UY24179A1 - Procedimiento para la obtención de la sal de trometamina del acido (+)-(s)-2-(3-benzoilfenil)-propionico - Google Patents

Procedimiento para la obtención de la sal de trometamina del acido (+)-(s)-2-(3-benzoilfenil)-propionico

Info

Publication number
UY24179A1
UY24179A1 UY24179A UY24179A UY24179A1 UY 24179 A1 UY24179 A1 UY 24179A1 UY 24179 A UY24179 A UY 24179A UY 24179 A UY24179 A UY 24179A UY 24179 A1 UY24179 A1 UY 24179A1
Authority
UY
Uruguay
Prior art keywords
propionic acid
benzoylphenil
procedure
obtaining
pct
Prior art date
Application number
UY24179A
Other languages
English (en)
Inventor
Carganico Germano
Mauleon Casellas David
Luisa Garcia Perez Marias
Original Assignee
Laboratorios Menarini S A
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Laboratorios Menarini S A filed Critical Laboratorios Menarini S A
Publication of UY24179A1 publication Critical patent/UY24179A1/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C215/00—Compounds containing amino and hydroxy groups bound to the same carbon skeleton
    • C07C215/02—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton
    • C07C215/04—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being saturated
    • C07C215/06—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being saturated and acyclic
    • C07C215/10—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being saturated and acyclic with one amino group and at least two hydroxy groups bound to the carbon skeleton
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C59/40—Unsaturated compounds
    • C07C59/76—Unsaturated compounds containing keto groups
    • C07C59/84—Unsaturated compounds containing keto groups containing six membered aromatic rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Neurology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)

Abstract

La presente invención se refiere a un procedimiento para la obtención de la sal de trometamina del ácido (+)-(S)-2-(3-benzoilfenil)-propiónico (fig. 1), caracterizado por hacer reaccionar el ácido (+)-(S)-2-(3-benzoilfenil)propiónico con la trometamina en cantidades equimolares. Dicho compuesto posee propiedades analgésicas.
UY24179A 1992-11-10 1996-03-14 Procedimiento para la obtención de la sal de trometamina del acido (+)-(s)-2-(3-benzoilfenil)-propionico UY24179A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ES09202260A ES2058024B1 (es) 1992-11-10 1992-11-10 Nuevo derivado arilpropionico, procedimiento de fabricacion del mismo y su utilizacion como analgesico.

Publications (1)

Publication Number Publication Date
UY24179A1 true UY24179A1 (es) 1996-09-03

Family

ID=8278730

Family Applications (1)

Application Number Title Priority Date Filing Date
UY24179A UY24179A1 (es) 1992-11-10 1996-03-14 Procedimiento para la obtención de la sal de trometamina del acido (+)-(s)-2-(3-benzoilfenil)-propionico

Country Status (27)

Country Link
US (1) US5554789A (es)
EP (1) EP0668851B1 (es)
JP (1) JP3778516B2 (es)
KR (1) KR100284838B1 (es)
AT (1) ATE153649T1 (es)
AU (1) AU674040B2 (es)
BG (1) BG61723B1 (es)
BR (1) BR9307408A (es)
CA (1) CA2149013C (es)
CZ (1) CZ286621B6 (es)
DE (2) DE69311130T2 (es)
DK (1) DK0668851T3 (es)
ES (2) ES2058024B1 (es)
FI (1) FI108637B (es)
GR (2) GR960300012T1 (es)
HK (1) HK1006306A1 (es)
HU (2) HU217973B (es)
MD (1) MD921G2 (es)
NO (2) NO304306B1 (es)
NZ (1) NZ257557A (es)
PL (1) PL175265B1 (es)
RO (1) RO118712B1 (es)
RU (1) RU2128160C1 (es)
SK (1) SK280550B6 (es)
UA (1) UA44233C2 (es)
UY (1) UY24179A1 (es)
WO (1) WO1994011332A1 (es)

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ES2124196B1 (es) * 1997-06-04 1999-12-01 Menarini Lab Procedimiento para la fabricacion de una forma farmaceutica semisolida conteniendo dexketoprofeno trometamol y su utilizacion en el tratamiento topico de la inflamacion.
ATE445838T1 (de) 2001-07-25 2009-10-15 Raptor Pharmaceutical Inc Zusammensetzungen und verfahren zur modulation des transports durch die blut-hirn-schranke
CN100473378C (zh) * 2002-12-17 2009-04-01 阿伯特有限及两合公司 包含非诺贝酸、其生理可接受的盐或衍生物的制剂
US20080051411A1 (en) * 2002-12-17 2008-02-28 Cink Russell D Salts of Fenofibric Acid and Pharmaceutical Formulations Thereof
DK1889198T3 (da) 2005-04-28 2015-02-09 Proteus Digital Health Inc Farma-informatiksystem
EP1739072A1 (en) * 2005-06-15 2007-01-03 Laboratorios Menarini S.A. Polymorphic forms of dexketoprofen trometamol, preparation and pharmaceutical compositions thereof
WO2008036682A2 (en) 2006-09-18 2008-03-27 Raptor Pharmaceutical Inc. Treatment of liver disorders by administration of receptor-associated protein (rap)-conjugates
TWI364413B (en) * 2008-07-25 2012-05-21 Univ Nat Central Racemic ibuprofen amine salt and synthesis method thereof
NZ592378A (en) * 2008-10-31 2012-09-28 C A I R Biosciences Gmbh Choline and tromethamine salt of licofelone
ES2728225T3 (es) 2009-02-20 2019-10-23 2 Bbb Medicines B V Sistema de administración de fármacos a base de glutatión
US8445002B2 (en) 2009-05-06 2013-05-21 Laboratory Skin Care, Inc. Dermal delivery compositions comprising active agent-calcium phosphate particle complexes and methods of using the same
ES2350670B1 (es) * 2009-06-10 2011-12-07 Polichem, S.L. Composicion veterinaria de ketoprofeno
CN101928214B (zh) * 2009-06-19 2012-12-19 黄石世星药业有限责任公司 右旋酮洛芬氨丁三醇的一种合成方法
EP2475636A1 (en) * 2009-06-30 2012-07-18 Abdi Ibrahim Ilac Sanayi ve Ticaret Anonim Sirketi A process for preparing dexketoprofen trometamol form a and form b crystals
US20120077778A1 (en) 2010-09-29 2012-03-29 Andrea Bourdelais Ladder-Frame Polyether Conjugates
CN102557976B (zh) * 2010-12-15 2015-06-10 辽宁盛京制药有限公司 溴芬酸有机盐及其制备方法、其组合物及用途
TR201104864A2 (tr) 2011-05-18 2012-12-21 Bi̇lgi̇ç Mahmut Deksketoprofen içeren suda çözünebilir formülasyonlar.
TR201205317A2 (tr) 2011-05-18 2012-12-21 B�Lg�� Mahmut Deksketoprofen içeren efervesan formülasyonlar.
CN102381986A (zh) * 2011-07-25 2012-03-21 南京特丰药业股份有限公司 一种右旋布洛芬氨丁三醇盐及其口服溶液的制备方法
WO2013022410A2 (en) * 2011-08-08 2013-02-14 Mahmut Bilgic Production method for effervescent formulations comprising dexketoprofen
WO2013095315A1 (en) 2011-12-19 2013-06-27 Mahmut Bilgic Formulations comprising dexketoprofen (particle size 300-2500 micrometer)
WO2013100877A1 (en) 2011-12-27 2013-07-04 Mahmut Bilgic Dexketoprofen formulations
EP2671569B1 (en) 2012-06-06 2015-09-16 Galenicum Health S.L. Stable pharmaceutical compositions with fast onset
EP2759293A1 (en) 2013-01-25 2014-07-30 Laboratorios Lesvi, S.L. Pharmaceutical compositions of (+)-(s)-2-(3-benzoylphenyl)propionic acid tromethamine salt
EP2764875A1 (en) 2013-02-06 2014-08-13 Galenicum Health S.L. Process for preparing a stable pharmaceutical composition comprising dexketoprofen trometamol
ITMI20130210A1 (it) 2013-02-14 2014-08-15 Menarini Lab Composizioni farmaceutiche contenenti dexketoprofene e tramadolo
TR201616365A1 (tr) 2016-11-14 2018-05-21 Sanovel Ilac Sanayi Ve Ticaret Anonim Sirketi Deksketoprofen ve eletri̇ptanin oral farmasöti̇k kompozi̇syonlari
WO2018096517A1 (en) * 2016-11-28 2018-05-31 Parayil Sarin Novel organic crystalline salt of haloacetic acid
TR201618765A2 (tr) 2016-12-16 2018-07-23 Imuneks Farma Ilac Sanayi Ve Ticaret Anonim Sirketi Ağrı ve enflamasyonun tedavisi için steroid olmayan anti-enflamatuvar ilaçlar ve H2 reseptörü antagonisti kombinasyonları.
KR102462607B1 (ko) * 2020-11-11 2022-11-03 대원제약주식회사 펠루비프로펜 신규 염을 주성분으로 하는 안정성이 증가된 약학적 조성물
KR102552315B1 (ko) * 2020-11-11 2023-07-06 대원제약주식회사 펠루비프로펜 신규 염을 주성분으로 하며 위장장애 부작용이 저감된 약학적 조성물
WO2023182869A1 (en) * 2022-03-25 2023-09-28 Ildong Pharmaceutical Co., Ltd. Novel salt of glp-1 receptor agonist compound, preparation method thereof and pharmaceutical composition comprising thereof

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Also Published As

Publication number Publication date
FI952230A (fi) 1995-05-09
HU219975B (hu) 2001-10-28
JPH08503203A (ja) 1996-04-09
HU9501375D0 (en) 1995-06-28
PL175265B1 (pl) 1998-12-31
NO2006007I1 (no) 2006-08-14
RO118712B1 (ro) 2003-09-30
SK280550B6 (sk) 2000-03-13
CA2149013C (en) 2004-08-10
JP3778516B2 (ja) 2006-05-24
BG61723B1 (bg) 1998-04-30
KR100284838B1 (ko) 2001-04-02
US5554789A (en) 1996-09-10
ES2058024B1 (es) 1995-05-01
FI952230A0 (fi) 1995-05-09
NO951790D0 (no) 1995-05-08
NO304306B1 (no) 1998-11-30
UA44233C2 (uk) 2002-02-15
MD921G2 (ro) 1998-10-31
BG99609A (bg) 1996-01-31
CZ114995A3 (en) 1995-10-18
DE69311130T2 (de) 1997-09-18
AU674040B2 (en) 1996-12-05
NZ257557A (en) 1996-01-26
CZ286621B6 (cs) 2000-05-17
DE69311130D1 (de) 1997-07-03
ATE153649T1 (de) 1997-06-15
BR9307408A (pt) 1999-08-24
DK0668851T3 (da) 1997-12-22
SK60395A3 (en) 1995-09-13
AU5421094A (en) 1994-06-08
CA2149013A1 (en) 1994-05-26
HU9802850D0 (en) 1999-02-01
RU2128160C1 (ru) 1999-03-27
RU95112575A (ru) 1997-06-20
ES2058024A1 (es) 1994-10-16
HUT71903A (en) 1996-02-28
NO951790L (no) 1995-07-06
EP0668851A1 (en) 1995-08-30
DE668851T1 (de) 1996-10-10
FI108637B (fi) 2002-02-28
GR960300012T1 (en) 1996-03-31
WO1994011332A1 (en) 1994-05-26
ES2081780T3 (es) 1997-07-01
ES2081780T1 (es) 1996-03-16
GR3024344T3 (en) 1997-10-31
HK1006306A1 (en) 1999-02-19
HU217973B (hu) 2000-05-28
PL308466A1 (en) 1995-07-24
EP0668851B1 (en) 1997-05-28

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Legal Events

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VENC Patent expired

Effective date: 20160314