NO2006007I1 - (+)-(S)-2-(3-benzoylfenyl)-propionsyre-trometaminsalt(deksketoprofentrometamol) - Google Patents

(+)-(S)-2-(3-benzoylfenyl)-propionsyre-trometaminsalt(deksketoprofentrometamol)

Info

Publication number
NO2006007I1
NO2006007I1 NO2006007C NO2006007C NO2006007I1 NO 2006007 I1 NO2006007 I1 NO 2006007I1 NO 2006007 C NO2006007 C NO 2006007C NO 2006007 C NO2006007 C NO 2006007C NO 2006007 I1 NO2006007 I1 NO 2006007I1
Authority
NO
Norway
Prior art keywords
benzoylphenyl
propionic acid
deksketoprofentrometamol
pct
tromethamine salt
Prior art date
Application number
NO2006007C
Other languages
English (en)
Original Assignee
Menarini Lab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Menarini Lab filed Critical Menarini Lab
Publication of NO2006007I1 publication Critical patent/NO2006007I1/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C215/00—Compounds containing amino and hydroxy groups bound to the same carbon skeleton
    • C07C215/02—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton
    • C07C215/04—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being saturated
    • C07C215/06—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being saturated and acyclic
    • C07C215/10—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being saturated and acyclic with one amino group and at least two hydroxy groups bound to the carbon skeleton
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C59/40—Unsaturated compounds
    • C07C59/76—Unsaturated compounds containing keto groups
    • C07C59/84—Unsaturated compounds containing keto groups containing six membered aromatic rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Neurology (AREA)
  • Pain & Pain Management (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Rheumatology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
NO2006007C 1992-11-10 2006-07-31 (+)-(S)-2-(3-benzoylfenyl)-propionsyre-trometaminsalt(deksketoprofentrometamol) NO2006007I1 (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
ES09202260A ES2058024B1 (es) 1992-11-10 1992-11-10 Nuevo derivado arilpropionico, procedimiento de fabricacion del mismo y su utilizacion como analgesico.
PCT/EP1993/003127 WO1994011332A1 (en) 1992-11-10 1993-11-09 A novel arylpropionic derivative, a process for the preparation and the use thereof as an analgesic agent

Publications (1)

Publication Number Publication Date
NO2006007I1 true NO2006007I1 (no) 2006-08-14

Family

ID=8278730

Family Applications (2)

Application Number Title Priority Date Filing Date
NO951790A NO304306B1 (no) 1992-11-10 1995-05-08 Nytt arylpropionsyrederivat, farmas°ytisk blanding inneholdende dette, og anvendelse av det nye derivat ved fremstilling av et medikament
NO2006007C NO2006007I1 (no) 1992-11-10 2006-07-31 (+)-(S)-2-(3-benzoylfenyl)-propionsyre-trometaminsalt(deksketoprofentrometamol)

Family Applications Before (1)

Application Number Title Priority Date Filing Date
NO951790A NO304306B1 (no) 1992-11-10 1995-05-08 Nytt arylpropionsyrederivat, farmas°ytisk blanding inneholdende dette, og anvendelse av det nye derivat ved fremstilling av et medikament

Country Status (27)

Country Link
US (1) US5554789A (no)
EP (1) EP0668851B1 (no)
JP (1) JP3778516B2 (no)
KR (1) KR100284838B1 (no)
AT (1) ATE153649T1 (no)
AU (1) AU674040B2 (no)
BG (1) BG61723B1 (no)
BR (1) BR9307408A (no)
CA (1) CA2149013C (no)
CZ (1) CZ286621B6 (no)
DE (2) DE668851T1 (no)
DK (1) DK0668851T3 (no)
ES (2) ES2058024B1 (no)
FI (1) FI108637B (no)
GR (2) GR960300012T1 (no)
HK (1) HK1006306A1 (no)
HU (2) HU219975B (no)
MD (1) MD921G2 (no)
NO (2) NO304306B1 (no)
NZ (1) NZ257557A (no)
PL (1) PL175265B1 (no)
RO (1) RO118712B1 (no)
RU (1) RU2128160C1 (no)
SK (1) SK280550B6 (no)
UA (1) UA44233C2 (no)
UY (1) UY24179A1 (no)
WO (1) WO1994011332A1 (no)

Families Citing this family (32)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2124196B1 (es) * 1997-06-04 1999-12-01 Menarini Lab Procedimiento para la fabricacion de una forma farmaceutica semisolida conteniendo dexketoprofeno trometamol y su utilizacion en el tratamiento topico de la inflamacion.
DE60234057D1 (de) 2001-07-25 2009-11-26 Raptor Pharmaceutical Inc Zusammensetzungen und verfahren zur modulation des transports durch die blut-hirn-schranke
US20080051411A1 (en) * 2002-12-17 2008-02-28 Cink Russell D Salts of Fenofibric Acid and Pharmaceutical Formulations Thereof
CN101480384A (zh) * 2002-12-17 2009-07-15 阿伯特有限及两合公司 包含非诺贝酸、其生理可接受的盐或衍生物的制剂
EP2392258B1 (en) 2005-04-28 2014-10-08 Proteus Digital Health, Inc. Pharma-informatics system
EP1739072A1 (en) * 2005-06-15 2007-01-03 Laboratorios Menarini S.A. Polymorphic forms of dexketoprofen trometamol, preparation and pharmaceutical compositions thereof
US8795627B2 (en) 2007-03-21 2014-08-05 Raptor Pharmaceuticals Inc. Treatment of liver disorders by administration of RAP conjugates
TWI364413B (en) * 2008-07-25 2012-05-21 Univ Nat Central Racemic ibuprofen amine salt and synthesis method thereof
WO2010049525A1 (en) * 2008-10-31 2010-05-06 C-A-I-R Biosciences Gmbh Choline and tromethamine salt of licofelone
AU2010216512B2 (en) 2009-02-20 2016-06-30 2-Bbb Medicines B.V. Glutathione-based drug delivery system
WO2010129819A2 (en) 2009-05-06 2010-11-11 Laboratory Skin Care, Inc. Dermal delivery compositions comprising active agent-calcium phosphate particle complexes and methods of using the same
ES2350670B1 (es) * 2009-06-10 2011-12-07 Polichem, S.L. Composicion veterinaria de ketoprofeno
CN101928214B (zh) * 2009-06-19 2012-12-19 黄石世星药业有限责任公司 右旋酮洛芬氨丁三醇的一种合成方法
EP2475636A1 (en) * 2009-06-30 2012-07-18 Abdi Ibrahim Ilac Sanayi ve Ticaret Anonim Sirketi A process for preparing dexketoprofen trometamol form a and form b crystals
US20120077778A1 (en) 2010-09-29 2012-03-29 Andrea Bourdelais Ladder-Frame Polyether Conjugates
CN102557976B (zh) * 2010-12-15 2015-06-10 辽宁盛京制药有限公司 溴芬酸有机盐及其制备方法、其组合物及用途
TR201205317A2 (tr) 2011-05-18 2012-12-21 B�Lg�� Mahmut Deksketoprofen içeren efervesan formülasyonlar.
TR201104864A2 (tr) 2011-05-18 2012-12-21 Bi̇lgi̇ç Mahmut Deksketoprofen içeren suda çözünebilir formülasyonlar.
CN102381986A (zh) * 2011-07-25 2012-03-21 南京特丰药业股份有限公司 一种右旋布洛芬氨丁三醇盐及其口服溶液的制备方法
WO2013022410A2 (en) 2011-08-08 2013-02-14 Mahmut Bilgic Production method for effervescent formulations comprising dexketoprofen
WO2013095315A1 (en) 2011-12-19 2013-06-27 Mahmut Bilgic Formulations comprising dexketoprofen (particle size 300-2500 micrometer)
WO2013100877A1 (en) 2011-12-27 2013-07-04 Mahmut Bilgic Dexketoprofen formulations
ES2501415T3 (es) 2012-06-06 2016-02-22 Galenicum Health S.L. Composiciones farmacéuticas estables de acción rápida
EP2759293A1 (en) 2013-01-25 2014-07-30 Laboratorios Lesvi, S.L. Pharmaceutical compositions of (+)-(s)-2-(3-benzoylphenyl)propionic acid tromethamine salt
EP2764875A1 (en) 2013-02-06 2014-08-13 Galenicum Health S.L. Process for preparing a stable pharmaceutical composition comprising dexketoprofen trometamol
ITMI20130210A1 (it) 2013-02-14 2014-08-15 Menarini Lab Composizioni farmaceutiche contenenti dexketoprofene e tramadolo
TR201616365A1 (tr) 2016-11-14 2018-05-21 Sanovel Ilac Sanayi Ve Ticaret Anonim Sirketi Deksketoprofen ve eletri̇ptanin oral farmasöti̇k kompozi̇syonlari
WO2018096517A1 (en) * 2016-11-28 2018-05-31 Parayil Sarin Novel organic crystalline salt of haloacetic acid
TR201618765A2 (tr) 2016-12-16 2018-07-23 Imuneks Farma Ilac Sanayi Ve Ticaret Anonim Sirketi Ağrı ve enflamasyonun tedavisi için steroid olmayan anti-enflamatuvar ilaçlar ve H2 reseptörü antagonisti kombinasyonları.
KR102552315B1 (ko) * 2020-11-11 2023-07-06 대원제약주식회사 펠루비프로펜 신규 염을 주성분으로 하며 위장장애 부작용이 저감된 약학적 조성물
KR102462607B1 (ko) * 2020-11-11 2022-11-03 대원제약주식회사 펠루비프로펜 신규 염을 주성분으로 하는 안정성이 증가된 약학적 조성물
WO2023182869A1 (en) * 2022-03-25 2023-09-28 Ildong Pharmaceutical Co., Ltd. Novel salt of glp-1 receptor agonist compound, preparation method thereof and pharmaceutical composition comprising thereof

Family Cites Families (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US427996A (en) * 1890-05-13 houg-hton
FR1201726A (fr) * 1959-06-20 1960-01-05 Procédé d'obtention de dérivés flavoniques à partir des feuilles de certains végétaux
FR1546478A (fr) * 1967-01-27 1968-11-22 Rhone Poulenc Sa Nouveaux dérivés de l'acide benzoyl-3 phénylacétique et leur préparation
BR6915470D0 (pt) * 1969-03-24 1973-03-13 Syntex Corp Processo para preparar derivados de acido 2-(6'substituido 2'naftil)propionico e de seus sais
GB1408853A (en) * 1972-03-17 1975-10-08 Upjohn Co Medical process and treatment
US3821289A (en) * 1972-07-03 1974-06-28 Rorer Inc William H Tetrahydronaphthylalkanoic acids and their derivatives
GB1497044A (en) * 1974-03-07 1978-01-05 Prodotti Antibiotici Spa Salts of phenyl-alkanoic acids
US4097674A (en) * 1975-03-17 1978-06-27 Syntex Corporation 2-Naphthylacetic acid derivatives
FR2319340A1 (fr) * 1975-07-28 1977-02-25 Roussel Uclaf Nouveau sel de l'acide a-methyl benzoyl-5 thiophene-2 acetique, procede de preparation et application a titre de medicament
ES455698A1 (es) * 1977-02-07 1978-01-01 Invest Tecnica Aplicada Procedimiento para la preparacion de un nuevo derivado buta-nolaminico.
GR68102B (no) * 1978-08-08 1981-10-30 Fujisawa Pharmaceutical Co
HU185926B (en) * 1979-09-27 1985-04-28 Agostne Kahan Process for preparing water soluble derivatives of non-steroid antiinflammatory compositions and pharmaceutical compositins containing such derivatives
DE3328401A1 (de) * 1983-08-05 1985-02-21 Merckle GmbH, 7902 Blaubeuren Injizierbare loesung zur behandlung von entzuendungen
CH664563A5 (it) * 1985-04-19 1988-03-15 Seuref Ag Composti con attivita antiflogistica, antipiretica, analgesica, loro preparazione e composizioni farmaceutiche che li contengono.
DK620486A (da) * 1985-12-20 1987-06-21 Wisconsin Alumni Res Found Fremgangsmaade til fremstilling af eddikesyrederivater
IT1207994B (it) * 1986-01-03 1989-06-01 Therapicon Srl Sali idrosulubili di composti adattivita' antiinfiammatoria ed analgesica, loro preparazione ed utilizzo in composizioni farmaceutiche.
US4960892A (en) * 1988-06-10 1990-10-02 American Home Products Corporation Naphthalenepropionic acid derivatives as anti-inflammatory/anti-allergic agents
US4868214A (en) * 1987-11-17 1989-09-19 Analgesic Associates Onset-hastened/enhanced analgesia
JPH02502534A (ja) * 1987-12-18 1990-08-16 チバ‐ガイギー　アクチェンゲゼルシャフト １‐メチル‐β‐オキソ‐α‐（フェニルカルバモイル）‐２‐ピロールプロピオニトリルのトロメタミン塩

Also Published As

Publication number Publication date
HK1006306A1 (en) 1999-02-19
FI952230A0 (fi) 1995-05-09
BR9307408A (pt) 1999-08-24
ES2058024A1 (es) 1994-10-16
ES2081780T3 (es) 1997-07-01
NO951790D0 (no) 1995-05-08
HU219975B (hu) 2001-10-28
ES2081780T1 (es) 1996-03-16
MD921G2 (ro) 1998-10-31
BG99609A (bg) 1996-01-31
EP0668851B1 (en) 1997-05-28
JPH08503203A (ja) 1996-04-09
US5554789A (en) 1996-09-10
WO1994011332A1 (en) 1994-05-26
RO118712B1 (ro) 2003-09-30
AU5421094A (en) 1994-06-08
UA44233C2 (uk) 2002-02-15
PL308466A1 (en) 1995-07-24
NZ257557A (en) 1996-01-26
GR3024344T3 (en) 1997-10-31
CZ286621B6 (cs) 2000-05-17
NO304306B1 (no) 1998-11-30
AU674040B2 (en) 1996-12-05
HU217973B (hu) 2000-05-28
ATE153649T1 (de) 1997-06-15
PL175265B1 (pl) 1998-12-31
FI108637B (fi) 2002-02-28
RU95112575A (ru) 1997-06-20
DE69311130D1 (de) 1997-07-03
CA2149013A1 (en) 1994-05-26
DE668851T1 (de) 1996-10-10
FI952230A (fi) 1995-05-09
HU9501375D0 (en) 1995-06-28
SK280550B6 (sk) 2000-03-13
JP3778516B2 (ja) 2006-05-24
KR100284838B1 (ko) 2001-04-02
GR960300012T1 (en) 1996-03-31
UY24179A1 (es) 1996-09-03
NO951790L (no) 1995-07-06
EP0668851A1 (en) 1995-08-30
ES2058024B1 (es) 1995-05-01
DK0668851T3 (da) 1997-12-22
DE69311130T2 (de) 1997-09-18
BG61723B1 (bg) 1998-04-30
CZ114995A3 (en) 1995-10-18
SK60395A3 (en) 1995-09-13
HUT71903A (en) 1996-02-28
CA2149013C (en) 2004-08-10
RU2128160C1 (ru) 1999-03-27
HU9802850D0 (en) 1999-02-01

Similar Documents

Publication Publication Date Title
NO2006007I1 (no) (+)-(S)-2-(3-benzoylfenyl)-propionsyre-trometaminsalt(deksketoprofentrometamol)
MA23170A1 (fr) Procede de preparation d'un nouveau compose .
NO308794B1 (no) Farmakologisk aktive pyridin-derivater, preparater inneholdende forbindelsene samt forbindelsenes anvendelse
AU3202595A (en) 1,2-substituted imidazolyl compounds for the treatment of inflammation
AR042345A2 (es) Un procedimiento para la preparacion de una composicion farmaceutica para el tratamiento de aterosclerosis que contiene 8.9 - dehidroesterona o sus sales de la misma
DE69415018D1 (de) Oralanzuwendende flüssige arzneizubereitung enthaltend 2-(4-isobutylphenyl)propionsäure
HUP0004780A2 (hu) Prosztaglandin agonisták felhasználása merevedési rendellenességek vagy impotencia kezelésében
BR9507231A (pt) Uso de derivados de ácido carboxílico para a produção de drogas
ATE212024T1 (de) Morphin- und diamorphinsalze anionischer nicht- narkotischer analgetika vom typ der substituierten carbonsäuren
DK0627916T3 (da) Farmaceutisk præparat, anvendeligt som analgetikum og indeholdende (R)-2-(3-benzoylphenyl)propionsyre
AU7470098A (en) Antithrombotic agents
ATE173471T1 (de) Pyridazinonderivate oder deren salze, verfahren zu ihrer herstellung und diese enthaltende antischockmittel
AU6519596A (en) Use of allylamine derivatives such as terbinafine, in the manufacture of a medicament for the treatment of helicobacter pylori infection of associated diseases
SE9401596D0 (sv) New compounds
PT100098A (pt) Novos sais do acido 2-(2,6-dicloroanilino)-fenilacetico, processo para a sua preparacao e sua utilizacao em composicoes farmaceuticas para aplicacao topica
FI952855A (fi) Uudet triatsolokinatsoliinit, niiden valmistus ja käyttö
AU7274198A (en) Antithrombotic agents
AU5269696A (en) Anellated beta-carbolines