1 receptor agonist compound, preparation method thereof and pharmaceutical composition comprising thereof

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FR1201726A (fr) * 1959-06-20 1960-01-05 Procédé d'obtention de dérivés flavoniques à partir des feuilles de certains végétaux
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BR6915470D0 (pt) * 1969-03-24 1973-03-13 Syntex Corp Processo para preparar derivados de acido 2-(6'substituido 2'naftil)propionico e de seus sais
GB1408853A (en) * 1972-03-17 1975-10-08 Upjohn Co Medical process and treatment
US3821289A (en) * 1972-07-03 1974-06-28 Rorer Inc William H Tetrahydronaphthylalkanoic acids and their derivatives
GB1497044A (en) * 1974-03-07 1978-01-05 Prodotti Antibiotici Spa Salts of phenyl-alkanoic acids
US4097674A (en) * 1975-03-17 1978-06-27 Syntex Corporation 2-Naphthylacetic acid derivatives
FR2319340A1 (fr) * 1975-07-28 1977-02-25 Roussel Uclaf Nouveau sel de l'acide a-methyl benzoyl-5 thiophene-2 acetique, procede de preparation et application a titre de medicament
ES455698A1 (es) * 1977-02-07 1978-01-01 Invest Tecnica Aplicada Procedimiento para la preparacion de un nuevo derivado buta-nolaminico.
GR68102B (el) * 1978-08-08 1981-10-30 Fujisawa Pharmaceutical Co
HU185926B (en) * 1979-09-27 1985-04-28 Agostne Kahan Process for preparing water soluble derivatives of non-steroid antiinflammatory compositions and pharmaceutical compositins containing such derivatives
DE3328401A1 (de) * 1983-08-05 1985-02-21 Merckle GmbH, 7902 Blaubeuren Injizierbare loesung zur behandlung von entzuendungen
CH664563A5 (it) * 1985-04-19 1988-03-15 Seuref Ag Composti con attivita antiflogistica, antipiretica, analgesica, loro preparazione e composizioni farmaceutiche che li contengono.
IL81049A0 (en) * 1985-12-20 1987-03-31 Wisconsin Alumni Res Found Preparation of(s)-alpha-methylarylacetic acids
IT1207994B (it) * 1986-01-03 1989-06-01 Therapicon Srl Sali idrosulubili di composti adattivita' antiinfiammatoria ed analgesica, loro preparazione ed utilizzo in composizioni farmaceutiche.
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Also Published As

Publication number Publication date
BG61723B1 (bg) 1998-04-30
CA2149013C (en) 2004-08-10
AU674040B2 (en) 1996-12-05
ES2058024B1 (es) 1995-05-01
RU2128160C1 (ru) 1999-03-27
ES2058024A1 (es) 1994-10-16
ATE153649T1 (de) 1997-06-15
HUT71903A (en) 1996-02-28
EP0668851A1 (en) 1995-08-30
HU9501375D0 (en) 1995-06-28
JPH08503203A (ja) 1996-04-09
CZ286621B6 (cs) 2000-05-17
FI108637B (fi) 2002-02-28
ES2081780T1 (es) 1996-03-16
UY24179A1 (es) 1996-09-03
PL308466A1 (en) 1995-07-24
RU95112575A (ru) 1997-06-20
UA44233C2 (uk) 2002-02-15
MD921G2 (ro) 1998-10-31
HU217973B (hu) 2000-05-28
HU9802850D0 (en) 1999-02-01
DE668851T1 (de) 1996-10-10
SK280550B6 (sk) 2000-03-13
RO118712B1 (ro) 2003-09-30
DE69311130D1 (de) 1997-07-03
ES2081780T3 (es) 1997-07-01
NO304306B1 (no) 1998-11-30
AU5421094A (en) 1994-06-08
CA2149013A1 (en) 1994-05-26
WO1994011332A1 (en) 1994-05-26
HK1006306A1 (en) 1999-02-19
BR9307408A (pt) 1999-08-24
CZ114995A3 (en) 1995-10-18
NO2006007I1 (no) 2006-08-14
NO951790L (no) 1995-07-06
BG99609A (bg) 1996-01-31
FI952230A (fi) 1995-05-09
NO951790D0 (no) 1995-05-08
GR3024344T3 (en) 1997-10-31
FI952230A0 (fi) 1995-05-09
DE69311130T2 (de) 1997-09-18
SK60395A3 (en) 1995-09-13
HU219975B (hu) 2001-10-28
JP3778516B2 (ja) 2006-05-24
PL175265B1 (pl) 1998-12-31
NZ257557A (en) 1996-01-26
DK0668851T3 (da) 1997-12-22
EP0668851B1 (en) 1997-05-28
US5554789A (en) 1996-09-10
KR100284838B1 (ko) 2001-04-02

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